• 대한치과기공학회지
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• 제33권3호
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• pp.185-192
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• 2011

Purpose: This study was to evaluate the shear bond strength of the ceramic fused to Ni-Cr alloy(Bellabond plus) and Co-Cr alloy(Wirobond C) by heat treatment. Methods: Metal specimens were divided into 5 groups for each alloy according to heat treatment conditions prior to porcelain application. Fifteen specimens from each group were subjected to a shear load a universal testing machine using a 0.1mm/min cross-head speed and one specimen from each group was observed with EDX line profile. Results: The diffusion of metal oxide observed far in the specimen heat treated than no heat treated in the opaque layer. The shear bond strength measured highest to BP3(50.50MPa), WC2(50.49MPa) groups and measured lowest from BP1(35.1MPaa), WC1(39.66MPa) groups which were not treated with heat, and there was a significant difference (p<0.05). Conclusion: The shear bond strength of Ni-Cr alloy(Bellabond plus) and Co-Cr alloy(Wirobond C) measured similar 5 groups all.

• Molecular & Cellular Toxicology
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• 제5권1호
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• pp.1-6
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• 2009

Microglial cells constitute the first line of defense against infection and injury in the brain. This study was conducted to evaluate the protective mechanisms of Agrimonia pilosa (AP) on LPS-induced activation of BV-2 microglial cells. The effects of AP on gene expression profiles in activated BV-2 microglial cells were evaluated using microarray analysis. BV-2 microglial cells were cultured in a 100 mm dish ($1{\times}10^7/mL$) for 24 hr and then pretreated with 1 g/mL AP or left untreated for 30 min. Next, 1 g/mL LPS was added to the samples and the cells were reincubated at $37^{\circ}C$ for 30 min, 3 hr and 6 hr. The gene expression profiles of the BV-2 microglial cells varied depending on the AP. The microarray analysis revealed that MAPK signaling pathway-related genes were down-regulated and IL10 gene was up-regulated in AP-treated BV-2 microglial cells. AP can affect the inflammatory response and MAPK pathway in BV-2 microglial cells.

• Molecular & Cellular Toxicology
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• 제5권1호
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• pp.44-50
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• 2009

This study was conducted to evaluate the inflammation mechanisms of tumor necrosis factor-$\alpha$ (TNF-$\alpha$), interleukin-4 (IL-4), and IL-$1{\beta}$-induced stimulation of A549 human epithelial cells. In the present study, A549 cells were stimulated with TNF-$\alpha$, IL-4 and IL-$1{\beta}$ to induce expression of chemokines and adhesion molecules involved in eosinophil chemotaxis. The effects of TNF-$\alpha$, IL-4 and IL-$1{\beta}$ on gene expression profiles in A549 cells were evaluated by oligonucleotide microarray and Real time RT-PCR. The gene expression profiles for the A549 cells varied depending on the cytokines. Also, the results of the microarray and Real time RT-PCR revealed that inflammatory-related genes were up-regulated in cytokine stimulated A549 cells. Cytokines can affect inflammation in A549 cells. A microarray-based genomic survey is a high-throughput approach that enables evaluation of gene expression in cytokine stimulated cell lines.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2010년도 춘계학술대회 논문집
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• pp.1656-1662
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• 2010

Automatic train control systems are divided into ATC, ATP and ATS systems etc. The ATP and ATS systems offer discontinuous information for train control. While the ATC systems provide continueous information for train control. There is a method for offering continuous information by AF track circuits. Magnetic fields are formed by current through rails in the AF track circuit systems. So, the continuous information is received by the magnetic fields on a on-board antenna. Coating materials on rails are researched to decrease defects such as head check, shelling, corrugation, squats and so on in Germany. Currently, a coating method of rail construction is proposed by using the ceramics in Korea. When deciding physical characteristic of ceramics, researches are required about variation of flux density by the ceramics. In case that the flux density is much lower than existing value, the information for train control is not transmitted to the on-board antenna. In this paper, inductance on rails is calculated and a model is presented about variation of the magnetic field intensity in the AF track circuit. Standard permeability of ceramics is proposed by analyzing the variation of magnetic field intensity. It is demonstrated by using Maxwell and Matlab program.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2010년도 춘계학술대회 논문집
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• pp.1841-1848
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• 2010

Electric railway system consist of rolling stock, track, signal and streetcar line system. ATP(Automatic Train Protection) system in railway signaling system is the important one grasping the position and velocity of a train. The wayside transmitter of ATP system is installed between rails. Recently, the research about increasing train speed has been developed in total departments of the railroad systems. The study on the information transmission between on-board transmitter and wayside transmitter is required for increasing the train speed in the ATP system. When the train speed is increased as to same transmissi on distance, the problem on information transmission occurs because the transmission time is decreased. In case that the transmission distance is extended, the transmission time is decreased with respect to the train speed. Therefore, we have to define the standard magnetic intensity as to the train speed in order to transmit correctly telegram. In this paper, the transmission distance for the telegram is suggested on the basis of the train speed. Also, the standard magnetic intensity from the wayside transmitter to on-board transmitter is proposed by using transmission distance regarding the train speed in the ERTMS/ETCS system by using Matlab program.

• 음성과학
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• 제11권2호
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• pp.181-192
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• 2004

This paper presents an efficient speech interactive agent rendering smooth car navigation and Telematics services, by employing embedded automatic speech recognition (ASR), distributed speech recognition (DSR) and text-to-speech (ITS) modules, all while enabling safe driving. A speech interactive agent is essentially a conversational tool providing command and control functions to drivers such' as enabling navigation task, audio/video manipulation, and E-commerce services through natural voice/response interactions between user and interface. While the benefits of automatic speech recognition and speech synthesizer have become well known, involved hardware resources are often limited and internal communication protocols are complex to achieve real time responses. As a result, performance degradation always exists in the embedded H/W system. To implement the speech interactive agent to accommodate the demands of user commands in real time, we propose to optimize the hardware dependent architectural codes for speed-up. In particular, we propose to provide a composite solution through memory reconfiguration and efficient arithmetic operation conversion, as well as invoking an effective out-of-vocabulary rejection algorithm, all made suitable for system operation under limited resources.

• Biomolecules & Therapeutics
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• 제26권5호
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• pp.432-438
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• 2018

Worldwide, caffeine is among the most commonly used stimulatory substances. Unfortunately, significant caffeine consumption is associated with several adverse effects, ranging from sleep disturbances (including insomnia) to cardiovascular problems. This study investigates whether treatment with the Evodia rutaecarpa aqueous extract (ERAE) from berries and its major molecular component, evodiamine, can reduce the adverse caffeine-induced sleep-related and excitation effects. We combined measurements from the pentobarbital-induced sleep test, the open field test, and the locomotor activity test in mice that had been dosed with caffeine. We found that ERAE and evodiamine administration reduced the degree of caffeine-induced sleep disruption during the sleep test. Additionally, we found that evodiamine significantly inhibits caffeine-induced excitation during the open field test, as well as decreasing hyperlocomotion in the locomotor activity test. Additional in vitro experiments showed that caffeine administration decreased the expression of ${\gamma}$-aminobutyric acid $(GABA)_A$ receptor subunits in the mouse hypothalamus. However, evodiamine treatment significantly reversed this expression reduction. Taken together, our results demonstrate that ERAE and its major compound, evodiamine, provide an excellent candidate for the treatment or prevention of caffeine-induced sleep disturbances and excitatory states, and that the mechanism of these beneficial effects acts, at least in part, through the $GABA_A$-ergic system.

• 한국자동차공학회논문집
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• 제17권1호
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• pp.176-181
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• 2009

The passenger airbag(PAB) designed for standard sized adults may induce unexpected results to children in out-of-position(OOP) postures. In this work, using MADYMO software, simulations of the OOP injury of children have been performed with respect to PAB design parameters and child dummy positions. The attention is focused on some details with respect to the injury of 3 and 6 year old children in two OOP postures. Among the various design parameters of the passenger airbag systems, four parameters are selected for the sensitivity analysis of the injury with the Taguchi method: bag folding pattern, vent hole size, position of the cover tear seam and the type of door tear seam. An optimal combination of the parameters is suggested.

• Transactions on Electrical and Electronic Materials
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• 제6권6호
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• pp.249-255
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• 2005

In recent years, a novel tiny piezoelectric linear motor converting a radial mode vibration to a longitudinal mode vibration driven by the impact force has been developed for a camera optical module. The tiny piezoelectric motor is consisted of a shaft, mobile element, and piezoelectric transducer. In this work, the frictional coefficient and static friction force of the interface between the shaft and the mobile element have been investigated according to their respective materials. It was found that two combinations, namely Pyrex glass or stainless steel for the shaft and stainless steel (SUS) for the mobile element, exhibited good dynamic behaviors in the tiny ultrasonic linear motor, which was newly developed based on operating concepts based on Newton's law.

• Journal of the Optical Society of Korea
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• 제11권3호
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• pp.138-141
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• 2007

We suggest that supercontinuum can be used for absorption spectroscopy to observe the exciton levels of a semiconductor nano-structure. Exciton absorption spectrum of a GaAs/AlGaAs quantum well was observed using supercontinuum generated by a microstructrured fiber pumped by a femtosecond (fs) pulsed laser. Significantly narrower peaks were observed in the absorption spectrum from 11 K up to room temperature than photoluminescence (PL) spectrum peaks. Because supercontinuum is coherent light and can readily provide high enough intensity, this method can provide a coherent ultra-broad band light source to identify exciton levels in semiconductors, and be applicable to coherent nonlinear spectroscopy such as electromagnetically induced transparency (EIT), lasing without inversion (LWI) and coherent photon control in semiconductor quantum structures.