• Title/Summary/Keyword: LLD

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Development of Multiwire Proportional Counter for Measurement of Environmental-level Alpha Particles (환경준위 알파입자측정을 위한 다중선 비례계수기 개발(I))

  • Oh, Pil Jae;Park, Tae Soon;Lee, Min Kie;Kim, Kyung Hwa
    • Analytical Science and Technology
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    • v.9 no.3
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    • pp.262-269
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    • 1996
  • The muiltiwire proportional counter for the measurement of low-level and environmental $\alpha$ particles emitting nuclides was developed. External dimension of the devloped multiwire proportional counter is $350{\times}290{\times}30mm$ and the sensitivity area is $250{\times}200mm$. The wall material of the detector was selected the stainless steel to prevent the deformation by external impact and to obtain minimum background. The anode and cathode wires were used the stainless steel material of diameter $50{\mu}m$. The spacing of each wires are 10.0mm, 5.0mm and the numbers of total wire are 21, 42 lines, respectively. The multiwire proportional counter was designed that the measurement source is placed within the detector to prevent the wall absorption effect and the efficiency variation by various source heights. The characteristics of the developed detector have been investigated to obtain the plateau, operating voltage, background, counting efficiency, position sensitivity and energy resolution etc. For the $^{241}Am$ nuclide, the calculated LLD(Lower Limit of Detection) is 5.0mBq/L which is lower than 40mBq/L of recommended LLD value by ISO(International Organization for Standardization).

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Clinical Significance of Restless Legs Syndrome in Patients with Late Life Depression (노년기 우울증 환자의 하지불안증후군의 임상적 중요성)

  • Song, Jae Min;Park, Joon Hyuk;Kang, Ji Eon;Lee, Chang In
    • Korean Journal of Biological Psychiatry
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    • v.21 no.3
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    • pp.107-113
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    • 2014
  • Objectives Restless legs syndrome (RLS) is a sleep disorder characterized by uncomfortable and unpleasant sensations in the legs and an urge to move the legs, usually at night. The aim of this study is to investigate the incidence of RLS in patients with late life depression and its influence on various clinical outcomes such as severity of depression, sleep quality, cognitive function, and quality of life and accordingly, to elucidate the clinical significance of RLS in patients with late life depression (LLD). Methods This study enlisted 170 depressive patients aged 65 years or older from an outpatient clinic. Structured diagnostic interviews were performed using the Korean version of the Mini-International Neuropsychiatric Interview. All patients completed the questionnaires, including the International RLS Severity Scale, the Korean version of Short-Form 36-Item Health Survey (SF-36), and the Pittsburgh Sleep Quality Index (PSQI). The severity of depression was evaluated by the Korean form of the Geriatric Depression Scale (KGDS) and the level of global cognition was assessed by the Mini-Mental State Examination in the Korean version of The Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (MMSE-KC). Results The incidence of RLS was 17.6% in LLD patients. RLS was more prevalent among the subjects with major depressive disorder (MDD) than those with minor depressive disorder or subsyndromal depressive disorder. The RLS group showed higher score in the KGDS than the Non-RLS group but the difference did not reach the statistical significance (p = 0.095, Student t-test). The mean PSQI score was significantly higher in the RLS group than in the Non-RLS group (p = 0.001, Student t-test). The MMSE-KC score was also lower in the RLS group than in Non-RLS group (p = 0.009, analysis of covariance). But, there was no difference in the score of SF-36 between the RLS group and the Non-RLS group. Conclusions RLS is common in LLD patients, especially in the patients with MDD and is associated with poor sleep quality and cognitive dysfunction, indicating that RLS is clinically significant in patients with LLD. Therefore, RLS should be considered as an important clinical issue in the management of LLD.

Association of A/T Rich Microsatellites with Responses to Artificial Selection for Larval Developmental Duration in the Silkworm Bombyx mori

  • Pradeep, Appukuttan Nair Retnabhavan;Awasthi, Arvind Kumar;Urs, Raje Siddaraje
    • Molecules and Cells
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    • v.25 no.4
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    • pp.467-478
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    • 2008
  • Simple sequence repeats (SSRs) and interSSR (ISSR) marker systems were used in this study to reveal genetic changes induced by artificial selection for short/long larval duration in the tropical strain Nistari of the silkworm Bombyx mori. Artificial selection separated longer larval duration (LLD) ($29.428{\pm}0.723days$) and shorter larval duration (SLD) ($22.573{\pm}0.839days$) lines from a base, inbred population of Nistari (larval span of $23.143{\pm}0.35days$). SSR polymorphism was observed between the LLD and SLD lines at one microsatellite locus, Bmsat106 ($CA_7$) and at two loci of 1074 bp and 823 bp generated with the ISSR primer UBC873. Each of these loci was present only in the LLD line. The loci segregated in the third generation of selection and were fixed in opposite directions. In the $F_2$ generation of the $LLD{\times}SLD$ lines, the alleles of Bmsat106 and $UBC873_{1074bp}$ segregated in a 1:1 ratio and the loci were present only in the LLD individuals. $UBC873_{823bp}$ was homozygous. Single factor ANOVA showed a significant association between the segregating loci and longer larval duration. Together, the two alleles contributed to an 18% increase in larval duration. The nucleotide sequences of the $UBC873_{1074bp}$ and $UBC873_{823bp}$ loci had 67% A/T content and consisted of direct, reverse, complementary and palindromic repeats. The repeats appeared to be "nested" (59%) in larger repeats or as clustered elements adjacent to other repeats. Of 203 microsatellites identified, dinucleotides (67.8%) predominated and were rich in A/T and T/A motifs. The sequences of the $UBC873_{1074bp}$ and $UBC873_{823bp}$ loci showed similarity (E = 0.0) to contigs located in Scaffold 010774 and Scaffold 000139, respectively, of the B. mori genome. BLASTN analysis of the $UBC873_{1074bp}$ sequence showed significant homology of (nt.) 45-122 with upstream region of three exons from Bombyx. The complete sequence of this locus showed ~49% nucleotide conservation with transposon 412 of Drosophila melanogaster and the Ikirara insertions of Anopheles gambiae. The A + T richness and lack of coding potential of these small loci, and their absence in the SLD line, reflect the active process of genetic change associated with the switch to short larval duration as an adaptation to the tropics.

The characteristics of poly-Si TFTs with various LDD (LDD 길이 변화에 따른 poly-Si TFT의 특징)

  • Son, Hyuk-Joo;Kim, Jae-Hong;Lee, Jeoung-In;Yi, Jun-Sin
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.06a
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    • pp.93-94
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    • 2007
  • 다양한 LDD(lightly doped drain)에 따른 n-channel poly-Si TFT (thin film transistor)에 대하여 보고한다. 유리 기판 위에 ELA를 이용하여 만들어진 Polycrystalline silicon (poly-Si)은 TFT-LCD의 응용을 위한 재료로써 우수한 특성을 갖는다. 제작된 n-channel TFT는 절연층으로 $SiN_x$, $SiO_2$의 이중 구조를 갖는다. 다양한 LDD에 따른 n-channel poly-Si TFT의 문턱전압($V_{TH}$), ON/OFF 전류비 ($I_{ON}/I_{OFF}$), 포화전류($I_{DSAT}$)는 TFT의 보다 좋은 성능을 위해 연구된다. 짧은 LLD 길이를 가진 n-channel poly-Si TFT의 문턱전압은 작고, 포화전류의 값은 크다. 또한 긴 LLD 길이를 가진 n-channel poly-Si TFT는 작은 kink effect를 가진다.

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Quality Assessment of Cook/chilled Soy Sauce Glazed Soybean Curd Packaged with Different Methods for the Development of Health-oriented Convenience Foods (한국형 건강편의식 개발을 위한 두부조림의 Cook/Chill 생산 및 포장방법에 따른 품질 평가)

  • Kwak, Tong-Kyung;Shon, Shi-Nae;Yoon, Sun;Park, Hye-Won;Ryu, Kyung;Hong, Wan-Soo;Jang, Hye-Ja;Moon, Hye-Kyung;Choi, Jung-Hwa
    • Korean journal of food and cookery science
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    • v.16 no.2
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    • pp.99-111
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    • 2000
  • The purpose of this study was to assess the qualities of cook/chilled soy sauce-glazed soybean curd with various packaging conditions as a trial to develop health-oriented convenience foods. The effects of three packaging methods, linear low density-polyethylene (LLD-PE), top sealing, and modified atmosphere packaging(MAP) on the shelf-life of HACCP-based cook/chilled soy sauce-glazed soybean curd were evaluated during 20 days of chilled storage in terms of time-temperature, microbiological (total aerobic plate count, psychrotrophic plate count, coliform, and fecal coliform count), chemical(pH and peroxide value(POV)), and sensory evaluation. The results of microbiological and chemical analyses were within the limits of the microbial and chemical standards for all phases after cooking. No significant differences were detected in microbial counts of the samples for all three packaging methods. However, sensory evaluation indicated that the top sealing and MAP methods showed a longer shelf-life than LLD-PE packaging. Recommended shelf-life of the product was 12 days for LLD-PE packaging, and 16 days for both top sealing and MAP. In conclusion, MAP was considered as the most effective packaging method for assuring microbial and sensory quality of this cook/chilled product.

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Effect of Leg Length Discrepancy on Gait and Cobb's Angle

  • Park, Ki Han;Kim, Kew Wan;Kim, Chol Hee
    • Korean Journal of Applied Biomechanics
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    • v.26 no.1
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    • pp.101-113
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    • 2016
  • Objective: The purpose of this study was to investigate the effect of leg length discrepancy (LLD) on the human body during gait and standing posture. Methods: The study group comprised of 17 adult participants with LLDs of <1 cm. LLDs were artificially induced to 0, 1, 2, and 3 cm. The proportion of weight distribution, shift of the mean center of pressure, and Cobb's angle were measured in the standing position. Kinematic variables such as walking and striding width and time, and the proportion of stance phase for single- and double-limb gait were measured as well. The participants were required to either stand or walk on a treadmill (Zebris FDM) with a pressure plate, and the Cobb's angle measurements were obtained from radiographs. Results: A discrepancy of 3 cm in leg length resulted in a statistically significant shift of the center of pressure in the standing position. Moreover, the Cobb angle increased as the discrepancy became larger. The step length and width of the longer (left) leg during gait statistically significantly increased when the discrepancy was 2 cm. In addition, step time was statistically significant when the discrepancy between the longer (right) and shorter (left) legs was more than 2 cm. The proportion of single-limb stance phase was statistically significant as the discrepancy became larger, especially when the discrepancy was >2 cm for the longer (right) leg and 1 cm for the shorter (right) leg. Conclusion: The study showed that LLD influenced deformations of the human body and walking.

Effects of Artificial Leg Length Discrepancies on the Dynamic Joint Angles of the Hip, Knee, and Ankle During Gait

  • Kim, Yong-Wook;Jo, Seung-Yeon;Byeon, Yeoung-In;Kwon, Ji-Ho;Im, Seok-Hee;Cheon, Su-Hyeon;Kim, Eun-Joo
    • Journal of the Korean Society of Physical Medicine
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    • v.14 no.1
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    • pp.53-61
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    • 2019
  • PURPOSE: This study examined the dynamic range of motion (ROM) of the hip, knee, and ankle joint when wearing different shoe sole lifts, as well as the limb asymmetry of the range according to the leg length discrepancy (LLD) during normal speed walking. METHODS: The participants were 40 healthy adults. A motion analysis system was used to collect kinematic ROM data. The participants had 40 markers attached to their lower extremities and were asked to walk on a 6 m walkway, under three different shoe lift conditions (without an insole, 1 cm insole, and 2 cm insole). Visual3D professional software was used to coordinate kinematic ROM data. RESULTS: Most of the ROM variables of the short limbs were similar under each insole lift condition (p>.05). In contrast, when wearing a shoe with a 2 cm insole lift, the long limbs showed significant increases in flexion and extension of the knee joint as well as; plantarflexion, dorsiflexion, pronation, eversion, and inversion of the ankle joint (p<.05). Of the shoes with the insole lifts, significant differences in all ROM variables were observed between the left and right knees, except for the knee internal rotation (p<.05). CONCLUSION: As the insole lift was increased, more ROM differences were observed between the left and right limbs, and the asymmetry of the bilateral lower limbs increased. Therefore, appropriate interventions for LLD are needed because an artificial mild LLD of less than 2.0 cm could lead to a range of musculoskeletal problems of the lower extremities, such as knee and ankle osteoarthritis.

Characteristics of $CaSO_4$:Dy TL Dosimeters by Determining LLDs, Fadings and Sensitivity Changes in Repeat Uses (최소검출한계, 잠상퇴행 및 반복사용으로 인한 감도면화 결정에 의한 $CaSO_4$:Dy 열형광선량계 특성)

  • Kim, Jang-Lyul;Kim, Bong-Hwan;Chang, Si-Young;Lee, Hyung-Sub;Lee, Jae-Ki
    • Journal of Radiation Protection and Research
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    • v.22 no.3
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    • pp.161-170
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    • 1997
  • Theoretical and experimental determination of the lower limits of detection (LLD) of C-300-A $CaSO_4$:Dy TL dosimeters which are currently used for the personnel monitoring in Korea Atomic Energy Research Institute(KAERI) are described with a critical level which is defined as the signal level above which a result has a probability of being due to a fluctuation of the background. The personnel monitoring processors can derived easily the LLD of their system using this method with the background readings of their service interval and the irradiation readings of the known doses. Experimental studies were also conducted for the fading rates of the dosimeters with the temperatures and humidities for 3 months. Finally sensitivity changes in repeat uses were measured for 40 times consecutive uses of the dosimeters. The applications of the experimental results of fading rates and sensitivity changes in real personnel monitoring services are discussed briefly.

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Long-term Location Data Management for Distributed Moving Object Databases (분산 이동 객체 데이타베이스를 위한 과거 위치 정보 관리)

  • Lee, Ho;Lee, Joon-Woo;Park, Seung-Yong;Lee, Chung-Woo;Hwang, Jae-Il;Nah, Yun-Mook
    • Journal of Korea Spatial Information System Society
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    • v.8 no.2 s.17
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    • pp.91-107
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    • 2006
  • To handling the extreme situation that must manage positional information of a very large volume, at least millions of moving objects. A cluster-based sealable distributed computing system architecture, called the GALIS which consists of multiple data processors, each dedicated to keeping records relevant to a different geographical zone and a different time zone, was proposed. In this paper, we proposed a valid time management and time-zone shifting scheme, which are essential in realizing the long-term location data subsystem of GALIS, but missed in our previous prototype development. We explain how to manage valid time of moving objects to avoid ambiguity of location information. We also describe time-zone shifting algorithm with three variations, such as Real Time-Time Zone Shifting, Batch-Time Zone Shifting, Table Partitioned Batch-Time Zone Shifting, Through experiments related with query processing time and CPU utilization, we show the efficiency of the proposed time-zone shifting schemes.

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Inhibition Effect of Bacillus subtilis on 365 nm UV-LED Irradiation According to Packaging Materials (포장재 조건에 따른 365 nm UV-LED 조사의 Bacillus subtilis 생육 억제 효과)

  • Lee, Da-Hye;Jeong, So-Mi;Xu, Xiaotong;Kim, Koth-Bong-Woo-Ri;Ahn, Dong-Hyun
    • Microbiology and Biotechnology Letters
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    • v.47 no.3
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    • pp.332-336
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    • 2019
  • The use of ultraviolet (UV) spectroscopy for foods is known to have a microbial inhibitory effect. UV-A having a longer wavelength than UV-C can be used for continuous or intermittent UV irradiation of food stored in containers or packages. Because UV-LED can be used effectively at a low price, this study reported the effect of UV-A 365 nm-LED on inhibiting Bacillus subtilis in accordance with the packaging conditions employed in daily use. The packaging materials were linear low-density polyethylene (LLD-PE), nylon/low density polyethylene (LDPE), polystyrene, and glass. When all packaging materials were treated with 365 nm UV-LED, B. subtilis was observed to remain inactive for 30-60 min. Further, compared with the control (-log 5), the survival rate of B. subtilis was -log 2.0-2.5 for nylon/LDPE and -log 2.58-3.61 for LLD-PE. These packaging materials showed an excellent inhibitory effect regardless of their thickness. Typically, a decrease in the viable cell count of more than 3 log indicates a 99.9% bactericidal effect. These results suggest that 365 nm UV-LED permeated the packaging material and inhibited bacterial growth.