• The Journal of Korean Medicine
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• v.41 no.3
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• pp.1-8
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• 2020

Objectives: This paper aims to investigate the Donguibogam-based pattern diagnosis by applying natural language processing and machine learning. Methods: A database has been constructed by gathering symptoms and pattern diagnosis from Donguibogam. The symptom sentences were tokenized with nouns, verbs, and adjectives with natural language processing tool. To apply symptom sentences into machine learning, Word2Vec model has been established for converting words into numeric vectors. Using the pair of symptom's vector and pattern diagnosis, a pattern prediction model has been trained through Logistic Regression. Results: The Word2Vec model's maximum performance was obtained by optimizing Word2Vec's primary parameters -the number of iterations, the vector's dimensions, and window size. The obtained pattern diagnosis regression model showed 75% (chance level 16.7%) accuracy for the prediction of Six-Qi pattern diagnosis. Conclusions: In this study, we developed pattern diagnosis prediction model based on the symptom and pattern diagnosis from Donguibogam. The prediction accuracy could be increased by the collection of data through future expansions of oriental medicine classics.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.13 no.1
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• pp.72-80
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• 2009

Objective: We performed this study to check relationship of Cold-Heat attribute analyzed quantitatively by questionnaire with acoustic analysis index. Method : We checked a questionnaire composed of 15 items about the contents of Cold-Heat and asked 83 subjects to answer in the form Likert-like 7-points score. And then, we extracted Cold-Heat attribute from heat score, cold score, heat index and cold index. we measured the acoustic analysis indexes of cardinal vowels by Dr. speech program. Afterward, the data were analyzed by correlation analysis. Results : All cardinal vowels is positive correlated with cold score, heat score and cold index. NNE of vowel /a/ is negative correlated with cold index. Shimmer and F0 tremor of vowel /e/ is negative correlated with cold index. Jitter of vower /u/ is positive correlated with Cold score.

• Tuberculosis and Respiratory Diseases
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• v.82 no.4
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• pp.269-276
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• 2019

Idiopathic interstitial pneumonia (IIP) is a histologically identifiable pulmonary disease without a known cause that usually infiltrates the lung interstitium. IIP is largely classified into idiopathic pulmonary fibrosis, idiopathic non-specific interstitial pneumonia, respiratory bronchiolitis-interstitial lung disease (ILD), cryptogenic organizing pneumonia, desquamative interstitial pneumonia, and acute interstitial pneumonia. Each of these diseases has a different prognosis and requires specific treatment, and a multidisciplinary approach that combines chest high-resolution computed tomography (HRCT), histological findings, and clinical findings is necessary for their diagnosis. Diagnosis of IIP is made based on clinical presentation, chest HRCT findings, results of pulmonary function tests, and histological findings. For histological diagnosis, video-assisted thoracoscopic biopsy and transbronchial lung biopsy are used. In order to identify ILD associated with connective tissue disease, autoimmune antibody tests may also be necessary. Many biomarkers associated with disease prognosis have been recently discovered, and future research on their clinical significance is necessary. The diagnosis of ILD is difficult because patterns of ILD are both complicated and variable. Therefore, as with other diseases, accurate history taking and meticulous physical examination are crucial.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.5 no.1
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• pp.108-115
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• 2005

Inherited metabolic diseases (IMD) comprise a large class of genetic diseases involving disorders of metabolism. The majorities are due to defects of single genes that code for enzymes that facilitate conversion of various substances into others. Because of the multiplicity of conditions, many different diagnostic tests are used for screening of IMD. Molecular genetic diagnosis is the detection of pathogenic mutations in DNA and/or RNA samples and is becoming a much more common practice in medicine today. The purpose of molecular genetic testing in IMD includes diagnostic testing, pre-symptomatic testing, carrier screening, prenatal diagnosis, preimplantation testing, and population screening. However, because of the complexity, difficulty in interpreting the result, and the ethical considerations, an understanding of technical, conceptual, and practical aspects of molecular genetic diagnosis is mandatory.

• Korean Journal of Oriental Medicine
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• v.12 no.2 s.17
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• pp.93-101
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• 2006

Pulse feeling is one of the most important diagnosis method in Oriental medicine. But it is not easy to make an objective and standardized diagnosis. In this study, we found how to quantify diagnosis. Specially dally the high practicality in clinic, we search some parameters especially well-related to floating and sinking pulse by statistic analysis. By extension, we find the pulse patterns of the floating and sinking pulse. We choose 15 subjects diagnosed as floating pulse and 15 subjects diagnosed as sinking pulse by oriental doctors. And their pulse signals were acquired by Pulse analyzer which has piezoresistive pressure sensor. For the quantification of the floating and sinking pulse, at first, we examined the parameters which were highly correlated with oriental doctor's diagnosis. And then we derived pulse patterns of the floating-sinking pulse from preprocessed signal and its ensemble average. We also looked trend variation (PH-Curve) between contact and pulse pressure. As a result, statistically there is the biggest difference between contact pressure, the maximum pulse pressure, diastolic area (Ad) and floating and sinking data. Through the PH-Curve, which represented the relationship between contact and pulse pressure, we could divide the floating and sinking pulse clearly. As a basic research of pulse diagnosis algorithm, we can contribute to select essential parameters in diagnosis algorithm And using these diagnosis method, we expect to find typical pulse patterns and some useful parameters about other pulses like slow/rapid, large/fine pulse and so on. We hope that this study will contribute pulse objectification.

• The Journal of Korean Medicine
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• v.31 no.5
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• pp.41-59
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• 2010

Objective: Headache is one of the most common symptoms in primary medical care. The purpose of this study was to support medical treatment by consideration of a new CTTH (chronic tension-type headache) oriental medical diagnosis index. Methods: An Oriental medical diagnosis questionnaire was administered to a CTTH group, migraine group and normal group. The result was classified by using LDA, CART, factor diagnosis and tested in comparison with the original diagnosis. Also, weighting method based on expert opinions was done. Results: 1. The result analyzed by using LDA has an accuracy of 93.9% in comparison with the original diagnosis. 2. High accuracy showed when the test was performed with about 35 significant questions and four questions selected based on SPSS Wilks' lambda. 3. There was accuracy of 90.9% when differentiation was performed by using CART compared with original diagnosis. 4. 10 factors has a high initial value after factor analysis, consisting of questions to the similar differentiation. 5. Diagnosis formula of headache was made by using weighting method based on expert opinions. Conclusion: Oriental medical diagnosis questionnaires make it possible to classify headaches significantly. The study about weighting method of CTTH can make it possible to classify symptoms more accurately.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.5
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• pp.950-957
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• 2009

The purpose of this study was to develop generalized validity evaluation indexes for the Sasang type diagnostic test. As a generalized evaluation index for Sasang type diagnostic test, Generalized Squared Correlation (GC2), Mutual Information (I) and Mutual Information Coefficient (IC) as overall validity index, and Correlation Coefficient (C) and Mutual Information Contribution (ID) as type-specific validity index were suggested and the practicability of these indexes was assessed along with Percentage Correctly Predicted (PCP), adjusted PCP, type-specific sensitivity and type-specific specificity which was proposed previously. The usefulness of the nine validity indexes was examined using previously reported data and three mock Sasang type diagnosis results. We demonstrated here that the PCP is not adequate for the analysis of validity. We also showed that our validity index is recommendable for the comparison and improvement of Sasang type diagnosis. The generalized validity analysis of Sasang type diagnosis can provide a guideline for the development of new Sasang type diagnosis or pattern identification. The working sheet for calculating validity indexes can be acquired at http://www.sasangtypology.org/validity.

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.2
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• pp.29-49
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• 2019

Objectives: This study was a methodological study to verify the reliability and validity and to make a diagnosis of a diagnostic tool for climacteric and postmenopausal syndrome pattern identification (CaPSPI). Methods: This study was conducted from June 1, 2018 to October 18, 2018 with ${{\bigcirc}{\bigcirc}}$ University Korean Medicine Hospital IRB's approval (2018-3). To make a diagnosis using CaPSPI, we decided the cut-points for the tool. Three professors of ${{\bigcirc}{\bigcirc}}$Korean Medical University conducted pattern identification diagnosis. The result is marked from 0 to 3, 0 is 'No', 1 is 'Slightly Yes', 2 is 'Yes' and 3 is 'Very Yes'. And if two or more professors' diagnoses are the same, we took the diagnoses as a diagnostic criteria. The decision of pattern by three experts converted to 0-1 scores in two ways. In "method 1", if the diagnosis was zero points, the score was 0 (have no such identification), and the rest was 1 (have such identification). In "method 2", if the diagnosis was zero or 1 point, the score was 0, and the rest was 1. After that, intraclass correlation was calculated for experts agreement. And logistic regression was conducted. A response variable was the results of the experts' diagnosis and an explanatory variable was the results of the pattern identification diagnostic tool. Results: The diagnosis of the three experts showed excellent concordance of more than 0.794 and showed a significant correlation with the diagnostic tool. Both 'Method 1' and 'Method 2' showed statistically significant effects with the diagnosis of 3 experts and the results of the diagnostic tool. The frequency of cumulative pattern identification diagnosis in 'Method 1' and 'Method 2' were found to be 578 occasions and 203 occasions, respectively. The average number of pattern held by participants in 'Method 1' and 'Method 2' were found to be 5.26 and 1.85, respectively. In both "Method 1" and "Method 2," the yield frequency of liver qi depression was the highest, and the frequency of kidney yin deficiency and liver-kidney yin deficiency was relatively high. Conclusions: Based on the above results, it is thought that, in diagnosis using CaPSPI of menopausal women, 'method 1' could be used for the health diagnosis and prevention, 'method 2' could be used for the pattern diagnosis. On the conclusion, CaPSPI is thought to be available for pattern diagnosis of menopause women.

• Journal of Acupuncture Research
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• v.21 no.1
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• pp.21-32
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• 2004

Objective: A study on $\ll$Lingchui, 靈樞 Weiqi, 衛氣$\gg$ which descripted Twelve meridian Biaoben(標本) pulse diagnosis method. Methods: A study on Twelve meridian Biaoben(標本) pulse diagnosis method which has the cognizance of Biaoben(標本) on upper and low twelve meridian as linear upper and low pulse diagnosis point. Results: Twelve meridian Biaoben(標本) pulse diagnosis method is derived from using each twelve meridian pulse diagnosis and it can be explained that the ben(本) pulse point on wrist ankle and the biao(標) pulse point on thorax axillary neck head face correspond to upper and low part of meridian for diagnosis and treatment which become the theory of "treat upper disease on low part, treat low disease on upper part". Conclusions: Twelve meridian Biaoben(標本) pulse diagnosis method started confirming the general concept of Jue-symptom(厥症) and Jue-symptom(絶症) and developed upper and low pulse diagnosis point or acupuncture point to treatment.

• Hip & pelvis
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• v.35 no.1
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• pp.1-5
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• 2023

Piriformis syndrome is a common differential diagnosis related to sciatica. The following review provides a concise synopsis of the diagnosis, management, history, and alternatives to diagnosis of piriformis syndrome. A search of the literature for research articles related to piriformis syndrome and associated differential diagnosis of sciatica was conducted. A thorough review of the included articles found that the condition known as piriformis syndrome is over-diagnosed and that potential anatomic and biomechanical variations originating in the pelvic region might be related to the complaint of sciatica. The criteria for diagnosis are based on findings from both physical examination and radio imaging. Piriformis syndrome resembles a variety of clinical conditions; therefore, conduct of future studies should include development of a validated method for evaluation as well as clinical criteria for diagnosis of piriformis syndrome.