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Understanding G.A.R.L.I.C.s.: An Innopreneurship Platform for Smart Cities

  • Narasimhalu, Arcot Desai
    • World Technopolis Review
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    • v.8 no.1
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    • pp.8-20
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    • 2019
  • The intent of this paper is to identify key actors of a sustainable Smart City and define metrics that will allow assessment and better management of Sustainable Smart Cities. The paper is organized in two major segments. The first segment reviews the definition, six components, six action items of Smart Cities. It describes briefly a sample Smart City project and presents a selection of different dimensions along which Smart Cities are ranked and the rankings. The segment also discusses the technology architecture of a Smart City and then examines the definition and components of an innovation platform. The second presents the original contributions of the paper. It first introduces the dynamics created seven key actors of a Smart City ecosystem and describes their existing and potential contributions. It then defines Innopreneurship platform and presents a triple bottom line based quality metric to evaluate such a platform. This segment also discusses reengineering an economy and suggests a Smart City's Innovation Platform Score. The actions to be taken by the key actors of a Smart City in order to make it a Sustainable Smart City are described in several subsections. We hope these concepts and metrics will be a good starting point and will be refined over time by others.

Effects of Growth Regulators and Explants on Direct Somatic Embryogenesis in Liquid Culture of Rehmannia glutinosa (지황의 액체배양에서 식물생장조정제와 치상 조직이 직접 체세포배 형성에 미치는 영향)

  • Park, Ju-Hyun;Chae, Young-Am
    • Korean Journal of Medicinal Crop Science
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    • v.5 no.4
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    • pp.289-293
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    • 1997
  • The effects of plant regulators on direct somatic embryogenesis in liquid culture of Rehmannia glutinosa were investigated and the proper explant for direct somatic embryo formation was studied. Direct somatic embryos were induced from leaf segments culture in the MS liquid medium containing 0.5 mg/l of both IAA and NAA, while IBA of 1.0 mg/l was required for the same effect. Many somatic embryos were directly formed at the concentration of 2.0 mg/l cytokinin such as BA, kinetin and zeatin, but somatic embryogenesis was relatively poor at above or below this level. Relatively more somatic embryos were induced in the combination of 1.0mg/l IAA and 2.0mg/l zeatin. Formation of somatic embryos begun after 6 weeks on stem segments, while 7 weeks both on petiole and leaf. However, overall production of somatic embryos after 8 weeks was higher in leaf segment than that of stem segment.

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Automatic Speech Recognition Research at Fujitsu (후지쯔에 있어서의 음성 자동인식의 현상과 장래)

  • Nara, Yasuhiro;Kimura, Shinta;Loken-Kim, K.H.
    • The Journal of the Acoustical Society of Korea
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    • v.10 no.1
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    • pp.82-91
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    • 1991
  • The history of automatic speech recognition research, and current and future speech products at Fujitsu are introduced here. The speech recognition research at Fujitsu started in 1970. Our research efforts have results in the production of a speaker dependent 12,000 word discrete / connected word recognizer(F2360), and a speaker independent 17 word discrete word recognizer(F2355L/S). Currently, we are working on a larger vocabulary speech recognizer, in which an input utterance will be matched with networks representing possible phonemic variations. Its application to text input is also discussed.

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A Polymeric Micellar Carrier for the Solubilization of Biphenyl Dimethyl Dicarboxylate

  • Chi, Sang-Cheol;Yeom, Dae-Il;Kim, Sung-Chul;Park, Eun-Seok
    • Archives of Pharmacal Research
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    • v.26 no.2
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    • pp.173-181
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    • 2003
  • A polymeric micelle drug delivery system was developed to enhance the solubility of poorly-water soluble drug, biphenyl dimethyl dicarboxylate, DDB. The block copolymers consisting of poly(D,L-lactide) (PLA) as the hydrophobic segment and methoxy poly(ethylene glycol) (mPEG) as the hydrophilic segment were synthesized and characterized by NMR, DSC and MALDI-TOF mass spectroscopy. The size of the polymeric micelles measured by dynamic light scattering showed a narrow monodisperse size distribution with the average diameter less than 50 nm. The MW of mPEG-PLA, 3000 (MW of mPEG, 2 K; MW of PLA, 1K), and the presence of hydrophilic and hydrophobic segments on the polymeric micelles were confirmed by MALDI-TOF mass spectroscopy and NMR, respectively. Polymeric micelle solutions of DDB were prepared by three different methods, i.e. the matrix method, emulsion method and dialysis method. In the matrix method, DDB solubility was reached to 13.29 mg/mL. The mPEG-PLA 2K-1K micelle system was compared with the poloxamer 407 micelle system for their critical micelle concentration, micelle size, solubilizing capacity, stability in dilution and physical state. DDB loaded-polymeric micelles prepared by the matrix method showed a significantly increased aqueous solubility (>5000 fold over intrinsic solubility) and were found to be superior to the poloxamer 407 micelles as a drug carrier.

Characterization of the Putative Membrane Fusion Peptides in the Envelope Proteins of Human Hepatitis B Virus

  • Kang, Ha-Tan;Yu, Yeon-Gyu
    • Bulletin of the Korean Chemical Society
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    • v.28 no.10
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    • pp.1756-1762
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    • 2007
  • Envelope proteins of virus contain a segment of hydrophobic amino acids, called as fusion peptide, which triggers membrane fusion by insertion into membrane and perturbation of lipid bilayer structure. Potential fusion peptide sequences have been identified in the middle of L or M proteins or at the N-terminus of S protein in the envelope of human hepatitis B virus (HBV). Two 16-mer peptides representing the N-terminal fusion peptide of the S protein and the internal fusion peptide in L protein were synthesized, and their membrane disrupting activities were characterized. The internal fusion peptide in L protein showed higher activity of liposome leakage and hemolysis of human red blood cells than the N-terminal fusion peptide of S protein. Also, the membrane disrupting activity of the extracellular domain of L protein significantly increased when the internal fusion peptide region was exposed to N-terminus by the treatment of V8 protease. These results indicate that the internal fusion peptide region of L protein could activate membrane fusion when it is exposed by proteolysis.

The Interlanguage Speech Intelligibility Benefit for Listeners (ISIB-L): The Case of English Liquids

  • Lee, Joo-Kyeong;Xue, Xiaojiao
    • Phonetics and Speech Sciences
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    • v.3 no.1
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    • pp.51-65
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    • 2011
  • This study attempts to investigate the interlanguage speech intelligibility benefit for listeners (ISIB-L), examining Chinese talkers' production of English liquids and its perception of native listeners and non-native Chinese and Korean listeners. An Accent Judgment Task was conducted to measure non-native talkers' and listeners' phonological proficiency, and two levels of proficiency groups (high and low) participated in the experiment. The English liquids /l/ and /r/ produced by Chinese talkers were considered in terms of positions (syllable initial and final), contexts (segment, word and sentence) and lexical density (minimal vs. nonminimal pair) to see if these factors play a role in ISIIB-L. Results showed that both matched and mismatched interlanguage speech intelligibility benefit for listeners occurred except for the initial /l/. Non-native Chinese and Korean listeners, though only with high proficiency, were more accurate at identifying initial /r/, final /l/ and final /r/, but initial /l/ was significantly more intelligible to native listeners than non-native listeners. There was evidence of contextual and lexical density effects on ISIB-L. No ISIB-L was demonstrated in sentence context, but both matched and mismatched ISIB-L was observed in word context; this finding held true for only high proficiency listeners. Listeners recognized the targets better in the non-minimal pair (sparse density) environment than the minimal pair (higher density) environment. These findings suggest that ISIB-L for English liquids is influenced by talkers' and listeners' proficiency, syllable position in association with L1 and L2 phonological structure, context, and word neighborhood density.

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Based on morphology and molecular data, Palisada rigida comb. nov. and Laurencia decussata comb. et stat. nov. (Rhodophyta, Rhodomelaceae) are proposed

  • Metti, Yola
    • ALGAE
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    • v.37 no.1
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    • pp.15-32
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    • 2022
  • Inspecting herbaria collections of Laurencia rigida highlighted frequent misidentifications between L. rigida and L. heteroclada f. decussata, two poorly studied taxa from Australia. Recent collections of DNA material, including from topotype material, allowed for re-examination of these two taxa using molecular techniques. Detailed morphological and molecular analyses based on two markers (rbcL and COI-5P) strongly supported these two taxa as being distinct from each other and requiring nomenclatural changes. Comprehensive morphological analyses highlighted features useful for accurate identifications. Interestingly, L. rigida was found to belong to the genus Palisada with evidence from both the morphology and molecular data. Therefore, this study proposed recognizing L. rigida as Palisada rigida comb. nov. Molecular data for L. heteroclada f. decussata on the other hand supported its separation from L. heteroclada, with too great a molecular distance to be considered a variety. Morphological characters that best separated P. rigida from L. decussata included seven characters; number of pericentral cells per vegetative axial segment, the presence of secondary pit connections, the presence of lenticular thickenings, tetrasporangia alignment, the presence of corps en cerise, holdfast morphology, and overall plant shape. Morphologically, L. heteroclada f. decussata was also separated from L. heteroclada, particularly by the following characteristics; ultimate branchlets morphologies, lower order branch lengths, primary axis and holdfast morphologies. Therefore, it was proposed that L. heteroclada f. decussata is recognized at a species level as L. decussata comb. et stat. nov.

Mechanical Property of Segmented Block Copolyetherester Effected by Changing the Hard Segment(II) (하드 세그멘트 구조 변화가 세그멘트화 블록 코폴리에테르에스테르의 기계적 성질에 미치는 효과(II))

  • Kim, Hae-Young;Jang, Kyung-Ho;Baik, Doo-Hyun
    • Proceedings of the Korean Fiber Society Conference
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    • 2003.04a
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    • pp.329-330
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    • 2003
  • In general, the thermoplastic elastomers have the elastic recovery property caused by phyical crosslinks after the stress is applied. Segmented block copolyetheresters also have been used as elastomers. Many$\^$l-2/ tried to improve the elastic recovery of those which are less elastic than polyurethane. We confirmed that the copolyetherester based on poly(2,6-butylene naphthalate)(PBN) ha.4 segment had the high melting temperature, whcih was useable at the broader temperature range and the one based on poly(1,3-trimethylene terephthalate)(PTT) the high crystallinity, which would be expected to get the high elastic recovery. (omitted)

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EFFECT OF NERVE GROWTH FACTOR IN REGENERATION OF MANDIBULAR NERVE OF RABBIT (가토 하치조신경 재생에 있어 Nerve Growth Factor의 효과)

  • Park, Kwang;Kim, Hyun-Tae;Lee, Jong-Ho
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.18 no.2
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    • pp.261-268
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    • 1996
  • An experimental study was performed to evaluate the efficacy of nerve growth factor(NGF) on inferior alveolar nerve in a rabbit model. In 20 New Zealand white rabbits, 14mm of bilat eral alveolar nerve were resected and the defects were repaired with the 17mm silicone conduits. In group I, 5mm autologous nerve segment were located centrally in the left side after tubulization and NGF solution(Sigma chemical 0.1 mg/mL) was instilled into each conduit. In group II, nerve repair modality was the same but no NGF solution was instilled into the conduits. On 2 months and 6 months postoperatively, the results were evaluated by clinical and hist omorphometric assessment. The result was that autologous nerve segment group show the best nerve regeneration effect and NGF instilled group the worst.

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Strength and Crack Growth Computation for Various types of Stringers for Stiffened Panels using XFEM Techniques

  • Krishna, Lok S;Reshma, G;Dattaguru, B
    • International Journal of Aerospace System Engineering
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    • v.7 no.1
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    • pp.7-15
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    • 2020
  • In this paper the crack growth, modeling, and simulation of the stiffened and un-stiffened cracked panels presented using commercially available finite element software packages. Computation of stresses and convergence of stress intensity factor for single edge notch (SEN) specimens carried out using the finite element method (FEM) and extended finite element method (XFEM) and compared with an analytical solution. XFEM techniques like cohesive segment method and LEFM using virtual crack closure technique (VCCT), used for crack growth analysis and presented results for un-stiffened and stiffened panels considering various crack domain. The non-linear analysis considering both geometric and material non-linearity on stiffened panels with various stringers like a blade, L, inverted T and Z sections the results were presented. Arrived at the optimum stringer section type for the considered panel under axial loading from the numerical analysis.