• KSBB Journal
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• v.17 no.6
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• pp.566-570
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• 2002

In lactic acid fermentation, the end product inhibition by lactic acid causes several problems. The most important of which are low lactate formation rate and its recovery from fermentation broth. To overcome these problems, extractive lactic acid fermentation was carried out in a bioreactor, which was connected to a column packed with anion exchange resin (Amberlite IRA-400, 250 g). The system was started as a batch process, and then the separation process was started when the lactic acid concentration reached 10 g/L, 20 g/L or 30 g/L. In each case, total lactic acid concentration was reached to 48.6, 53.6, 52.6 g/L with its productivity of 1.2 g/L $.$ h, 1.6 g/L $.$ h, and 1.3 g/L $.$ h, respectively Especially, in the case of the 20 g/L recycling-initiation process, extractive fermentation reduced tie fermentation time (17 hrs) by 34% in comparison with the conventional batch process. The direct consequence of this time reduction was shown by a 1.8 fold increase in overall lactic acid productivity.

• Journal of the Korean Mathematical Society
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• v.55 no.3
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• pp.671-694
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• 2018

In this paper, we investigate the weighted vector-valued bounds for a class of multilinear singular integral operators, and its commutators, from $L^{p_1}(l^{q_1};\;{\mathbb{R}}^n,\;w_1){\times}{\cdots}{\times}L^{p_m}(l^{q_m};\;{\mathbb{R}}^n,\;w_m)$ to $L^p(l^q;\;{\mathbb{R}}^n,\;{\nu}_{\vec{w}})$, with $p_1,{\cdots},p_m$, $q_1,{\cdots},q_m{\in}(1,\;{\infty})$, $1/p=1/p_1+{\cdots}+1/p_m$, $1/q=1/q_1+{\cdots}+1/q_m$ and ${\vec{w}}=(w_1,{\cdots},w_m)$ a multiple $A_{\vec{P}}$ weights. Our argument also leads to the weighted weak type endpoint estimates for the commutators. As applications, we obtain some new weighted estimates for the $Calder{\acute{o}}n$ commutator.

• The Korean Journal of Food & Health Convergence
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• v.6 no.1
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• pp.9-15
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• 2020

Salinity with sodic condition disturbs germination, retards emergence, and slow down seedling development of Lemon Grass (Cymbopogon citratus).Lemongrass is a perennial grass plant widely distributed worldwide and most especially in tropical and subtropical countries. This research experiment was designed to evaluate the influences of (4 dSm^-1+ 13.5 (mmol L^-1)^-1/2, 5 dSm^-1+ 25 (mmol L^-1)^1/2, 5 dSm^-1+ 30 (mmol L^-1)^1/2, 10 dSm^-1+ 25 (mmol L^-1)^1/2 and 10 dSm^-1+ 30 (mmol L^-1)^1/2) on biomass produce of lemon grass against salt tolerance. The uppermost biomass yield (45.53 gpot^-1) was produced by 4 dSm^-1+ 13.5 (mmol L^-1)^1/2 treatment. The increase in the intensity of salts reduced the growth of lemon grass. Lower biomass yield (79.33 gpot^-1) was gained at 10 dSm^-1+ 30 (mmol L^-1)^1/2. 5 dSm^-1+ 25 (mmol L^-1)^1/2 treatment performed enhanced outcome i.e. the least reduction % over control (5.87). Salinity- sodicity showed serious effect on the growth reduction from 5.87% to33.60%. This reduction gap was affected by the negative effect of salinity and sodicity on Linseed growth. Salinity- sodicity showed severe impact on the growth reduction from 5.87% to33.60%. Based on the findings, lemon Grass (Cymbopogon citratus).was capable to grow up the maximum at 4 dSm^-1+ 13.5 (mmol L^-1)^1/2 treatment.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.39 no.6
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• pp.537-541
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• 1994

This study was conducted to investigate the possibility of callus induction and plant regeneration from immature inflorescence, stem and petiole of A. koreana MAX. which is worth enough to be used as food and medicine. The callus induction and its proliferation was best when immature inflorescence segments were placed on MS medium supplemented with 2, 4-D 2mg / l. The white and compact embryogenic callus on the surface of dark yellow and soft callus which was induced from immature inflorescence segments came into being only on MS medium with 2, 4-D 1mg /l and 2mg /l, but didn't come into being on the other ones. The shoot came into being effectively from callus derived from immature inflorescence on MS medium mixed 2, 4-D 0. 1mg /l with Kinetin 1mg /l, and 2, 4-D 0.5mg /1 with Kinetin 2mg /l. Immature inflorescence was most appropriate material for callus induction and plant regeneration.

• Korean Journal of Plant Tissue Culture
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• v.21 no.2
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• pp.117-121
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• 1994

The optimal level of growth regulator for callus initiation stem explants was BAP 0.1mg/L combined with 2,4-D 1.0 mg/L in Murashige and Skoog (MS) medium supplemented with 30g/L sucrose and 10g/L agar, and that for cell growth was BAP 0.1+2,4-D 0.5 mg/L in MS liquid medium. The regeneration frequency of P. oleracea cells was significantly increased by subjecting the cells to dessication for 1and 2 h up to 83%, respectively, as compared with untreated control showing 61%. Cell viability and survival rate was inhibited by pretreatment of 0.6% NaCl for 2 days, while regeneration ability was not affected by the treatment. Pretreatment of 100g/L sucrose for 2 days markedly stimulated the regeneration of cells up to 81%. These results suggest that in addition to physiological changes, water stress resulted from dessication and high concentration of sucrose and NaCl is closely related to the regeneration of P. oleracea cultured cells.

• The Korea Journal of Herbology
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• v.31 no.4
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• pp.53-60
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• 2016

Objective : The purpose of this study was to investigate anti-aging and antioxidant effects of extracts of Nelumbo nucifera leaves (NN-L) using ethanol on skin .Methods : Each part of leaves(NN-L), flowers(NN-F) and stem(NN-S) was extracted with 70% ethanol. We performed radical scavenging assay(DPPH, ABTS+, Superoxide anion radical), elastase inhibition assay, collagenase inhibition assay. NN-L extracts were tested for cell viability(MTT assay), MMP-1 inhibition and MMP-1 protein expression on CCD-986sk cells (human fibroblast line).Results : Recently, many studies have reported that elastin is also involved in inhibiting or repairing wrinkle formation, although collagen is a major factor in the skin wrinkle formation. We measured its free radical scavenging activity, elastase inhibitory activity and expression of MMP-1 (matrix metalloprotease-1) in human fibroblast cells. Among the parts of Nelumbo nucifera, NN-L showed the highest antioxidant activities and in radical scavenging. DPPH, ABTS+ and Superoxide anion radical scavenging activity of NN-L at concentration of 1,000 μg/mL were 91.43%, 99.31% and 73.7% respectively. In vitro elastase and collagenase inhibition effects of NN-L at concentration of 1,000 μg/mL was 42.8% and 55.3% respectively. The ethanol extract of NN-L showed cell viability of 95.4% in 50 μg/mL concentration. In addition, The results from Western blot assay showed that NN-L decreased the expression of MMP-1 protein in a dose-dependent manner (by up to 35.0% at 50 μM).Conclusion : The findings suggest that the NN-L great potential as a cosmeceutical ingredient with antioxidant and anti-wrinkling effects.

• Korean Journal of Materials Research
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• v.9 no.8
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• pp.849-853
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• 1999

In the study, superconducting properties of $Bi_2$-x(sub)$LSr_2$Ca(sub)1+x(sub)$LCu_2$O(sub)8+d (x(sub)L=0, 0.05, 0.1, 0.2) films prepared by the LPE method was investigated. The peak decompositions of Sr3d and Ca2p XPS spectra, together with the EPMA results, elucidated the occupancies of Bi, Sr and Ca atoms on the SrO- and Ca-layers. The lattice parameter c monotonically increased with increasing x(sub)L for $0\leq$x(sub)L$\leq$0.2. The superconducting critical temperature T(sub)c showed a maximum value around x(sub)L=0.1. The x(sub)L dependence of the superconducting critical temperature T(sub)c and the lattice parameter c are explained by the changes of the excess oxygens in the BiO-layer. Since distribution and deficiency of the atoms in SrO-layer have influenced on superconducting properties and crystal structure.

• Korean Journal of Plant Resources
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• v.21 no.5
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• pp.357-361
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• 2008

The photosynthetic characteristics of three Ligularia species, L. fischeri, L. fischeri var. spiciformis and L. stenocephala under-tree cultivated in Dunnae-myeon, Hoengsung-gun were measured and compared. Total mean photosynthetic rate increased with increasing the light intensity up to 2,000 PPFD. Mean photosynthetic rate of L. fischeri increased to maximum value of $21.1{\mu}mol\;CO_{2}m^{-2}s^{-1}$ with increasing the light intensity up to 1,600 PPFD, but it was decreased at 2,000 PPFD. The highest photosynthetic rate was shown in L. fischeri var. spiciformis, followed by L. fischeri, and L. stenocephala. was the highest $27.39{\mu}mol\;CO_{2}m^{-2}s^{-1}$ among three species, followed by that of The differences in photosynthetic rates were significantly different among the species each measuring date. L. fischeri var. spiciformis was more adaptive species at the low elevated under-tree cultivated sites, such as, Sanchemaeul Dunnae-myeon Hoeyngseung-gun than L. fischeri and L. stenocephala.

• Journal of the Korean Chemical Society
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• v.32 no.1
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• pp.60-64
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• 1988

Synthesis and biological activity test are described for the (Z)-11-hexadecen-1-ol, (Z)-11-hexadecen-1-yl acetate, and (Z)-11-hexadecen-l-al, the sex pheromone of the diamond back moth, Plutella xylostella L.. Lithium acetylide was alkylated with 10-bromodecan-1-ol THP ether to give 11-hexadecyn-l-ol THP ether. 11-Hexadecyn-l-ol THP ether was stereoselectively reduced over Pd/BaSO4to yield (Z)-11-hexadecen-l-ol THP ether, which was in turn deprotected to provide (Z)-11-hexadecen-l-ol. (Z)-11-Hexadecen-l-ol was acetylated and oxidized to afford (Z)-11-hexadecen-1-yl acetate and (Z)-11-hexadecen-l-al, respectively. Biological activity test of the synthetic compounds, (Z)-11-hexadecen-l-ol, (Z)-11-hexadecen-1-yl acetate, and (Z)-11-hexadecen-l-al in the ratio of 0.1 : 5 : 5 was tested in the field using polyethylene capsules as containers. The numbers of moth trapped with pheromone vials were counted.

• Biomedical Science Letters
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• v.27 no.2
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• pp.95-98
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• 2021

The S100 family proteins act as inducers of cancer cell apoptosis and inflammatory mediators. This study examined the pro-apoptotic mechanism caused by S100A8 and S100A9 in human FIP1L1-PDGFRα-positive eosinophilic leukemia cells. S100A8 and S100A9 elicited the death of EoL-1 cells in a time and dose-dependent manner. The activation of PDGFRα was suppressed by a decrease in PDGFRα after treatment with S100A8 and S100A9. Cycloheximide, a translation inhibitor, suppressed PDGFRα expression from 1 h to 5 h, and a co-treatment with S100A8 and S100A9 boosted the decrease in expression. The phosphorylation and expression of STAT5 decreased after treatment with S100A8 and S100A9 in EoL-1 and imatinib-resistant (EoL-1-IR) cells. S100A8 and S100A9 induced the chemotaxis of EoL-1 cells but did not affect the chemoattraction of EoL-1-IR. These findings indicate the cell death mechanism due to S100 family proteins and the development of leukemia therapy using S100A8 and S100A9.