• 대한치과보철학회:학술대회논문집
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• 1999.04a
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• pp.91.1-91.1
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• 1999

• Journal of Ginseng Research
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• v.45 no.2
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• pp.325-333
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• 2021

Background: Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders. Enhancing hippocampal neurogenesis by promoting proliferation and differentiation of neural stem cells (NSCs) is a promising therapeutic strategy for AD. 20(S)-protopanaxadiol (PPD) and oleanolic acid (OA) are small, bioactive compounds found in ginseng that can promote NSC proliferation and neural differentiation in vitro. However, it is currently unknown whether PPD or OA can attenuate cognitive deficits by enhancing hippocampal neurogenesis in vivo in a transgenic APP/PS1 AD mouse model. Here, we administered PPD or OA to APP/PS1 mice and monitored the effects on cognition and hippocampal neurogenesis. Methods: We used the Morris water maze, Y maze, and open field tests to compare the cognitive capacities of treated and untreated APP/PS1 mice. We investigated hippocampal neurogenesis using Nissl staining and BrdU/NeuN double labeling. NSC proliferation was quantified by Sox2 labeling of the hippocampal dentate gyrus. We used western blotting to determine the effects of PPD and OA on Wnt/GSK3β/β-catenin pathway activation in the hippocampus. Results: Both PPD and OA significantly ameliorated the cognitive impairments observed in untreated APP/PS1 mice. Furthermore, PPD and OA significantly promoted hippocampal neurogenesis and NSC proliferation. At the mechanistic level, PPD and OA treatments resulted in Wnt/GSK-3β/β-catenin pathway activation in the hippocampus. Conclusion: PPD and OA ameliorate cognitive deficits in APP/PS1 mice by enhancing hippocampal neurogenesis, achieved by stimulating the Wnt/GSK-3β/β-catenin pathway. As such, PPD and OA are promising novel therapeutic agents for the treatment of AD and other neurodegenerative diseases.

• Journal of Fashion Business
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• v.16 no.5
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• pp.106-113
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• 2012

This study intend to research color preferences about innerwear(specially brassiere) and draw a comparison of color preference's differences among the Korea, China and Hong Kong. The subjects of study are female students of universities in Korea, China and Hong Kong. The data analysis was done with the statistical treatment in SPSS 14.0, and the results are as follows. Female students of universities in Korea, China and Hong Kong are distinguished from wearing color and preference color of innerwear. Korea and China female students prefer skin color to the other color but most of Hong Kong female students prefer black color. In case of red color, Korea female students don't select a red color as a preference color but even if some students select a red color, China and Hong Kong females prefer a red color. The traditional color opinions of Korea, China and Hong Kong are the same as a Yin-Yang School. But these days they have different color opinions because of cultural, political and ideological elements. Korea females like skin and white colors because these colors don't appear on the outwear surface. Korean have an inclination toward conservatism and use the color according to ideological and deceptive orders of the Confucianism. Hong Kong have a different color preference from China because they have chances of receiving the other cultures for example United Kingdom, Japan and so on.

• The Journal of Asian Finance, Economics and Business
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• v.6 no.4
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• pp.9-17
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• 2019

The purpose of this research is to review historical development of Islamic finance in individual East Asian economies, including China, Japan, South Korea and Hong Kong, and examine the success factors of the Hong Kong Sukuk issuances in 2014-2017. The research is a qualitative study applying case study method. It is found that the East Asian economies do play efforts to develop their Islamic capital markets although they have very limited size of Muslim population. Their progress on this development generally remains to be slow. The Hong Kong Sukuk is a breakthrough, carrying a total issuance value of US$3 billion. The Sukuk issuances, treated as a kind of asset-backed securities with restrictions on financing purposes, are distributed to international investors by investment banks from Hong Kong, Middle East and Malaysia. Success factors of these issuances include involvement of an issuer with high credit quality, recognition by central bank for using the Sukuk in its discount facility for commercial banks, centralized clearing services for the Sukuk and global banking network for underwriting the Sukuk. The lessons from the Hong Kong Sukuk are good references for other economies to develop their regional Islamic capital markets and to integrate the markets into the global capital market.

• Korea Trade Review
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• v.47 no.2
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• pp.31-46
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• 2022

The purpose of this study is to measure the degree of discrepancies in the bilateral trade data between South Korea and its five major trade partners and to identify the key factors causing the discrepancies. By analyzing statistics based on the CIF/FOB ratio estimation and taking into consideration the trade flow via Hong Kong, the study finds that the discrepancies in South Korea's trade data with the US, Vietnam, and Japan are insignificant. In case of Hong Kong, however, the value of South Korea's import from Hong Kong is extensively inconsistent with Hong Kong's export to South Korea(i.e. the mirror data) while the value of South Korea's export to Hong Kong generally corresponds to its mirror data. Such discrepancies are caused by differences in recording re-exports, which are often found in the trade flow via entrepôt economics including Hong Kong. Meanwhile, discrepancies in reported bilateral trade flows between South Korea and People's Republic of China(PRC) remain relatively marginal. The discrepancy of statistics between South Korea as the exporter and PRC as the importer is mainly caused by the trade flow via Hong Kong. On the other hand, the discrepancy of statistics between South Korea as the importer and PRC as the exporter is assumably due to the differences in attribution of trade partners.

• Journal of Nutrition and Health
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• v.15 no.4
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• pp.242-248
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• 1982

Samples of six varieties of soybeans (Bongeui, Danyup-kong, Dongpuktae, Hwangkeum-kong, Jangyup-kong, Kanglim) were analysed for their chemical composition and amino acid content by A.O. A. C. method (1980) and amino acid analyser in order to determine their nutritive value. 1) Chemical composition of soybean was affected by the varieties. The protein contents of 6 varieties of soybeans grown at Suwon were 48.84% in Kanglim, 45.57% in Bongeui, 43.73% in Dongputtae, 41.56% in Jangyup-kong, 40.86% in Hwangkeum-kong, and 40.05% in Danyup-kong. 2) Compared to FAO (1970) chemical score of soybean (A/E ratio and A/T ratio), three varieties of Korean soybeans (Bongeui, Danyup-kong, Hwangkeum-kong) showed higher levels of nutritive value in protein and three varieties of soybeans (Dongpuktae, Jangyup-kong, Kanglim) showed lower levels of nutritive value in protein. From protein content and chemical score, Bongeui showed the greatest potential for the best high protein source among Korean soybean varieties. 3) The determination of first limiting amino acid in six varieties of Korean soybeans by whole egg protein was methionine, but valine was the first limiting amino acid in Danyup-kong and methionine- cystine was other five varieties of Korean soybeans by FAO provisional amino acid pattern.

• Safety and Health at Work
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• v.6 no.3
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• pp.192-199
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• 2015

Background: Overweight, obesity, and cardiovascular disease risk factors are prevalent among firefighters in some developed countries. It is unclear whether physical activity and cardiopulmonary fitness reduce cardiovascular disease risk and the cardiovascular workload at work in firefighters. The present study investigated the relationship between leisure-time physical activity, cardiopulmonary fitness, cardiovascular disease risk factors, and cardiovascular workload at work in firefighters in Hong Kong. Methods: Male firefighters (n = 387) were randomly selected from serving firefighters in Hong Kong (n = 5,370) for the assessment of cardiovascular disease risk factors (obesity, hypertension, diabetes mellitus, dyslipidemia, smoking, known cardiovascular diseases). One-third (Target Group) were randomly selected for the assessment of off-duty leisure-time physical activity using the short version of the International Physical Activity Questionnaire. Maximal oxygen uptake was assessed, as well as cardiovascular workload using heart rate monitoring for each firefighter for four "normal" 24-hour working shifts and during real-situation simulated scenarios. Results: Overall, 33.9% of the firefighters had at least two cardiovascular disease risk factors. In the Target Group, firefighters who had higher leisure-time physical activity had a lower resting heart rate and a lower average working heart rate, and spent a smaller proportion of time working at a moderate-intensity cardiovascular workload. Firefighters who had moderate aerobic fitness and high leisure-time physical activity had a lower peak working heart rate during the mountain rescue scenario compared with firefighters who had low leisure-time physical activities. Conclusion: Leisure-time physical activity conferred significant benefits during job tasks of moderate cardiovascular workload in firefighters in Hong Kong.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7713-7720
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• 2015

Background: Colorectal cancer (CRC) is one of the most common cancers. This study aimed to compare the uptake of CRC testing in the general public and in ethnic minorities in Hong Kong. Materials and Methods: This cross-sectional survey covered 2,327 South Asian and Chinese adults aged over 50, recruited from two separate studies. A structured questionnaires were administered by research staff over the telephone or in faceto-face interviews. Results: The uptake rate of CRC testing among South Asians was significantly lower than that of the general population in Hong Kong. Factors associated with the uptake rate were health professional's recommendation, perception of regular visits to doctor, use of complementary therapy, ethnicity, perceived susceptibility to cancer, presence of chronic illness, and education level. In addition, a significant interaction (p<0.05) between ethnicity and health professionals' recommendations was found, after adjustment for the main independent factors identified. Conclusions: Older people with lower educational attainment, without chronic illness and those have lower perceived susceptibility to cancer may be targeted for CRC testing promotion in the society. In addition, health professionals can play a highly influential role in promoting such testing, particularly among ethnic minorities.

• Korean Journal of Agricultural Science
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• v.16 no.2
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• pp.138-151
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• 1989

In order to find the effects of seed size on the early seedling growth and yield of soybean, three soybean cultivars in Korea were investigated. Seed size was classified into large and small according to the weight and planted in pots(1/5000a) and in the field. Three soybean cultivars respresenting large, medium and small grains were Hwangkeum-kong, Kwangkyo and Bangsa-kong respectively. These cultivars were planted on June 20, 1987. 1. The plant height, stem diameter, root length and leaf area index(LAI) of the seed with large size seemed larger than the seed with small size regardless of cultivars. 2. The fresh and dry weight were different depending upon the grain sizes. The large grain had heavier fresh and dry weight than the small grains. 3. The protein consumption rate of the cotyledon of Bangsa-kong with small grain size was faster than the Hwangkeum-kong with large grain size. 4. The stem length, stem diameter and number of main stem node of the seed with large size seemed larger than the seed with small size. Large grains of Hwangkeum-kong were the highest in the number of branch node and number of node. 5. The number of pods and grains per plant of Bangsa-kong with small grain size was larger than the Kwangkyo with large grain size. 6. The yield per 10a for Hwangkeum-kong, Hwangkyo and Bangsa-kong were 226.3kg, 193.0kg and 192.8kg, respectively and they were all statistically different. The yield increases of large grains over small grains in the Hwangkeum-kong, Kwangkyo, and Bangsa-kong were 7.4%, 8.0% and 9.2%, respectively.

• Journal of Nutrition and Health
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• v.38 no.7
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• pp.512-520
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• 2005

Phytoestrogens, especially Yak-kong or soybean-derived isoflavones have been traditionally used as a supplement of estrogen for preventing postmenopausal osteoporosis in oriental folk medicine. In a previous study, we demonstrated that as Yak-kong and soybean increased MG-63 human osteoblastic cell proliferation, the expression of estrogen receptor $\alpha\;and\;beta\;(ER\;\alpha:\;ER\;\beta$) both were increased. However, the increased level of ER $\alpha$ is much higher than that of ER$\beta$. To determine whether the altered level of ER $\alpha$ expression affects Yak-kong or soybean induced MG-63 cell proliferation, we established cell lines stably expressing either ER $\alpha$ or antisense ER $\alpha$ RNAs. Increased expression of ER a in MG- 63 cells (ER $\alpha$-MG63) enhanced Yak-kong or soybean induced proliferation which paralleled with the enhanced expression of IGF-I. Inhibition of ER $\alpha$ expression by antisense $ER\;\alpha\;RNAs\;(As-ER\;\alpha-MG63$) caused these cells to insensitize Yak- kong or soybean induced proliferation and IGF-I expression. Furthermore, the comparable effects between Yak-kong and the combined treatment of genistein and daidzein at $0.5\;{\times}\;10^{-8}M$, which is a concentration of these two isoflavones similar to Yak-kong at 0.001 mg/ml, on cell proliferation and IGF-I expression in $ER\;\alpha-MG63\;or\;As-ER\;\alpha-MG63$ cells demonstrate that ER $\alpha$ plays an important, active role in MG-63 cell proliferation induced by phytoestrogens, especially Yak-kong or soybean derived isoflavones.