• 대한한의진단학회지
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• 제22권1호
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• pp.11-18
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• 2018

Objectives The incidence of degenerative diseases is increasing as society ages, and this increased the economic burden on society. Oxidative stress was also under suspicion as one of the causes. Recent studies have found that Curcuma longa Rhizoma had antioxidant, anti-inflammatory, antimutagenic, and anticancer effects. Through this study, we figure out trends in Curcuma longa Rhizoma research and evaluate the therapeutic potential of Curcuma longa Rhizoma for dementia. Methods The search was made using domestic and international internet search sites. "Naver academic," "Google scholar," "Korea institute of oriental medicine (KIOM OASIS)," "Korean traditional knowledge portal (KTKP)," "Library of Congress," "Research information sharing service (RISS)," "National Digital Science Links (NDSL)," and "Pub med" are used to search. The searched for words were "turmeric," "Curcuma longa Rhizoma," "antioxidant," and "nerve regeneration." Results It could be seen that a lot of research done on Curcuma longa recently. In previous studies, the most common research disease was cancer. In previous studies, the most common effects of Curcuma longa was antioxidant and anticancer. Curcumin, Vitamin B1, and various essential oils were the functional components of Curcuma longa Rhizoma. Curcuma longa Rhizoma performs DPPH radical scavenging activity and ABTS radical cation decolorization activity; it inhibits NO and iNOS. Conclusion The destruction of nerve cells due to oxidative stress is a cause of dementia. Curcuma longa Rhizoma have antioxidant effects. Therefore, we believed that it is an effective treatment for dementia. Various studies will be made on Curcuma longa Rhizoma.

• 기본간호학회지
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• 제18권1호
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• pp.116-129
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• 2011

Purpose: The purpose of this study was to develop a computer decision making support system that enables nurses to utilize the computer in selecting the best decision for pain management for patients with dementia institutionalized in nursing homes. Methods: To formulate the protocol for the management of patients' pain, the researcher analyzed content of interviews with 30 nurses in three nursing homes and an expert group. A decision support computer program was formalized based on existing protocols. To evaluate the effectiveness and applicability of the system, analysis of data on patient pain management and nurse satisfaction with the system were done after the formalized decision support computer program was complete. Results: The decision support computer program for pain management for institutionalized patients with dementia was finalized after adjustments following the evaluation. Nurse satisfaction with the program was moderate. It also provided opportunity to reassess thinking about pain and pain management. Conclusions: The results indicate that this program provides nurses with useful knowledge for pain management in institutionalized patients with dementia and aids in decision making in nursing practice in nursing home.

• 대한간호학회지
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• 제52권3호
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• pp.341-358
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• 2022

Purpose: This study examined the effects of a person-centered fall prevention program for older adults with dementia in long-term care hospitals. Methods: A nonequivalent control group pretest-posttest design was used. The study sample included 42 older adults with dementia (experimental group: 21, control group: 21) and 42 caregivers (experimental group: 21, control group: 21). The program comprised 48 sessions held over 12 weeks and included exercise intervention with resistance and balance, dance walking (45~60 min, three times/week), cognitive and emotional intervention (35~50 min, once per week), and person-centered fall prevention education (10 min, once per week). The program for caregivers consisted of six educational sessions (i.e., fall prevention competency enhancement and person-centered care strategy education, 80 min, once per week) for six weeks. Data were collected before participation and 12 weeks after program completion from February 18 to May 12, 2019. Data analysis was conducted using the chi-square test, t-test, and Mann-Whitney U test with SPSS/WIN 21.0. Results: The experimental group of older adults with dementia showed significant improvement in physical and cognitive functions, and a decrease in depression, and behavioral and psychological symptoms, when compared with the control group. caregivers in the experimental group exhibited significant improvement in fall-related knowledge and person-centered care of older adults with dementia compared to the control group. Conclusion: The study findings indicate that this program was effective as a nursing intervention for fall prevention among older adults with dementia in long-term care hospitals.

• 동의생리병리학회지
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• 제28권3호
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• pp.251-262
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• 2014

This article is for understanding dementia with the perspective of Korean Medicine through research on syndrome differentiations of dementia clinically applied and relations between modern diseases and Korean Medicine pattern types of dementia. clinical papers were searched in China Academic Journals(CAJ) of China National Knowledge Infrastructure(CNKI) from 2012 to 2013. Conclusions are as follows. First, dementia was expressed in many ways such as imbecility, stupidity, fatuity, idiocy, vacuity, etc and was related with amnesia, forgetfulness, speech not in the right order, depressive psychosis(quiet insanity), manic psychosis, depression syndrome. Second, prescriptions such as QiFuYin and ZuoGuiWan from JingYueQuanShu, XiXinTang and ZhiMiTang from BianZhengLu, TongQiaoHuoXueTang, XueFuZhuYuTang and BuYangHaiWuTang from YiLinGaiCuo, HaiShaoDan from YiFangJiJie, HuangLianJieDuTang from WaiTaiMiYao were suggested for dementia. Third, syndrome differentiation pattern types of dementia are kidney deficiency and marrow decrease, qi-blood depletion, liver-kidney depletion, spleen-kidney depletion, heart-spleen deficiency as deficiency patterns and effulgent heart-liver fire, ascendant hyperactivity of liver yang, qi stagnation and blood stasis, phlegm turbidity obstructing orifice, phlegm-blood stasis obstructing orifice, intense heat toxin as excess patterns and qi deficiency with blood stasis, yin deficiency with yang hyperactivity as deficiency-excess complex patterns. Major pattern types are kidney deficiency and marrow decrease, phlegm-blood stasis obstructing orifice, qi stagnation and blood stasis, liver-kidney depletion, phlegm turbidity obstructing orifice.

• 한국간호교육학회지
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• 제27권3호
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• pp.306-320
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• 2021

Purpose: This study was a systematic review to assess the contents and effects of an intervention program for family caregivers of the elderly with dementia in Korea. Methods: A literature search was done using Medline, CINAHL, RISS, KISS, and DBpia to identify studies reported in English or Korean from 2000 to 2021. Results: A total of 1,162 articles were searched; finally, 23 articles were used in the analysis based on the inclusion and exclusion criteria. The most applied intervention contents were knowledge provision and emotional support. Fourteen articles (60.9%) reported on complex interventions, including emotional, social support, relaxation, and various activities. The most frequently measured outcome variable in the reviewed literature was "burden," followed by "depression" and "coping strategy." Conclusion: The review results can provide basic data for establishing evidence and suggesting directions of interventions for family caregivers of the elderly with dementia.

• 동의신경정신과학회지
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• 제24권1호
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• pp.123-130
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• 2013

Objectives : During several thousand years, Peucedanum Japonicum Thunberg has been considered as a vegetable side dish in Korea. There is folk knowledge that Peucedanum Japonicum Thunberg prevents vascular disease such as stroke. To identify the effects Peucedanum Japonicum Thunberg, we made up its extract and named it as KH020. Then, we employed common carotid artery ligation (CCAl) surgery for vascular dementia model (VDM), and two types doses of per os (per oral: p.o) treatment. Methods : To confirm prevention and recovery effects for vascular dementia, we treated two doses (100, 400 mg/kg) KH020 in male C57BL/6 mouse during 7 days. After treatment, animals were CCAl operated, and given time to recover. Then, animal were tested in a Y-maze and passive avoidance test. Results : Y-maze results demonstrated that cognition and memory performance were decreased in the VDM group, compared to the sham group. KH020 treatment abolished these effects significantly. The results from the passive avoidance test showed the same phenomenon, but it was not statically significant. Conclusions : Therefore, KH020 prevents the onset of vascular dementia. In future studies, we will evaluate KH020 in regard to alzheimer dementia.

• 농촌의학ㆍ지역보건
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• 제47권4호
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• pp.242-254
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• 2022

본 연구는 농촌지역 치매노인의 삶의 질에 영향을 미치는 요인을 파악하기 위하여 PRECEDE 모형을 적용하여 관련요인들 간의 관계를 분석하여 모형을 구축하고, 모형의 적합도를 검증하고자 하였다. PRECEDE 모형의 단계에 따른 사정요인을 문헌을 참고하여 선정하고, 치매 선별검사를 통하여 치매 진단받은 대상자들을 일대일 면접조사하였다. 연구 결과 치매노인 삶의 질은 건강변인인 우울과 주관적 기억 감퇴 및 의존성에 의해 가장 많은 영향을 받는 것으로 파악되었다. 또한 건강변인에 직접 영향을 미치는 요인은 강화요인인 사회적 지지와 행동요인인 치매예방행위와 건강실천행동으로 파악되었다. 이는 강화요인과 행동요인은 삶의 질에 직접적인 영향을 미치지는 않았지만, 건강에 직접적 영향을 미쳐서 결과적으로 삶의 질에 영향을 주는 간접 영향변수로 확인되었다. 그리고 소인요인인 치매지식, 치매태도, 자기효능감은 행동에 영향을 미치는 요인으로 파악되었다. 즉 PRECEDE 모형의 단계별 요인 중 소인요인, 강화요인, 행동, 건강요인이 연결망을 이루어 삶의 질에 영향을 주는 것으로 확인되었다. 그러나 가능요인은 환경요인에 영향을 미쳤지만 삶의 질에는 영향을 미치지 않았다. 이는 대상자들의 사회적 물리적 환경이 농촌이라는 지역적 소외, 낮은 교육수준과 고령이라는 한계를 반영한 결과라고 생각한다. 그러므로 농촌지역 치매노인의 삶의 질을 향상시키기 위한 간호프로그램 계획 시 PRECEDE 모형을 적용한 다면적인 사정 요인들을 대상자의 특성를 반영하여 포괄적으로 구성할 필요가 있다고 생각한다.

• 동의생리병리학회지
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• 제35권3호
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• pp.104-116
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• 2021

In order to reduce the social and economic costs due to the increase in dementia patients, which is a representative senile disease in an aging society, it will be important to prevent dementia and to detect and treat early in high-risk groups. This study reported the results of treatment for the elderly with high risk of dementia and depression who received Korean medicine (KM) treatment in 9 KM clinics. Medical charts were surveyed on 116 patients with high risk of dementia and depression who received KM treatment at 9 KM clinics in Gangseo-gu from September 1, 2020 to December 31, 2020. The majority of the patients were female(76.72%), the average age was 71.66±7.18 years old, and the average education level was 8.96±3.91 years. The average treatment period was 61.47±10.30 days, the average number of treatments was 15.38±1.06 times, and both acupuncture and herbal medicine were administered. After receiving KM treatment, cognitive assessment scores such as MMSE-DS and MoCA-K, depression-related GDSSF-K score, dementia knowledge, attitude, and preventive behavior, blood debilitation scale, and GQOL-D score were improved compared to before. There was no specific adverse reaction except that one patient with elevated AST and ALT levels was observed. This study showed improvement in cognitive function, depression, dementia-related scale, and quality of life in high-risk groups for dementia and depression over 60 years old who received KM treatment. More systematic and large-scale planned clinical studies will be needed.

• 디지털융복합연구
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• 제19권3호
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• pp.195-202
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• 2021

본 연구는 치매교육으로 제공한 국내·외 가상현실 프로그램의 특성, 효과, 적용 전략 등을 확인하는 체계적고찰 연구이다. 연구방법은 2020년 7월까지 국내·외에서 발표된 문헌을 대상으로 국외는 CINAHL, Cochrane, EMBASE, Pubmed 전자 데이터베이스를 사용하였으며, 국내는 RISS, KISS, DBpia에 대한 검색을 시행하였다. 선정기준과 배제기준을 근거로 최종 6편의 논문이 분석에 사용되었다. 분석결과 선정된 문헌의 연구대상자는 비전문 간병인 2편(33.3%), 일반인 1편(16.7%), 간호학생과 의학 및 약학대 학생을 포함한 학생들 3편(50.0%)이었다. 가상현실 프로그램은 총 5개(공감능력, 치매 지식과 편안감을 포함한 치매태도, 자신의 능력에 대한 신뢰, 양자관계척도)영역에 효과가 있었으며, 이 중 공감능력에 대한 평가가 가장 많았으며 공감능력을 측정한 연구의 75%에서 가상현실 프로그램이 유의한 효과를 나타내었다. 본 연구 결과를 통해 공감을 기반으로 한 인간중심적 간호에 가상현실 기술을 활용할 수 있음을 확인하였다.

• 대한간호학회지
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• 제39권2호
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• pp.166-176
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• 2009

Purpose: The purpose of the study was to identify functional structure and patterns of dialogue sequence in conversations between elderly patients with dementia and nurses in a long-term care facility. Methods: Conversation analysis was used to analyze the data which were collected using video-camera to capture non-verbal as well as verbal behaviors. Data collection was done during February 2005. Results: Introduction, assessment, intervention, and closing phases were identified as functional structure. Essential parts of the conversation were the assessment and intervention phases. In the assessment phase three sequential patterns of nurse-initiated dialogue and four sequential patterns of patient-initiated dialogue were identified. Also four sequential patterns were identified in nurse-initiated and three in patient-initiated dialogues in the intervention phase. In general, "ask question", "advise", and "directive" were the most frequently used utterance by nurses in nurse-initiated dialogue, indicating nurses' domination of the conversation. At the same time, "ask back", "refute", "escape", or "false promise" were used often by nurses to discourage patients from talking when patients were raising questions or demanding. Conclusion: It is important for nurses to encourage patient-initiated dialogue to counterbalance nurse-dominated conversation which results from imbalance between nurses and patients in terms of knowledge and task in healthcare institutions for elders.