• Korean Journal of Clinical Laboratory Science
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• v.47 no.4
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• pp.298-305
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• 2015

Stem cell-like tumor cells are reported to be the main reason for tumor recurrence and metastasis. As one of the new approaches to overcome cancer, studies are emerging to inhibit the expressions of stem cell transcriptional factors (Oct4, Sox2, Klf-4, and Lin28) in cancer cells. MicroRNAs are master genetic regulators that can control development and differentiation of stem cells. In this study using various ovarian tumors (Skov3, Ovcar3, Tov112D, Tov21G, PA-1 and Hsc832(c)T), we examined the expressions of stem cell-related transcription factors, and the biological changes in cell survival and growth by miR-126 that targets stem cell transcriptional factors. We observed that treatment of miR-126 induced the morphological changes and cell suspension in most cells. In addition, miR-126 induced gradual regression of cell division except Skov3 cells, especially significant time-dependent reduction in Tov112D, Tov21G and PA-1. When we examined the expression of stem cell transcriptional factors, Sox2 was shown to be down-regulated after miR-126. Our results demonstrate that miR-126 treatment can provide the reversible environment to regulate cell division and to induce cell death of ovarian tumors, suggesting the molecular biological clues for clinical usage.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.23 no.3
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• pp.359-370
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• 2013

Lin and Chan proposed a reversible secret image sharing scheme in 2010. The advantages of their scheme are as follows: the low distortion ratio, high embedding capacity of shadow images and usage of the reversible. However, their scheme has some problems. First, the number of participants is limited because of modulus prime number m. Second, the overflow can be occurred by additional operations (quantized value and the result value of polynomial) in the secret sharing procedure. Finally, if the coefficient of (t-1)th degree polynomial become zero, (t-1) participants can access secret data. In this paper, an improved reversible secret image sharing scheme which solves the problems of Lin and Chan's scheme while provides the low distortion ratio and high embedding capacity is proposed. The proposed scheme solves the problems that are a limit of a total number of participants, and occurrence of overflow by new polynomial operation over GF($2^8$). Also, it solve problem that the coefficient of (t-1)th degree polynomial become zero by fixed MSB 4-bit constant. In the experimental results, PSNR of their scheme is decreased with the increase of embedding capacity. However, even if the embedding capacity increase, PSNR value of about 45dB or more is maintained uniformly in the proposed scheme.

• Journal of the Korean association of regional geographers
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• v.15 no.6
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• pp.720-735
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• 2009

This paper studies the characteristics of the restructuring of chemical industrial complex in JiLin city since 1978 focusing on enterprise organization, the process of production, labor, and consumer market. The number of chemical industrial enterprises and their partnership with subcontractors have increased since 2001. As for the type of cooperation group, research institutes and local government are accounted for the greatest portion. The chemical industrial enterprise in JiLin which has adopted Fordism production method still has the highest percentage in 2007. And in the shift process of production system after China's entry into WTO(in 2001), chemical industrial enterprise in JiLin city takes allowing more investment in production technologies as core strategy, while taking improvement in equipment and development of new products as core strategy in the shift process of production technology. The degree of labor re-education was highest in 2007, and as for the relationship between labor and management, enterprises which evaluate the ability of performance of duty are increasing. The characteristics of restructuring of chemical industrial complex on consumer market, domestic market accounted for the greatest portion, on the other side the export is feeble. As for strategy of market restructuring, industrial enterprise in JiLin city should use Quality improvement and high-value added as core strategies to cope with alteration of market.

• Journal of Animal Science and Technology
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• v.44 no.6
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• pp.783-792
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• 2002

This experiment was conducted to investigate the effects of supplementary level of extruded poultry manure, corn and tapioca mixture (EPM) on growth performance, nutrient digestibility and body composition in korean native goats. Total 15 heads of Korean native goats (10 kg B.W.) were randomly assigned into five treatment groups (EPM 10, 20, 30, 40% and control.) and feeding trial was done for six weeks with ad libitum. Protein level of the extrudate with poultry manure was directly proportional to corn supplements rate. NFE and Ca content in EPM also were functional of the tapioca supplements levels. Daily body weight gain was significantly (p<0.05) reduced in EPM 40% group, but no significant differences were observed in other groups. Concentrate feed intake was high in EPM 10 to 30% groups, compared to the control. Feed conversion ratio also was relatively higher in EPM groups than in the control. As EPM level increased, dry matter digestibility was proportionally decreased, but that of crude protein was enhanced. Dressed carcass percentage was significantly (p<0.05) reduced with the increase of EPM level, showing control 49.7, EPM 10% 49.8, EPM 20% 48.3, EPM 30% 47.9 and EPM 40% 45.2, respectively.

• Proceedings of the Korean Magnestics Society Conference
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• 2007.05a
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• pp.240.2-240.2
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• 2007

• Proceedings of the Korean Magnestics Society Conference
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• 2007.05a
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• pp.123.2-123.2
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• 2007

• The Korea Genome Conference
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• 2006.09a
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• pp.78-78
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• 2006

• Proceedings of the Korean Fiber Society Conference
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• 1993.06b
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• pp.79-89
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• 1993

• Proceedings of the Korean Vacuum Society Conference
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• 2001.02a
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• pp.23-24
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• 2001

• Journal of the Korean Professional Engineers Association
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• v.38 no.2
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• pp.64-65
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• 2005