• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1996년도 제4회 추계심포지움
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• pp.65-73
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• 1996

LPS/LOS, the compound found only in gram-negative bacterial outer membrane, plays important roles in bacterial maintenance as well as its pathogenesis. We isolated and characterized several genes required for NTHi 2019 LOS biosynthesis, which encode enzymes required for sugar substrate synthesis or the transfer of substrates to receptor molecules. The htrB gene, however, appears to have more complex role. It has acryltransferase activity as well as various other activity, which may control regulation of LOS biosynthesis as well as its pathogenicity. Evidences supporting the latter come from the observations that the lipid A of the B29 induced significantly less TNF ${\alpha}$ from macrophages than that of the wild type LOS (unpublished data). H. influenzae A2-htrB mutant strain was also significantly less invasive than the wild type strain. The structural similarities of the enterobacterial LPS and the Haemophilus LOS enabled us to isolate the NTHi 2019 genes involved in LOS biosynthesis genes by using the S. typhimurium LPS deep core mutants. While a similar approach has been used for E. coli, this technique for selection of an LPS phenotype has not been applied to nonenterobacterial species. The difficulties inherent in the molecular manipulation of organism such as Neisseria and Haemophilus species make this approach particularly attractive in the identification and cloning LOS genes. Studies on genetic features of LPS/LOS biosynthesis would be useful for understanding bacterial pathogenesis as well as for developing vaccines for these gram-negative pathogenic bacteria.

• Archives of Plastic Surgery
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• 제48권5호
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• pp.503-510
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• 2021

Facial feminization surgery (FFS) incorporates aesthetic and craniofacial surgical principles and techniques to feminize masculine facial features and facilitate gender transitioning. A detailed understanding of the defining male and female facial characteristics is essential for success. In this first part of a two-part series, we discuss key aspects of the general preoperative consultation that should be considered when evaluating the prospective facial feminization patient. Assessment of the forehead, orbits, hairline, eyebrows, eyes, and nose and the associated procedures, including scalp advancement, supraorbital rim reduction, setback of the anterior table of the frontal sinus, rhinoplasty, and soft tissue modifications of the upper and midface are discussed. In the second part of this series, bony manipulation of the midface, mandible, and chin, as well as soft tissue modification of the nasolabial complex and chondrolaryngoplasty are discussed. Finally, a review of the literature on patient-reported outcomes in this population following FFS is provided.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제47권1호
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• pp.25-33
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• 2021

Objectives: Many conditions of the oral and maxillofacial region require hospitalization and in-patient care. The average length of stay (LOS) of these patients varies and is usually affected by multiple confounding variables. However, even with an increasing number of hospital admissions, published evidence on the factors that affect the LOS of oral and maxillofacial patients is lacking. Therefore, this study assessed the LOS of in-patients at the oral and maxillofacial surgery department of a government-funded, multi-specialty hospital in Malaysia, based on their reasons for admission and other factors. Materials and Methods: Our samples were collected retrospectively over a 5-year period and included patients with maxillofacial infections, post-trauma stabilization, facial bone fracture surgery, benign and malignant lesion surgery, dentoalveolar surgery, and other maxillofacial surgeries as reasons for admission. Factors potentially affecting LOS were also recorded, and their significance was determined using multiple logistic regression analyses. A P-value of less than 0.05 was considered to be statistically significant. Results: A total of 1,380 patients were included in this study. Most (84.5%) of our in-patients were of Malay ethnicity, and males outnumbered females in our sample by 502 subjects. The median LOS of our in-patients was 3 days. Sex, ethnicity, age, reason for admission, and American Society of Anesthesiology (ASA) classification were factors that significantly affected LOS. Conclusion: The median LOS reported in this study was 3 days. LOS was significantly affected by sex, ethnicity, age, reason of admission and ASA classification.

• 대한통합의학회지
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• 제9권3호
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• pp.69-78
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• 2021

Purpose : The purpose of this study was to investigate the effect of stair exercise and Kegel combined exercise on the maximum voluntary ventilation (MVV) and limits of stability (LOS). Methods : 23 female students participated in this experiment. MVV was measured with a spirometer. The LOS was measured with a Biorescue. Subjects were randomly assigned to two groups. 12 subjects were assigned to the experimental group and 11 subjects were assigned to the control group. The experimental group performed 5 minutes of stair exercise and 5 minutes of Kegel exercise. The control group performed 10 minutes of stair exercise. After 5 minutes of exercise, 1 minute of rest was provided. Both groups exercised for 5 minutes according to the metronome beat 130 during the stair exercise. After 5 minutes of rest after exercise, MVV and LOS were measured again in the same way. The measurement sequence was also randomly alternated. Results : Significant differences were found within and between groups in the experimental group in MVV (p<.05). In LOS, significant differences were confirmed in left, right, forward, backward, and total LOS in the experimental group (p<.05). In the control group, there were significant differences in left, forward, and total LOS (p<.05). However, there was no significant difference between groups (p>.05). Conclusion : Based on the results of this study, it was confirmed that the stairs and Kegel combined exercise had a positive effect on MVV and LOS. However, in the short term, it was found that the stair and Kegel combined exercise was insufficient in time and the threshold of exercise to show the difference between groups in LOS. Therefore, additional research should be conducted by modifying the limitations of this study.

• 대한토목학회논문집
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• 제29권3D호
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• pp.335-345
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• 2009

일반적으로 도로시설의 기본구간에 대한 서비스수준(LOS)의 효과척도로 밀도가 사용되지만, 도로시설의 현장에서 관측된 관측밀도와 교통특성자료로부터 산정된 산정밀도사이에는 오차가 발생할 수 있기 때문에 도로시설의 서비스수준을 제대로 나타낼 수가 없다. 따라서 본 연구의 목적은 연구대상 도시고속도로의 본선구간 상에 관측기기를 설치하여 실시간의 교통특성 자료(교통량, 속도, 점유율, 차두시간, 차두거리 등)를 수집 조사하고, 수집 조사된 교통특성자료의 상호관계로부터 연구대상 기본구간 상의 최대 교통류율을 비교 분석하며, 비교 분석된 최대 교통류율을 중심으로 각 서비스수준별 점유율과 v/c비율사이의 관계에 기초하여 도시고속도로의 기본구간에서 서비스수준의 평가기준을 산정 평가하고자 하는데 있다.

• 생물정신의학
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• 제2권2호
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• pp.295-300
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• 1995

Late-onset schizophrenia(LOS) is a controversial entity. It has been thought that onset of schizophrenia is limited to early adulthood, but many European psychiatrists have reported on the occurrence of schizophrenia in late life. DSM-III restricted the diagnosis of schizophrenia to patients with onset of illness before age 45 years. But, DSM-III-R, DSM-IV, and ICD-10 recognize no upper limit to the age at onset of schizophrenia. Patients with LOS have more visual, tactile, and olfactory hallucinations. Patients with LOS have more persecutory delusions, premorbid schizoid personality traits, and less affective blunting. The course of illness was favorable in LOS. We present four cases of LOS. Their detailed clinical features are reported hear with brief review.

• 비파괴검사학회지
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• 제29권4호
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• pp.269-282
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• 2009

This paper presents a novel approach for Lamb wave based structural health monitoring(SHM) in honeycomb aluminum panels. In this study, a suite of three signal processing algorithms are employed to improve the damage detection capability. The signal processing algorithms used include wavelet attenuation, correlation coefficients of power density spectra, and triangulation of reflected waves. Piezoelectric transducers are utilized as both sensors and actuators for Lamb wave propagation. These SHM algorithms are built into a MatLab interface that integrates and automates the hardware and software operations and displays the results for each algorithm to the analyst for side by side comparison. The effectiveness of each of these signal processing algorithms for SHM in honeycomb aluminum panels under a variety of damage conditions is then demonstrated.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2005년도 춘계 학술발표회 논문집
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• pp.1390-1395
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• 2005

To analyze the effects of oyster shell particles, inserted in the self-hardening matrix such as cement paste, on strength, homogenization analysis using micro structure was used to estimate and assess the apparent elastic modulus of oyster shell particle. DIB modeling technique was used to represent of the micro structure of oyster shell mixed concrete. The results showed that the apparent elastic modulus of LOS (large oyster shell particle) was changed with the amount of LOS inserted. In particular, when the amount of LOS was 200% of the weight of cement, the apparent elastic modulus of LOS tended to decrease rapidly. This could mean that the strength of oyster shell mixed concrete is much affected by LOS inserted material in mixed ratio of 200%.

• 제어로봇시스템학회논문지
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• 제16권3호
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• pp.207-214
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• 2010

This paper proposes about decentralized control approach based Leader-Follower formation control using LOS (Line of Sight) algorithm and unknown input observer. The position of robots which is a basic information in multi-robot or single robot motion control is determined by localization algorithm fusing UPS (Ultrasonic Position System) and kinematics model. For formation control, a decentralized control approach individually installing a local controller in leader and follower robot is adopted. Leader robot is controlled to track a specified trajectory by LOS algorithm, and the other robots follow the leader by local controller based on tracking platoon level function, self-sensing data and estimated information from unknown input observer. The performance of proposed method is proven through the formation experiment of two vehicle models.

• 한국통신학회논문지
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• 제21권9호
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• pp.2494-2504
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• 1996

This paper describes about the spread specturm radio wave propagation characteristics in urban microcells. The experiments are carried out with respect to the mean excess delay, the RMS delay spread, and the received maximum peak power in the two kinds of geogrphical areas, LOS area and N-LOS area, especially whose variations are observed while varying the transmission distance and tilting the transmitting antenna. The typical results obtained in pariticular urban sites in Seoul are 300-600 nsec of mean excess delay and about 75 nsec of averaged RMS delay spread for LOS area, and 270-280 nsec of mean excess delay and about 100 nsec for N-LOS area. With the transmitting antenna gilted, obsered in the experiments are increase in RMS delay spread as expected, but increase of the received power at N-LOS areas in particular.