• Title/Summary/Keyword: Kyung-Hee

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23-hydroxyursolic acid Induces Apoptosis of human leukemia HL-60 cells

  • Heon, Won-Jong;Shin, kyung-Min;Rim, Seo-Bo;Park, Hee-Jun;Park, Jong-Won;Lee, Kyung-Tae
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.318.1-318.1
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    • 2002

  • We found that 23-hydroxyursolic acid, triterpenoid was isolated from Cussonia bancoensis have a significant cytotoxic activity against HL -60 human promyelocytic leukemia cells. The IC of 23-hydroxyursolic acid was 32.83 $\mu$M. These anti-proliferative activity was due to induction of apoptosis. The effect of apoptosis was identified by DNA laddering, DAPI assay. PI staining, and Annerxin V-FITC binding assay. (omitted)

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A Case Report of an Ataxia Patient with Sensory Loss Diagnosed with Thalamic Infarction (감각장애를 동반한 Thalamic Ataxia 환자 치험 1례)

  • Lee, Bo-Yun;Lee, Hyun-Joong;Lee, Dong-Hyuk;Doo, Kyung-Hee;Kim, Soo-Kyung;Cho, Seung-Yeon;Park, Jung-Mi;Ko, Chang-Nam;Bae, Hyung-Sup;Park, Seong-Uk
    • The Journal of the Society of Stroke on Korean Medicine
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    • v.15 no.1
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    • pp.39-49
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    • 2014

  • This report is about a case of an ataxia patient with sensory loss diagnosed with thalamic Infarction. The patient had symtoms of gait disturbances and dysmetria. We used Korean medicine treatment modalities including acupunture, electroacupuncture, moxibustion and herb medicines. The improvement of ataxia was evaluated by International Cooperative Ataxia Rating Scale and Balance masterⓇ system. After treatment, decreased scores of International Cooperative Ataxia Rating Scale and change of the trace of Balance masterⓇ system showed that symtoms of ataxia were improved. Sensory deficits and other conditions were also getting better. This report suggests that Korean medicine could have a therapeutic effect for Thalamic ataxia.

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