• Journal of Chest Surgery
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• 제53권2호
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• pp.53-57
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• 2020

Background: Video-assisted thoracoscopic surgery (VATS) lobectomy has become the major surgical option for the treatment of non-small cell lung cancer (NSCLC). Endoscopic instruments such as stapler cartridges are essential for VATS procedures. In this study, we investigated the factors that affect the number of stapler cartridges used in VATS lobectomy. Methods: A retrospective analysis was conducted of patients who underwent complete VATS lobectomy for NSCLC from January 2013 to December 2015. Results: In total, 596 patients underwent complete VATS lobectomy. The average number of stapler cartridges used for VATS lobectomy was 5.3±1.9. The number of stapler cartridges used for VATS lobectomy was higher in men (5.5±1.9 vs. 5.0±18, p=0.006), those aged older than 70 years (5.5±2.1 vs. 5.1±1.7, p=0.038), those who underwent upper or middle lobectomy procedures (5.7±1.9 vs. 4.1±1.2, p<0.001), those with a higher fissure sum average (p<0.001), and those in whom surgery was performed by a surgeon with a preference for staplers (5.6±2.0 vs. 4.9±1.6, p<0.001). Conclusion: The number of stapler cartridges required to perform VATS lobectomy in NSCLC patients appears to be influenced by sex, age, the location of the tumor, the degree of fissure development, and the surgeon's preference.

• Parasites, Hosts and Diseases
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• 제23권2호
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• pp.214-220
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• 1985

극구흡충류(echinostomes)의 하나인 Echinochassnus iaponicus 성충이 1984년 4월 인체로부터 회수되어 이 홉충에 의한 자연 인체감염이 처음으로 증명되었다. 환자는 요꼬가와흡충 유행지로 알려진 절남 탐진강 유역 강진군에 거주하는 33~55세 남자 3명과 62세 여자 1명, 도합 4명으로 이들을 10mg/kg praziquantel로 치료하고 하제를 사용한 후 설사변에 배출된 모든 흡충 및 조충을 수집하였다. 충체 수집결과 많은 수의 요꼬가와흡충이 배출된 것이 확인되었으나 이들과 함께 1~4 종류의 다른 흡충 또는 조충이 발견되었고 특히 E. japonicus 1~43마리 (총 54마리)가 검출되었다. 환자들은 이들 장내 윤충류의 복합감염으로 소화불량, 복부불쾌감 등 위장관 증상을 호소하였고 강 유역에서 각종 잉어숴 어류나 은어를 잡아 생식해온 경력이 있었다. 이들 극구흠충은 길이 0.66~0.99mm이었고, 두관 주위의 두극이 총 담개로 구흡반 배측에시 연결이 끊어져 있었고, 자궁내 충란수가 2개 이내인 점, 충란의 크기가 $76~87{\mu\textrm{m}}$(길이)인 점 등으로 Echinochasmus iaponicus Tanabe, 1926으로 동정되었다.

• Tuberculosis and Respiratory Diseases
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• 제78권4호
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• pp.396-400
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• 2015

IgG4-related disease is an immune-mediated fibro-inflammatory disease, characterized by lymphoplasmacytic infiltration composed of IgG4-positive plasma cells of various organs with elevated circulating levels of IgG4. This disease is now reported with increasing frequency and usually affects middle-aged men. Massive pleural effusion in children is an uncommon feature in IgG4-related disease. Here, we report a case of a 16-year-old male patient with extensive IgG4-related disease presenting with massive pleural effusion, mediastinal mass, and mesenteric lymphadenopathy.

• Archives of Plastic Surgery
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• 제34권4호
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• pp.504-507
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• 2007

Purpose: Chondroid syringoma, previously known as 'mixed tumor of the skin', is a rare benign tumor. It usually presents an asymptomatic solitary firm intradermal or subcutaneous slowly growing nodule. It occurs frequently in the head and neck region of middle-aged men. We would like to report an uncommon chondroid syringoma about the clinical and histologic presentation. about the clinical and histologic presentation. Methods: We experienced two cases of chondroid syringoma on the nose and the upper lip, each other. Both masses were totally excised with clear margin. Results: On histologic examination, the masses showed a biphasic pattern-an epithelial component exhibiting apocrine/eccrine differentiation and a stromal component exhibiting myxoid/collagenous change-consistent with the diagnosis of chondroid syringoma. There have been no evidence of recurrence and malignant transformation during postoperative follow-up. Conclusion: There is no one distinctive clinical feature that is specific for chondroid syringoma. However, it should be included in the differential diagnosis of a solid nodule in head and neck region with long standing duration, such as epidermal inclusion cyst, pilomatrixoma, dermoid cyst, sebaceous cyst, neurofibroma, and basal cell carcinoma.

• 구강회복응용과학지
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• 제35권3호
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• pp.123-131
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• 2019

구강작열감 증후군은 점막 이상 등의 임상소견이 없는 상태에서 혀 및 구강점막의 작열감과 구강건조감, 미각이상 등의 불편감을 호소하는 증상으로, 남녀 모두에서 나타날 수 있으나 중년의 폐경기 여성에서 빈발한다. 임상에서 진단이 쉽지 않고 명확한 원인을 밝히기 어려워 증상 경감을 치료목표로 해왔다. 병인은 국소적, 전신적 및 심리적 요인으로 나뉘고 치료는 ${\alpha}$-lipoic acid, clonazepam, 영양보충 등의 약물요법과 인지행동치료 등이 있으며 최근에는 단일 치료법보다는 복합요법의 높은 효과에 대해 관심이 모아지고 있다. 다각적인 면에서 원인요소를 고려하여 약물적 접근과 인지행동요법을 포함한 심리치료 병행으로 환자들의 증상을 경감해주는 것이 필요하다.

• 수산경영론집
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• 제50권3호
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• pp.1-15
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• 2019

The purpose of this study is to analyze the differences by comparing consumption tendency of the Flatfish and Salmon using focus group interview (FGI). The FGI was conducted on university students in their 20s, with a total of 38 respondents surveyed in seven focus groups. Flatfish was recognized as a food in the form of popular sliced raw fish and had customer image that fit for middle-aged men in their 40s and 50s while eating with alcohol. 20s were perceived to be out of date with their age group as flatfish was considered old fish that did not match their age. In addition, they felt low accessibility to flatfish. Salmon was perceived by 20s as a food with a higher appeal than flatfish. Salmon has been creating a brand identity in their 20s and 30s for fashionable and trendy food that appealed to younger generations. They considered characteristics of salmon high in intangible value, such as something sophisticated, trendy, and beautiful. 20s consumed various forms of salmon including salmon sushi, salmon bowl, and salmon fillet, and they perceived it as a psychologically close food that can be easily accessible. In this study, the color of species (orange color of salmon), accessibility, restaurant image, and social media exposure were found to influence the consumption patterns of two species.

• Journal of Ginseng Research
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• 제46권3호
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• pp.473-480
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• 2022

Background: Benign prostatic hyperplasia (BPH) is a disease characterized by abnormal proliferation of the prostate, which occurs frequently in middle-aged men. In this study, we report the effect of red ginseng oil (KGC11o) on BPH. Methods: The BPH-induced Sprague-Dawley rats were divided into seven groups: control, BPH, KGC11o 25, 50, 100, 200, and finasteride groups. KGC11o and finasteride were administered for 8 weeks. The BPH biomarkers, DHT, 5AR1, and 5AR2, androgen receptor, prostate-specific antigen (PSA), Bax, Bcl-2, and TGF-β were determined in the serum and prostate tissue. The cell viability after KGC11o treatment was determined using BPH-1 cells, and, androgen receptor, Bax, Bcl-2, and TGF-β were confirmed by western blotting. Results: In the in vivo study, administration of KGC11o reduced prostate weight by 18%, suppressed DHT (up to 22%) and 5AR2 (up to 12%) levels from administration of 100 mg/kg KGC11o (P < 0.05). PSA was significantly downregulated dose-dependently from at the concentration of 50 mg/kg KGC11o (P < 0.05). BPH-1 cell viability significantly reduced through the treatment with KGC11o. In vitro and vivo, AR, Bcl-2 TGF-β levels reduced significantly but Bax was increased (P < 0.05). Conclusion: These results suggest that KGC11o may inhibit the development of BPH by significantly reducing the levels of BPH biomarkers via 5ARI, anti-androgenic effect, and anti-proliferation effect, serving as a potential functional food for treating BPH.

• 대한가정학회지
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• 제43권5호
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• pp.183-198
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• 2005

The purpose of this study was to discuss the relationship between Korean people's normative sense of the traditional filial piety and their affiliation with relatives. For this purpose, the researcher reviewed ethics books during the Chosun dynasty such as Naehoon Women's Ethics), Dongmongsonsup (Children's Cardinal Moral Principles) ,Kyokmongyokyol (Juvenile's Learning) and Gyuenyoso (Instructions for Daughters of Marriageable Age), Based on this review a questionnaire was designed. For the survey,566 returned questionnaires from married people between their 20's and 70's living in Seoul and Wonju Si were sampled The collected data were analyzed using the SAS program for means and SDs of each area in order to examine the overall tendency, and were subject to one-way ANOVA to determine the relationship between their normative sense of the traditional filial piety and their affiliations with relatives depending on their demographic variables, In addition to this correlation analysis, the data underwent regression analysis to determine the significant factors affecting the subjects' sense of filial piety and their affiliation with relatives. The results of this study can be summarized as follows ; First, the subjects were found to have a normal or higher sense of filial piety in overall terms, which suggests that the Korean morality of filial piety may be positive. In particular, the subjects' sense of filial piety was higher for living parents than for dead ones. Namely, they wanted to give more respect, honor and support to their parents than give a cordial funeral or memorial service to deceased parents. Second, older Koreans were more aware of filial piety, and men were more conscious of filial piety than women. Buddhists or atheists tended to be more faithful to their parents. Generally, those with lower academic background and living with larger families had a higher normative sense of filial piety. On the other hand, those in their 60's and 70's were most affiliated with their relatives, while youth and middle-aged people were less affiliated with their relatives. Men were more affiliated with their relatives than women, and first sons or daughters were more affiliated with their relatives. Besides, those living with larger families were more affiliated with their relatives. Third, the subjects' normative sense of filial piety, particularly for deceased parents, was highly correlated with their affiliation with relatives, and such a normative sense of filial piety was most conspicuous in their funeral rites.

• Journal of Preventive Medicine and Public Health
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• 제39권6호
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• pp.505-510
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• 2006

Objectives : The purpose of this study is to evaluate the association of the angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism with cardiovascular disease risk factors. Methods : Out of a total of 608 middle-aged adults who visited local health centers, 424 subjects (104 male, 320 female) who had not been diagnosed with hypertension, diabetes mellitus, or hyperlipidemia were included in this study. ACE genotypes were determined in all subjects by polymerase chain reaction methods. Results : Statistical differences in high-density lipoprotein (HDL) cholesterol levels according to ACE genotype were observed using ANOVA (p<0.05), but no differences were found in other cardiovascular risk factors. Specifically, men with the DD and DI genotypes had significantly lower HDL cholesterol levels than those with the 11 genotype based on the LSD multi-comparison test (p<0.05). Conclusions : In men, the D-allele of the ACE I/D polymorphism was significantly associated with reduced HDL cholesterol levels. In the future, larger studies are needed to confirm this relationship between ACE I/D polymorphism and HDL cholesterol.

• 한국콘텐츠학회논문지
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• 제12권6호
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• pp.317-327
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• 2012

본 연구는 연령층별 사회경제적 계층, 건강행위, 주관적 건강수준 간의 직 간접 경로를 규명하고 그 영향력을 파악하고자 하였다. 제4기 2차년도(2008) 국민건강영양조사에 참여한 성인 중, 교육, 소득, 직업의 3가지 변수로 사회경제적 계층 구분이 가능한 만 25세 이상 4,987명을 연구대상으로 하여 사회경제적 계층을 교육과 소득은 4단계, 직업은 7단계로 분류하고, 건강행위의 실천이 주관적 건강수준에 미치는 영향은 경로분석을 수행하였다. 복합표본분석으로 chi-square test, t-test, one-way ANOVA를 실시하였다. 그 결과 주관적 건강수준은 사회경제적 계층이 낮을수록 낮았으며 청장년층일수록 더 많은 건강행위가 사회경제적 계층에 따라 차이를 보였다. 낮은 사회경제적 계층일수록 주관적 건강수준이 낮아지는데, 청장년층 여자는 금연과 체중조절, 노년층 남자는 운동이 매개변수로써 간접영향을 주었다. 이를 통해 건강증진사업 기획 시 연령층, 성별, 사회경제적 계층을 고려한 정확한 표적집단 선정과 각 표적집단에 적합한 내용 구성이 필요하리라 본다.