• 한국임상수의학회지
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• 제37권2호
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• pp.75-81
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• 2020

The objective of the present study was to evaluate the effectiveness of autoligation techniques for castrating healthy male small breed dogs. Forty dogs were divided into four groups, with 10 in each group, based on maturity and the surgical technique used: 1) immature dogs aged less than 1 year, with autoligation of the spermatic cord via a scrotal approach (SAL) as the surgical technique (SAL-IM); 2) mature dogs aged 1 year or older, with the same SAL surgical technique (SAL-M); 3) immature dogs aged less than 1 year, with double ligation of the spermatic cord with an absorbable suture via a prescrotal approach (PDL) as the surgical technique (PDL-IM); and 4) mature dogs aged 1 year or older, with the same PDL surgical technique (PDL-M). The effectiveness of the surgical technique was evaluated by comparing the operating time and complications between these four groups. The significant decreases in operating times were found in SAL-IM and SAL-M compared with those of PDL-IM and PDL-M (p < 0.01 and p < 0.01). Regardless of maturity, the SAL surgical technique reduced operating time by approximately 69.5% compared with the PDL surgical technique. When the complication severities were scored, the results showed no significant differences among the four group. The autoligation technique for castration in healthy male small breed dogs is considered to be effective because the operating time consuming is less than conventional techniques.

• Journal of Veterinary Science
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• 제19권6호
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• pp.840-845
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• 2018

The purpose of this study was to propose a standard for differentiation between normal dogs and patients with hyperadrenocorticism (HAC) by measuring skin thickness via ultrasonography in small breed dogs. Significant changes in skin thickness of patients treated with prednisolone (PDS) or patients with HAC treated with trilostane were evaluated. Skin thickness was retrospectively measured on three abdominal digital images obtained from small breed dogs weighing < 15 kg that underwent abdominal ultrasonography. Mean skin thickness of normal dogs was $1.03{\pm}0.25mm$ (mean ${\pm}$ SD). Both the HAC and PDS groups showed significantly thinner skin than that in the normal group. Seven of the 10 HAC patients treated with trilostane had increased skin thickness. The area under the curve value of 0.807 was based on the receiver operating characteristics (ROC) curve for differentiating normal dogs from HAC patients. Sensitivity was 76% and specificity was 73% when skin thickness was less than the 0.83 mm cutoff value. In conclusion, measurement of skin thickness in small breed dogs by using ultrasonography is likely to provide clinical information useful in differentiating HAC patients from normal dogs. However, exposure to PDS, trilostane, and other conditions may have a significant effect on skin thickness.

• 한국임상수의학회지
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• 제40권5호
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• pp.330-335
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• 2023

Platelet function evaluation by PFA-100 or -200 has been known to be objective and sensitive for assessing platelet function and dysfunction of Von Willebrand Factor in humans and dogs. However, using the C/EPI cartridge in dogs is controversial. This study aimed to establish a reference range for PFA closure time in healthy small breed dogs (body weight < 10 kg) and to evaluate the effectiveness of both C/ADP and C/EPI cartridges for these dogs. Citrated blood samples were collected from 50 clinically healthy small breed dogs that were admitted for presurgical procedures or health checkups, and closure times were measured using the PFA-200. Reference ranges were determined as 42-144 s (median 67 s, mean 71.2 s, SD ± 21.2 s, 95% RI 43-140 s) , for CT-C/ADP and 41-200 s (median 87, mean 91.2 s, SD ± 31.8 s, 95% RI 44-195 s) for CT-C/EPI. The present study demonstrated that the reference ranges for PFA closure times in small breed dogs are in line with existing reference ranges. The utilization of C/ADP cartridges is the preferred choice for evaluating platelet function in small breed dogs. However, due to variable responses of epinephrine to platelet aggregation in dogs, caution should be exercised when using C/EPI cartridges.

• 한국임상수의학회지
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• 제40권6호
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• pp.414-422
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• 2023

Hearing assessment is critical in dogs and cats. Hearing loss in dogs and cats may be congenital or secondary to a central nervous system disorder or ear disease. The brainstem auditory-evoked response (BAER) test has been developed as an electrophysiological test for auditory function assessment. Modern BAER equipment is based on a computerized system. Thus, auditory function assessment can be performed using this objective, safe, and noninvasive method. No study has yet investigated the interspecies differences between BAER test results of dogs and cats. Therefore, the present study aimed to analyze the differences in BAER test results between dogs and cats. The test was conducted on four healthy adult dogs and four healthy adult cats. Regarding latency, lower values were obtained for all waveforms above 50 dB in cats compared to dogs. Regarding amplitude, cats showed higher values than dogs at intensities above 50 dB. Through a comparative analysis in this study, it was concluded that the two species had statistically significant differences. The BAER data of dogs cannot be applied to cats, and vice versa.

• 대한한의학회지
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• 제30권6호
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• pp.27-34
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• 2009

Objectives: To evaluate the acute toxic effects and approximate lethal dose of Cheonggan extracts (CGX) in SD rats and beagle dogs. Methods: Male and female rats were divided into 4 groups (Control, CGX 1250, CGX 2500, CGX 5000) respectively and male and female dogs were divided into two groups respectively (Control, CGX 5000) respectively. A single oral dose of CGX was treated to the rats and dogs. Mortality, signs of gross toxicity, and behavioral changes were observed over 14 days. All animals were observed every hour for 4 hours after administration and once a day thereafter for 14 days. Body weights were determined at $0_{th}$, $7_{th}$, and $14_{th}$ days. All surviving animals were sacrificed and necrotized. Major organs were inspected visually for gross findings. Results: No animals died in any of the groups during the experimental period (2 weeks), rats or dogs. Body weights of rats and dogs during the experiment continuously increased in all groups but there was no significant change. No abnormal clinical signs were observed for 2 weeks after a single administration of CGX in any dose group of CGX, rats or dogs. No abnormal findings in major organs were observed in any group of rats or dogs. Conclusion: CGX does not have acute toxic effects in rats or dogs. Therefore, an approximate lethal dose is assumed to exceed 5000 mg/kg in both rats and dogs.

• Parasites, Hosts and Diseases
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• 제39권3호
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• pp.227-232
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• 2001

Eight dogs were experimentally infected with Sarcocystis by oral inoculation of cardiac muscle from naturally infected cattle. The infected dogs commenced discharging of sporocysts in the feces after 10 to 12 days of inoculation, and continued until 20 and 35 days after inoculation. Three dogs were reinfected with cardiac muscle from the naturally infected cattle. Sporocysts reappeared in the feces on 12 to 13 days after reinfection. Sarcosystis sporocysts collected from the experimentally infected dogs were fed to each of the two 30-day-old Korean native calves. The infected calves remained clinically normal, except for the high fever (${\geq}{\;} 40^{\circ}C$) and decreased hematocrit values on day 30 to 40 post inoculation. Muscular cysts of Sarcocystis were found from infected calves on day 40 post inoculation. Proliferative forms of Sarcocystis were also observed in the muscle of infected calves. These results suggest that the Sarcocystis cruzi found in Korean native cattle has a 2-host life cycle with dogs as the definitive host and Korean native calves as the intermediate host.

• 한국임상수의학회지
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• 제14권1호
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• pp.65-69
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• 1997

The bone alkaline phosphatase(BALP) in 130 sera of normal dogs were assayed according to the lectin precipitation method of Rosalki and Foo. The serum BALP activities showed a wide variation as $23.27({\pm}14.73)$ IU/L in young dogs from 6weeks to 12 months old and were lower in magnitude as $9.24({\pm}3.36)$ IU/L in elder dogs from 1 years to 6years old. The serum BALP activities in normal dogs were no significant correlation in sex.

• 한국임상수의학회지
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• 제34권6호
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• pp.434-436
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• 2017

Nine dogs with history of lameness and anorexia were presented. On physical examination, all dogs had gait abnormality and six dogs had high body temperature. Their clinical signs were mostly episodic, and only non-specific symptoms were occasionally observed. Arthrocentesis was performed in all dogs, and immune-mediated polyarthritis (IMPA) was diagnosed. Definitive rheumatoid arthritis (RA) and systemic lupus erythematous (SLE) were diagnosed in one dogs, one each. Prednisolone (PDS) was chosen as the first-line therapy for all dogs, except for the one with RA. Most cases responded to PDS but some cases including those of SLE and RA were refractory to PDS. IMPA can be challenging to diagnose due to its vague symptom and is commonly implicated in 'fever of unknown origin'. Therefore, clinicians should consider IMPA as a differential diagnosis when the patient has fever with systemic, non-specific signs, such as anorexia and depression, but does not respond to antibiotics.

• Parasites, Hosts and Diseases
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• 제49권2호
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• pp.181-182
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• 2011

This study was performed to investigate the prevalence of Toxocara canis in local districts in North West Bank of Palestine. Fecal samples from 132 dogs were collected in Nablus, Tulkarm, and Jenin cities from September 2008 to April 2009 and examined for T. canis eggs with the floating technique. The overall infection rate of toxocariasis in dogs was 36.4%. The dogs less than 6 months old showed higher infection rates than those older than 12 months (p=0.04). Vigorous interventions are necessary, such as routine coprological examinations of dogs and prescription of anthelmintics to infected dogs.

• 생명과학회지
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• 제18권1호
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• pp.91-95
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• 2008

In human, sympathetic nerve blocks with local anesthetics are widely used to treat a variety of diseases in the innervating regions. However, its procedure in dogs is difficult to approach and process repeatedly because of anatomically location. Therefore, this study was designed to develop a new technique of sympathetic nerve block in beagle dogs. Fifteen healthy beagle dogs, which did not show any neurologic abnormalities and disease, were used for the study. Radiograghs were taken after injected radiopaque material mixed with 2% lidocaine at the cranial cervical ganglion and injected methylene blue using the same percutaneous technique to verify the reliability of this newly developed technique. The successful block rate of the cranial cervical ganglion block was present in 80% of all dogs and the stained cranial cervical ganglions were shown in all dogs. The results show that this new technique of the cranial cervical ganglion block is a reliable and simple method that can be used for clinical studies in dogs.