• The Korean Journal of Nuclear Medicine
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• v.30 no.4
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• pp.493-501
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• 1996

To assess contribution of T1-201 rest-24 hour delay redistribution in detection of viable myocardium, we studied the predictive value of this redistribution in 17 patients who peformed rest-24 hour delay perfusion SPECT before bypass surgery. Regional wall motion was compared with gated SPECT in 10 patients and echocardiography in 7 patients before and after bypass surgery. Rest and 24 hour delayed uptakes were scored from 0 (normal perfusion) to 3 (defect). In rest SPECT, 56 segments showed perfusion decrease. Thirty four segments(61%) improved after surgery and were defined as viable Nineteen(34%) segments had more uptake of T1-201 at 24 hour delay, and the other 37 segments did not. In 81%(25/31) of segments with mildly decreased perfusion, wall motion after bypass surgery improved, 57% (8/14) of segments with severely decreased perfusion improved, and 9%(1/11) of segments with defects improved. In 14 among 19 segments which had more T1-201 uptakes at 24 hour delay, wall motion was improved(positive predictive value of redistribution: 74%). 20 among 37 segments which had persistent decreases in rest-24 hour redistribution improved and 17 did not(negative predictive value: 46%). Segments having severe perfusion decrease or defects showed improved wall motion after surgery in 64%(7/11), if it had redistribution at delay. Segments with either mildly decreased uptake in resting or rest-delayed redistribution showed improved wall motion in 76%(32/42). Among the 14 segments which showed improvement in wall motion, 10 had partial reversibility in stress-rest images and the other 4 had persistent perfusion defects in stress-rest images. These 4 segments were found viable only with rest-24 hour delayed perfusion SPECT. We concluded that rest T1-201 uptake or redistribution at 24 hour delay should be referred as an evidence to warrant postoperative improvement of abnormal wall motion and we could predict myocardial viability with preoperative rest-24 hour delay perfusion SPECT in the segments with rest perfusion decreases.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.5 no.2
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• pp.119-130
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• 2000

Mn, Zn, Cd and Pb in shells of Littorina brevicula, which lives ubiquitously in intertidal zone around the Korean coast, were analyzed to determine the relationship between metal levels in its shell, ambient seawater and its tissue. Periwinkles and seawater samples were collected from 38 sites along the Korean coast in January 1997. Mn contents in shells of this organism show the range of 7.0 ${\mu}g$/g-211 ${\mu}g$/g (mean 59 ${\mu}g$/g) and are the lowest in northern east coast but high in western south and west coast. Close relationship between Mn contents in shells and metal levels both in seawater and in tissues indicates that Mn in shell might be incorporated from ambient seawater by a biological process. Although the contents of Cd in shells did not reflect the distribution of total Cd in seawaters and they were very low compared to those in tissues, they followed spatial gradient of contents in tissues. However, the spatial distribution of Zn contents in shells accords neither ambient seawater nor tissues, while it is negatively correlated with the contents of Na in shells. This fact suggests that Zn contents might be controlled by salinity of ambient seawater. On the contrary, Zn contents in highly polluted sites near Onsan Bay show generally higher levels than other sites. The contents of Pb show the range of 0.1 ${\mu}g$/g-17.5 ${\mu}g$/g (mean 1.01 ${\mu}g$/g) and the highest in sites near Onsan Bay. Although the spatial distribution of shell Pb does not follow those of tissue, Pb in shells of Littorina brevicula may be controlled both by shell secretion process and by Pb levels in ambient seawater because the contents of Pb in the shell decrease steadily with growth and vary with levels of Pb in ambient seawater.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.2 no.1
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• pp.21-30
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• 1997

The present study reports the density, growth and production of a razor clam, Sinollovacula constricta, which is known to be one of the important fishreies catches from the Korean tidal flat. The annual yield reached to about 6,000 metric tons per year till 1994. The study was conducted on the Hwaseong tidal flat located on the central west coast, 40 kilometers south-west from Seoul. The annual yield of the razor clam in this area reached to about 50% of the total catch from the whole Korean coast. Samples were colleted monthly at 14 occasions from May 1992 to August 1993. Density of S. constricta ranged from 92~165 individuals per square meter during the study period. General trend of decreasing density was observed when the animal became older, but an exception was the year class of 1991 whose density was lower than that of 1990. The size of the shell was clearly separated into two classes during fall and winter (from September to February), however, the maximum frequency of the length of small size classes moved to right after February. It indicates a fast growth of young clams from spring to summer. Fast growth of the shell could also be examined by the growth curve. The shell growth of the whole life span was described by the von Bertalanffy equation of $L_t=89.3{\times}[1{\exp}\{-0.58{\times}(t+0.73\}]$. The growth in flesh dry weight was well fitted to the Gompertz growth model with the equation, $W_t=5.00{\times}{\exp}\{-4.31{\times}{\exp}(-0.043{\times}t)\}$. The clam lost about 30% of the body weight during spawning in August. The annual production calculated based on the data from September 1992 to August 1993 amounted to 150 g $DW{\cdot}m^{-2}{\cdot}yr^{-1}$ which was 2~50 fold higher than those of other bivalves occurred in Korea. This estimate was patitioned by each year classes; 87.5 by 1992, 53.4 by 1991, 59.0 by 1990 and -30.0 g $DW{\cdot}m^{-2}{\cdot}yr^{-1}$ by 1989 year class.

• Journal of Biosystems Engineering
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• v.8 no.1
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• pp.47-60
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• 1983

상온통풍(常溫通風)을 이용(利用)한 In-bin drying에 대(對)한 많은 실험결과(實驗結果)에 의(依)하면 우리나라 10월(月)의 기상조건(氣象條件)은 저온건조(低溫乾燥) system에 적합(適合)한 건조능력(乾燥能力)을 가지고 있는 것으로 나타났다. 최근(最近) Computer를 이용(利用)한 Simulation model이 개발(開發)되어 건조현상(乾操現象)에 관(關)한 경제적(經濟的)이고 효율적(效率的)인 분석(分析)이 가능(可能)하게 되었다. 이러한 분석결과(分析結果)에 의(依)하면 초기함수율(初期含水率)이 높은 벼를 Full-bin을 이용(利用)한 상온통풍건조(常溫通風乾操)를 할 경우(境遇) 건조기간(乾燥期間)이 길어지며 bin내(內)의 상층부(上層部) 곡물(穀物)이 변질(變質)되는 문제점(問題點)이 발생(發生)하였다. 또한 벼의 수확작업체계(收穫作業體系)가 관행(慣行) 및 Binder작업체계(作業體系)에서 점차(漸次) Combine작업체계(作業體系)로 전환(轉換)되어감에 따라 포장(圃場)에서의 건조(乾燥)가 어려우며 예취(刈取), 탈곡작업과정(脫穀作業過程)에서의 기계적(機械的)인 곡물(穀物) 손실(損失)을 줄이기 위(爲)하여 함수율(含水率)이 비교적(比較的) 높은 벼를 수확(收穫)하여야 한다. 본(本) 연구(硏究)의 목적(目的)은 상온통풍건조(常溫通風乾燥)에 있어서 건조능력(乾燥能力)을 증가(增加)시키기 위(爲)하여 곡물(穀物)을 일정기간(一定期間) 나누어서 bin에 넣고 건조(乾燥)를 하는 Layer drying의 Simulation model을 개발(開發)하고 이 Model에 수원지방(水原地方)의 7년간(年間) 평균(平均) 기상자료(氣象資料)를 입력(入力)시켜 곡물(穀物)의 초기함수율(初期含水率), 투입량(投入量), 투입기간(投入期間)의 변화(變化)에 따른 Layer drying현상(現象)을 규명(糾明)하는데 있다. Simulation에 사용(使用)된 bin의 크기는 직경(直徑) 2m, 깊이 1.5m이며 송풍(送風)팬의 용량(容量)은 0.5HP이었다. Simulation분석(分析) 결과(結果)를 요약(要約)하면 다음과 같다. (1) Layer drying의 Simulation model을 개발(開發)하였으며 이 Model은 벼의 상온통풍건조(常溫通風乾燥) 실험(實驗)에서 함수량(含水量) 변화(變化)의 이론치(理論値)와 실제실험치(實際實驗値)가 잘 일치(一致)하였다. (2) 곡물투입기간(穀物投入期間) 1일(日)을 Full-bin drying으로 간주(看做)할 때 Layer drying의 건조성능(乾燥性能)은 Full-bin보다 높은 것으로 나타났다. (3) 연속송풍(連續送風)(24시간(時間))을 할 경우(境遇) 곡물투입기간(穀物投入期間)이 증가(增加)함에 따라 건조기간(乾燥期間)의 감소경향(減少傾向)은 단속송풍(斷續送風)인 경우(境遇)보다 적었지만 건조기간(乾燥期間)은 단축(短縮)되었다. 그러나 건조(乾燥)에너지의 소모(消耗)는 단속송풍(斷續送風)일 때보다 크게 나타났다. (4) 단속송풍(斷續送風)(9 : 00AM~6 : 00PM)일 경우(境遇) 곡물투입기간(穀物投入期間)을 증가(增加)시키면 건조기간(乾燥期間)이 크게 줄어 들었다. (5) 곡물(穀物)의 초기함수율(初期含水率)이 21% 이하(以下)일 경우(境遇) 연속(連續) 및 단속송풍(斷續送風)에서 건조기간(乾燥期間)의 차이(差異)가 별로 없었다. (6) 곡물(穀物)의 초기함수율(初期含水率)이 높으면 Full-bin drying에서는 상부층(上部層)에 곡물(穀物)이 변질(變質)될 우려(憂慮)가 있으나 Layer drying에서는 곡물투입량(穀物投入量)을 조절(調節)하면 이것을 방지(防止)할 수 있었다. (7) 건조(乾燥)가 완료(完了)된 후(後) 층별(層別) 최종곡물(最終穀物) 함수율(含水率)은 모든 건조조건(乾燥條件)에서 동일(同一)하였으나 bin의 하부층(下部層)은 과건조(過乾燥) 물상(物象)을 일으켰다.

• Horticultural Science & Technology
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• v.32 no.3
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• pp.318-329
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• 2014

In order to gain insight into the physiological responses of plants to high temperature stress, the effects of temperature on Chinese cabbage (Brassica campestris subsp. napus var. pekinensis cv. Detong) were investigated through analyses of photosynthesis and chlorophyll fluorescence under 3 different temperatures in the temperature gradient tunnel. Growth (leaf length and number of leaves) during the rosette stage was greater at ambient $+4^{\circ}C$ and ambient $+7^{\circ}C$ temperatures than at ambient temperature. Photosynthetic $CO_2$ fixation rates of Chinese cabbage grown under the different temperatures did not differ significantly. However, dark respiration rate was significantly higher in the cabbage that developed under ambient temperature relative to elevated temperature. Furthermore, elevated growth temperature increased transpiration rate and stomatal conductance resulting in an overall decrease of water use efficiency. The chlorophyll a fluorescence transient was also considerably affected by high temperature stress; the fluorescence yield $F_J$, $F_I$, and $F_P$ decreased considerably at ambient $+4^{\circ}C$ and ambient $+7^{\circ}C$ temperatures, with induction of $F_K$ and decrease of $F_V/F_O$. The values of RC/CS, ABS/CS, TRo/CS, and ETo/CS decreased considerably, while DIo/CS increased with increased growth temperature. The symptoms of soft-rot disease were observed in the inner part of the cabbage heads after 7, 9, and/or 10 weeks of cultivation at ambient $+4^{\circ}C$ and ambient $+7^{\circ}C$ temperatures, but not in the cabbage heads growing at ambient temperature. These results show that Chinese cabbage could be negatively affected by high temperature under a future climate change scenario. Therefore, to maintain the high productivity and quality of Chinese cabbage, it may be necessary to develop new high temperature tolerant cultivars or to markedly improve cropping systems. In addition, it would be possible to use the non-invasive fluorescence parameters $F_O$, $F_V/F_M$, and $F_V/F_O$, as well as $F_K$, $M_O$, $S_M$, RC/CS, ETo/CS, $PI_{abs}$, and $SFI_{abs}$ (which were selected in this study), to quantitatively determine the physiological status of plants in response to high temperature stresses.

• Horticultural Science & Technology
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• v.35 no.1
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• pp.38-45
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• 2017

We investigated the effects of rising temperatures on the photosynthesis, mineral composition, and growth of radish (Raphanus sativus var. hortensis) in a winter cropping system using a temperature gradient tunnel to predict the impact of rising global temperatures. Vegetative growth, including shoot and root fresh and dry weights, shoot length, and root length and diameter, was high under elevated temperatures (ambient $+4^{\circ}C$ and $+7^{\circ}C$) compared with ambient temperature. At elevated temperatures, the N, P, Ca, Mg, and Fe contents were high in shoots, whereas in roots, the K, Ca, Mg, and Fe contents were high and the Cu content was low. The maximum photosynthetic rates ($22.1{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$ at ambient temperature $+4^{\circ}C$ and $22.9{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$ at ambient temperature $+7^{\circ}C$) at elevated temperatures were more than twice that ($9.7{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$) at ambient temperature, whereas the water use efficiency was lower at elevated temperatures. These results suggest that rising global temperatures will lead to increased mineral absorption and photosynthesis in radish in winter cropping systems, subsequently favoring plant growth, although the water requirements will be high.

• Journal of Environmental Impact Assessment
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• v.25 no.3
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• pp.209-221
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• 2016

The section from water source to 2.6km upper stream of Hantan River is protected as the drinking water quality protection area according to guidelines of Ministry of Environment, because water source of the Gwanin water intake plant has been known the river. However, opinions were consistently brought up that the standard of water source protection zone must be changed with using underground water as water source because of contribution possibility of underground water as the water source of Gwanin water intake facility. In this regard, hydrogeologic investigation including resistivity survey and hydrogeochemical investigation were carried out to assess water source and infiltration of contaminant for the plant. Quaternary basaltic rocks (50m thick with four layers) covered most of the study area on the granite basement. As the result of the resistivity survey, it is revealed that permeable aquifer is distributed in the boundary of two layers: the basaltic layer with low resistivity; and the granite with high resistivity. Considering of outflow from Gwanin water intake facility, the area possessing underground water was estimated at least $5.7km^2$. The underground water recharged from Cheorwon plain was presumed to outflow along the surface of unconformity plane of basalt and granite. Based on field parameters and major dissolved constituents, groundwater and river water clearly distinguished and the spring water was similar to groundwater from the basaltic aquifer. Temporal variation of $SiO_2$, Mg, $NO_3$, and $SO_4$ concentrations indicated that spring water and nearby groundwater were originated from the basaltic aquifer and other groundwater from granitic aquifer. In conclusion, the spring of the Gwanin water intake plant was distinguished from river water in terms of hydrogeochemical characteristics and mainly contributed from the basaltic aquifer.

• Tuberculosis and Respiratory Diseases
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• v.54 no.1
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• pp.22-32
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• 2003

Background : Sputum smears for acid-fast bacilli(AFB) examined microscopically is the most important diagnostic test for pulmonary tuberculosis. However, the AFB observed on the smear may represent either M. tuberculosis or nontuberculous mycobacteria (NTM). This study examined the recovery rate of NTM from the AFB smear-positive sputum specimens in a tertiary hospital in Korea. Materials and Methods : This study analyzed the results for the 1,889 AFB smear-positive and culture-positive sputum specimens collected from 844 patients from July, 1997 to December, 2001. Results : The 1,889 sputum specimens collected from 844 patients tested positive on both microscopy and culture during the 4.5 years. The NTM were recovered from 10.3% (195/1,889) of the smear-positive sputum specimens and 11.0% (93/844) of patients with smear-positive sputum. The NTM were isolated more than two times in 44.1% (41/93) of the patients from whom the NTM was recovered. Trends of the recovery rate of the NTM from the AFB smear-positive sputum specimens were increasing from 6.5%(17/262) in the latter half of 1997 to 17.8%(36/202) in the latter half of 2001 (p<0.001, test for trend). Conclusions : These results suggest that some patients with AFB smear-positive sputum have NTM pulmonary disease rather than pulmonary tuberculosis in Korea.

• Tuberculosis and Respiratory Diseases
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• v.65 no.4
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• pp.292-300
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• 2008

Background: Respiratory failure is a common condition that requires intensive care, and has a high mortality rate despite the recent improvements in respiratory care. Previous reports of patients with respiratory failure focused on the specific disease or included a large proportion of surgical patients. This study evaluated the clinical characteristics, outcomes and prognostic factors of adult patients receiving mechanical ventilation in a medical intensive care unit. Methods: Retrospective chart review was performed on 479 adult patients, who received mechanical ventilation for more than 48 hours in the medical ICU of one tertiary referral hospital. Results: The mean age of the patients was $60.3{\pm}15.6$ years and 34.0% were female. The initial mean APACHE III score was $72.3{\pm}25$. The cause of MV included acute respiratory failure (71.8%), acute exacerbation of chronic pulmonary disease (20.9%), coma (5.6%), and neuromuscular disorders (1.7%). Pressure controlled ventilation was used as the initial ventilator mode in 67.8% of patients, and pressure support ventilation was used as the initial weaning mode in 83.6% of the patients. The overall mortality rate in the ICU and hospital was 49.3% and 55.4%, respectively. The main cause of death in hospital was septic shock (32.5%), respiratory failure (11.7%), and multiorgan failure (10.2%). Males, an APACHE III score >70, the cause of respiratory failure (interstitial lung disease, coma, aspiration, pneumonia, sepsis and hemoptysis), the total ventilation time, and length of stay in hospital were independently associated with mortality. Conclusion: The cause of respiratory failure, severity of the patients, and gender appears to be significantly associated with the outcome of mechanical ventilatory support in patients with respiratory failure.

• The Korean Journal of Nuclear Medicine
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• v.29 no.3
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• pp.332-342
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• 1995

This study was designed to evaluate the effects of various factors on the therapeutic effect of the I-131 labeled anti-carcinoembryonic antigen monoclonal antibody(anti-CEA antibody). Tetrazolium-based colorimetric assay (MTT) was used to compare in vitro cytotoxicity of 3 Korean colon cancer cell lines (SNU-C2A, SNU-C4, SNU-C5) for selection of proper 2 cell lines in this study. The changes of the size of tumor which was xenografted to nude mice (balb/c nu/nu) were compared in 4 groups (group treated I-131 labeled anti-CEA antibody, group treated with non-radiolabeled anti-CEA antibody, group treated with I-131 labeled anti-human chorionic gonadotropin monoclonal antibody (anti-hCG antibody) as nonspecific antibody, and group injected with normal saline as a control). Immunohistochemical staining and in vivo autoradiography were performed after excision of the xenografted tumor. The results were as below mentioned. The in vitro cytotoxic effect of I-131 labeled anti-CEA antibody is most prominent in SNU-C5 cell line between 3 cancer cell lines. The changes of xenografted tumor size in both SNU-C4 and SNU-5S cell tumors at the thirteenth day after injection of the antibodies were smallest in the group treated with I-131 labeled anti-CEA antibody (SNU-C4/SNU-C5; 324/342%) comparing with other groups, group treated with anti-CEA antibody (622/660%), group treated with I-131 anti-hCG antibody (538/546%), and control group(1030/724%)(P<0.02 in SNU-C4 and P<0.1 in SNU-C5 at the 13th day after injection of antibodies). On the thirteenth day after injection of the antibodies nude mice were sacreficed to count the radiouptake of tumor and to check the changes of tumor size. Correlations between radiouptake and change of tumor size were calculated in each groups and significant negative correlation was only obtained in the group treated with I-131 anti-CEA antibody (p<0.05). There were no correlations between antigenic expression of carcinoembryonic antigen and distribution of anti-CEA antibody in both SNU-C4 and SNU-C5 cell tumors on immunoperoxidase staining. On in vivo autoradiography the distributions of anti-CEA antibody were heterogeneous and the intensities of binding were various in SNU-C4 and SNU-C5 cell tumors. It is concluded that I-131 labeled tumor-specific monoclonal antibody, anti-CEA antibody is effective in suppressing the xenografted tumor growth and the effect is influenced by sensitivity of tumor cell itself to the radiolabeled antibody and other local factors instead of specificity of antibody.