• 농업과학연구
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• 제48권4호
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• pp.655-668
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• 2021

The present study was conducted to investigate the effects of the supplementation of Achyranthes japonica extract (AJE) on overall performance levels with different nutrition concentrations in the diets of finishing pigs. Here, 140 finishing pigs with initial body weights of 50.18 ± 2.37 kg were used in a ten-week trial involving a 2 × 2 factorial design in two phases with the following factors: diet types with different nutrition concentrations (Positive control [PC] vs. Negative control [NC]) and 0 or 0.05% AJE supplementation to NC and PC diets. The PC diet was a basal diet, whereas the NC diet consisted of a 5% and 7% crude protein (CP) reduced basal diet during phase 1 (1 - 35 days) and phase 2 (36 - 70 days), respectively. A significant effect (p < 0.05) on the gain-to-feed ratio (G : F) was observed with interaction effects between the diets and AJE supplementation. However, during phase 1 and in all periods, the pigs fed the PC and NC diets with average daily feed intake (ADFI) tended to decrease compared to those fed diets with AJE. A significant effect (p = 0.0380) of E. coli was observed in pigs fed the PC and NC diets compared to AJE supplementation in phase 2 of the experiment. The backfat thickness (BFT) tended to decrease and the lean meat percentage (LMP) was significantly improved in phase 2 for pigs fed the PC and NC diets. In summary, BFT and LMP showed beneficial effects and fecal microbiota of E. coli counts were positively affected when pigs were fed diets with different nutrient concentrations.

• 미생물학회지
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• 제52권4호
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• pp.482-486
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• 2016

차가버섯(Inonotus obliquus)은 다양한 생리활성을 가진 약용버섯으로 항암, 항산화, 항염효능 등을 가진 것으로 보고되었다. EBV 양성 위암은 EBV관련 암 중 가장 빈번하게 나타나는 형태로 EBV 잠복감염이 그 원인이다. 본 연구에서는 차가버섯 주정추출물의 경구투여를 통해 EBV 양성 인간위암(SNU719) 세포주를 면역결핍 쥐에 주입 후 생기는 고형암 생성억제에 대한 효능을 연구하였다. 또한, 실험종료 후, 각각의 종양조직을 절제하여 항종양 억제기전을 탐구하였다. In vivo 종양생성억제 실험에서 차가버섯은 유의적으로 고형암 생성억제 효능을 보였다. 차가버섯이 투여된 동물유래 종양조직에서 세포자멸사와 관련된 p53, p21 및 Bax의 발현이 크게 증가하였으며, 이는 cleaved caspase-9와 cleaved Parp 발현의 상승과 동반하여 항종양 효능이 세포자멸사를 통해 나타남을 제시하였다. 또한, 이러한 항종양 효능은 세포주 내 잠복되어 있는 EBV 바이러스 유전자인 BZLF-1 및 LMP-2의 발현에도 영향을 미치는 것으로 밝혀졌다.

• IMMUNE NETWORK
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• 제11권1호
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• pp.50-58
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• 2011

Background: Epstein-Barr virus associated gastric lymphoepithelioma-like carcinoma (LELC) is characterized by the intensive infiltration of lymphoid cells, the presence of EBV, and the better prognosis over typical adenocarcinoma. Thus, it was assumable that viral latent proteins may be responsible for the recruitment of a certain T cell repertoire to EBV-associated gastric carcinoma. Methods: To examine above possibility, EBV gene expression in gastric carcinoma tissues and usage of TCR among the tumor infiltrating lymphocytes were analyzed. Results: EBV specific DNA and EBERs RNA were detected in 4 out of 30 patients. RT-PCR analysis revealed that all 4 of EBV-positive tumor tissues expressed EBNA1 mRNA and BARTs and LMP2a was detected only one sample out of 4. However, the EBNA2 and LMP-1 transcripts were not detected in these tissues. $CD8^+$ T cells were the predominant population of infiltrating lymphocytes in the EBV-positive gastric carcinoma. According to spectra type analysis of infiltrating T cells, 10 predominant bands were detected by TCR $V{\beta}$ CDR3 specific RT-PCR from 4 EBV-positive tumor tissues. Sequence analysis of these bands revealed oligoclonal expansion of T cells. Conclusion: These findings suggest that clonally expanded T cells in vivo might be a population of cytotoxic T cells reactive to EBV-associated gastric carcinoma.

• 대한기계학회논문집A
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• 제21권1호
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• pp.22-31
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• 1997

The grain boundary etching method as a method for assessing degradation of structural materials has received much attention because it is simple, inexpensive and easy to apply to real components. In this study, the effectiveness of the method is verified by successfully applying the technique to in-service components of aged fossil power plants such as main steam pipes, boiler headers an turbine rotors. A new degradation parameter, intersecting number ratio (N$_{1}$/N$_{0}$), is employed. The intersecting number ratio (N$_{1}$/N$_{0}$) is defined as the ratio of intersection number (N$_{1}$) obtained from 5-minute picric acid etched surface to the number (N$_{0}$) obtained from nital etched surface. Two kinds of test materials, 2.25Cr-1Mo steel and 1Cr-1Mo-0.25V steel, were artificially thermal-aged at 630.deg. C in different levels of degradation., (N$_{1}$/N$_{0}$) were measured. And, correlations between the measured values and LMP values calculated from aging temperature and aging time were sought. To check the validity of the correlations obtained in laboratory, similar data were measured from service components in four old Korean fossil power plants. These on-site measurement data were in good correlation with those obtained in the laboratory.oratory.

• 대한기계학회논문집
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• 제17권6호
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• pp.1321-1329
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• 1993

본 연구에서는 이들보다 매우 간단한 IS법, 즉 초기 변형률법(ISM: initial strain method)에 의한 크리프 수명예측식을 고안하여, 현재 화력발전용 고압 로터강 에 사용되고 있는 1%Cr-Mo-V강과 발전소 효율향상을 위해 최근 국내최초로 개발된 12% Cr강에 대하여 도출하였고, 이 도출식이 앞에서 언급한 여러 파라메트에 의한 결과와 비교 평가하여 장시간 강도 및 수명예측식으로 사용될 수 있음을 입증하였다.

• 한국해양공학회지
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• 제12권2호통권28호
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• pp.71-78
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• 1998

In this report for the assessment of creep properties of high-temperature tube materials in power plants, the long-time($10^4$~105h) creep life prediction by ISM for 2.25Cr1Mo steel was studied. It was clarified experimentally and quantitatively that the newly developed long-time creep life prediction equation was very coincident with the actual experimental data with high confidence, and the model was $t_r=\alpha\varepsilon_0^{\beta}\sigma^{-1}$.

• Rapid Communication in Photoscience
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• 제1권2호
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• pp.58-58
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• 2012

• Advances in concrete construction
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• 제12권6호
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• pp.461-467
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• 2021

Polyethylene-terephthalate (PET) from bottle waste and linear low-density polyethylene (LLDPE) from barrels and tanks waste are widely available and need to be recycled. Recycling them in concrete and mortar is an alternative solution for their disposal. In this study various quantities of sand (5%, 10%, 15% and 20%) were substituted by powder from LLDPE waste. In addition, PET waste fibers (corrugated, straight) were added to the mortar with different percentages (0.5%, 1%, 1.5% and 2%) of cement mass. This paper evaluate the mechanical and physical properties of the composites in fresh (workability, air content and density) and hardened state (compressive and flexural strength, water absorption and total shrinkage). From the experimental results, it can be concluded that the strengthening in tensile of the mortar with plastic waste corrugated fibers is improved. Other important results are that the water absorption and the density rate are less than that of the ordinary mortar.

• 한국해양공학회지
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• 제25권4호
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• pp.12-17
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• 2011

Little design data is available for the creep life prediction of 9% Ni alloy in elevated temperatures. Therefore, in this study, a series of creep tests under 16 combined conditions with 4 kinds of stresses and 4 temperatures was performed to obtain creep design and life prediction data for 9% Ni alloy, with the following results. The stress exponents decreased as the test temperature increased. The creep activation energy gradually decreased as the stresses became larger. The Larson-Miller parameter (LMP) constant for this alloy was estimated to be about 2.

• 동력기계공학회지
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• 제5권2호
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• pp.57-62
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• 2001

Gas turbine performance is highly dependent on the engine performance which is closely related to the engine materials since they are exposed to severe working environments, i.e, high temperature and high stresses. For this reason, advanced materials with improved properties are required for the engine. The purpose of this research is to develop key materials technologies for aircraft industry and to tester domestic production of related parts. In this paper, the real-time prediction of high temperature creep strength and creep life for nickel-based superalloy Udimet 720(high-temperature and high-pressure the gas turbine engine materials) was performed on round-bar type specimens under pure load at the temperatures of 538, 649 and $704^{\circ}C$.