• Title/Summary/Keyword: LARS

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A Long Way from Transfer to Transition: Challenges for Pediatric and Adult Nephrologists

  • Lemke, Johanna;Pape, Lars;Oh, Jun
    • Childhood Kidney Diseases
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    • v.22 no.1
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    • pp.7-11
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    • 2018
  • Significant advances in the diagnosis and medical care of children with chronic kidney disease (CKD) are major reasons for the better survival rates of children and adolescents with CKD than the survival rates reported in previous decades. These patients are reaching adulthood, and therefore require a transition to adult medical care. This transition phase is well-recognized to be associated with considerably increased morbidities and medical problems, such as non-adherence, graft loss after transplantation, and loss to follow-up. Low adherence increases morbidity and medical complications and contributes to poorer qualities of life and an overuse of the health care system. However, these tragic outcomes may be avoidable through a structured and well-defined transition program. In the last decade, there has been increasing interest to resolve these medical and psychological problems that occur during the transfer of young adult patients from pediatric to adult renal units. The aims of a successful transition from pediatric to adult medical care include enhancing the individual development of better health-competence and stabilizing, or even improving, the state of health. This review will focus on various aspects of the transition phase of adolescents who have CKD or who underwent kidney transplantation from pediatric to adult nephrology care.

Analysis of streamflow variability on five large basin using A2 senario (A2 시나리오를 활용한 5대강수계 유출변동성 분석)

  • Jung, Il-Won;Koo, Bo-Young;Bae, Deq-Hyo
    • Proceedings of the Korea Water Resources Association Conference
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    • 2006.05a
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    • pp.1501-1505
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    • 2006
  • 본 연구에서는 국내외적으로 이슈화되고 있는 기후변화가 국내 유역에 미치는 영향을 평가하고자 하였다. 이를 위해 기상연구소에서 구축한 고해상도의 A2 기후변화 시나리오를 이용하여 국내 5대강 수계에 대해 유출시나리오를 생산하고 결과를 분석하였다. 국내 유역을 139개의 단위유역으로 구분하고 LARS-WG 모형을 적용하여 유역별 기후변화 시나리오를 생산하였다. 지역화방법을 적용하여 유역별 장기유출분석 체계를 구축하였으며, PRMS 모형을 이용하여 총 120년에 대해 유출시나리오를 생산하고 과거 30년(1971-2000년) 동안에 대해 미래 세 기간(2001-2030년, 2031-2060년, 2061-2090년)에 대한 수자원의 변동성을 분석하였다. 각 유역에서의 기준기간에 대한 유출량의 변화율은 2015s 기간에서는 $-12%\sim14%$, 2045s 기간에서는 $-23%{\sim}16%$, 2075s 기간에서는 $-14%{\sim}20%$인 것으로 나타났다. 한강권역에서는 평균적으로 5%(2015s), 0.1%(2045s), 6%(2075s)로 다소 증가될 것으로 분석되었고, 낙동강권역에서는 0.1%(2015s), -10%(2045s), -3%(2075s)로 감소하는 것으로 나타났다. 섬영과 금강도 예측기간에 대해 감소하는 것으로 나타났다.

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Assessment of Future Climate Change Impact on Soil Erosion Loss of Metropolitan Area Using Ministry of Environment Land Use Information (환경부 토지이용정보를 이용한 수도권의 미래 기후변화에 따른 토양유실 예측 및 평가)

  • Ha, Rim;Joh, Hyungkyung;Kim, Seongjoon
    • KCID journal
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    • v.21 no.1
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    • pp.89-98
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    • 2014
  • This study is to evaluate the future potential impact of climate change on soil erosion loss in a metropolitan area using Revised Universal Soil Loss Equation(RUSLE) with land use information of the Ministry of Environment and rainfall data for present and future years(30-year period). The spatial distribution map of vulnerable areas to soil erosion was prepared to provide the basis information for soil conservation and long-term land use planning. For the future climate change scenario, the MIROC3.2 HiRes A1B($CO_2720ppm$ level 2100) was downscaled for 2040-2069(2040s) and 2070-2099(2080s) using the stochastic weather generator(LARS-WG) with average rainfall data during past 30 years(1980-2010, baseline period). By applying the climate prediction to the RUSLE, the soil erosion loss was evaluated. From the results, the soil erosion loss showed a general tendency to increase with rainfall intensity. The soil loss increased up to 13.7%(55.7 ton/ha/yr) in the 2040s and 29.8%(63.6 ton/ha/yr) in the 2080s based on the baseline data(49.0 ton/ha/yr).

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Natural frequency of bottom-fixed offshore wind turbines considering pile-soil-interaction with material uncertainties and scouring depth

  • Yi, Jin-Hak;Kim, Sun-Bin;Yoon, Gil-Lim;Andersen, Lars Vabbersgaard
    • Wind and Structures
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    • v.21 no.6
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    • pp.625-639
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    • 2015
  • Monopiles have been most widely used for supporting offshore wind turbines (OWTs) in shallow water areas. However, multi-member lattice-type structures such as jackets and tripods are also considered good alternatives to monopile foundations for relatively deep water areas with depth ranging from 25-50 m owing to their technical and economic feasibility. Moreover, jacket structures have been popular in the oil and gas industry for a long time. However, several unsolved technical issues still persist in the utilization of multi-member lattice-type supporting structures for OWTs; these problems include pile-soil-interaction (PSI) effects, realization of dynamically stable designs to avoid resonances, and quick and safe installation in remote areas. In this study, the effects of PSI on the dynamic properties of bottom-fixed OWTs, including monopile-, tripod- and jacket-supported OWTs, were investigated intensively. The tower and substructure were modeled using conventional beam elements with added mass, and pile foundations were modeled with beam and nonlinear spring elements. The effects of PSI on the dynamic properties of the structure were evaluated using Monte Carlo simulation considering the load amplitude, scouring depth, and the uncertainties in soil properties.

The Impacts of Climate Change on Paddy Water Demand and Unit Duty of Water using High-Resolution Climate Scenarios (고해상도 기후시나리오를 이용한 논용수 수요량 및 단위용수량의 기후변화 영향 분석)

  • Yoo, Seung-Hwan;Choi, Jin-Yong;Lee, Sang-Hyun;Oh, Yun-Gyeong;Park, Na-Young
    • Journal of The Korean Society of Agricultural Engineers
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    • v.54 no.2
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    • pp.15-26
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    • 2012
  • For stable and sustainable crop production, understanding the effects of climate changes on agricultural water resources is necessary to minimize the negative effects which might occur due to shifting weather conditions. Although various studies have been carried out in Korea concerning changes in evapotranspiration and irrigation water requirement, the findings are still difficult to utilize fordesigning the demand and unit duty of water, which are the design criteria of irrigation systems. In this study, the impact analysis of climate changes on the paddy water demand and unit duty of water was analyzed based on the high resolution climate change scenarios (specifically under the A1B scenario) provided by the Korea Meteorological Administration. The result of the study indicated that average changes in the paddy water demand in eight irrigation districts were estimated as -2.4 % (2025s), -0.2 % (2055s), and 3.2 % (2085s). The unit duty of water was estimated to increase on an average within 2 % during paddy transplanting season and within 5 % during growing season after transplanting. This result could be utilized for irrigation system design, agricultural water resource development, and rice paddy cultivation policy-making in South Korea.

Hormone Use is Associated with Lymphovascular Invasion in Breast Cancer

  • Loof-Johanson, Margaretha;Brudin, Lars;Sundquist, Marie;Rudebeck, Carl Edvard
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1507-1512
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    • 2016
  • Background: Risk of developing breast cancer increases with short breastfeeding and the use of hormones. The prognosis of breast cancer is better if the tumours are hormone receptor positive. Since breast feeding affects estrogen and progesterone receptors, we wanted to investigate how such reproductive factors as breastfeeding and the use of hormones interact with known prognostic markers and specific tumour characteristics in women with breast cancer. Materials and Methods: A total of 250 women treated for breast cancer from a larger cohort completed a questionnaire on breastfeeding, number and age at births and use of hormones. A logistic regression analysis was made to search for connections between known prognostic markers on the one hand (type of cancer, grade, tumor size, estrogen receptor and progesterone receptor, lymphovascular invasion and DNA-ploidy) and reproductive data, breastfeeding, and hormone use on the other. Results and Conclusions: Hormone use, but not breastfeeding, was significantly associated, also on multivariate analysis, with the prognostic variable lymphovascular invasion, connected to a worse prognosis. No other hormone use or breast feeding correlations with prognostic variables were found.

On Thermal and State-of-Charge Balancing using Cascaded Multi-level Converters

  • Altaf, Faisal;Johannesson, Lars;Egardt, Bo
    • Journal of Power Electronics
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    • v.13 no.4
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    • pp.569-583
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    • 2013
  • In this study, the simultaneous use of a multi-level converter (MLC) as a DC-motor drive and as an active battery cell balancer is investigated. MLCs allow each battery cell in a battery pack to be independently switched on and off, thereby enabling the potential non-uniform use of battery cells. By exploiting this property and the brake regeneration phases in the drive cycle, MLCs can balance both the state of charge (SoC) and temperature differences between cells, which are two known causes of battery wear, even without reciprocating the coolant flow inside the pack. The optimal control policy (OP) that considers both battery pack temperature and SoC dynamics is studied in detail based on the assumption that information on the state of each cell, the schedule of reciprocating air flow and the future driving profile are perfectly known. Results show that OP provides significant reductions in temperature and in SoC deviations compared with the uniform use of all cells even with uni-directional coolant flow. Thus, reciprocating coolant flow is a redundant function for a MLC-based cell balancer. A specific contribution of this paper is the derivation of a state-space electro-thermal model of a battery submodule for both uni-directional and reciprocating coolant flows under the switching action of MLC, resulting in OP being derived by the solution of a convex optimization problem.

KINETICS OF POLYELECTROLYTE ADSORPTION ON CELLULOSIC FIBRES

  • Lars Wagberg;Sjolund, Anna-Karin
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 1999.11b
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    • pp.34-42
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    • 1999
  • The present investigation has focused up on the study of the adsorption of three different molecular mass fractions of a polyDiMethylDiAllylAmmoniumChloride (DMDAAC) (8750(LM\ulcorner), 48000(MM\ulcorner) and 1200000(HM\ulcorner)) on bleached chemical fibres. Both kinetics of adsorption and equilibrium adsorption measurements have been conducted and each adsorption has been measured by polyelectrolyte titration. The results show that the LM\ulcorner polymer can reach all of the charges in the fibre wall whereas the MM\ulcorner and HM\ulcorner can only reach the external surfaces of the fibres. It is also shown that the kinetics of adsorption of the LMw polymer is not at all affected by the presence of a saturated layer of HMw polymer on the surface of the fibres. Finally, the results from the investigation show that it is possible to have full coverage of the external surface of the fibres by a high molecular mass polymer and a full coverage of the internal surface of the fibres with a low molecular mass polymer. This is true if the high molecular masspolymer is added first followed by addition of the low molecular masspolymer.

Climate Change Impacts Assessments on Water Resources at 5 Large River Basin with High Resolution Scenario (고해상도 시나리오를 활용한 5대강수계 수자원 영향평가)

  • Bae, Deg-Hyo;Jung, Il-Won;Jun, Tae-Hyun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.286-290
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    • 2007
  • 기후변화가 국내 수자원에 미치는 영향을 평가하기 위해 고해상도 기후변화 시나리오를 이용하여 수자원의 변동성을 평가하였다. IPCC SRES A2 시나리오를 이용하여 5대강수계 139개 유역에 대해 기후 및 유출시나리오를 생산하고 수자원의 변동성을 시공간적으로 분석하였다. 고해상도$(27km{\times}27km)$ 시나리오는 기상연구소에서 전구기후모델인 ECHO-G의 결과를 지역기후모델인 MM5에 경계조건을 사용하여 역학적으로 상세화한 것이다. 이 시나리오를 이용하여 현실성 있는 유역별 기후시나리오를 생산하기 위해 LARS-WG를 사용하였으며, 유출시나리오 생산을 위해 USGS에서 개발된 PRMS 모형을 이용하였다. 생산된 시나리오를 이용하여 분석한 결과 전반적으로 한강유역이 위치한 북쪽유역에서는 연평균유출량이 증가되고, 남쪽에 위치한 유역들에서는 감소할 것으로 전망되었다. 이것은 기온의 증가에 따른 평균증발산량의 증가에 따른 영향으로 나타났다. 계절별로는 봄과 여름철의 유출량은 감소하고, 가을과 겨울철 유출량은 증가할 것으로 분석되었다. 그러나 여름철 평균유출량의 감소에도 불구하고 고수량(Q>100mm)의 규모 및 빈도가 증가할 것으로 전망되었다.

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