• 산업경영시스템학회지
• /
• 제47권1호
• /
• pp.41-50
• /
• 2024

Korea is facing a significant problem with historically low fertility rates, which is becoming a major social issue affecting the economy, labor force, and national security. This study analyzes the factors contributing to the regional gap in fertility rates and derives policy implications. The government and local authorities are implementing a range of policies to address the issue of low fertility. To establish an effective strategy, it is essential to identify the primary factors that contribute to regional disparities. This study identifies these factors and explores policy implications through machine learning and explainable artificial intelligence. The study also examines the influence of media and public opinion on childbirth in Korea by incorporating news and online community sentiment, as well as sentiment fear indices, as independent variables. To establish the relationship between regional fertility rates and factors, the study employs four machine learning models: multiple linear regression, XGBoost, Random Forest, and Support Vector Regression. Support Vector Regression, XGBoost, and Random Forest significantly outperform linear regression, highlighting the importance of machine learning models in explaining non-linear relationships with numerous variables. A factor analysis using SHAP is then conducted. The unemployment rate, Regional Gross Domestic Product per Capita, Women's Participation in Economic Activities, Number of Crimes Committed, Average Age of First Marriage, and Private Education Expenses significantly impact regional fertility rates. However, the degree of impact of the factors affecting fertility may vary by region, suggesting the need for policies tailored to the characteristics of each region, not just an overall ranking of factors.

• Clinical and Experimental Reproductive Medicine
• /
• 제32권1호
• /
• pp.55-64
• /
• 2005

Objective: Human infertility clinics have been faced the demand for improving clinical results. The purpose of this study was to evaluate the effect of microsurgical removal of damaged blastomeres (DB) in frozen-thawed embryos on the clinical outcomes. Methods: From January 2003 to May 2004, out of 258 thawing ET cycles were divided into three groups: Group-1 (n=46): Intact cleavaged embryos after thawing. Remained cycles with embryos containing DB were randomly divided into two groups. Group-2 (n=102): Drilling zona pellucida (ZP) of frozen-thawed embryos by acidified Tyrode's solution. Group-3 (n=110): Drilling ZP and removal of DB. Embryos after microsurgical manipulation were transferred into the uterus of patients. Results: Clinical profiles and the mean number of transferred embryos among three groups were not different. Pregnancy and implantation rates were similar in three groups. It were 30.4% and 9.3% in Group-1, 29.4% and 7.8% in Group-2, and 26.4% and 7.6% in group-3, respectively. Miscarriage rate in Group-3 (37.9%) was slightly higher than those in Group-1 and Group-2 (14.3% and 23.3%), but it was not statistically significant. Conclusion: Intact cleaving embryos after DB removal showed higher potent of pregnancy and implantation. We could not find any improvement of clinical outcome by removal of DB in frozen-thawed embryos.

• Journal of Genetic Medicine
• /
• 제2권2호
• /
• pp.79-81
• /
• 1998

Genetic amniocenteses were performed in a series of 127 patients as a routine study. Samples from the patients were cultured by in situ method, flask method or both according to the state of amniotic fluid. The overall success rate of culture was 97.6% and no culture failure was observed in the flask method. It took 5 days first of all and 8.15 days average from set-up to harvest and there were 7.2 colonies per dish in in situ method. Therefore, it is suggested that in situ method which decreased the mean culture days and made clonal analyses possible, is a clinically available and even more reliable method in parallel with flask method in prenatal diagnosis.

• Toxicological Research
• /
• 제18권2호
• /
• pp.167-174
• /
• 2002

Historical control data have been shown to be valuable in the proper interpretation and validation of reproductive toxicology studies. The present data were compiled from rat fertility and early embryonic development studies conducted at Korea Institute of Toxicology during the 1994∼2001 period. These data were assembled in order to provide background information for the general and reproductive data collected in 11 fertility and early embryonic development studies using Sprague-Dawley rats obtain-ing from the Breeding Facility, Korea Institute of Toxicology, Korea. A total of 274 males and 274 females were used in these studies during the eight-year period. Parameters of fertility and early embryonic development included clinical sign, body weights, food consumption, organ weights, estrus cycle, copulation index, precoital time, fertility index, pregnancy index, sperm parameters, and early embryonic development parameters. Most of the values were comparable to the previous historical control data reported by other investigators. These data can be wed not only as a historical data base for the meaningful interpretation of data from reproductive and developmental toxicity studies, but also as a contribution to biological characterization of Sprague-Dawley rats.

• Journal of Animal Science and Technology
• /
• 제64권6호
• /
• pp.1024-1034
• /
• 2022

Identifying effective biomarkers for the diagnosis of male fertility is crucial for improving animal production and treating male infertility in humans. Ras-related proteins (Rab) are associated with morphological and motion kinematic functions in spermatozoa. Moreover, Rab2A, a Rab protein, is a possible male fertility-related biomarker. The present study was designed to identify additional fertility-related biomarkers among the various Rab proteins. First, the expression of Rab proteins (Rab3A, 4, 5, 8A, 9, 14, 25, 27A, and 34A) from 31 duroc boar spermatozoa was measured before and after capacitation; correlation between Rab protein expression and litter size was evaluated by statistical analysis. The results showed that the expression of Rab3A, 4, 5, 8A, 9, and 25 before capacitation and Rab3A, 4, 5, 8A, 9, and 14 after capacitation were negatively correlated with litter size. Moreover, depending on the cutoff values calculated by receiver operating curves, an increase in litter size was observed when evaluating the ability of the Rab proteins to forecast litter size. Therefore, we suggest that Rab proteins may be potential fertility-related biomarkers that could help select superior sires in the livestock industry.

• 한국사회복지학
• /
• 제57권3호
• /
• pp.337-361
• /
• 2005

본 논문은 OECD 주요 선진국의 출산율 및 가족복지정책의 변화와 특성을 검토해 보고, 가족복지 유형별 출산율을 비교 분석해 본 후, 한국의 가족복지정책 마련에 도움이 될 수 있는 시사점을 탐색해 보았다. OECD 주요 선진국의 출산율은 1970년대에 인구대체수준 이하로 떨어졌으며, 그 이후에도 완만하게 출산율이 감소했으나, 1990년대에는 출산율이 낮아지는 국가들과 높아지는 국가들로 나누어진다. 이러한 출산율 변화 차이는 1970년대 이후 각국이 채택 추진한 가족복지정책과 상당한 관계를 갖고 있음을 암시해 주고 있다. 주요 선진국들은 1970년대 이후 출산율 감소에 관심을 갖고 인구관련 문제를 종합적으로 다루기 위해 범정부차원의 인구관련기관을 설립했으며, 가족복지 지원수준을 높여왔다. 그러나 각국의 가족복지 지원수준과 지원형태(노동중심 또는 양육중심)는 해당국가의 정치적 이념, 문화 역사적 배경, 경제환경 등에 따라 다르게 발전되어 왔다. OECD 주요 국가들의 가족복지정책을 유사한 특성을 가진 국가군으로 유형화하여 유형별 출산율을 비교해 본 결과, 가족복지 지원수준이 높을수록, 양육중심에 비해 노동중심 지원수준 비중이 높을수록 출산율이 높은 것으로 나타났다. 또한 유형별 출산율 변화를 비교해 본 결과에서도 가족복지 지원수준이 높을수록, 양육중심에 비해 노동중심 지원수준 비중이 높을수록 출산율이 증가하거나 출산율 감소가 완화되는 것으로 나타났다. 주요 선진국의 출산율과 가족복지정책 분석을 통해 얻을 수 있는 시사점으로는, 첫째 출산율 및 인구관련 문제를 체계적으로 연구하여 종합적인 대안을 제공해 줄 수 있는 범정부차원의 인구관련기관을 설립할 필요가 있으며, 둘째 가족수당 신설, 출산휴가와 육아휴직의 기간 연장 및 육아휴직급여의 상향조정, 공보육시설 확대 등 가족지원체계를 확대해야 하고, 셋째 양육중심(가족수당 등) 지원수준 보다 노동중심(아동보육시설, 출산휴가 등) 지원수준에 비중을 많이 둘 필요가 있고, 넷째 사회구성원, 특히 청년층에게 자녀를 기르는 것이 어렵지 않으며 행복을 가져다준다는 희망을 갖도록 하는 사회환경을 조성할 필요가 있다.

• 한국가금학회지
• /
• 제30권2호
• /
• pp.95-99
• /
• 2003

본 연구는 육용종계 암컷과수컷의 배웅비를 달리할 경우 종란의 수정율과 부화율에 미치는 영향을 구명하고자 실시 하였다. 육용종계 암컷과 수컷 비율이 각각 9:I(암컷:수컷＝11:99), 11:1(9:99), 및 13:1(8:104) 이 되도록 하여 3.2 ${\times}$ 6.4m 크기의 pen에 사육하였다. 각 처리당 3반복으로, 30주령된 Ross 종계 수컷 112수 암컷 1,208수를 시험에 공시하였다. 30주령시 종란의 수정율은 93 ∼ 94% 내외로 처리간 유의차가 발견되지 않았다.

• 한국아동복지학
• /
• 제60호
• /
• pp.59-86
• /
• 2017

본 연구는 아동수당 제도와 출산율의 관계를 살펴보고자 하는 것이다. 이를 위해 아동수당제도를 도입한 OECD 19개국을 대상으로 1980-2016년까지의 시계열자료를 구성하고 결합회귀분석을 통해 변인 간 관계를 규명하였다. 분석결과는 다음과 같다. 인구사회학적 변인들의 영향력을 통제한 후, 아동수당제도를 비롯한 현금지원정책은 일정 부분 합계출산율에 긍정적인 효과를 보이는 것으로 나타났다. 특히 이러한 효과는 아동수당제도 내 출산 장려기제를 도입한 국가군에서 더 두드러지게 나타났다. 이를 바탕으로 앞으로 도입될 한국의 아동수당 제도가 출산장려책으로서 기능하기 위해서는 아동수당제도 내 출산장려기제를 추가로 도입해 다자녀 가구에 대한 혜택을 강화할 필요성을 제언하였다.

• 한국심리학회지 : 문화 및 사회문제
• /
• 제18권1호
• /
• pp.97-110
• /
• 2012

19세기부터 현재까지 산업화된 국가들을 중심으로 출산율이 급락하고 있는 전세계적인 현상은 진화적인 관점에서 선뜻 이해하기 어렵다. 왜 자원이 더 풍부해진 현대에 들어서 사람들은 자식수를 자발적으로 줄이는가? 본 논문은 현대의 저출산 현상을 설명하는 다양한 진화적 접근들을 요약하고, 이를 토대로 우리 사회의 저출산 문제를 해결할 실마리를 얻고자 한다. 1) 현대의 극히 낮은 출산율은 수렵-채집 생활에 맞추어진 우리의 심리적 적응이 진화적으로 낯선 환경과 불협화음을 일으킴에 따른 부적응적인 부산물이라는 가설, 2) 사회적으로 성공한 사람들이 자녀를 적게 낳는 행동이 전파되거나, 가족 중심의 네트워크가 붕괴하여 출산의 중요성이 덜 강조됨에 따라 저출산이 야기되었다는 유전자-문화 공진화 가설, 그리고 3) 부모가 자녀에게 투자하는 양이 대단히 많이 요구되는 현대의 환경에서 극심한 저출산은 부모의 장기적인 적합도를 최대화하는 적응적인 형질이라는 가설을 차례대로 검토한다. 저출산에 대한 진화적 관점은 저소득층의 출산을 지원하는 정책보다는 모든 사회경제적 계층에서 자녀를 장차 경쟁력 있는 성인으로 키우기 위한 비용을 줄이는 정책을 추진하는 것이 더 효과적임을 시사한다.

• Toxicological Research
• /
• 제17권2호
• /
• pp.97-106
• /
• 2001

Korean ginseng products have been fumigated with ethylene oxide (EO) for sterilization and prolongation of storage periods. However, there had been controversies indicating that the consumption of food treated with EO might cause harmful effects in human. Since, in Korea the use of EO gas for food treatment was banned in 1991. Since then, irradiation technique has been developed as an alternative. This study was carried out to investigate the effects of irradiated ginseng on fertility, and reproductive and developmental toxicity. Either EO gas fumigated or gamma-irradiated ginseng was administered to male rats by oral gavage for 63 days during the premating period. Female rats were administered from 14 days before mating to day 20 of gestation or to day 21 of lactation. The exposure amount of irradiation used was 5, 10 and 30 kGy, respectively. There were no treatment related changes of darns in clinical signs, and parturition. No treatment related changes in food consumption, body/organ weights, male/female reproductive and fertility performances were observed. F1 fetuses showed no external abnormality. Reflex/sensory junctions, physical/behavioral development, and reproductive performance of F1 rats were not adversary affected. The results of this study show that gamma-irradiated ginseng, up to 30 kGy, has no adverse effects on the fertility, reproduction and development in Wistar rats.