• Proceedings of the KIEE Conference
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• 2000.07c
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• pp.2081-2082
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• 2000

서강대교와 같은 장경간 교량에 초고압 전력케이블을 설치하는 경우에는 교량의 큰 신축을 흡수하기 위하여 케이블을 장대옵셋으로 설치하는 것이 불가피하게 되고, 장대옵셋 케이블이 균등하게 변형할 수 있도록 신축균등흡수장치를 실증시험을 통하여 국내에서 최초로 개발하고 154kV 중여T/L 구간중 서강대교에 총12기를 설치 완료하였다. 본 고에서는 그 개요를 소개하고자 한다.

• 한국정보디스플레이학회:학술대회논문집
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• 2004.08a
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• pp.799-802
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• 2004

In this paper, the active backlight control technology with data processing algorithm was developed in order to improve image quality for IPS-mode LCD-TV applications. The image blinking problem caused by repeatedly abrupt change of the backlight luminance was solved by algorithms-Fba(Flexible Boundary algorithm) and Cfa(Cumulative Feedback algorithm)-and the optimized number and space of backlight dimming steps based on perception. In the IPS-mode 42" TFT-LCD panel, the dynamic contrast ratio can be more than twice the typical level by means of lower block luminance and higher white luminance. Additionally, Power consumption and LCD temperature was decreased.

• 한국정보디스플레이학회:학술대회논문집
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• 2005.07b
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• pp.944-947
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• 2005

Highly stable gate driver circuit using a-Si TFT has been developed. The circuit has dual-pull down structure, in which bias stress to the TFTs is relieved by alternating applied voltage. The circuit has been successfully integrated in 4-in. QVGA and 14-in. XGA TFT-LCD with a normal a-Si process, which are stable for over 2,000 hours at $60^{\circ}C$. The enhancement of stability of the circuit is attributed to retarded degradation of pull-down TFTs by AC driving.

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.1247-1249
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• 2009

We have successfully developed the 22 inch WSXGA+ DLS(Data Line Sharing) Panel driving in 75 Hz. In the large size and high resolution panels, it is very difficult to design the DLS Panels without failure because of the very short charging time and the large signal delay. So, we first investigated the charging order to find the most adequate charging type to the large size and high resolution panels. And then, we optimized the design of DLS in terms of improving the charging properties using the technologies of the Delta-doping TFTs, Cu metal electrodes and optimization of panel design value and the circuit signal timing.

• Archives of Pharmacal Research
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• v.22 no.2
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• pp.157-164
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• 1999

LB50016 was characterized as a selective and potent$ 5-HT_{1A}$ receptor agonist and evaluate it anxiolytic and antidepressant activities. It shows high affinity for $ 5-HT_{1A}$receptor, moderate affinity for $\alpha$2 adrenergic and $ 5-HT_{2A}$receptors and no significant affinity for other receptors tested. Hypothermia and increased serum corticosterone level were observed in LB50016-treated rats, which are mediated mostly by post synaptic $ 5-HT_{1A}$ receptor activation. In the mouse forced swim model for depression, LB50016-elicited dose-dependent reductions in immobility time, showing $ED_{50}$ of approximately 3 mg/kg i.p., which was blocked by pretreatment of NAN-190, $ 5-HT_{1A}$antagonist. In face-to-face test for anxiolytic activity in mice, estimated $ED_{50}$ was 2 mg/kg, i.p.. In isolation-induced aggression test with mice, fifty-fold increases in latency to attack were observed at 30 min and last up to 4 h after LB50016 treatment (3 mg/kg, i.p.). Taken together, LB50016-induced pharmacological activities are mediated by activation of $ 5-HT_{1A}$receptors, offering an effective therapeutic candidate in the management of anxiety and depression in humans.

• The Korea Journal of Herbology
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• v.35 no.3
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• pp.1-8
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• 2020

Objectives : In this study, we examined the estrogenic activities and anti-osteo clastogenesis effects of PCE17, a mixture of PE (an extract of Puerariae Flos), and CE (an extract of Citri Unshius Pericarpium). Methods : The estrogenic effect of PCE17, PE and CE were examined by ER-β/ERE reporter gene assay and proliferation assay in 293 T and MCF-7 cells. The expression of estrogen-responsive gene and protein were checked by Real Time-PCR (RT-PCR) and Western blotting in MCF-7 cells. Inhibitory effect of PCE17, PE and CE on RANKL-induced osteoclast differentiation were evaluated by TRAP staining and RT-PCR in primary osteoclast precursors from rat bone marrow cells. Results : PCE17 and PE bind to ERs (estrogen receptors) and show estrogenic activities in 293T cells. They also stimulated the proliferation of MCF-7 cells and increased the expression of ER response gene, pS2. Tectorigenin, an active ingredient of PE, shows similar estrogenic activities in MCF-7 cells. PCE17 and CE inhibited RANKL-induced osteoclastogenesis in rat primary osteoclast precursor cells and down-regulated the osteoclast-specific genes of Nfatc1, Ctsk, and Acp5. Conclusions : In conclusion, PCE17 may have therapeutic potential in cases of menopause and osteoporosis.

• The Korea Journal of Herbology
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• v.24 no.4
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• pp.101-106
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• 2009

Objectives : We investigated the anti-aging effects on skin with 9 Repetitive steaming and fermenting herbal composition extract (FHE). Methods : Herbal composition is comprised of Panax Ginseng, Rehmannia glutinosa, Polygonum multiflorum and Polygonatum Sibiricum. They steamed and fermented with Saccharomyces cerevisiae and Lactobacillus brevis by turns at 9 times. We measured various effects related to skin aging such as scavenging activity against free radical, cell proliferation, collagen synthesis and toxicity of 9 repetitive steaming and fermenting herbal composition extract were evaluated and compared with herbal composition extract (HE). Results : As the number of steaming and fermenting cycle increased free-radical scavenging activity were increased. But cell proliferating ratio was not increased when the number of steaming and fermenting cycle. The FHE could significantly increase the collagen synthetic ratio compared with HE treated group. And, FHE was showed no toxicity at all tested concentrations. Conclusions : The results of our study propose that FHE has good anti-aging effects on skin.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.46 no.1
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• pp.81-88
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• 2020

Diesel particulate matter (DPM) induces inflammatory cytokines in HaCaT and stimulates XRE promoter activity through AhR binding. Thus, it increases CYP gene family expression. In this study, we have elucidated inhibitory effect of LG Herbal Medicine Complex (LG-HMC) on DPM-induced XRE promoter activity and inflammatory cytokine expression. First of all, the XRE promoter activity was overexpressed by DPM treatment and the LG-HMC abrogated the XRE promoter activity. Morus alba bark extract, Scutellaria baicalensis root extract and constituents of LG-HMC, were found to be main effecters against DPM induced XRE promoter activation. We also found that DPM treatment elevated inflammatory cytokines in HaCaT and the treatment of LG-HMC, Morus alba bark extract and Scutellaria baicalensis root extract down-regulated the DPM induced inflammatory cytokine expression. Additionally, Morus alba bark extract and Scutellaria baicalensis root extract were found to act as free radical scavengers. In conclusion, we confirmed skin protective effect of LG-HMC and uncovered two components, Morus alba bark extract and Scutellaria baicalensis root extract, that play major role in protecting epidermal kertinocytes from damage.

• Korean Architects
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• s.646
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• pp.36-41
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• 2023

• Information Display
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• v.24 no.1
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• pp.11-27
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• 2023