• Title/Summary/Keyword: Kojinyumja

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Effect of Kojinyumia(固眞飮子) on Galactosamie Induced hepatoxicity on Rats (고진음자(固眞飮子)가 galactosamine으로 유발한 흰쥐의 간중독에 미치는 영향)

  • Won, Chul-Hwan;Jung, Sung-Hyun;Lim, Seong-Woo;Shin, Gil-Cho;Yoon, Sang-Hyup;Lee, Won-Chol
    • The Journal of Dong Guk Oriental Medicine
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    • v.6 no.1
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    • pp.137-149
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    • 1997
  • The purpose of this study is to observe the protective effect of Kojinyumja on serum reaction and hepatic tissue in galactosamine treated rats. In this study, the experimental rats divided four group(Normal group, Control group, Sample A group, and Sample B group) : Under the same condition, normal and control group were administered water, sample A, B group were administered Kojinyumja for 8days. And then, both control group and Sample B group were injected to abdomen with galactosamine for 1day. The rates of of glutathione, lipid peroxide, GOT, GPT, ${\gamma}$-GTP, ALP, LDH, and contents of bile acid level were measured. The results are as follows : The glutathione rate significantly increased in sample group, the others (lipid peroxide, GOT, GPT, ${\gamma}$-GTP, ALP, LDH, bile acid) significantly decreased in sample group.

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