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Long-Term Oncological Outcomes of Reduced Three-Port Laparoscopic Gastrectomy for Early-Stage Gastric Carcinoma: a Retrospective Large-Scale Multi-Institutional Study

  • Lee, Han Hong;Jeong, Oh;Seo, Ho Seok;Choi, Min Gew;Ryu, Seong Yeob;Sohn, Tae Sung;Bae, Jae Moon;Kim, Sung;Lee, Jun Ho
    • Journal of Gastric Cancer
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    • v.21 no.1
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    • pp.93-102
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    • 2021
  • Purpose: With advances in surgical techniques, reduced-port laparoscopic surgery is increasingly being performed for the treatment of gastric carcinoma. Many studies have reported satisfactory short-term outcomes after reduced 3-port laparoscopic gastrectomy (LG). The aim of this study was to investigate the long-term oncological outcomes of 3-port LG in patients with gastric carcinoma. Materials and Methods: We reviewed the medical records of 1,117 patients who underwent LG for gastric carcinoma in three major institutions between 2012 and 2015. The data showed that 460 patients underwent 3-port LG without assistance, and 657 underwent conventional 5-port LG. We compared the overall and disease-free survival rates between the 2 groups. Results: There were 642 male and 475 female patients with a mean age of 56.1 years. Among them, 1,028 (92.0%) underwent distal gastrectomy and 89 (8.0%) underwent total gastrectomy. In the final pathologic examination, 1,027 patients (91.9%) were stage I, 73 (6.5%) were stage II, and 17 (1.5%) were stage III, and there were no significant difference in the pathologic stage between groups. The 3- and 5-port LG groups showed no significant differences in the 5-year overall survival (94.3% vs. 96.7%, P=0.138) or disease-free survival (94.3% vs. 95.9%, P=0.231). Stratified analyses according to pT and pN stages also showed no significant differences in overall or disease-free survival between the two groups. Conclusions: Long-term survival after 3- and 5-port LG was comparable in patients with early-stage gastric carcinoma. The 3-port technique requiring limited surgical assistance may be an appropriate surgical option for this patient population.

Spectral and Nonlinear Analysis of EEG in Various Age Groups (뇌파의 연령별 스펙트럼 및 비선형적 분석)

  • Joo, Eun-Yeon;Kim, Eung-Su;Park, Ki-Duck;Choi, Kyoung-Gyu
    • Annals of Clinical Neurophysiology
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    • v.3 no.1
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    • pp.31-36
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    • 2001
  • Background & Objectives : Fractal Dimension(FD) could be an index of correlation between variable parameters in non-linear chaotic signals. We tried to demonstrate that EEG wave is compatible with chaotic waves by measuring the Lyapunov exponent index and compared the difference of FD between variable age groups(teens, 30's, 50's) Methods : We estimated the Lyapunov exponent index and the FD from digital EEG data among five persons in each normal age groups by using the software which is programmed in our laboratory. Statistical analysis was done with SPSS win 8.0. The statistical differences of Lyapunov exponent index and FD between each electrodes and each age groups were done with ANOVA and paired sample t-test. Result : The Lyapunov exponent indexes were larger than 1 in each electrode and age group. There is no statistical difference in FD between each electrodes and each age groups. Except in 30th age group. In this group the FD of right hemisphere is larger than that of left hemisphere. Conclusion : The result of Lyapunov exponent index means EEG wave is a non-linear chaotic signal. And the results of FD suggest that chaotic parameters of right hemisphere is larger than those of left hemisphere at rest at least in younger people. We think that chaotic parameters can be a useful tool in investigating the variable diseases or brain states.

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Predictors of Anaphylactic Shock in Patients with Anaphylaxis after Exposure to Bee Venom (벌독에 의한 아나필락시스 쇼크 발생의 예측 인자)

  • Kim, Hyung-Joo;Kim, Sun-Hyu;Park, Hyoung-Do;Kim, Woo-Youn;Hong, Eun-Seog
    • Journal of The Korean Society of Clinical Toxicology
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    • v.8 no.1
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    • pp.30-36
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    • 2010
  • Purpose: The purpose of this study is to analyze the clinical characteristics of anaphylaxis and anaphylactic shock caused by bee venom. Methods: We retrospectively collected the data of the patients who experienced anaphylaxis caused by natural bee sting or acupuncture using bee venom from January 1999 to December 2008. Seventy subjects were divided into the shock and non-shock groups. The clinical characteristics, sources of bee venom, treatments and outcomes were compared between the two groups. Results: The mean age of the subjects was $45.5{\pm}16.3$ years old and the number of males was 44 (62.9%). There were 25 patients in the shock group and 45 in the non-shock group. The age was older (p=0.001) and females (p=0.003) were more frequent in the shock group. Transportation to the hospital via ambulance was more frequent in the shock group (p<0.001). No difference was found in species of bee between the two groups. The cephalic area, including the face, was the most common area of bee venom in both groups. Anaphylaxis caused by bee sting commonly occurred between July and October. Cutaneous and respiratory symptoms were the most frequent symptoms related to anaphylaxis. Cardiovascular and neurologic symptoms were more frequent in the shock group. The amount of intravenously administered fluid and subcutaneous injection of epinephrine were much more in the shock group than that in the non-shock group. Conclusion: Older age was the factors related to anaphylactic shock caused by bee venom. Further validation is needed to evaluate the gender factor associated with shock.

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A Comparison for Constitutional Body Type between Korean and Chinese-Korean - Using Propensity Score Matching - (한국인과 연길 거주 조선족의 체질별 체형 비교 연구(Propensity Score Matching을 활용하여))

  • Kim, Hoseok;Baek, Younghwa;Lee, Siwoo;Yoo, Jonghyang
    • Journal of Sasang Constitutional Medicine
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    • v.28 no.1
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    • pp.11-18
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    • 2016
  • Objectives The body shape was a key information for diagnosing the Sasang constitution (SC) in Sasang constitutional medicine. The aim of this study was to compare the body shapes and mainly focusing on the Korean and Chinese-KoreanMethods We calculated the propensity score for each SC type in males and females separately, and compared body shape including 8 circumference and 5 width between Korean and Chinese-Korean according to the sex and SC.Results Koreans have larger trunk and hip area compared to Chinese-Koreans, while Chinese-Koreans have larger abdomen compared with Koreans. Most variables were significantly different among SC types, for both Korean and Chinese-Korean. Especially, the Taeumin (TE) type has the largest body shape compared with the other SC types, it was similar between Korean and Chinese-Korean.Conclusions This study showed that the TE type has the largest body shape, followed by Soyangin (SY) and Soeumin (SE) in order, for both Korean and Chinese-Korean respectively. These results suggests that the body shape of Chinese-Korean is similar with Korean based on SC type.

Assessment and Comparison of SUVs of Three Different PET/CT Scanners (장비에 따른 SUV의 차이와 이에 관한 고찰)

  • Kim, Tae-Yeob;Lim, Jung-Jin;Lee, Hong-Jae;Kim, Hyun-Joo;Kim, Joong-Hyun;Lee, Jae-Sung
    • The Korean Journal of Nuclear Medicine Technology
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    • v.15 no.1
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    • pp.34-38
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    • 2011
  • Purpose: The SUV is a widely used semi-quantitative index in PET for the estimation of radio-tracer accumulation in VOI. In this study, SUVs from three different PET/CT scanners were assessed, and differences between SUVs were evaluated. Materials and Methods: The PET/CT scanners which were assessed in this study were GEMINI, GEMINI TF 64 (Philips) and Biograph True Point True V 40 (Siemens). The NEMA PET phantom (Data Spectrum Corp., USA) was used to evaluate SUVs. The NEMA PET phantom has6.8 kg weight and three hot inserts. Two different activity distributions for the background and inserts were tested. The activity ratio were 3.7:3.7:7.4:11.1 MBq (1:1:2:3) and 1.85:7.4:9.25:11.1MBq (1:4:5:6) for each of background, insert 1, insert 2 and insert 3. Acquisition time was 2 minutes per bed position and NEMA PET phantom could be covered by two bed positions for all PET/CT scanners. The SUVs from each PET/CT scanner were compared with calculated true value. Results: For both activity ratios, all scanners showed similar results. The differences between each scanner were insignificant. Each scanner showed 91.2%, 85.9% and 87.2% of true SUV for GEMINI, GEMINI TF 64, Biograph True Point TrueV, respectively. Conclusion: For all scanners, SUVs were slightly lower than true value. However, the difference between scanners was insignificant. The SUVs from these scanners would be clinically meaningful if their consistent underestimation is kept in mind.

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