• Parasites, Hosts and Diseases
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• 제53권4호
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• pp.477-481
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• 2015

Giardia is a major public health concern and considered as reemerging in industrialized countries. The present study investigated the prevalence of giardiosis in 202 sheltered dogs using PCR. The infection rate was 33.2% (67/202); Gyeongsangbuk-do and Daejeon showed 25.7% (39/152, P<0.0001) and 56% (28/50), respectively. The prevalence of infected female dogs (46.7%, P<0.001) was higher than in male dogs (21.8%). A higher prevalence (43.5%, P<0.0001) was observed in mixed breed dogs than purebred (14.1%). Although most of the fecal samples collected were from dogs of ${\geq}1$ year of age which showed only 27.4% positive rate, 61.8% (P<0.001) of the total samples collected from young animals (<1 year of age) were positive for G. intestinalis. A significantly higher prevalence in symptomatic dogs (60.8%, P<0.0001) was observed than in asymptomatic dogs (23.8%). Furthermore, the analysis of nucleotide sequences of the samples revealed that G. intestinalis Assemblages A and C were found in the feces of dogs from Gyeongsangbuk-do and Daejeon. Since G. intestinalis Assemblage A has been known to infect humans, our results suggest that dogs can act as an important reservoir of giardiosis in Korea. Hence, hygienic management should be given to prevent possible transmission to humans.

• 한국임상수의학회지
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• 제33권2호
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• pp.81-86
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• 2016

Cystatin C is a low molecular weight 13 kilodalton protein. It is known to be a more sensitive marker of glomerular filtration rate than creatinine in humans. The purpose of the present study was to demonstrate the changes of renal markers including cystatin C according to the severity of chronic mitral valve insufficiency (CMVI) and to investigate the clinical relevance of cystatin C as an early renal marker in dogs with CMVI. A retrospective study was performed to assess renal function according to International Small Animal Cardiac Health Council (ISACHC) system classification of heart failure in dogs with CMVI. Thirty seven dogs were divided into a group 1 (healthy dogs ; n = 10), a group 2 (ISACHC I ; n = 10) and a group 3 (ISACHC II-III ; n = 17). In all dogs, serum concentrations of bun (sUr), creatinine (sCr) and cystatin C (sCys-C) were measured with an automated analyzer. In dogs with CMVI, sCys-C concentrations were significantly correlated with sCr concentrations and were independent of age, BW, SBP, and sex. Renal dysfunction tended to occur more frequently as the severity of CMVI increases. In dogs with mild CMVI, only sCys-C concentrations were statistically higher than in healthy dogs. This study demonstrates the clinical relevance of sCys-C. sCys-C may be a valuable renal marker for early diagnosis of renal dysfunction in dogs with CMVI.

• Journal of Veterinary Science
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• 제23권3호
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• pp.46.1-46.8
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• 2022

Background: Stenting is an effective treatment option for tracheal collapse in dogs. Cross-braided tracheal stents are currently the norm in veterinary medicine, but cross-and-hook braided stents have recently been adopted in human medicine. We examined whether stents manufactured using this novel braiding technique provided additional advantages for the treatment of tracheal collapse in dogs. Objectives: To evaluate the outcomes of cross-and-hook braided stent implantation in the treatment of tracheal collapse in dogs. Methods: The medical records of 22 client-owned dogs that underwent luminal placement of cross-and-hook braided Fauna Stents for the treatment of tracheal collapse between January 2018 and July 2021 were examined and data on canine signalment, clinical signs, diagnostic test results, surgical outcomes, and postoperative complications were retrieved and analyzed statistically. Results: Twenty-six stents were surgically implanted, with 20 dogs (90.9%) receiving one stent and the remaining two (9.1%) receiving two or more stents. All dogs survived the procedure. The median survival time at a median follow-up of 990 days was 879 days. At the final follow-up examination, loss or mild improvement of cough was observed in all dogs. Conclusions: Compared with conventional lumen stents, the cross-and-hook braided Fauna Stent offered a higher survival rate and improved clinical symptoms in all patients. The results of this study suggest that the Fauna Stent may be a promising treatment option for dogs with tracheal collapse.

• 한국환경과학회지
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• 제31권4호
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• pp.365-368
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• 2022

The purpose of this study was to investigate the effects of desensitization and flooding on the behavior of dogs during grooming, focusing on their response to the sound and skin stimulation while using a clipper. A total of 20 adult dogs over two years of age with complete personality formation were included in the study. Ten dogs, of which three were Bichons (average weight 5 kg), four were Poodles (average weight 5 kg), and three were Malteses (average weight 4 kg), were subjected to the desensitization process. The remaining 10 adult dogs were subjected to the flooding experiment, and were of the same breed and average weight as the adult dogs used in the desensitization process. The desensitization and the flooding were performed three times a day (approximately 1 min per session) for 10 days. For desensitization, statistical significance was observed only on the fifth day, when compared by breed (p<0.05). Overall, when compared by measurement day, the results of desensitization for Bichon, Poodle and Maltese dogs were statistically significant (p<0.05). The results for the Bichon, Poodle, and Maltese dogs that were subjected to flooding were found to be statistically significant (p<0.05). There was a significant difference in the results of the flooding on the second and ninth days (p<0.05); however, flooding had no effect on the other days (p>0.05). Desensitization using the clipper, a beauty tool, was faster than flooding in achieving stabilization. In conclusion, desensitization and flooding showed positive results on the stress relief and emotions of dogs during grooming, with respect to cosmetic fear response.

• Journal of Veterinary Science
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• 제21권1호
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• pp.16.1-16.10
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• 2020

Cancer is a major cause of death in dogs worldwide, and the incidence of cancer in dogs is increasing. The attenuated total reflection Fourier transform infrared spectroscopic (ATR-FTIR) technique is a powerful tool for the diagnosis of several diseases. This method enables samples to be examined directly without pre-preparation. In this study, we evaluated the diagnostic value of ATR-FTIR for the detection of cancer in dogs. Cancer-bearing dogs (n = 30) diagnosed by pathologists and clinically healthy dogs (n = 40) were enrolled in this study. Peripheral blood was collected for clinicopathological diagnosis. ATR-FTIR spectra were acquired, and principal component analysis was performed on the full wave number spectra (4,000-650 cm^-1). The leave-one-out cross validation technique and partial least squares regression analysis were used to predict normal and cancer spectra. Red blood cell counts, hemoglobin levels and white blood cell counts were significantly lower in cancer-bearing dogs than in clinically healthy dogs (p < 0.01, p < 0.01 and p = 0.03, respectively). ATR-FTIR spectra showed significant differences between the clinically healthy and cancer-bearing groups. This finding demonstrates that ATR-FTIR can be applied as a screening technique to distinguish between cancer-bearing dogs and healthy dogs.

• 한국임상수의학회지
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• 제20권4호
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• pp.443-448
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• 2003

본 연구는 전십자인대가 단열된 개의 슬관절액에서 tartrate-resistant acid phosphatase (TRAP) 와 cathepsin K의 변화를 알아봄으로서 십자인대에 관련된 질병 또는 십자인대 치료 실패에 따른 퇴행성관절염의의 조기 진단 및 치료에 관한 정보를 얻기 위하여 실시하였다. 실험동물로는 전방십자인대가 단열된 30두의 개와 정상 성견 8 두 그리고 어린 정상 개 9두를 사용하였다. 슬관절액 내의 TRAP 과 Cathepsin K의 변화를 확인하기 위하여 조직화학 염색과 면역조직화학염색을 실시하였다. 조직학적인 검사 결과 정상견에서는 TRAP과 Cathepsin K 세포들은 찾아보기 힘들었으나 전방십자인대가 단열된 개에 있어서는 TRAP 과 Cathepsin K 그리고 chondroid metaplasia가 중심부분에서 증가되고 있음을 관찰하였다. 이러한 결과로 보아 TRAP과 Cathepsin K 세포들은 전방십자인대가 단열 또는 단열 후 회복되는 과정에서 상호 보조적으로 관여하며 세포외 방출과 관계가 있는 것으로 생각된다.

• 한국동물위생학회지
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• 제20권1호
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• pp.95-102
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• 1997

Author investigated internal parasitism for the feces of dog's training center, breeding-dog farm, dairy farm, home by 120 indoor breeding dog and 566 outdoor one in Inchon area. This survey was done from February in 1994 to December in 1995. 1. As a result of total 686 samples, positives were 373(54.4%). Among them, indoor and outdoor breeding dogs were 21(3.1%) 352(51.3%), respectively. 2. According to breeding, it was manifested that 21samples (17.5%) of 120 indoor breeding dogs were positive, and 352 samples(62.2%) of outdoor breeding were positive. 3. The infection rate of dogs for food in dairy farm, breeding dogs in the farm, dog of training center and dog of house is high in order. 4. Infection rate of parasites in 24 dogs breeds, Mongrel dogs were 81.3%, Shepherds were 80.0%, Tosas were 78.4%, Akida and Siberian huskys were 76.2%, Jindos were 55.5%, Pointers were 50.0%, although Afghan hound, Spanial, Shin-tzu, Maltis and Buldog were examined as aparasites negative. 5. After administration with vermicide parasites infection rate were 43.0% in two months. In four months, it were 66.7%, and dogs without vermicide were 87.0%. It seemed like that further research about dosage of vermicide is needed. 6. The rate of single-infection was 37.6% and that of mixed-infection was 16.8%. Among classified 13 types, Ancylostoma caninum 35.6%, Toxocara cams 11.2%, Isospora sp 9.3%, Toxascaris leonina 5.1%, Trychuris vulpis 4.4% were investigated.

• 한국동물위생학회지
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• 제13권1호
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• pp.80-89
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• 1990

The present study was conducted in order to get the relationship of heartworm, Dirofilaria immitis and eosinophils in blood of Jindo dogs. Blood samples were taken from 141( man 31, womam 110) of yellow, 44 ( man 17, woman27) of white Jindo dogs in Jindo area. The results obtained in this study were summarized as follows : 1. There were no significant differences of the hematological values in comparison with others reported values, but the mean corpuscular hemoglobin concentration and the number of eosinophils were high in comparison with other reported values. 2. The mean values of total white blood cell count(P<0.05), neutrophil(P<0.05) and monocyte(P< 0.05) were that the yellow dogs and a tendency toward fisher values than the white dogs, but no significant differences were observed. 3. Age-related differences were detected for the total erythrocyte count(P<0.05), hemoglobin content (P<0.001), PCV(P<0.001) and the number of eosinophils(P<0.001). 4. The direct and indirect eosinophil counts were increased with age, there were no significant differences of the values between two groups. 5. Dirofilaria immitis was found in 34(18.4%), increased with age and were relatively significant differences in areas of the 185 Jindo dogs. 6. Survey for hematological values of Dirofilaria immitis infected dogs with direct and indirect method, mean values of eosinophil were 2,788/ ${\mu}l,$ 3,021/ ${\mu}$l, respectively. They showed that eosinophil had a tendency toward higher values than others, but others were no significant differences.

• 대한수의학회지
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• 제56권4호
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• pp.209-213
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• 2016

This study evaluated several known echocardiographic markers related to the assessment of severity in dogs with patent ductus arteriosus (PDA) after the closure of ductus arteriosus (DA). Forty-two dogs with patent ductus arteriosus were enrolled in this study. Evaluated echocardiographic markers were left atrial to aortic root ratio, left ventricular end-diastolic dimension to aortic root ratio, indexed left ventricular end-diastolic and end-systolic dimensions, end-diastolic and end systolic volume index, pulmonic flow to systemic flow (Qp/Qs) ratio, velocities of pulmonary regurgitant and systolic jets, pulmonary flow profiles and the presence of mitral regurgitation. Those markers were evaluated before, 1 day, and 30 days after the closure of DA. Statistically significant changes in some echocardiographic markers (i.e., Qp/Qs) were observed. Although several studies in human and dogs have evaluated the clinical outcome of PDA occlusion using several echocardiographic markers, this study has firstly evaluated all echocardiographic markers known to be useful for assessing the clinical outcome of PDA occlusion in human, and has demonstrated that those markers including the Qp/Qs and pulmonary flow profiles were useful in evaluating of clinical outcome of PDA in dogs and the reduction of LA and LV preload after ductal closure could dramatically reduce after successful ductal occlusion of PDA in dogs.

• 한국동물위생학회지
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• 제26권2호
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• pp.129-134
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• 2003

A survey of canine heartworm(Dirofilaria immitis) infections among dogs in Daefu area was performed from February 2000 to October 2002 using a microfilarial test and an antigen test(AGEN$^{TM}$ Canine heartworm). The infection rate of 220 dogs(96 males, 124 females) was 23.2%(51/22) by the microfilarial test, but was 23.6%(52/220) by the antigen test, revealing that 1 of 52 antigen-positive dogs were microfilaria-negative in the peripheral blood. All dogs that were microgilaria-positive were also antigen-positive. The infection rates of heartworm in dogs at the age of < 1, 1-3, 4-6, 7-11 and 12-15 years were 2.7%, 17.4%, 41.0%, 42.9% and 57.1%, respectively. Based on the fact that the antigen test is more accurate than the microfilaria test. The infection rates of heartworm in dogs by housing of indoor and outdoor were 6.9% and 46.4%, respectively. Based on the fact that outdoor housing is more infectious than indoor housing.