• 대한한방부인과학회지
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• 제27권3호
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• pp.175-188
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• 2014

Objectives: The study was implemented to observe how Oriental Medicine Music Therapy (Korean Medicine Music Therapy) influences on curing the symptoms of anger and depression. Methods: Study conducted an experiment with an age of 43 female who usually suffers from headache and dizziness, and frequently gets angry at her daughter. The Study was conducted for an hour, 1 times a week. In the present study, the whole program consisted of 7 sessions. Other than the Oriental Medicine Music Therapy, the patient had never been cured by other treatments. Results: 1. According to the result of STAXI analysis, the patient with anger scale of 36 (before treatment) became to have anger scale of 31 after the treatment, indicating that the therapy had positive effect on curing the anger symptom. 2. Moreover, the analysis result of BDI showed that the patient with depression scale of 17 (before treatment) turned out to be non-depression state, which he had the depression scale of 8. Regarding the results above, it was observed that the treatment cured the depression symptom. 3. Based on the result of SEI analysis, the patient with a SEI score of 139 (higher the SEI score, more the self-esteem one has) became to have score of 142 after the treatment. Conclusions: From the research, it was observed that Korean Medicine Music Therapy has positive influence on improving one's anger or depression control and self-esteem. Clinical trial is needed to verify statistical significance.

• Journal of Oral Medicine and Pain
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• 제45권3호
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• pp.79-82
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• 2020

Tetanus is a fatal disease caused by the infection Clostridium tetani found in animal feces and soil. It is a vaccine-preventable disease and rarely occurs in developed countries. However, approximately 30 cases still occur annually in South Korea. Tetanus, commonly called lockjaw, cause contraction of the masseter muscles in the early stage, resulting in trismus as the first symptom. As it progresses, spasm extends to various muscles in the face, neck, shoulder, and back, leading to distorted facial expression, dysphagia, backward arching of the body, dyspnea, and even death. Early diagnosis of tetanus is critical because it can quickly become fatal if left untreated. We present a case of trismus caused by tetanus and emphasize the importance of early diagnosis of acute trismus.

• 분석과학
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• 제9권1호
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• pp.107-111
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• 1996

Bipolaris cynodontis의 배양 추출물로부터 이탈리안 라이그라스 뿌리의 생육저해 활성을 나타내는 물질을 분리 정제한 다음에 2차원 NMR을 포함한 각종 기기분석을 이용하여 구조를 결정하였다. 이 화합물의 분자식은 $C_{24}H_{30}O_5$ 이었으며 세스퀴테르펜류 화합물로 이탈리안 라이그라스 및 벼와 같은 벼과식물에 대해서 100ppm에서 100%의 활성을 나타내는 것으로 보아 병원균의 병징 발현에 관여하는 것으로 보여진다.

• 대한의생명과학회지
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• 제23권4호
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• pp.303-309
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• 2017

${\beta}$-sitosterol, one of phytosterols, exhibited numerous pharmacological effect including anti-inflammatory, anti-cancer and immune-modulating properties. This study attempted to determine the pharmacological effects of ${\beta}$-sitosterol on atopic dermatitis (AD). We investigated to ascertain the pharmacological effects of ${\beta}$-sitosterol on 2, 4-dinitrochlrobenzene (DNCB)-induced AD symptom and histamine-induced scratching behaviors in mice. Additionally, we evaluated the effects of ${\beta}$-sitosterol on the interleukin (IL)-6 levels in HaCaT cells and skin tissue of AD. The findings of this study demonstrated that ${\beta}$-sitosterol reduced AD clinical symptoms such as eczematous, erythema and dryness and serum histamine and IgE levels in DNCB-induced AD model and histamine-induced scratching behaviors in mice. Additionally, ${\beta}$-sitosterol inhibited the IL-6 expression in AD-like skin lesion and HaCaT cells. Collectively, these findings provide that ${\beta}$-sitosterol could be a therapeutic agent for skin inflammation including AD.

• Nutritional Sciences
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• 제5권4호
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• pp.190-196
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• 2002

Zinc deficiency has been shown to result in poor appetite, causing anorexia. However, the role of zinc in the regulation of food intake is not well understood. In the present study, we hypothesized that zinc deficiency dysregulates circulating leptin level and leptin mRNA gene expression, and that whether these changes were occuring as a direct result of, or as a compensatory effect of zinc deficiency in rats. After an adaptation period of 4 weeks, Sprague Dawley rats were provided with three different level of zinc, as one week of a Zn-adequate (30 mg/kg) diet, then two weeks of a Zn-depletion (1 mg/kg ), and finally by two weeks of a Zn-repletion (50 mg/kg) diet. At the end of each dietary experimental period, one third of the 26 rats were killed. Zinc levels of blood subfractions (plasma, yee blood cells and mononuclear cells) and in the liver were substantially decreased, despite the fact that food intake was not substantially decreased during the Zn-depletion period. Serum leptin concentration was significantly increased during the zinc depletion period. Leptin mRNA in adipose tissue was also shown to be highly expressed during the Zn-depletion period. Presumably, increased leptin level and leptin mRNA induction during Zn-depletion conditions may be the cause of lowered appetite which is the common symptom of Zn-deficiency. In conclusion, These increases in circulating leptin levels and in leptin gene expression would be the direct result of, rather than the compensatory effect of, zinc deficiency.

• The Plant Pathology Journal
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• 제27권2호
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• pp.170-182
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• 2011

Plants possess multiple resistance mechanisms that protect themselves against pathogen attack. To identify unknown components of the defense machinery in Arabidopsis, gene-expression changes were monitored in Arabidopsis thaliana under 18 different biotic or abiotic conditions using a DNA microarray representing approximately 25% of all Arabidopsis thaliana genes (www.genevestigator.com). Seventeen genes which are early responsive to salicylic acid (SA) treatment as well as pathogen infection were selected and their T-DNA insertion mutants were obtained from SALK institute. To elucidate the role of each gene in defense response, bacterial pathogen Pseudomonas syringae pv. tomato (Pst) DC3000 was inoculated onto individual T-DNA insertion mutants. Four mutants exhibited decreased resistance and five mutants displayed significantly enhanced resistance against Pst DC3000-infection as measured by change in symptom development as compared to wild-type plants. Among them, member of uridin diphosphate (UDP)-glycosyltransferase (UGT) was of particular interest, since a UGT mutant (At1g05680) showed enhanced resistance to Pst-infection in Arabidopsis. In systemic acquired resistance (SAR) assay, this mutant showed enhanced activation of SAR. Also, the enhanced SAR correlated with increased expression of defense-related gene, AtPR1. These results emphasize that the glycosylation of UGT74E2 is a part of the SA-mediated disease-resistance mechanism.

• 전기전자학회논문지
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• 제26권3호
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• pp.430-436
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• 2022

본 논문에서는 다중 체온 감지용 지능형 카메라를 제안한다. 제안하는 카메라는 광학(4056*3040) 및 열화상(640*480) 2종의 카메라로 구성되고 획득된 영상으로부터 사람의 표정 및 체온을 분석하여 이상 증상을 감지한다. 광학 및 열화상카메라는 동시에 운영되며 광학 영상에서 객체를 검출한 후 얼굴영역을 도출하여 표정분석을 수행한다. 열화상카메라는 광학카메라에서 얼굴영역으로 판단한 좌표 값을 적용하고 해당영역의 최고 온도를 측정하여 화면에 표출한다. 이상 징후 감지는 분석된 표정 3가지(무표정, 웃음, 슬픔)와 체온 값을 활용하여 판단하며 제안된 장비의 성능을 평가하기 위해 광학영상 처리부는 Caltech, WIDER FACE, CK+ 데이터셋을 3종의 영상처리 알고리즘(객체검출, 얼굴영역 검출, 표정분석)에 적용하였다. 실험결과로 객체검출률, 얼굴영역 검출률, 표정분석률 각각 91%, 91%, 84%을 도출하였다.

• 한국심리학회지 : 문화 및 사회문제
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• 제23권3호
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• pp.333-359
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• 2017

본 연구는 일과 삶의 균형이 우울, 불안, 신체화증상 등 정신건강에 미치는 영향을 확인하고, 정서표현에 대한 부정적 신념과 정서명료성이 이들 관계를 조절하는지를 확인하고자 하였다. 그리고 성별에 따라 조절효과에 차이가 있는지를 살펴보고자 하였다. 이를 위해 30대~50대의 기혼직장인 869명(남: 424명, 여: 445명)을 대상으로 설문조사를 실시하였다. 그 결과, 일과 삶의 균형이 높을수록, 부정적 정서신념이 낮을수록, 정서명료성이 높을수록 우울, 불안, 신체화증상이 유의하게 낮아지는 경향을 보였다. 일과 삶의 균형과 우울 및 불안 간의 관계에서 부정적 정서신념의 조절효과는 유의한 반면 정서명료성은 유의한 조절효과를 보이지 않았다. 부정적 정서신념과 정서명료성의 조절효과에 있어 성차가 있는지 확인한 결과, 일과 삶의 균형과 우울, 불안, 신체화증상 간 관계에서 부정적 정서신념의 조절효과는 여성의 경우에만 유의하게 나타났다. 반면 일과 삶의 균형과 우울 및 불안과의 관계에서 정서명료성의 조절효과는 남성의 경우에만 유의하게 나타났다. 마지막으로, 이상의 결과가 갖는 함의를 논의하였다.

• The Plant Pathology Journal
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• 제18권2호
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• pp.85-92
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• 2002

A new isolate of Cucumber mosaic virus (CMV), identified as Li-CMV was isolated from a diseased Korean native lily (Lithium tsingtauense Gilg). Biological and serological properties of Li-CMV were characterized, and reverse transcription-polymerase chain reaction (RT-PCR) analysis, restriction enzyme profiling of RT-PCR products, and nucleotide sequence analysis of RNA3 of the virus were performed in this study. Remarkable differences in symptoms between Li-CMV and ordinary CMV strains were found in tobacco plants and Datura stramonium. Li-CMV-infected tobacco plants (cv. Xanthi-nc and cv. Samsun) induced chlorotic ringspots on uninoculated upper leaves, and the symptom expression was delayed or faint whereas, ordinary CMV strains induced green mosaic symptoms on the plant. Systemic infections were observed on Nicotiana benthamiana with severe mosaic symptom. Restriction mapping analysis of RT-PCR products using MspI showed that Li-CMV belonged to CMV subgroup I. A full-length CDNA copy of RNA3 for the virus was amplified by RT-PCR, cloned, and its complete nucleotide sequence was determined. The RNA3 of Li-CMV was 2, 232 nucleotides long, and consisted of two open reading frames of 843 and 657 bases encoding 3a protein (movement protein) and coat protein, respectively. Results of this study indicate that Li-CMV is a novel strain and belongs to subgroup I of CMV in the genus Cucumovirus.

• 한국식물병리학회지
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• 제1권3호
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• pp.184-189
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• 1985

뽕나무 오갈병 마이코플라스마가 매개곤충인 마름무늬매미충에 의하여 5가지 초본식물(일일초, 화이트클로우버, 라디노클로우버, 레드클로우버, 자운영)에 전염되었음이 병징발현과 광학 및 전자현미경적 방법에 의하여 확인되었다. 전염된 식물에서는 마름무늬매미충이 적어도 25일 이상 생존하였고, 산란이 확인되었다. 이 병의 잠복기간은 일일초에서 $25\~30$일, 클로우버류와 자운영에서는 $35\~40$일로 나타났다. 감염된 식물의 공통된 병징은 잎의 변색으로, 일일초는 엽맥투화 및 황화, 화이트 및 라디노클로우버는 갈색, 레드클로우버는 적색, 자운영의 잎은 광색으로 각각 나타났다. 한편 클로우버류와 자운영에서는 상기한 잎의 변색과 함께 식물체에 위축병상이 나타났다. Dienes 염색에 의한 광학현미경적 진단방법은, 모든 이병식물의 줄기 사부가 특이하게 염색디어 뽕나무 오갈병 마이코플라스마의 검출에 신빙성이 있고, 사용하기에 간편한 것으로 나타났다. Toluidine blue 염색에 의한 광학현미경적 방법과 전자현미경 관찰로, 이병식물조직내에서 마이코플라스마의 존재가 확인됨으로써 이 병의 전염이 입증되었다.