• Title/Summary/Keyword: Korean dual system

Search Result 1,904, Processing Time 0.03 seconds

Adenoviral-Mediated Ref-1 Overexpression Potentiates NO Production in Bradykinin-Stimulated Endothelial Cells (Bradykinin으로 자극한 혈관내피세포에서 Ref-1의 세포내 과발현에 의한 NO 생성 증진 효과에 대한 연구)

  • Song, Ju-Dong;Kim, Kang-Mi;Lee, Sang-Kwon;Kim, Jong-Min;Park, Young-Chul
    • Journal of Life Science
    • /
    • v.17 no.7 s.87
    • /
    • pp.905-909
    • /
    • 2007
  • The dual-function protein redox factor-1 (Ref-1) is essential for base excision repair of oxidatively damaged DNA and also governs the activation of many redox-sensitive transcription factors. We examined the role of Ref-1 in regulation of nitric oxide (NO) synthesis employing adenoviral-mediatedoverexpression of Ref-1 in bradykinin-stimulated endothelial cells. Intracellular NO was detected with the NO-sensitive fluorophore DAF-2. Overexpression of Ref-1 potentiates bradykinin-stimulated NO production in endothelial cells. And, cells ifected with AdRef-1 showed higher fluorescence intensity compared with uninfected or AdD1312-infected cells. In parallel with this, over expression of Ref-1 also stimulated endothelial NO synthase (eNOS) enzyme activity, compared with unifected or AdD1312-infected cells, in bradykinin-stimulated cells as well as in unstimulated cells. These results suggest that Ref-1 implicates in endothelium-dependent vasorelaxation resulting from NO production in vascular system.

Construction of web-based Database for Haliotis SNP (웹기반 전복류 (Haliotis) SNP 데이터베이스 구축)

  • Jeong, Ji-Eun;Lee, Jae-Bong;Kang, Se-Won;Baek, Moon-Ki;Han, Yeon-Soo;Choi, Tae-Jin;Kang, Jung-Ha;Lee, Yong-Seok
    • The Korean Journal of Malacology
    • /
    • v.26 no.2
    • /
    • pp.185-188
    • /
    • 2010
  • The Web-based the genus Haliotis SNP database was constructed on the basis of Intel Server Platform ZSS130 dual Xeon 3.2 GHz cpu and Linux-based (Cent OS) operating system. Haliotis related sequences (2,830 nucleotide sequences, 9,102 EST sequences) were downloaded through NCBI taxonomy browser. In order to eliminate vector sequences, we conducted vector masking step using cross match software with vector sequence database. In addition, poly-A tails were removed using Trimmest software from EMBOSS package. The processed sequences were clustered and assembled by TGICL package (TIGR tools) equipped with CAP3 software. A web-based interface (Haliotis SNP Database, http://www.haliotis.or.kr) was developed to enable optimal use of the clustered assemblies. The Clustering Res. menu shows the contig sequences from the clustering, the alignment results and sequences from each cluster. And also we can compare any sequences with Haliotis related sequences in BLAST menu. The search menu is equipped with its own search engine so that it is possible to search all of the information in the database using the name of a gene, accession number and/or species name. Taken together, the Web-based SNP database for Haliotis will be valuable to develop SNPs of Haliotis in the future.

Antimicrobial Active Substances from Entomopathogenic Fungi (Various Applications of Entomopathogenic Fungi)

  • Shin, Tae Young;Woo, Soo Dong;Kim, Jeong Jun
    • 한국균학회소식:학술대회논문집
    • /
    • 2016.05a
    • /
    • pp.13-13
    • /
    • 2016
  • Insects constitute the largest and most diverse group of animals in the world. They also serve as the hosts or nutrient sources for an immense assemblage of pathogens, parasites, and predators. More than 700 fungal species from 100 genera have adopted an entomopathogenic lifestyle. Although entomopathogenic fungi were studied as only biocontrol agents against a variety of pests in various countries, it has been recently focused their additional roles in nature. They are antagonists to/against plant pathogens, endophytes, and possibly even plant growth promoting agents. The potential antimicrobial effect against fungal plant pathogens by an isolate of entomopathogenic fungi including Beauveria bassiana, Lecanicillium spp., and Isaria fumosorosea have been reported since late 1990s, but wasn't reported pathogenicity of the isolate against pests. Later, a Canadian Lecanicillium sp. isolate and L. longisporium isolated from Vertalec$^{(R)}$ showed simultaneous control effect against both aphid and cucumber powder mildew. Therefore, the antimicrobial activities of 342 fungi isolates collected from various regions and conditions in Korea were evaluated against plant pathogenic fungus Botrytis cinerea using dual culture technique on agar plate. As a result, 186 isolates (54.4%) shown the antifungal activity against B. cinerea. The culture filtrates of selected fungi completely suppressed the growth of the microorganisms, indicating that suppression was due to the presence of antimicrobial substances in the culture filtrate. Mode of action of these fungi against insect involves the attachment of conidia to the insect cuticle, followed by germination, cuticle penetration, and internal dissemination throughout the insect. During infection process, secreted enzymes, proteinous toxins, and/or secondary metabolites secreted by entomopathogenic fungi can be used to overcome the host immune system, modify host behavior, and defend host resources. Recently, secondary metabolites isolated from entomopathogenic fungi have been reported as potential bioactive substances. Generally, most of bioactive substances produced by entomopathogenic fungi have reported low molecular weight (lower than 1,000 g/mol) as peptide and, in contrast the high molecular weight fungal bioactive substances are rare. Most substances based on entomopathogenic fungi were shown antimicrobial activity with narrow control ranges. In our study we analyzed the antimicrobial substances having antagonistic effects to B. cinerea. Antimicrobial substances in our fungal culture filtrates showed high thermostability, high stability to proteolytic enzymes, and hydrophilicity and their molecular weights were differed from substance. In conclusion, entomopathogenic fungi showed pathogenicity against insect pests and culture filtrate of the fungi also shown to antimicrobial activity. In the future, we can use the entomopathogenic fungi and its secondary metabolites to control both insect pest control and plant pathogenic fungi simultaneously.

  • PDF

EFFECT OF CURING METHODS OF RESIN CEMENTS ON BOND STRENGTH AND ADHESIVE INTERFACE OF POST (레진시멘트의 중합방법이 포스트의 결합강도와 접착계면에 미치는 영향)

  • Kim, Mun-Hang;Kim, Hae-Jung;Cho, Young-Gon
    • Restorative Dentistry and Endodontics
    • /
    • v.34 no.2
    • /
    • pp.103-112
    • /
    • 2009
  • The purpose of this study was to compare the effect of curing methods of adhesive resins and resin cements in the root canal. Crown portions of 32 single-rooted mandibular premolars were removed. Routine endodontic treatment was done, and 9 mm deep post spaces were prepared within root canals. No.3 FRC Postec posts (Ivoclar-Vivadent AG, Liechtensteih) were cemented in the post spaces by self-(SC) or light-curing (LC) using two dual-cured adhesives (Adper Scotchbond multi-purpose plus and Exite DSC )and resin cements (RelyX ARC and Variolink II). They were assigned to 4 groups (n=8): R-SC, R-LC, V-SC, V-LC group. After stored in distilled water for 24 hours, each root was transversally sectioned with 1.5 mm thick and made three slices. The specimens were subjected to push-out test in a universal testing machine (EZ Test, Shimadzu Co., Japan) with a crosshead speed of 1 mm/min. The data were analyzed with repeated ANOVA and one-way ANOVA. Also the interface of post-resin cement and resin cement-canal wall of each group was observed under FE-SEM. When fiber posts were cemented into the root canal using total-etch adhesives, the bond strength and adaptation between post and root canal dentin was affected by curing method. Self-cure of adhesives and resin cements showed higher bond strength and closer adaptation than light-cure of them.

A Methodology to Evaluate Economic Feasibility by Taking into Account Social Costs from Automobile Exhaust Gases (자동차 배기가스로 인한 사회적 비용을 고려한 경제성 평가 방법론)

  • Cho, A-Ra;Lim, Seong-Rin
    • Clean Technology
    • /
    • v.25 no.3
    • /
    • pp.263-272
    • /
    • 2019
  • Air pollutants have a high impact on everyday life as well as on human health; therefore, new technologies such as low-emission vehicles and add-on systems for air pollutant reduction are needed for our society. However, the environmental benefits and costs of those technologies are not taken into account in existing economic feasibility assessments, which is a barrier that needs to be overcome for green technology to achieve wide dissemination and fast penetration in the market. Thus, this study develops a methodology to assess the economic feasibility of an air pollutant reduction technology by taking into account the social costs from air pollutants and carries out a case study to validate the methodology. Because the social unit costs for air pollutants have not been evaluated yet in South Korea, the methodology uses the social unit costs evaluated for the European Union that are then converted to those for South Korea based on the measuring criteria for vehicle emission gases, parity purchasing price, foreign currency exchange rate, and customer price index. The social unit costs for South Korea are used to assess economic feasibility. A case study was performed to assess the economic feasibility of a dual fuel system using diesel and compressed natural gas by taking into account social costs from air pollutants as well as economic costs. This study could contribute to assessing the true economic feasibility of green technology, projects, and policy related with air pollutant reduction.

Review of China's National Earthquake Governance and Role-Sharing (중국 국가 지진 거버넌스 및 역할분담 고찰)

  • Kim, Seong-Yong
    • Economic and Environmental Geology
    • /
    • v.54 no.1
    • /
    • pp.127-136
    • /
    • 2021
  • This study was carried out to understand China's earthquake governance and role-sharing, and to strategically use it for research cooperation in related fields with China. The characteristics of China's national earthquake governance and role-sharing are detailed in this study. First, unlike Korea, China's geoscience and earthquake research fields are separate, and are clearly distinguished from other fields of science and technology. They hold a higher status compared to other fields in China. Second, China's provincial earthquake agencies simultaneously carry out related tasks under the dual supervisory management system of the central and provincial governments. Third, the China Earthquake Administration (CEA) has the authority to do research and development, manpower training, and degree conferment, which are centered on directly affiliated institutions. Fourth, China carries out similar functions in directly affiliated institutions of the CEA and the China Geological Survey (CGS), and affiliated institutions of the Chinese Academy of Sciences (CAS), respectively. Fifth, the CEA is continuously expanding the seismic observation network that connects the vast land of the country. Sixth, China is considered to have detailed structures of earthquake-related laws and regulations. Given China's earthquake governance and role-sharing, it is considered that the possibility of success in research cooperation is high if Korea first determines whether it is under the jurisdiction of the CGS, CEA, and CAS, depending on the specific field.

Family Values and Caring Work of Single-Person Households in Ulsan: A Case Study (울산시 1인가구의 가족가치관 및 돌봄노동에 대한 사례연구)

  • Kwon, Anna
    • Journal of Family Resource Management and Policy Review
    • /
    • v.27 no.2
    • /
    • pp.35-47
    • /
    • 2023
  • The purpose of this study was to understand family changes and dynamics of and to suggest institutional/policy-level tasks for coping with them, by paying attention to changing family values of single-person households and their caring work performed in everyday life. This study selected 11 single-person households residing in Ulsan by considering their age and marital status, and analyzed their overall daily lives, family values, and the characteristics of household work and caring. The characteristics of these single-person households in Ulsan, not only showed the coexistence of "simplicity, but instability" when maintaining and living their own lives, but also showed the ambivalent characteristics of family values by showing a gap between the perception and reality of diversity. In regard to family life, the participants complained of difficulties in "caring and relationship of family of origin" and the "economic factors", and notably showed the "dual value system". For a more stable life, the single-person households were forming social networks to relieve a sense of isolation and loneliness, and to recover relationships, instead of limiting themselves to only the traditional method of family formation. Thus, it would be possible to respond to family changes when changes are promoted in each area of "the perception of life", "family life", and the "family & social relationship", and this research suggests policy-level tasks based on the results of this study.

Generation of Sea Surface Temperature Products Considering Cloud Effects Using NOAA/AVHRR Data in the TeraScan System: Case Study for May Data (TeraScan시스템에서 NOAA/AVHRR 해수면온도 산출시 구름 영향에 따른 신뢰도 부여 기법: 5월 자료 적용)

  • Yang, Sung-Soo;Yang, Chan-Su;Park, Kwang-Soon
    • Journal of the Korean Society for Marine Environment & Energy
    • /
    • v.13 no.3
    • /
    • pp.165-173
    • /
    • 2010
  • A cloud detection method is introduced to improve the reliability of NOAA/AVHRR Sea Surface Temperature (SST) data processed during the daytime and nighttime in the TeraScan System. In daytime, the channels 2 and 4 are used to detect a cloud using the three tests, which are spatial uniformity tests of brightness temperature (infrared channel 4) and channel 2 albedo, and reflectivity threshold test for visible channel 2. Meanwhile, the nighttime cloud detection tests are performed by using the channels 3 and 4, because the channel 2 data are not available in nighttime. This process include the dual channel brightness temperature difference (ch3 - ch4) and infrared channel brightness temperature threshold tests. For a comparison of daytime and nighttime SST images, two data used here are obtained at 0:28 (UTC) and 21:00 (UTC) on May 13, 2009. 6 parameters was tested to understand the factors that affect a cloud masking in and around Korean Peninsula. In daytime, the thresholds for ch2_max cover a range 3 through 8, and ch4_delta and ch2_delta are fixed on 5 and 2, respectively. In nighttime, the threshold range of ch3_minus_ch4 is from -1 to 0, and ch4_delta and min_ch4_temp have the fixed thresholds with 3.5 and 0, respectively. It is acceptable that the resulted images represent a reliability of SST according to the change of cloud masking area by each level. In the future, the accuracy of SST will be verified, and an assimilation method for SST data should be tested for a reliability improvement considering an atmospheric characteristic of research area around Korean Peninsula.

A study on ceremonial costume and Confucianism is Chosun Dynasty - Focusing on Men's Po - (조선시대(朝鮮時代) 유교사상(儒敎思想)과 의예복연구(儀禮服硏究) - 남자(男子) 포(袍)를 중심(中心)으로 -)

  • Lee, Sun-Jae
    • Journal of the Korean Society of Costume
    • /
    • v.16
    • /
    • pp.221-229
    • /
    • 1991
  • This thesis aims at reviewing the wearing aspect and formation of Chosun ceremonial dresses for meal and finding out the thought reflected by them from the standpoint that dresses themselves should be taken as one of the phenomena in culture. That is men's ceremonial costumes and confucian costumes of the royal family and the gentry family in Chosun is reviewed focused on the formation and the wearing aspect of Po, Which is a kind of them. And in the context of the phase of the times. I also considered the thoughts reflected on the clothes such as confucianism, Ying & Yang Theory, and the symbol and the thoughts of patterns in relation to the clothes. Confucian influence was the main force for the Chosun prohibitions for clothes. The major reasons for the prohibitions for clothes were as follows. First, they reflected confucian Chung myoung chooui(the principle that everything should be where it belongs). That is the prohibitions for clothes were used in the means to maintain feudalistic social order. influenced by social rank system. Second, they reflected confucian ethics in the means to recover social disciplines with the maintenance of traditional customs. This shows well in the restriction of luxurious items in dressing included the prohibitions for clothes. Third, they reflected Chosun's toadysm toward China. With the influx of Chinese style of dressing then government even changed the style of uniforms for public officials into that of Chinese resulting in dual styles of dressing. Ying & Yan Theory greatly affected the colors of Korean clothes and reflected toadysm toward China. too. The theory was embodied by prohibition of such colors for clothes as white, gray, and jade green. I reviewed the twelve patterns on Myunpok, Ten-Longivity patterns and Four-Gracious plants patterns in order to analyze the symbolism and thoughts of patterns for clothes. Nansam, Dopo, and Shimui worn by confucian scholars ensures that those clothes bears confucianism and philosopical factors. As shimui was worn by many people it appears in Chosun scholars' studies and a Chinese book called "Yeki". I reviewed the origin, procession, and ornaments of four ceremonial clothes and tried to find out the confucianism in them. First, In Kwanrei (the coming-of-age ceremony) remained ancestor worship and respect for manners. The clothes for this ceremony granted the rights and responsibilities of and adult to the wearer. The royal Kwanreipok had different dresses for each rank. As Samgapok, the crown prince wore Iksunkwan and Konryongpo for the first ritual, Wonryukwan and Kangsapo for the second, and Myunrukwan and Konpok for the third. The rank of the King's grandson was lower than the crown prince's. This example shows that Chosun people respected manners and thought the basic confucianism "God and people are equal." at the Royal court. Second, as Honreipok(wedding gown), the crown prince wore Myunrukwan and Konpok for Daereipok, Wonyukwan and Kangsapo for Napjing and Tongwoo, and Iksunkwan and Konryongpo for Chekbinui. But common people were allowed to wear an official outfit only for wedding in the means of congratulation on the most important day of their life. Wedding gowns which reflected Ying and Yang Theory emphasized the thought that union of a man and a wife is the most important event in life. Third, Sangrei(funeral) was the last ritual of a human being to send off the deceased. The mourning dresses expressed lamentation of the people left behind. Five-Dress-System for each the relative degree of familarity showed the solemnity and formality, which represented the formality of confucianism and ancestor worship. I reviewed the mourning dresses by dividing them into royal, Yangban's, and commons. They were featured by the fact that there was only one style for every walk of life. It is construed that anyone in mourning can wear the same clothes since he feels the same way regardless of his social rank. Fourth, Chereipok(sacrificial rite dresses) had different styles for each social rank. The King wore Myunpok(Kuryumyun and Kujangpok) were recorded to be worn first in the fourth year of King Taecho's ruling. The crown prince wore Palryumyun and Chiljangpok for sacrificial rite dress which was finally settled when King Sejong was in power. Common people wore Dopo, Shimui for the rite dress in the beginning of the Chosun Era and wore Dopo after Japanese invasion of Korea in 1592. In conclusion, confucianism played the main role in ceremonial dress system of Chosun and that was because it emphasized the ethics of action in life, which was different from other religions. It is true that cause-oriented thoughts and Chung myoung chooui in confucianism drove all ceremonies to extreme manners, discriminating the people who belonged to the lower social rank, and resulting in extremly luxurious life style. However, they also created a unique trend and clothes culture in the Chosun Era. I wish that this thesis provieds important information and direction for furthur studies in the future.

  • PDF

Mechanism of Catecholamine Secretion Evoked by Lithium from the Isolated Perfused Rat Adrenal Gland (흰쥐 적출관류부신에서 리튬에 의한 카테콜아민 분비작용의 기전)

  • Lim, Dong-Yoon;Kim, Cheol;Oh, Hyeong-Geun
    • The Korean Journal of Pharmacology
    • /
    • v.32 no.3
    • /
    • pp.357-371
    • /
    • 1996
  • Lithium (Li) is known to be used not only during acute manic psychosis but also acute depressive phase in manic-depression. In the present study, it was attempted to investigate the effect of lithium on catecholamine (CA) secretion from the isolated perfused rat adrenal gland and to clarify the mechanism of its action. Replacement of $Na^+$ (118.4 mM) by lithium in the normal Krebs-bicarbonate solution used to perfuse the gland produced gradually an increased response in the spontaneous catecholamine release, which was peaked at $30{\sim}60$ min after its perfusion. Li-Krebs solution was perfused into an adrenal vein for 2 hours in every experiments. Li-Krebs-evoked CA secretory responses were depressed significantly under loading with $Ca^{++}-free$ medium. This CA secretion evoked by lithium loading was also reduced markedly by the pretreatment with nicardipine ($10^{-6}$ M), TMB-8 ($10^{-5}$ M) and chlorisondamine ($10^{-6}$ M) for 20 min, respectively, while was not affected by preloading with a pirenzepine ($2{\times}10^{-6}$ M)-containing Krebs. $Na^+$ pump inhibition by pretreatment with ouabain ($10^{-4}$ M) for 20 min did make the marked depression in Li-evoked CA secretory responses. Moreover, Li-evoked CA release was also diminished markedly by preloading with tetrodotoxin ($5{\times}10^{-7}$ M)-contaming Krebs for 20 min. All these experimental results taken together suggest that lithium enhances CA secretion in a $Ca^{++}$-dependent fashion by its accumulation in the adrenomedullary chromaffin cells of the rat, and that this secretory effect may be meidated by a dual mechanism: (i) chromaffin cell depolarization and subsequent opening of voltage-sensitive $Ca^{++}$ channels and (ii) activation of a $[Li]_i-[Ca]_0$ counter-transport system.

  • PDF