• Title/Summary/Keyword: Korean volunteers

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Safety of Ojeok-san Extract Powder and Soft Extract in Healthy Male Volunteers, Single Center, Randomized Controlled, Cross-over Study (오적산 혼합단미엑스산제와 혼합단미연조엑스제의 안전성 평가를 위한 단일 기관, 무작위 배정, 교차 연구)

  • Shin, Hee-Ra;Park, Kyungtae;Yeom, Seung-Ryong;Kwon, Young-Dal
    • Journal of Korean Medicine Rehabilitation
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    • v.29 no.1
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    • pp.63-73
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    • 2019
  • Objectives The purpose of this study is to evaluate the safety of Ojeok-san extract powder and soft extract in healthy male volunteers. Methods Randomized controlled, cross over study was carried out in healthy male volunteers. Total 27 of 31 subjects meeting the inclusion criteria were enrolled and three subjects for waiting were included. To each group 12 subjects were randomly allocated by random number table. Group A took the extract powder in the first period and then took the soft extract in the second period. Group B took the medicine in the opposite order. Trial was conducted through two times of hospitalizations and all subjects had a seven-days of wash out period. Vital sign and laboratory test were checked before and after the medication. The mean difference of safety evaluation variables were analyzed by paired t-test (p<0.001) or wilcoxon signed rank test (p<0.05). The mean difference between two groups were analyzed by independent t-test (p<0.05) or Mann whitney test (p<0.05). Results As a result of all data related to vital sign and laboratory test in both group, There were no significant differences associated with the clinical trial drug between before and after the medication. And there was no adverse event associated with the clinical trial drug. Conclusions Both Ojeok-san extract powder and soft extract were found to be safe for healthy male volunteers.

Pharmacokinetic Study of Levosulpiride Tablets in Human Volunteers

  • Lee, Jung-Min;Yoon, Mi-Kyeong;Lee, Sung-Jae;Kim, Sun-Kyu;Choi, Young-Wook
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.240.3-241
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    • 2003
  • The purpose of this trial was to determine pharmacokinetic parameters and to characterize bioavailability of levosulpiride after oral administration in Korean healthy male volunteers. Thirty subjects were received a single oral dose of a tablet (Isomeric$\^$\ulcorner/) containing 25 mg of levosulpiride. The plasma concentrations of levosulpiride were measured by a validated FLD-HPLC method and compared with those reported in the literature. Levosulpride was absorbed slowly, revealing peak concentrations between 4 and 6 hr after oral administration. (omitted)

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Elderly Residents' Behavior Problems as Experienced by Volunteers Working in Low-Income Welfare Facilities (자원봉사자가 경험한 저소득층 복지시설 거주노인의 문제행동)

  • Lee, In-Soo
    • Journal of Families and Better Life
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    • v.25 no.1 s.85
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    • pp.127-144
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    • 2007
  • This study was conducted for the purpose of analyzing volunteer workers' perceptions of and attitudes toward the behavior problems of the elderly residents after caring for the residents voluntarily at low-income nursing homes. Eleven male and female volunteers ranging from age 19 to 52 were asked how they felt about the elderly residents' behavior problems and what kind of behavioral problems they had experienced after doing volunteer works in the three chosen facilities. In particular, they were expected to explain what emotional changes they experienced during their volunteer service. In this study, it was observed that most of the elderly subjects experienced three categories of behavior problems: habitual, repetitious and unreasonable activities caused by the elderly residents' life span backgrounds, unexpected and/or abrupt behaviors resulting from gradual cognitive impairments, and physiological, awkward activities caused from gradual senility. The volunteers tend to believe that the elderly residents are naturally expected to act positively, since they have been provided with well- planned, regular care services such as bathing, counseling, activity programs, and religious guidances. On the other hand, some respondents stated that their experiences at the nursing homes caused them to form negative images of the elderly; they feel that the elderly are not helpful for giving advices on critical decisions, guiding and encouraging their daily lives, and offering any positive influences toward their own lives. Rather, they find themselves getting too much stressed as a result of their intimate contacts with demented or senile residents. Overall, in this study, it is proposed that education for confronting sudden abrupt behavior problems should be intensified more for female volunteers, since they tend to be more susceptible to emotional harassment resulting from the problem behaviors. It is also proposed that young volunteers who have not been systematically trained for confronting aggressive behaviors need to be separately assigned their roles in order to minimize the potential of confronting unseemly situations resulting from male residents whose mental health has deteriorated. Furthermore, it is also suggested that the combination of leisure-related activities for healthy residents and stressful intimate services for the frail residents be systematically planned and implanted for the volunteer program so that the volunteers can lessen the chances of suddenly finding themselves confronted with extremely abrupt agitations.

Coverage Method in German Workers' Compensation Insurance and Policy Implications: Focusing on Volunteers and Persons in Special Types of Employment (독일 산재보험제도의 적용방식과 시사점: 자원봉사자와 특수형태근로종사자 중심으로)

  • Kim, Sang Ho
    • 한국사회정책
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    • v.20 no.3
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    • pp.171-195
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    • 2013
  • One of the current issues in Workers' Compensation Insurance is about the coverage range. Korea uses the definition of worker under the Labor Standards Act in Workers' Compensation Act and solved the problems associated with the coverage range of insurance group by the exceptional clause only for the groups which was raised about the need for the social protection. The purpose of this paper is to draw implications for solving problems which are associated with the coverage range of insurance group by reviewing the German literature. We focus on volunteers and persons in special types of employment. German government supports the activity of volunteers by providing with the protection service against the accidents. This paper shows how the coverage range is extended from the dependent employees in the introduction of the Workers' Compensation Insurance to the people who need social protection focusing on the volunteers. The implications of this research are following. First, German system shows that Workers' Compensation Insurance can be extended to the groups which do not belong to the dependent employee but are worthy of protection. Second, it is necessary to provide volunteers in the social welfare system with the protection service against the accidents and the statutory accident scheme is recommendable to use. Third, volunteers in the social welfare system need to be compulsory insured. Fourth, Korea should find their own way in solving problems associated with persons in special types of employment.

Pharmacokinetic Analysis of Levofloxacin in Healthy Korean Volunteers

  • Kim, Seung-Yong;Chung, Youn-Bok;Pyo, Hee-Soo;Kwon, Oh-Seung
    • Journal of Pharmaceutical Investigation
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    • v.38 no.4
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    • pp.235-240
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    • 2008
  • A sensitive and simple method of determining the plasma levofloxacin (LFX, CAS 100986-85-4) concentrations in human volunteers by liquid-liquid extraction were developed and validated by using a high-performance liquid chromatography/diode array detector. The method was also applied to pharmacokinetic study of LFX. LFX was orally administered to 8 healthy male Korean volunteers at single lowest dose of 200 mg, compared to the published reports in which more than 500 mg of LFX was orally administered. LFX in human plasma was determined. The detection limit of LFX was $0.05\;{\mu}g/mL$. $C_{max}$ value was $2.48{\pm}0.67\;{\mu}g/mL$. $AUC_{0{\to}24\;hr$} and $AUC_{0{\to}{\infty}}$ were $14.52{\pm}3.35\;{\mu}g/mL$ and $16.00{\pm}3.66\;{\mu}g{\cdot}hr/mL$, respectively. The terminal half-life was $6.87{\pm}0.46\;hr$. Our pharmacokinetic parameters were very consistent with that previously reported, showing good correlation between LFX doses and AUC ($r^2=0.995$). This method can be useful for the pharmacokinetics and bioequivalence study with relatively low dose for reducing the main side effects of LFX.

The study of non-contact/non-invasive pulse analyzing system using Optical Coherence Tomography (OCT) for oriental pulse diagnosis (비접촉식 광생체단층촬영 기술을 이용한 맥진 연구 -맥의 빠르기, 크기 및 맥력을 중심으로-)

  • Na, Chang-Su;Youn, Dae-Hwan;Kim, Young-Sun;Lee, Chang-Ho;Jung, Woon-Sang;Kim, Jee-Hyun;Choi, Chan-Hun
    • Korean Journal of Acupuncture
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    • v.26 no.2
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    • pp.1-13
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    • 2009
  • Objective: Optical Coherence Tomography (OCT) has emerged as an important optical imaging modality in non-invasive medical diagnostics. Hence, the aim of this study is to measure the similarity of the diagnosis by a traditional method using doctor's hand for feeling of pulse and by the non-contact/non-invasive pulse analyzing system using OCT on Chon(寸), Kwan(關), Chuk(尺). Method: Four korean medical doctors and the non-contact/non-invasive pulse analyzing system using OCT have measured the rapidity, the dimension, and the power of pulse waves of 25 volunteers. First, four korean medical doctors measured pulse waves of volunteers. During measuring, four doctors were separated from each other and so were volunteers. And then, the pulse waves of volunteers were measured by OCT. This was performed on the right Chon(寸), Kwan(關), Chuk(尺). Results: The study showed that the traditional method and the OCT based method had the 88% matches on the values of the slow and rapid pulse condition (遲數), 64% matches on the values of the small and big pulse condition(微細弱緩大[洪]), and 72% matches on the values of the weak and strong pulse condition(虛實). Conclusions: Based on the high similarities of the measurements of two approaches, we suggest that the OCT based pulse diagnosis method is useful for compensating the traditional method for the pulse diagnosis.

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A Study on the Volunteer Activities in School Library in the Seoul Dongjak District Office of Education (초등학교 도서관의 학부모 자원봉사자 운영 활성화 방안에 대한 연구 - 서울시 동작.관악구 초등학교를 중심으로 -)

  • Cho, Chan-Sik;Kim, Ah-Reum
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.23 no.4
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    • pp.219-237
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    • 2012
  • As school libraries increase quantitatively, the importance of volunteer activities in school library is highly emphasized. In that regard, this thesis approaches and discusses the concept of the school library and school library volunteers systematically through the literature review. Surveys and interviews were conducted to investigate and analyze school library volunteers. The survey was completed by school librarians and school library volunteers separately from the 12 elementary schools in the Seoul Dongjak District Office of Education. The current situation of school library volunteers has been analyzed through surveys and accompanied interviews and, based on the analysis, some suggestions were made to improve school library voluntary activities.

Effectiveness of Cold Stress Thermography in the Diagnosis of Complex Regional Pain Syndrome Type 1 (복합부위통증증후군 1형 환자에서 한냉부하 적외선체열촬영의 유용성 평가)

  • Park, Eun Jung;Han, Kyung Ream;Chae, Yun Jeong;Jeong, Won Ho;Kim, Chan
    • The Korean Journal of Pain
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    • v.19 no.2
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    • pp.159-163
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    • 2006
  • Background: Despite the enormous amount of basic research on neuropathic pain, there is the lack of an objective diagnostic test for complex regional pain syndrome (CRPS). The aim of this study was to evaluate the usefulness of cold stress thermography in the diagnosis of CRPS. Methods: The study involved 12 patients with CRPS type 1, according to the IASP criteria, who were compared with 15 normal healthy volunteers. All subjects underwent thermographic examination under baseline conditions at $21^{\circ}C$. A cold stress test (CST; $10^{\circ}C$ water for 1 minute) was then applied to both hands below the wrists, immediate, and after 10 and 20 minutes. Results: The temperature asymmetry between the patients with CRPS and the volunteers showed significant discrimination at the baseline and after a 20 minute recovery period from the CST. Among the study subjects having temperature asymmetry of both hands of less than $1^{\circ}C$ (8 out of 12 CRPS patients and 14 out of 15 volunteer), 7 (87.5%) of the 8 CRPS patients and 3 (21%) of the 14 volunteers showed a temperature difference of more than $1^{\circ}C$ after the 20 minute recovery period. The actual temperature values during the four periods did not discriminate between the patients with CRPS and the volunteers. Conclusions: Thermography, under the CST, could be a more objective test for the diagnosis of CRPS. A temperature asymmetry greater than $1^{\circ}C$ during the 20 minute recovery period following CST provides strong diagnostic information about CRPS, with both high sensitivity and specificity.

The Effects of Motivation and Continuing Factors on the Satisfaction of Volunteer Activities and Marketing Intention for Volunteers in Public Libraries (공공도서관 자원봉사자의 참여동기와 지속요인이 자원봉사활동 만족도와 마케팅 의도에 미치는 영향에 대한 연구)

  • Lee, Go-Eun;Kim, Giyeong
    • Journal of the Korean Society for information Management
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    • v.38 no.1
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    • pp.87-112
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    • 2021
  • Volunteers in public libraries are recognized only as internal manpower, so their sustainability and effectiveness are limited because the motivation for volunteering is hardly considered. This study aims to explore the motivation for volunteering in public libraries and the factors to continuation of the volunteering, and to analyze how these factors affect volunteer satisfaction and marketing intentions. To this end, the variables in this studies including satisfaction and motivation was defined operationally based on the related research and a pilot study with several in-depth interviews. A questionnaire survey was executed with the defined variables and the survey data were analyzed statistically. The results showed that the factors of emotional and psychological motivation influenced the satisfaction and marketing intention rather than the managerial factors such as remuneration. The results indicate the need for a change in volunteer management to a relationship-oriented management method. This study is meaningful in that it expands the value of volunteers in public libraries from as managerial to as marketing resources for public libraries.

Study on Effects of Incense Smokes Composed with Oriental Medical Herbs on HRV and Stress Relaxation (한약재 훈법(熏法)의 심박변이도 및 스트레스 이완에 미치는 임상 효과)

  • Hwang, Chi-Hyuk;Kim, Kyoung-Shin;Uhm, Ji-Tae;Hwang, Seock-Yeon;Jo, Hyun-Kyung;Kim, Byoung-Soo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.4
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    • pp.566-571
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    • 2012
  • The purpose of this study was to assess the effects of herbs aroma on relaxation in highly stressed volunteers with heart rate variability(HRV) and SACL(stress arousal check list). 28 highly stressed volunteers participated in this study. The volunteers were examined with heart rate variability(HRV) and SACL(stress arousal check list) before and after smell herbs aroma. After smelling powder incense composed with oriental medicine herbs, mean RR, SDNN, LF, HF, TP were incresed and mean HRV, LF/HF ratio were decreased, but it was not significant. And VLF, norm HF were incresed and norm LF was decreased significantly. This results show that the powder incense composed with oriental medicine herbs effects on decresing sympathetic nervous activity and increasing parasympathetic activity and rebalancing autonomic nervous system who were under stress.