• 대한한방내과학회지
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• 제11권1호
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• pp.93-107
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• 1990

Studies on diagnosis and treatment of tumor . abscess . ulcer in intestinal carbuncle were carried out. The result of studies were summerized as follows: 1. By Nai-Gyung carbuncle-tumor arose from disharmony between nutrient and defensive because of cold, abscess arose from fever victory between cold and fever, ulcer arose from decreasing function of Bi-Kam year. By latter literature Bi-Kam year could be interpreted that spleen stomach was invaded evil influence from unattainable vital force of the earth. 2. Sites of intestinal carbuncle were large intestine, small intestine, intestinal inside or outside between large and small intestine, Intestinal carbuncle was common name of a disease about large intestinal carbuncle, small intestinal carbuncle, pelvic intestinal carbuncle, shrink leg intestinal carbuncle etc.. Pain appeared Chunchu-Hyul in large intestinal carbuncle, and Gwanweon-Hyul in small intestinal carbuncle. 3. On abdominal diagnosis tumor had indistinct pain of Gwanweon Chunchu, edema and heary feeling in low abdomen, no excessive pain by hand press and intestinal boiling sound. In abscess pain descended from right side of low abdomen to huckle, and there was rejection against press, feeling about fever,water sound with flank movement. In ulcer hand approach was difficult since excessive pain diffuse to whole abdomen, and perforating ulcer sometimes caused a serious symptom of umbilical pus. 4. On fecal and urinary diagnosis in tumor urine was yellowish red pollakiuria like gonorrhoea and occasional constipation. In abscess uncomfortable rough pain short red early urine like gonorrhoea appeared during urination, and constipation with stinging pain appeared during defecation. In ulcer red rough pyuria appeared, and stinging and pain with puruloid blood appeared during defecation. 5. On treatment in tumor Daiwhang-Tang Daisenggi-Tang Dangui-Jun by dissipation method, calming down method, interior reliance maturation method, in abscess Mokdan-San Euiiin-Tang Jeokduiin-Tang by the method of water repelling pus discharge, acute breaking, in ulcer Takridanggui-Tang Paljin-Tang Bojungikki-Tang were each used by the method of interior reliance, virulence astriction, supplement vital force and blood, supplement spleen stomach. 6. On treatment patient may have to be careful of excessive moving and suprising anxiety. Abuse of acupuncture and moxibustion made patient worse, misuse of analgesics purgative intestinal irrigation etc. could provoke difficult diagnosis and perforation. So you must treat after exact diagnosis. 7. Prognosis of ease tumor ease abscess ease ulcer and ease astriction was good. If the intestinal carbuncle were not to promote to abscess and ulcer for a long time, its prognosis was bad and it could metastasize to cancer because of dark purple with hardness. So tumor abscess ulcer in intestinal carbuncle may be significant of precancerous lesion.

• 한국치위생학회지
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• 제10권3호
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• pp.541-553
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• 2010

Objectives : The purpose of this study was to examine the use of dentifrice for children, the state of dentifrice for children on the market and the relationship between the bore of dentifrice and the amount of dentifrice used in an effort to provide parents, main consumers of dentifrice for children, with the right information on dentifrice. Methods : Data on the use of children's dentifrice were gathered by investigating parents in Seoul and Gyeonggi Province in July and August, 2009. The selected parents had children aged one to five in Western age. Results : 1. As to the purchase of dentifrice for children, the largest group (75.9%) were aware of the name of the toothbrush used by their children, and the greatest group (97.3%) bought the toothbrush on behalf of them. Advertising was the most dominant source of information on the choice of dentifrice (51.8%), and non-professionals were the most common providers of information on that (55.9%). 2. The amount of dentifrice used at a time was a mean of $0.467{\pm}0.270g$. There was a wide disparity in that aspect from a low of 0.100 to 1.900g. As to the influence of the size of the bore of dentifrice, the greatest amount of dentifrice was used ($0.670{\pm}0.306g$) when the bore of dentifrice was 9 mm in size, and the bore size 9 mm was significantly different from the size 3 mm and 6 mm in that aspect (p<0.001). 3. There was one kind of imported dentifrice for children on the market. Concerning the fluoride ingredient of dentifrice, the biggest number of dentifrice contained MFP only. As to the size of the bore of dentifrice, there was a difference of 3 to 9 mm. Most of dentifrice for children included the pictures of particular characters. Conclusions : The above-mentioned findings illustrated that there is a serious concern for the intake of fluoride among infants and preschoolers, it's needed to pay careful attention to the use of dentifrice. Dentifrice for children should be manufactured in consideration of the relationship between the size of the bore and the amount of dentifrice used.

• 한국잡초학회지
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• 제17권1호
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• pp.66-70
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• 1997

(주)LG화학에서 개발중엔 LGC-40863은 벼에 대해 높은 안전성을 보이며 피 등 여러 잡초를 방제하는 신규제초제이다. LGC-40863은 관련 제초제나 식물에서의 효과 발현 증상으로 부터 acetolactate synthase(ALS)를 저해하는 것으로 추정된다. 본 연구에서는 LGC-40863의 ALS에 대한 영향을 알아보기 위하여 벼와 피로부터 추출한 ALS를 사용하여 $I_{50}$값과 효소반응속도를 조사하였다. LGC-40863의 $I_{50}$값은 14(벼), 16mM(피)였고, 대조약제로 사용한 imazapyr와 chlorsulfuron의 $I_{50}$값은 각각 12-15mM, 0.03-0.04mM였으므로 LGC-40863의 $I_{50}$값은 imazapyr와 유사하고 chlorsulfuron에 비해서는 약 400배 정도 높았다. 그리고 세 가지 약재 모두 벼와 피 간의 감수성 차이는 크지 않았다. 효소반응속도 면에서 살펴보면, LGC-40863은 벼와 피 모두 pyruvate에 대해 noncompetitive inhibition을 나타내었으며, chlorsulfuron과 imazapyr는 벼에서 각각 noncompetitive와 uncompetitive inhibition을 하는 것으로 나타났으므로 LGC-40863은 chlorsulfuron과 저해유형이 비슷하였다.

• 식물분류학회지
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• 제43권4호
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• pp.319-331
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• 2013

Koidzumi Gen'ichi(1883-1953), Ohwi Jisaburo(1905-1977), Kitamura Siro(1906-2002) 등이 1930년에서 1935년에 걸쳐 약 5년간 실시한 한반도 식물 채집에서 얻어진 식물표본레이블에 기록된 내용을 바탕으로 당시의 채집행적을 정리하였다. 일본 교토대학(京都大學, Kyoto University; KYO)에 소장된 표본은 전체 2,000 점으로 다양하지만, 대부분은 채집자와 간략한 채집지명이 한자, 일본어 혹은 지역 방언으로 기록되어 있다. 교토대학였던 Koidzumi(小泉)는 주로 1932년, 1933년, 1935년의 방학동안인 7-8월에 한반도 남부의 제주도와 경상북도, 전라북도 지역과 북부의 금강산, 함경북도, 평안북도, 황해도 등에서 식물 채집을 하였다. Ohwi(大井)는 1930년과 1932년 3달 동안 주로 기존 채집자들이 시도하지 않은 지역인 함경북도의 경성군, 부령군, 회령군, 무산군과 함경남도 장진군, 신흥군과 함께 금강산에서 채집하고, 1935년에는 지리산, 제주도 등 한반도 남부지역에서 주로 채집하였다. Kitamura(北村)는 1930년과 1932년, 1935년에 한반도 채집을 실시하였으며 제주도와 금강산, 함경남도의 원산 및 개마고원 일대의 채집 기록이 남아 있다.

• 한국한의학연구원논문집
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• 제2권1호
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• pp.381-401
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• 1996

The diagnostic requirements were suggested and explained regarding the systems of differentiation of syptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : -differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to reletive excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) -differentiation of diseases according to pathological changes of the viscera and their interrelation(臟腑辨證) -analysing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following odor : another name(異名), notion of diagnosis parrern(證候槪念), index of differentiation of syptoms and sings(辨證指標), the main point of diagnosis(診斷要點), analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a wayof curing a diseases(治法), prescription(處方) , herbs in common use(常用藥物), dieases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

• 한국가금학회지
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• 제34권1호
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• pp.23-29
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• 2007

본 연구는 희토(rare earth RE)와 Chlortetracycline (CTC)의 육계사료에 대한 첨가 효과를 구명하고자 실시하였다. 실험은 pen별 평균 개시시 체중이 비슷하도록 15수씩 평사로 배치하여 4처리구 4반복으로 희토와 항생제-CTC, 그리고 두 가지 혼용였을 경우의 효과를 관찰하고자 0, RE 100 ppm, CTC 200 ppm, RE100 ppm+ CTC200 ppm으로 하였다. 증체량, 사료 섭취량, 사료 요구율이 실험 기간중에 조사 되었으며, 실험 종료후 도살하여 체중에 대한 간 및 복강 지방의 비율과 장내미생물의 변화를 조사하였다. 시험 결과, RE 첨가구가 대조구보다 높은 증체량을 나타냈고(P<0.05), 사료 섭취량은 대조구에 비해 현저히 낮았으며(P<0.05), 사료 요구율도 대조구에 비해 16.08% 개선된 효과를 나타냈다(P<0.05). 생체중에 대한 복강지방의 비율도 RE 첨가구가 대조구 뿐만 아니라 기타 처리구에 비해서도 현저히 감소되었다(P<0.05). 생체중에 대한 간장 무게의 비율은 모든 처리구가 대조구와 비슷한 수준을 보였다. 장내미생물은 회장과 맹장의 미생물에 대한 관찰 결과, 희토첨가로 총 균수와 E. coli의 증식을 현저하게 억제되었으며(P<0.05), Salmonella는 수가 감소되는 경향을 보였으며, Lactobacillus의 수는 차이가 없었다. 이러한 결과 희토는 육계사료에서 항생제를 대체할 가능성을 보였으며, 희토의 첨가로 생산성이 개선되고 복강 지방 감소되는 경향을 보였으며, 장내 병원성 미생물을 억제하는 결과를 보였다.

• 한국동물위생학회지
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• 제36권4호
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• pp.233-242
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• 2013

The genus Taraxacum, known by the common name Dandelion, is a medicinal herb in the family Asteraceae. It has been traditionally used as a folk medicine for the treatment or prevention of various diseases due to its anti-inflammatory and anti-oxidative properties. In this study, we attempted to evaluate protective effects of Dandelion related with anti-oxidative activity to Thioacetamide (TAA)-induced liver damage. 36 rats were randomly assigned to six experimental groups : Control, Dandelion water extract (DWE), TAA, TAA&DWE 300, TAA&DWE 600, TAA&DWE 1,200 groups. Rats in DWE and TAA&DWE groups were pretreated with DWE (300, 600 or 1,200 mg/kg BW) by gavage for 7 days. All rats were treated intraperitoneally with TAA (200 mg/kg BW) or normal saline at 12 hours after last oral administration and sacrificed at 12 hours after last treatment. Levels of WBC and Neutrophil count were significantly decresed in TAA&DWE 1,200 group compared with that in TAA group (P<0.05). In TAA&DWE 600 and TAA&DWE 1,200 groups, serum AST, ALT, GGT levels were lower than TAA group (P<0.05). The serum TG level was significantly elevated in TAA&DWE groups compared with those in TAA group. Liver tissues from TAA group showed extensive histopathological changes, characterized by moderate or severe hepatocytes degeneration, inflammatory cell infiltration, and congestion. In the TAA&DWE group, The severity of histopathological lesions were decreased compared to those in the TAA group. The MDA concentration was significantly decreased and GSH content was significantly increased in the TAA&DWE 1,200 group compared to those in the TAA group. GR, CAT and GST activities in the TAA&DWE 1,200 group were significantly increased compared to those in the TAA group.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제46권5호
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• pp.341-347
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• 2020

Objectives: Oral squamous cell carcinoma (OSCC) is one of the most common types of head and neck cancer. MicroRNAs, as new biomarkers, are recommended for diagnosis and treatment of different types of cancers. Bevacizumab, sold under the trade name Avastin, is a humanized whole monoclonal antibody that targets and blocks VEGF-A (vascular endothelial growth factor A; angiogenesis) and oncogenic signaling pathways. Materials and Methods: This study comprised 50 cases suffering from OSCC and 50 healthy participants. Peripheral blood samples were collected in glass test tubes, and RNA extraction was started immediately. Expression levels of miR-155, miR-191, and miR-494 biomarkers in the peripheral blood of OSCC-affected individuals and healthy volunteers in vivo were evaluated using real-time PCR. The influence of Avastin on the expression levels of the aforementioned biomarkers in vitro and in the HN5 cell line was also investigated. Results: Expression levels of miR-155, miR-191, and miR-494 in the peripheral blood of individuals affected by OSCC were higher than in those who were healthy. Moreover, Avastin at a concentration of 400 μM caused a decrease in the expression levels of the three biomarkers and a 1.5-fold, 3.5-fold, and 4-fold increase in apoptosis in the test samples compared to the controls in the HN5 cell line after 24, 48, and 72 hours, respectively. Conclusion: The findings of this study demonstrate that overexpression of miR-155, miR-191, and miR-494 is associated with OSCC, and Avastin is able to regulate and downregulate the expression of those biomarkers and increase apoptosis in cancerous cells in the HN5 cell line.

• 기본간호학회지
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• 제2권1호
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• pp.45-53
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• 1995

In order to nursing practice of the patient in Oriental medicine, it is suggested that the fundamental recognition of Oriental medicine should be preceded. It is, however, difficult that we comprehend Oriental medicine generally since it is different from Western medicine in the point of th symptom. We have thought that is to be carried out to select and analyze a disease by the sense of Oriental medicine for the establishment of Oriental medical nursing. So we have tried out the analysis of Tae-Yang In view of the results so far achieved, it has been suggested that Tae-Yang Symptom applies to the first step of Sanghan Yug Kyung Symptom and consists of Palsy, Sanghan, Onbyung, Dropsy, and Congestion. In the Oriental medicine, Tae-Yang Symptom is recognized to be concerned with a common cold and the respiratory, renal and hepatic diseases. In the points of Orintal medicine, it is noticed that Tae-Yang Symptom is caused by the wind and cold evil, is related to human resisting force, and is fused with each other. And the treatment of Tae-Yang Symptom is various by the cause and the pathological mechanism. In the points of Western medicine. it is difficult to comprehend that various disease germs revolving each disease are implied by identical symptom. The summary of this study are as follows ; 1. In the outer-caused diseases. so called Tae-Yang Symptom, it is an important index to the patient's resisting force and the type of a disease whether he sweats, chills and the pulse is tense or not. 2. The treatments are various according the body's resisting force and the type of symptoms; harmonizing Yung & Wee(調榮衛) to Weaknees of surface(表虛證), sudorifics flourishing of evils(表實證), and antifebriles to On-byung(溫病). 3. If Tae-Yang Symptom is not cured, it progresses to develop complications ; Dropsy(蓄水) & congestion(蓄血), the former brings about renal diseases and the latter hepatic diseses. According to the resuslts mentioned above, we have come to the conclusion that the Oriental - medical nursing must emphasis the body's sesiting force and the type of symptoms rather than the name of a disease.

• 복식
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• 제67권2호
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• pp.101-115
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• 2017

Ancient documents, characters, and relics are the utmost important materials when it comes to researching ancient clothing. Of these, the ancient characters explain the contents of the time, which makes it an objective historical record. China has hieroglyphics, such as oracle bone inscription and bronzeware script, which existed in Sang[Eun] Ju era. This character is formed by a simple line and detailed drawing, showing the object or the concrete form and characteristics, so the reader can understand the meaning. Oracle bone inscription and bronzeware script, which are written in pictograph, include contents that help to grasp the original shape and form of ancient official hats. Chinese characters Geon(巾, 건) Byun(㝸, 변) Myun(免, 면) Mo(冒, 모) Ju(冑, 주) and Kwan(冠, 관), which are the names of the official hats, have been researched, and Mi(美, 미) Ryung(令, 령) Wang(王, 왕) and Hwang(皇, 황), which are the characters related to the official hats, have been studied. Geon(巾, 건) switched its form from shape of material around waist to wraping wearer's head. Byun(㝸, 변) is a hat with decoration, and Myun(免, 면) is in form of a helmet with ornaments. Mo(冒, 모) in bone script looks like a hat with decorations on each sides, but in bronzeware script, it is more like a simple round hat Ju(冑, 주) covers one's head and has decorated ornaments, and The Kwan(冠, 관), which is now a common name of official hats, is not shown in oracle bone inscription or bronzeware script, It might have been used later than the other two types of hats. As for the related Chinese characters, Mi(美, 미) is in the shape of a feather decoration, Ryung(令, 령) is similar in shape to the letter 'A', and Wang(王, 왕) is in shape of simple hat from 령 with decorations. Hwang(皇, 황) is like a Wang(王, 왕) hat, but with fancier decorations. Oracle bone inscription and bronzeware script show the original form and shape of ancient hats.