• Animal Bioscience
• /
• v.37 no.1
• /
• pp.1-15
• /
• 2024

Poultry coccidiosis is an intestinal infection caused by an intracellular parasitic protozoan of the genus Eimeria. Coccidia-induced gastrointestinal inflammation results in large economic losses, hence finding methods to decrease its prevalence is critical for industry participants and academic researchers. It has been demonstrated that coccidiosis can be effectively controlled and managed by employing anticoccidial chemical compounds. However, as a result of their extensive use, anticoccidial drug resistance in Eimeria species has raised concerns. Phytochemical/herbal medicines (Artemisia annua, Bidens pilosa, and garlic) seem to be a promising strategy for preventing coccidiosis, in accordance with the "anticoccidial chemical-free" standards. The impact of herbal supplements on poultry coccidiosis is based on the reduction of oocyst output by preventing the proliferation and growth of Eimeria species in chicken gastrointestinal tissues and lowering intestinal permeability via increased epithelial turnover. This review provides a thorough up-to-date assessment of the state of the art and technologies in the prevention and treatment of coccidiosis in chickens, including the most used phytochemical medications, their mode of action, and the applicable legal framework in the European Union.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.8 no.3
• /
• pp.1144-1156
• /
• 2014

In Internet, IP multicast has been used successfully to provide an efficient, best-effort delivery service for group communication applications. However, applications such as multiparty private conference, distribution of stock market information, pay per view and other subscriber services may require secure multicast to protect integrity and confidentiality of the group traffic, and validate message authenticity. Providing secure multicast for group communication is problematic without a robust group key management. In this paper, we propose a group key management scheme based on the secret sharing technology to require each member by itself to generate the group key when receiving a rekeying message multicast by the group key distributor. The proposed scheme enforces mutual authentication between a member and the group key distributor while executing the rekeying process, and provides forward secrecy and backward secrecy properties, and resists replay attack, impersonating attack, group key disclosing attack and malicious insider attack.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.11
• /
• pp.4423-4428
• /
• 2014

A novel monoclonal antibody (mAb), known as AC10364, was identified from an antibody library generated by immunization of mice with human carcinoma cells. The mAb recognized proteins in lysates from multiple carcinoma cell lines. Cell cytotoxicity assays showed that AC10364 significantly inhibited cell growth and induced apoptosis in multiple carcinoma cell lines, including Bel/fu, KATO-III and A2780. Compared with mAb AC10364 or chemotherapeutic drugs alone, the combination of mAb AC10364 with chemotherapeutic drugs demonstrated enhanced growth inhibitory effects on carcinoma cells. These results suggest that mAb AC10364 is a promising candidate for cancer therapy.

• Structural Engineering and Mechanics
• /
• v.60 no.3
• /
• pp.387-404
• /
• 2016

In this paper, the response and failure of sharp-notched 6061-T6 aluminum alloy circular tubes with five different notch depths of 0.4, 0.8, 1.2, 1.6 and 2.0 mm subjected to cyclic bending were experimentally and theoretically investigated. The experimental moment-curvature relationship exhibits an almost steady loop from the beginning of the first cycle. And, the notch depth has almost no influence on its relationship. However, the ovalization-curvature relationship exhibits a symmetrical, increasing, and ratcheting behavior as the number of cycles increases. In addition, a higher notch depth of a tube leads to a more severe unsymmetrical trend of the ovalization-curvature relationship. Focusing on the aforementioned relationships, the finite element software ANSYS was used to continue the related theoretical simulation. Furthermore, the five groups of tubes tested have different notch depths, from which five unparallel straight lines can be observed from the relationship between the controlled curvature and the number of cycles required to produce failure in the log-log scale. Finally, a failure model was proposed to simulate the aforementioned relationship. Through comparison with the experimental data, the proposed model can properly simulate the experimental data.

• Journal of The Korean Astronomical Society
• /
• v.37 no.5
• /
• pp.597-600
• /
• 2004

A substantial number of processes have been suggested as possible contributors to the extragalactic $\gamma$-ray background (EGRB). Yet another contribution to this background will be emission produced in hadronic interactions of cosmic-ray protons with the cluster thermal gas; this class of cosmic rays (CRs) has been shown to be responsible for the EUV emission in the Coma Cluster of galaxies. In this paper we assume the CRs in the Coma Cluster is prototypic of all clusters and derive the contribution to the EGRB from all clusters over time. We examine two different possibilities for the scaling of the CR flux with cluster size: the number density of the CRs scale with the number density of the thermal plasma, and alternatively, the energy density of the CRs scale with the energy density of the plasma. We find that in all scenarios the EGRB produced by this process is sufficiently low that it will not be observable in comparison with other mechanisms that are likely to produce an EGRB.

• Mycobiology
• /
• v.42 no.3
• /
• pp.241-248
• /
• 2014

NADPH oxidases (Noxes), transmembrane proteins found in most eukaryotic species, generate reactive oxygen species and are thereby involved in essential biological processes. However, the fact that genes encoding ferric reductases and ferric-chelate reductases share high sequence similarities and domains with Nox genes represents a challenge for bioinformatic approaches used to identify Nox-encoding genes. Further, most studies on fungal Nox genes have focused mainly on functionality, rather than sequence properties, and consequently clear differentiation among the various Nox isoforms has not been achieved. We conducted an extensive sequence analysis to identify putative Nox genes among 34 eukaryotes, including 28 fungal genomes and one Oomycota genome. Analyses were performed with respect to phylogeny, transmembrane helices, di-histidine distance and glycosylation. Our analyses indicate that the sequence properties of fungal Nox genes are different from those of human and plant Nox genes, thus providing novel insight that will enable more accurate identification and characterization of fungal Nox genes.

• Biomolecules & Therapeutics
• /
• v.25 no.5
• /
• pp.471-481
• /
• 2017

The canonical transient receptor potential channels (TRPCs) constitute a series of nonselective cation channels with variable degrees of $Ca^{2+}$ selectivity. TRPCs consist of seven mammalian members, TRPC1, TRPC2, TRPC3, TRPC4, TRPC5, TRPC6, and TRPC7, which are further divided into four subtypes, TRPC1, TRPC2, TRPC4/5, and TRPC3/6/7. These channels take charge of various essential cell functions such as contraction, relaxation, proliferation, and dysfunction. This review, organized into seven main sections, will provide an overview of current knowledge about the underlying pathogenesis of TRPCs in cardio/cerebro-vascular diseases, including hypertension, pulmonary arterial hypertension, cardiac hypertrophy, atherosclerosis, arrhythmia, and cerebrovascular ischemia reperfusion injury. Collectively, TRPCs could become a group of drug targets with important physiological functions for the therapy of human cardio/cerebro-vascular diseases.

• Structural Engineering and Mechanics
• /
• v.28 no.5
• /
• pp.495-514
• /
• 2008

In this paper, experimental and theoretical investigations of the effect of the mean moment on the response and collapse of circular thin-walled tubes subjected to cyclic bending are discussed. To highlight the influence of the mean moment effect, three different moment ratios r (minimum moment/ maximum moment) of -1, -0.5 and 0, respectively, were experimentally investigated. It has been found that the moment-curvature loop gradually shrinks with the number of cycles, and becomes stable after a few cycles for symmetric cyclic bending (r = -1). However, the moment-curvature loop exhibits ratcheting and increases with the number of cycles for unsymmetric cyclic bending (r = -0.5 or 0). In addition, although the three groups of tested specimens had three different moment ratios, when plotted in a log-log scale, three parallel straight lines describe the relationship between the controlled moment range and the number of cycles necessary to produce buckling. Finally, the endochronic theory combined with the principle of virtual work was used to simulate the relationship among the moment, curvature and ovalization of thin-walled tubes under cyclic bending. An empirical formulation was proposed for simulating the relationship between the moment range and the number of cycles necessary to produce buckling for thin-walled tubes subjected to cyclic bending with different moment ratios. The results of the experimental investigation and the simulation are in good agreement with each other.

• 한국정보디스플레이학회:학술대회논문집
• /
• 2007.08b
• /
• pp.1583-1585
• /
• 2007

The purpose of this research is to control proper processing condition of RGB photo resistant in the ink-jet process increasing processing ability by adding additives. The viscosities of modified RGB photo resistant were $10{\sim}14cps$ and the additives could decreased agglomeration and flowing trace of photo resistant effectively. Another way, the adhesion between photo resistant and glass substrate was improved by modifying photo resistant and substrate. The surface tensions of modified photo resistant were same as that of original RGB photo resistant. The additives appeared a better compatibility with photo resistant, and the micelle of photo resistant did not be broken during modified process.

• Structural Engineering and Mechanics
• /
• v.26 no.1
• /
• pp.1-14
• /
• 2007

Because of complexity, the literature regarding the free vibration analysis of a Timoshenko beam carrying "multiple" spring-mass systems is rare, particular that regarding the "exact" solutions. As to the "exact" solutions by further considering the joint terms of shear deformation and rotary inertia in the differential equation of motion of a Timoshenko beam carrying multiple concentrated attachments, the information concerned is not found yet. This is the reason why this paper aims at studying the natural frequencies and mode shapes of a uniform Timoshenko beam carrying multiple intermediate spring-mass systems using an exact as well as a numerical assembly method. Since the shear deformation and rotary inertia terms are dependent on the slenderness ratio of the beam, the shear coefficient of the cross-section, the total number of attachments and the support conditions of the beam, the individual and/or combined effects of these factors on the result are investigated in details. Numerical results reveal that the effect of the shear deformation and rotary inertia joint terms on the lowest five natural frequencies of the combined vibrating system is somehow complicated.