• Journal of Dental Anesthesia and Pain Medicine
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• 제23권2호
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• pp.101-110
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• 2023

Background: Dentists make various efforts to reduce patients' anxiety and fear associated with dental treatment. Dental sedation is an advanced method that dentists can perform to reduce patients' anxiety and fear and provide effective dental treatment. However, dental sedation is different from general dental treatment and requires separate learning, and if done incorrectly, can lead to serious complications. Therefore, sedation is performed by a limited number of dentists who have received specific training. This study aimed to investigate the proportion of dentists who practice sedation and the main sedatives they use in the context of the Republic of Korea. Methods: We used the customized health information data provided by the Korean National Health Insurance. We investigated the number of dental hospitals or clinics that claimed insurance for eight main sedatives commonly used in dental sedation from January, 2007 to September, 2019 at the Health Insurance Review and Assessment Service. We also identified the changes in the number of dental medical institutions by region and year and analyzed the number and proportion of dental medical institutions prescribing each sedative. Results: In 2007, 302 dental hospitals prescribed sedatives, and the number increased to 613 in 2019. In 2007, approximately 2.18% of the total 13,796 dental institutions prescribed sedatives, increasing to 3.31% in 2019. In 2007, 168 institutions (55.6%) prescribed N₂O alone, and in 2019, 510 institutions (83.1%) made claims for it. In 2007, 76 (25.1%) hospitals made claims for chloral hydrate, but the number gradually decreased, with only 29 hospitals (4.7%) prescribing it in 2019. Hospitals that prescribed a combination of N₂O, chloral hydrate, and hydroxyzine increased from 27 (8.9%) in 2007 to 51 (9%) in 2017 but decreased to 38 (6.1%) in 2019. The use of a combination of N₂O and midazolam increased from 20 hospitals (6.6%) in 2007 to 51 hospitals (8.3%) in 2019. Conclusion: While there is a critical limitation to the investigation of dental hospitals performing sedation using insurance claims data, namely exclusion of dental clinics providing non-insured treatments, we found that in 2019, approximately 3.31% of the dental clinics were practicing sedation and that N₂O was the most commonly prescribed sedative.

• 한국응용과학기술학회지
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• 제39권6호
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• pp.812-823
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• 2022

본 연구의 목적은 간호대학생의 의료 관련 감염 예방 지식과 감염관리 자신감, 표준주의 실행도 간의 관계를 확인하고 표준주의 실행도에 미치는 영향을 파악하기 위한 서술적 연구이다. 자료 수집은 2018년 10월4일부터 10월 12일까지 G 광역시에 소재한 간호대학생 160명을 대상으로 진행되었다. 연구결과 표준주의 실행도는 감염예방 지식(r=.27, p<.001), 감염관리 자신감(r=.52, p<.001)과 정의 상관관계가 있는 것으로 나타났고, 감염예방 지식은 감염관리 자신감((r=.27, p=012)과 유의한 상관관계가 있는 것으로 나타났다. 간호대학생의 표준주의 실행도에 영향을 미치는 요인은 감염관리 자신감(𝛽=0.45, p<.001), 피부 접촉 경험이 없는 경우(𝛽=0.18, p<.004), 감염예방 교육을 받은 경우(𝛽=-2.65, p<.009), 감염예방 지식(𝛽=0.15, p<.019) 순으로 나타났으며 모형의 설명력은 35%로 나타났다. 본 연구 결과를 토대로 간호대학생의 표준주의 실행도를 높이기 위하여 감염예방 지식과 감염관리 자신감을 높일 수 있는 표준주의 프로그램을 개발하여 시행하는 것이 필요하다.

• Korean Journal of Radiology
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• 제22권7호
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• pp.1044-1053
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• 2021

Objective: Motion-corrected averaging with a single-shot technique was introduced for faster acquisition of late-gadolinium-enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging while free-breathing. We aimed to evaluate the image quality (IQ) of free-breathing motion-corrected single-shot LGE (moco-ss-LGE) in patients with hypertrophic cardiomyopathy (HCM). Materials and Methods: Between April and December 2019, 30 patients (23 men; median age, 48.5; interquartile range [IQR], 36.5-61.3) with HCM were prospectively enrolled. Breath-held single-shot LGE (bh-ss-LGE) and free-breathing moco-ss-LGE images were acquired in random order on a 3T MR system. Semi-quantitative IQ scores, contrast-to-noise ratios (CNRs), and quantitative size of myocardial scar were assessed on pairs of bh-ss-LGE and moco-ss-LGE. The mean ± standard deviation of the parameters was obtained. The results were compared using the Wilcoxon signed-rank test. Results: The moco-ss-LGE images had better IQ scores than the bh-ss-LGE images (4.55 ± 0.55 vs. 3.68 ± 0.45, p < 0.001). The CNR of the scar to the remote myocardium (34.46 ± 11.85 vs. 26.13 ± 10.04, p < 0.001), scar to left ventricle (LV) cavity (13.09 ± 7.95 vs. 9.84 ± 6.65, p = 0.030), and LV cavity to remote myocardium (33.12 ± 15.53 vs. 22.69 ± 11.27, p < 0.001) were consistently greater for moco-ss-LGE images than for bh-ss-LGE images. Measurements of scar size did not differ significantly between LGE pairs using the following three different quantification methods: 1) full width at half-maximum method; 23.84 ± 12.88% vs. 24.05 ± 12.81% (p = 0.820), 2) 6-standard deviation method, 15.14 ± 10.78% vs. 15.99 ± 10.99% (p = 0.186), and 3) 3-standard deviation method; 36.51 ± 17.60% vs. 37.50 ± 17.90% (p = 0.785). Conclusion: Motion-corrected averaging may allow for superior IQ and CNRs with free-breathing in single-shot LGE imaging, with a herald of free-breathing moco-ss-LGE as the scar imaging technique of choice for clinical practice.

• Journal of Welding and Joining
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• 제32권4호
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• pp.39-45
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• 2014

Today, the development of digitized information media and info-communications are bringing many changes. Due to the development of IT thechnology, we can learn wherever, whenever, regardless of time and place. Machine drawing subject is a very important in mechanical engineering course, but it's studyed only basic theory in a short period, average 1~2weeks. So that, students think that the mechanical drawing is of minor importance. Such ideas make them difficult to impove sense of space in isometric drawing and drawing skill. Therefore, in this paper, augmented reality-based contents through the system, Mechanical Drawing of education to meet the effectiveness and satisfaction, student learning can be spontaneously it was construct self-system. And, Theoretical part of the Mechanical Drawing is proposed ensure more efficient and easier training. In this paper, we were test operation for user effectualness of proposed service at Korea Polytechnics Colleges a industrial facilities management in Daegu. Target user are 66 students, and The students were divided into experimental group and comparison group. Experimental results, experimental group was able to do systematically experience many Projection Drawing and Pictorial Drawing in short schooltime. And, The test operation results showed that have the possibility to meet education effectiveness and user satisfaction in this augmented reality-based contents system.

• 치위생과학회지
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• 제15권5호
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• pp.636-641
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• 2015

본 연구의 목적은 승무원의 구강건강과 심미적 관심도에 관한 연구로 A항공사에서 근무하는 승무원 314명을 대상으로 2014년 6~7월 동안 자기기입식 설문으로 조사되었다. 사용한 도구는 건강과 구강건강 인식, 구강건강관리, 외적이미지, 외적이미지가 직장생활에 미치는 영향이다. 수집된 자료는 PASW Statistics 18.0을 이용 하여 분석하였다. 연구결과 연령별, 경력별 구강건강 인식에 유의한 차이가 있었고, 교육수준별 삶의 질 인식에 유의한 차이가 있었다. 외적이미지가 직장생활에 미치는 영향은 연령별 유의한 차이가 있었으며, 외모관리 연간 지출비는 성별, 경력별, 소득 집단에서 유의한 차이가 있었다. 승무원은 구강건강이 전신건강보다 건강하지 않다고 인식하고 있어, 외적이미지에 구강건강이 주요한 영향요인이며, 심미증진을 위한 주기적 예방처치 및 심미처치를 시행하고 있었다. 그러나 직무 특성상 구강관리 자가평가가 낮게 조사되어 구강관리 행위 실천을 위한 방안모색이 요구된다. 또한 구강관리가 전신건강을 유지하는데 필수적인 만큼 이에 대한 관심 증대가 요구된다.

• 대한약침학회지
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• 제11권3호
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• pp.17-31
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• 2008

Objective: To review the theoretic basis of the Sa-Ahm 5 Element acupuncture devised about 360 years ago, papers and books were researched. Methods: Total of 59 books and papers ranging from ancient Huang Di nei jing to modern Bio Medical Acupuncture for Pain Management were researched to study the basic theory of it in relation to the 5 Shu points, Results: Gao-mu in Chinese Ming dynasty, for the 1st time, had used 5 Shu points based on creation cycle as tonification and sedation treatment respectively and named it as 'tonification and sedation treatment of self meridian' but since then, this method, without special reasons, has been rarely used until Sa-Ahm's new doctrine that include the concept of destruction cycle was asserted. Conclusions: Sa-Ahm 5 Element acupuncture is a method which uses 5 Shu points from the viewpoints of simultaneous tonification and sedation methods which are based on promotion and control cycles. Though it is nowadays mostly-used method in accordance with practitioner's points, it needs to be set guidelines by which to effectively practice Sa-Ahm acupuncture.

• BMB Reports
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• 제36권1호
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• pp.78-81
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• 2003

The prevention of cancer is one of the most important public health and medical practices of the $21^{st}$ century. We have made much progress in this new emerging field, but so much remains to be accomplished before widespread use and practice become common place. Cancer chemoprevention encompasses the concepts of inhibition, reversal, and retardation of the cancer process. This process, called carcinogenesis, requires 20-40 years to reach the endpoint called invasive cancer. It typically follows multiple, diverse and complex pathways in a stochastic process of clonal evolution. These pathways appear amenable to inhibition, reversal or retardation at various points. We must therefore identify key pathways in the evolution of the cancer cell that can be exploited to prevent this carcinogenesis process. Basic research is identifying many genetic lesions and epigenetic processes associated with the progression of precancer to invasive disease. Many of these early precancerous lesions favor cell division over quiescence and protect cells against apoptosis when signals are present. Many oncogenes are active during early development and are reactivated in adulthood by aberrant gene promoting errors. Normal regulatory genes are mutated, making them insensitive to normal regulatory signals. Tumor suppressor genes are deleted or mutated rendering them inactive. Thus there is a wide range of defects in cellular machinery which can lead to evolution of the cancer phenotype. Mistakes may not have to appear in a certain order for cells to progress along the cancer pathway. To conquer this diverse disease, we must attack multiple key pathways at once for a predetermined period of time. Thus, agent combination prevention strategies are essential to decrease cancer morbidity. Furthermore, each cancer type may require custom combination of prevention strategies to be successful.

• Biomolecules & Therapeutics
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• 제13권2호
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• pp.65-77
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• 2005

Present article reviews about clinical pharmacology of mycophenolic acid (MPA), the active form of mycophenolate mofetil (MMF), as widely used component of immunosuppressive regimens in the organ transplantation field. MMF, used alone or concomitantly with cyclosporine or tacrolimus, has approved in reducing the incidence of acute rejection and has gained widespread use in solid organ such as kidney, heart and liver transplantation. The application of MPA and development of MMF has shown a considerable impact on immunosuppressive therapy for organ transplantation as a new immunosuppressive agent with different mechanism of action from other drugs after early 1990s. In particular aspect, use of MMF, a morpholinoethyl ester of MPA, represented a significant advance in the prevention of organ allograft rejection as well as allograft and patient survival. In considering MMF clinical data, it is important to note that there is a strong correlation between high MPA area under curve(AUC) values and a low probability of acute allograft rejection. Individual trials have shown that MMF is generally well tolerated and revealed that MMF decreased the relative risk of developing chronic allograft rejection compared with azathioprine. Recent clinical investigations suggested that improved effectiveness and tolerability will results from the incorporation of MPA therapeutic drug monitoring into routine clinical practice, providing effective MMF dose individualization in renal and heart transplant patients. Therefore, MMF has a selective immunosuppressive effect with minimal toxicity and has shown to be more effective that other agents as next step of immunosuppressive agents and regimens that deliver effective graft protection and immunosuppression along with a more favorable side effect.

• Journal of Preventive Medicine and Public Health
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• 제41권2호
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• pp.100-106
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• 2008

Objectives : We measured behavioral factors associated with Koreans receiving gastric cancer screening based on a socio-ecological model, in part to develop strategies to improve cancer screening rates. Methods : A telephone survey was conducted with 2,576 people chosen through stratified random sampling from April 1 - May 31, 2004. Collected information included gastric cancer screening, socio-demographic factors, and socio-ecological factors at intrapersonal, interpersonal, community, and public policy levels. Results : Among 985 survey respondents(380 men and 605 women), 402 had received gastric cancer screening. Logistic analysis was performed to compare those screened and unscreened. 'Age' was the only demographic factor that showed a statistically significant association with getting screening. People in their fifties (OR=1.731, 95% CI=1.190-2.520) and sixties (OR=2.098, 95% CI=1.301-3.385) showed a higher likelihood of getting screened, compared to those in the forties. 'Accessibility to a medical institution' was a significant factor related to having gastric cancer screening at the intrapersonal level. At the interpersonal level, recommendations by family members to be screened and a family practice of routine cancer screening were significantly related. People with frequent education about cancer screening or with stronger social feelings that cancer screening is necessary also demonstrated significantly higher tendencies to be screened. Conclusions : In conclusion, a socio-ecological model seems appropriate for explaining gastric cancer screening behavior and associated factors. Health planners should develop integrated strategies to improve cancer screening rates based on socio-ecological factors, especially at the interpersonal and community levels.

• 한국환경보건학회지
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• 제36권6호
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• pp.472-479
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• 2010

The purpose of this study was to investigate the concentration of indoor air pollutants at 63 elementary schools, 41 middle schools and 51 high schools in Ulsan from the beginning of May to the end of December, 2008. To assess the indoor air quality of the various classrooms, the 8 indoor air pollutants such as $CO_2$, CO, $NO_2$, $O_3$, $PM_{10}$, TVOCs, HCHO and TBC were measured and analyzed. The mean concentrations of $PM_{10}$ and TBC in the elementary schools were significantly higher than those of middle and high schools (p < 0.01). For the HCHO, the multi-use practice rooms showed an average 1.5 times higher than general classrooms. In schools located in urban areas, the concentrations of CO, $O_3$, $PM_{10}$, HCHO and TBC were lower than in the vicinity of industrial complexes. The exceeding rate of the school air quality maintenance limits in the 6 air pollutants by law were 6.7%, 3.5%, 1.7%, 18.2%, 13.0% and 18.4% for $CO_2$, $NO_2$, $O_3$, $PM_{10}$, HCHO and TBC, respectively. Based on these results $PM_{10}$ and TBC have to be in the order of priority of need to improve the classroom air quality in elementary school of Ulsan.