• Title/Summary/Keyword: Korea Environment Institute

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Acute and Sub-chronic Oral Toxicity Study of Ammonium Persulfate in Spraque-Dawley Rats

  • Kim, Yong-Soon;Baek, Min-Won;Sung, Jae-Hyuck;Ryu, Hyun-Youl;Kim, Jin-Sik;Cho, Hyun-Sun;Choi, Byung-Gil;Song, Min-Sub;Song, Moon-Yong;Baik, Eun-Ju;Choi, Young-Kuk;Kim, Jong-Kyu;Yu, Il-Je;Song, Kyung-Seuk
    • Toxicological Research
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    • v.25 no.3
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    • pp.132-139
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    • 2009
  • The toxicity test of ammonium persulfate was conducted to ensure of its potential toxic effects according to the single-dose acute oral toxicity study (OECD Guideline 423) and 90-day repeated dose sub-chronic oral toxicity study guideline (OECD Guideline 408) for establishing national chemical management system, and matching in the Globally Harmonized Classification System (GHS) category. In acute oral toxicity study, pasty stool, perineal contamination and temporary body weight decrease were observed after dosing 1st and 2nd challenge (300 mg/kg body weight). All test animals were dead within 6 hours after dosing at 3rd challenge (2000 mg/kg body weight). Therefore, the GHS class of test substance is considered class 4. In sub-chronic toxicity study, body weight changes, food consumptions, hematological, biochemical and pathological examination did not show any noticeable and significant differences between the administered (5, 20, 80 mg/kg body weight) and control (vehicle only) group animals. Based on these results, the no observed adverse effect level (NOAEL) is considered above 80 mg/kg body weight.

An analysis of indoor environment research trends in Korea using topic modeling : Case study on abstracts from the journal of the Korean society for indoor environment (토픽모델링을 활용한 실내환경 분야 연구동향 파악 : 실내환경학회지 초록 사례연구)

  • Jeon, Hyung Jin;Kim, Do Youn;Han, Kook Jin;Kim, Dong Woo;Son, Seung Woo;Lee, Cheol Min
    • Journal of odor and indoor environment
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    • v.17 no.4
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    • pp.322-329
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    • 2018
  • The objective of this study is to identify the research trend in the field of indoor environment in Korea. We collected 419 papers published in the Journal of the Korean Society for indoor environment between 2004 and 2018, and attempted to produce datasets using a topic modeling technique, Latent Dirichlet Allocation(LDA). The result of topic modeling showed that 8 topics ("VOCs investigation", "Subway environment", "Building thermal environment", "School health", "Building particulate matter", "Asbestos risk", "Radon risk", "Air cleaner and treatment") could be extracted using Gibbs sampling method. In terms of topic trends, investigation of volatile organic compounds, subway environment, school health, and building particulate matter showed a decreasing tendency, while the building thermal environment, asbestos risk, radon risk, air cleaners, and air treatment showed an increasing tendency. The results of this topic modeling could help us to understand current trends related indoor environment, and provide valuable information in developing future research and policy frameworks.

A Study on Definition of Subsurface Environment in Korea (지중 환경의 정의에 대한 정책적 고찰)

  • Yang, Jihoon;Yoo, Keunje;Hwang, Sang Il
    • Journal of Soil and Groundwater Environment
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    • v.21 no.1
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    • pp.14-21
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    • 2016
  • Many improper development action were performed at subsurface environment, because there were not any definition about subsurface environment in Korea. The purpose of this study was to establich a definition on subsurface environment. Subsurface environment could be divided by subsurface natural environment and subsurface living environment. The soil, groundwater, ecosystems, landscapes, underground space (naturally occurred) were included in subsurface natural environment. And space and facilities used by human were classified as subsurface living environment.