• Journal of Oriental Neuropsychiatry
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• v.23 no.3
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• pp.47-62
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• 2012

Objectives : This study is to figure the relations of the heart rate variability, body component analysis and accompanying symptoms of 350 insomnia patients. Methods : For this study we evaluated Heart Rate Variability(HRV) and body component analysis on 350 insomnia patients who visited Dongeui oriental hospital of Dongeui university from January 2008 to March 2012. The accompanying symptoms was collected based on each patient's progress note. Results : 1. There was no difference between PR, LF and VLF of male and female groups. HF was higher in the patients' of female group and LF/HF ratio was higher in the male group. The patients' group of age under 39 had higher HF, LF, VLF and LF/HF ratio than the group over 39. 2. The average of LF was the smallest, and the average of VLF was in the middle, while the average of HF was the largest. 3. Regarding patients' age and gender, as the patients' age increased, their HF, LF, VLF and LF/HF ratio decreased significantly. HF, LF, VLF, and LF/HF ratios were, however, independent on the patients' gender. As the patients' age increased, their BMI increased, while the patients' gender did not affect on their BMI. The amount of visceral fat increased with the patients' age, but wasn't dependent on the patients' gender. 4. As the patients' BMI increased, PR and LF decreased. As the patients' amount of visceral fat increased, PR, HF, LF and VLF decreased. 5. The most frequent accompanying symptoms of the insomnia patients was headache. Neither HF nor LF/HF ratio was dependant on any of the accompanying symptoms. Patients with anxiety showed significantly higher LF than those without anxiety. Patients with fatigue and physical pain showed significantly higher VLF than those without either of them. Conclusions : The study showed that as the insomnia patients age increased, the HF, LF, VLF, LF/HF ratio significantly decreased, but the BMI and visceral fat increased. The HF, LF, VLF, LF/HF ratio BMI, or the visceral fat was independent on the gender. As BMI increased, PR and LF decreased. As visceral fat increased, PR HF, LF and VLF decreased. Patients presenting anxiety had higher LF. Patients either with fatigue or physical pain had higher VLF. Neither HF nor LF/HF ratio had any significant correlation with any of the accompanying symptoms.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.18 no.3
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• pp.66-74
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• 2005

Objective: Stress is one of the most important etiological factors in our lives. Human body makes effort to keep his homeostasis from stress by using autonomic nerve system. So we need markers which can evaluate autonomic nerve system easily. HRV represents such markers. Sympathetic and Parasympathetic nerve system are part of autonomic nerve system, related with cur body and diseases in ENT, Dermatology, Ophthalmology are also deeply related with stress, Sympathetic and Parasympathetic nerve system. So we can expect that it can help understanding patients to evaluate autonomic nerve system with HRV Research Methods and Procedures: Forty one patients who have seif-recognized stress in Dept. of Oph & Otolaryngo & Dermatology were selected. SDNN. RMSSD, LF, HF, norm-LF, norm-HF, LF/HF ratio, LnLF, LnHF were checked. Results: Men showed lower SDNN, HF, and LnHF than women(p<0.05). Age over-forty group showed significant lower SDNN, LF, HF, LnLF, LnH(p<0.01), and lower RMSSD(p<0.05) than age under-forty group. There's no big differences for age at norm-LF, norm-HF, and LF/HF ratio. Skin disease group showed higher SDNN, RMSSD, LF, HF, LnLF, LNHF than the others, facial palsy group showed higher norm-HF. LF/HF ratio, and mouth-throat group showed higher norm-LF, but there's no statically significant difference. Comparing skin disease group with the others, the others showed statically significant low SDNN(P<0.01), RMSSD, LF, HF, LnLF and LnHF(P<0.05).

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.21 no.2
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• pp.142-153
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• 2008

Objective : Etiologically, stress is a important factor to immune system and skin disease. Human body is controled to keep his homeostasis from stress by autonomic nerve system. So we investigated autonomic nerve balance and stress level of patients with skin disease by heart rate variability(HRV) test. Research Methods and Procedures : Fifty two patient(from 15 years old to 35 years old) who visited Dept. of Oriental medical Dermatology, Kyunghee university at first and had an examination by HRV test, were selected as the subject of our study. We checked items of HRV test(such as SDNN, RMSSD, VLF, LF, HF, TP, norm-LF, norm-HF, LF/HF ratio, LnHF and LnHF), and analyzed time and frequency domain by sex, age, onset, color on end of patient's tongue, sweating and sleep condition. Results and Conclusion : Men showed significant higher SDNN, RMSSD, LF, norm-LF, norm-HF, LF/HF ratio, LnLF and LnHF than women(p <0.05). Patients who were attacked by skin disease within 6 months, showed significant higher TP and VLF than over 6 months(p <0.05). Patients with normal color on the end of their tongue showed significant higher TP and VLF than with flare color. We analyzed correlation to color on the end of tongue and RMSSD. Prevalence risk(RMSSD <20ms) in the case of normal color on the end of tongue was 5 times as high as in the case of flare color(p <0.1). And we analyzed correlation to age and LF/HF ratio. Prevalence risk(LF/HF ratio <1) of patients from 15 years old to 25 years old was 1.467 times as high as from 26 years old to 35 years old(p <0.1).

• Journal of the Korean Society of Physical Medicine
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• v.10 no.1
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• pp.37-43
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• 2015

PURPOSE: The purpose of this study is to investigate the effect of the physical therapy treatment room environment using microwave diathermy on the autonomic nervous system of human body. METHODS: Participants were 24 healthy adults. Standard deviation of all normal R-R intervals(SDNN), root mean square of successive differences(RMSSD), low frequency(LF), high frequency(HF), LF/HF ratio were compared in microwave irradiation and non-irradiation group. Data were analyzed in Wilcoxon's signed-ranks test and Mann-Whitney U test. RESULTS: Standard deviation of all normal R-R intervals (SDNN), root mean square of successive differences (RMSSD), low frequency(LF), high frequency(HF), LF/HF ratio were not significantly different in microwave irradiation group. Standard deviation of all normal R-R intervals(SDNN), root mean square of successive differences (RMSSD), low frequency(LF), high frequency(HF), LF/HF ratio were not significantly different in microwave non-irradiation group. Standard deviation of all normal R-R intervals(SDNN), root mean square of successive differences (RMSSD), low frequency(LF), high frequency(HF), LF/HF ratio were not significantly different between two groups. CONCLUSION: There was no significant change in the sympathetic nervous system and parasympathetic nervous system regardless of the presence of microwave irradiation. There was no significant change in the autonomic nervous system adaptability regardless of the presence of microwave irradiation.According to this study, microwave diathermy does not have significant effect on the autonomic nervous system.Future study is necessary to investigate the long term effect of the physical therapy treatment room environment using microwave diathermy on the autonomic nervous system of the human body.

• Journal of Acupuncture Research
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• v.22 no.6
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• pp.173-180
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• 2005

Objectives : The purpose of this study was to assess the effect auricular acupuncture for acute mental stress using power spectrum analysis of the heart rate variability(HRV). Methods : 10 healthy volunteers participated in this study. After 5 minute rest, the first mental stress was provided for 5 minute. And then subjects rested for 15 minute. The second mental stress was provided for 5 minute. The acupoint, Shin-Mun point of the ear was stimulated for 15 minute. HRV was recorded before and after the first and second mental stress, and after auricular acupuncture stimulation. Results : After mental stress, normalized LF and LF/HF ratio is significantly increased. Before and after simple rest, normalized LF and normalized HF is significantly changed, but LF and LF/HF ratio is not significantly changed. On the other hand, before and after auricular acupuncture treatment, normalized LF, normalized HF is significantly changed, and also LF and LF/HF ratio is significantly decreased. Conclusion : The result suggest that auricular acupuncture can decrease more significantly in cardiac sympathetic activity due to mental stress than simple rest.

• Journal of Oriental Neuropsychiatry
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• v.20 no.1
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• pp.165-176
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• 2009

Objectives : The purpose of this study was to assess the effects of mental stress stimulation and acupucnture applied at HT7 point on heart rate variability (HRV) in normal subjects. Methods : Thirty seven healthy volunteers participated in this study. The volunteers were randomly allocated into two groups. Both groups performed a mental arithmetic stress test and stroop color-word test for 10 minute. Then, acupuncture needles were inserted on HT7 for the study group and on non-acupucnture point for the control group. HRV was recorded three times at test time and before and after acupuncture stimulation. Results : After giving mental stress stimulation to both groups, LF and LF!HF ratio were increased and HF was decreased significantly. After giving acupuncture to study group, LF and LF/HF ratio were decreased and HF was increased, but it was not significant. After giving acupuncture to control group, LF and LF/HF ratio were increased and HF was decreased, but it was not significant. Conclusions : This results show that mental arithmetic stress test and stroop color-word test contribute to activation of the sympathetic nervous system Acupuncture at HT7 could be relatively useful to decrease sympathetic activity and balance autonomic nervous system for those who are under stress.

• Journal of Pharmacopuncture
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• v.19 no.3
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• pp.207-212
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• 2016

Objectives: Acupuncture treatments are safe and effective for a wide variety of diseases involving autonomic dysregulation. Heart rate variability (HRV) is a noninvasive method for assessing sympathovagal balance. The low frequency/high frequency (LF/HF) spectral power ratio is an index of sympathovagal influence on heart rate and of cardiovascular health. This study tests the hypothesis that from rest to 30% to 50% of peak oxygen consumption, the nonlinear Conte-Zbilut-Federici (CZF) method of computing the LF/HF ratio is a more reliable index of changes in the HRV than linear methods are. Methods: The subjects of this study were 10 healthy young adults. Electrocardiogram RR intervals were measured during 6-minute periods of rest and aerobic exercise on a cycle ergometer at 30% and 50% of peak oxygen consumption ($VO_{2peak}$). Results: The frequency domain CZF computations of the LF/HF ratio and the time domain computations of the standard deviation of normal-to-normal intervals (SDNN) decreased sequentially from rest to 30% $VO_{2peak}$ (P < 0.001) to 50% $VO_{2peak}$ (P < 0.05). The SDNN and the CZF computations of the LF/HF ratio were positively correlated (Pearson's r = 0.75, P < 0.001). fast Fourier transform (FFT), autoregressive (AR) and Lomb periodogram computations of the LF/HF ratio increased only from rest to 50% $VO_{2peak}$. Conclusion: Computations of the LF/HF ratio by using the nonlinear CZF method appear to be more sensitive to changes in physical activity than computations of the LF/HF ratio by using linear methods. Future studies should determine whether the CZF computation of the LF/HF ratio improves evaluations of pharmacopuncture and other treatment modalities.

• Journal of the Korean Society of Physical Medicine
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• v.4 no.4
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• pp.241-247
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• 2009

Purpose：The purpose of this study is to investigate the effect of transcutaneous electrical stimulation on autonomic nervous system using heart rate variability analysis. Methods：31 subjects were evaluated with HRV before and after a single high-frequency TENS for 15minutes treatment. The standard deviation of all the normal RR-interval(SDNN) and lower frequency/high frequency ratio(LF/HF ratio) were recorded with TAS-9. Results：After single TENS treatment, autonomic adaptation as analyzed by SDNN was increased from $42.47\pm12.96$ to $4.43\pm16.76$(p>0.05) and autonomic balance as analyzed by LF/HF ratio was increased from $1.4\pm0.45$ to $1.45\pm0.41$(p>0.05). Conclusion：In this study, SDNN and LF/HF ratio changed in health young students as a result of single TENS treatment. But there is no significant difference between pre-treatment and post-treatment of SDNN and LF/HF ratio.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.4
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• pp.186-193
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• 2011

Purpose: This study was performed to find correlations between Edema Index and Heart Rate Variability(HRV) conducted in early postpartum period. Methods: 17 postpartum women were participated in this study which was conducted with Inbody 720(Biospace Co. Ltd.) and SA-6000(Medicore Co. Ltd.). Edema Index(Extra Cellular Water/Total Body Water) was calculated after body composition analysis and HRV result(TP, VLF, LF, HF, HF norm, LF norm, LF/HF ratio) was analysed within a week after delivery. Results: There was no significant correlations between Edema Index and HRV results in time domain analysis. also Edema Index and TP, LF, HF, LF/HF ratio have no significant correlations in frequency domain analysis. but only VLF data has significance compared with Edema Index. Conclusions: It can be suggested that VLF results analysed by HRV can be useful reference estimating postpartum edema especially occurs in early postpartum period.

• Journal of Oriental Neuropsychiatry
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• v.23 no.3
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• pp.89-98
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• 2012

Objectives : This study aims to assess the effects of incense smokes of 'Cheung-Woon'(consists of several kind of herbal powder) on autonomic nervous system activity and attention in healthy individuals. Methods : A total of 48 healthy volunteers participated in this study. The volunteers were examined with heart rate variability (HRV) before and after incense smokes inhalation of 'Cheung-Woon'. HRV measured the mean RR, mean HR, SDNN, VLF, LF, HF, TP, norm LF, norm HF, and LF/HF ratio. 'Cheung-Woon' consists of 7 herbal powders, known for useful effect on attention. Results : After inhalation smokes of 'Cheung-Woon', the mean RR, and mean HR were decreased and SDNN, VLF, LF, TP were increased, but it's not significant. Further, HF, and norm HF were decreased, and LF/HF ratio, and norm LF was increased significantly (p<0.01). Conclusions : This results (Ed note: 'this result' or 'these results') show that incense smokes inhalation of 'Cheung-Woon' is an effective way of decreasing parasympathetic nervous activity and increasing sympathetic activity and attention.