• Korean Journal of Oriental Medicine
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• v.15 no.2
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• pp.93-100
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• 2009

Recently, there have been emerging research activities in classifying the Sasang constitution objectively by machine-based methods. The concordance rate of the classification by the pulse wave features was, however, only around 50% up to now. In this paper, we introduce a novel classification algorithm that can promote the accuracy substantially at the expense of the non-classifiable subgroup as a byproduct. For instance, with the pulse wave features alone, we show that female/male subject group in their 20s can be classified into the Sasang constitution group with the concordance rate of 68.4%/65.5% for a subgroup of 57/29(31%/15%) subjects out of 184/195, by leaving the other subjects as the non-classifiable group. Next, we show that the pulse diagnosis has been used only as a supportive tool in determining one's constitution, and consequently the accuracy of the concordance ratio by the pulse wave features alone cannot exceed a finite value, which we estimate to be about 60%.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.19 no.1
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• pp.1-10
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• 2015

Objectives The purpose of this study was to survey the status of clinical use of a computerized tongue diagnosis system (CTDS) Methods We searched domestic/international articles using the CTDS from online medical databases including OASIS, NDSL and pubmed. We selected articles on clinical application or reliability of CTDS but excluded articles on mechanical design or software programming for developing a new CTDS. Finally we found 15 articles and classified the articles according to the study purpose. Results Out of the 15 articles, 8 were focused on the clinical application including halitosis, cold/heat syndrome, lung cancer, xerostomia etc. Other 5 articles were aimed at evaluating and improving reliability of CTDS. The other 2 articles were studied for development of differential diagnostic criteria on tongue coating thickness. Conclusion We found out that until now the researches on clinical application of CTDS mainly had been performed for producing a variety of CTDSs. Considering the importance of the tongue color in the traditional Korean medicine, we suggest that at first standard operating procedure for CTDS be developed and researches to develop differential diagnostic criteria on tongue body/coating color be performed and then explore its applications.

• Parasites, Hosts and Diseases
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• v.58 no.5
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• pp.551-558
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• 2020

The flaviviruses are small single-stranded RNA viruses that are typically transmitted by mosquitoes or tick vectors and are etiological agents of acute zoonotic infections. The viruses are found around the world and account for significant cases of human diseases. We investigated population of culicine mosquitoes in central region of Korean Peninsula, Incheon Metropolitan City and Hwaseong-si. Aedes vexans nipponii was the most frequently collected mosquitoes (56.5%), followed by Ochlerotatus dorsalis (23.6%), Anopheles spp. (10.9%), and Culex pipiens complex (5.9%). In rural regions of Hwaseong, Aedes vexans nipponii was the highest population (62.9%), followed by Ochlerotatus dorsalis (23.9%) and Anopheles spp. (12.0%). In another rural region of Incheon (habitat of migratory birds), Culex pipiens complex was the highest population (31.4%), followed by Ochlerotatus dorsalis (30.5%), and Aedes vexans vexans (27.5%). Culex pipiens complex was the predominant species in the urban region (84.7%). Culicine mosquitoes were identified at the species level, pooled up to 30 mosquitoes each, and tested for flaviviral RNA using the SYBR Green-based RT-PCR and confirmed by cDNA sequencing. Three of the assayed 2,683 pools (989 pools without Anopheles spp.) were positive for Culex flaviviruses, an insect-specific virus, from Culex pipiens pallens collected at the habitats for migratory birds in Incheon. The maximum likelihood estimation (the estimated number) for Culex pipiens pallens positive for Culex flavivirus was 25. Although viruses responsible for mosquito-borne diseases were not identified, we encourage intensified monitoring and long-term surveillance of both vector and viruses in the interest of global public health.

• Clinical and Experimental Reproductive Medicine
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• v.35 no.1
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• pp.19-38
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• 2008

• The Journal of the Society of Korean Medicine Diagnostics
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• v.11 no.1
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• pp.25-47
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• 2007

Background and Purpose: There was seldom study about method that diagnose 8 Constitution beside method of pulse diagnosis in 8 Constitution Medicine. Objectives: This study is to make out check list for 8 Constitution Medicine Diagnosis Expert System Development used CBR(Case based Reasoning). Methods: Review of literatures about special quality element of 8 Constitution and supplement learning advice of 8 Constitution Medicine Experts constructed knowledge base. And then, knowledge base divided through AHP(Analytic Hierarchy Process), and made out check list with this. Results: Knowledge base based on special quality element of 8 Constitution was divided by 5 greate classification and 25 bisection kind, and check list consisted of 251 item was made out through this. Conclusion: Based on this research, cases necessary to make 8 Constitution Medicine Diagnosis Expert System can be gathered through check list, and further study for 8 Constitution Medicine Diagnosis Expert System Development used CBR(Case based Reasoning) is needed to supplement this research.

• Journal of Preventive Medicine and Public Health
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• v.52 no.3
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• pp.179-187
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• 2019

Objectives: In the USA, certain races and ethnicities have a disproportionately higher gastric cancer burden. Selective screening might allow for earlier detection and curative resection. Among a USA-based multiracial and ethnic cohort diagnosed with non-cardia gastric cancer (NCGC), we aimed to identify factors associated with curable stage disease at diagnosis. Methods: We retrospectively identified endoscopically diagnosed and histologically confirmed cases of NCGC at Mount Sinai Hospital in New York City. Demographic, clinical, endoscopic and histologic factors, as well as grade/stage of NCGC at diagnosis were documented. The primary outcome was the frequency of curable-stage NCGC (stage 0-1a) at diagnosis in patients with versus without an endoscopy negative for malignancy prior to their index exam diagnosing NCGC. Additional factors associated with curable-stage disease at diagnosis were determined. Results: A total of 103 racially and ethnically diverse patients were included. Nearly 38% of NCGC were stage 0-Ia, 34% stage Ib-III, and 20.3% stage IV at diagnosis. A significantly higher frequency of NCGC was diagnosed in curable stages among patients who had undergone an endoscopy that was negative for malignancy prior to their index endoscopy that diagnosed NCGC, compared to patients without a negative endoscopy prior to their index exam (69.6% vs. 28.6%, p=0.003). A prior negative endoscopy was associated with 94.0% higher likelihood of diagnosing curable-stage NCGC (p=0.003). No other factors analyzed were associated with curablestage NCGC at diagnosis. Conclusions: Endoscopic screening and surveillance in select high-risk populations might increase diagnoses of curable-stage NCGC. These findings warrant confirmation in larger, prospective studies.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.13 no.2
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• pp.78-87
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• 2009

Background and Objective: We previously developed questionnaire of subhealth status. Developed questionnaire was verified about reliability and validity, but there had a lack of concurrent validity study. On this study, we will verify concurrent Validity of the Korean Version of the Subhealth Questionnaire. Methods: Guibi-tang questionnaire, chalder questionnaire and subhealth questionnaire were applied to 113 college students. After then do correlation analysis, we calculate concurrent validity of that. Results and Conclusions: As a result, subhealth questionnaire between chalder questionnaire, and subhealth questionnaire between Guibi-tang questionnaire had a significant correlation respectively. The result of this study indicate that the developed questionnaire of subhealth status was verified about concurrent validity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.1
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• pp.158-164
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• 2010

The aim of this study is to examine the reliability of Inyoung-Chongu pulse diagnosis by analyzing Inyoung-Chongu pulse measured on normal people. I measure the size of Inyoung & Chongu pulse, ratio of Inyoung to Chongu, and ratio of Chongu to Inyoung on 50 normal people. Inyoung pulse of normal people is $6.44{\pm}1.62$ volt and Chongu pulse of normal people is $6.81{\pm}1.70$ volt. The ratio of Inyoun to Chongu is $1.03{\pm}0.50$ and that of Chongu to Inyoung is $1.12{\pm}0.41$. Through this experiment, I conclude that the Inyoung-Chongu pulse diagnosis is reproducible on normal people and can develop pulse diagnosis device through comparison between Inyoung and Chongu pulse.

• Journal of Biomedical Engineering Research
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• v.30 no.1
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• pp.41-48
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• 2009

In this paper, we present the diagnosis system for swallowing disorder. There are some types of diagnosis device for swallowing disorder, for example, the video fluoroscopy, the nuclear medicine inspection, the endoscopy, EMG and motion analysis. But these systems need heavy devices or have dangerous nuclear exposure, so are uncomfortable for handicapped person. Our system has advantages of simplicity, accuracy and quantitative analysis. In addition to the diagnosis aspect, this system can be used to biofeedback treatment.

• Journal of Veterinary Clinics
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• v.32 no.1
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• pp.62-68
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• 2015

There is no reliable indicator available for the diagnosis of horse laminitis, although the disease is common and costly. This study was performed to develop a specific diagnostic biomarker for laminitis. We have identified 33 differentially expressed proteins in plasma of a horse suffering laminitis that is experimentally induced by an overdose of oligofructose, in comparison with normal horse plasma. Among the proteins, myosin-9 mRNA was found in RNA sequencing analysis to be expressed specifically in laminitis tissues compared to other horse tissues. It is thus suggested that expression of plasma myosin-9 may be used for the diagnosis of equine laminitis.