• Title/Summary/Keyword: Knowledge flow

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Role of Catheter's Position for Final Results in Intrathecal Drug Delivery. Analysis Based on CSF Dynamics and Specific Drugs Profiles

  • De Andres, Jose;Perotti, Luciano;Villanueva, Vicente;Asensio Samper, Juan Marcos;Fabregat-Cid, Gustavo
    • The Korean Journal of Pain
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    • v.26 no.4
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    • pp.336-346
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    • 2013
  • Intrathecal drug delivery is an effective and safe option for the treatment of chronic pathology refractory to conventional pain therapies. Typical intrathecal administered drugs are opioids, baclofen, local anesthetics and adjuvant medications. Although knowledge about mechanisms of action of intrathecal drugs are every day more clear many doubt remain respect the correct location of intrathecal catheter in order to achieve the best therapeutic result. We analyze the factors that can affect drug distribution within the cerebrospinal fluid. Three categories of variables were identified: drug features, cerebrospinal fluid (CSF) dynamics and patients features. First category includes physicochemical properties and pharmacological features of intrathecal administered drugs with special attention to drug lipophilicity. In the second category, the variables in CSF flow, are considered that can modify the drug distribution within the CSF with special attention to the new theories of liquoral circulation. Last category try to explain inter-individual difference in baclofen response with difference that are specific for each patients such as the anatomical area to treat, patient posture or reaction to inflammatory stimulus. We conclude that a comprehensive evaluation of the patients, including imaging techniques to study the anatomy and physiology of intrathecal environment and CSF dynamics, could become essential in the future to the purpose of optimize the clinical outcome of intrathecal therapy.

A Study on Food Cures for Constipations (대변불통에 활용된 식치방 연구)

  • Hong, Jin-im
    • Journal of Korean Medical classics
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    • v.31 no.1
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    • pp.29-43
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    • 2018
  • Objectives : This paper studies how the people of the past deal with constipation before the introduction of modern medical knowledge. Then, the paper selected some of the methods that use food ingredients with little to no side effects, and studied them to find a basic set of data that can be applied to today's medical practices. Methods : This paper reviewed six literatures: China's Eumsunjungyo, Nonohangeon, and Shiggamboncho, and Chosun's Singnyochanyo, Donguibogam, and Jejungsinpyeon. The food cures related to constipation were studied to discover what ingredients and preparation forms were used, how they were taken, what types of prescriptions existed, and how they were applied. Results : The food cure for constipation included ingredients such as mazi, suzi, sesame, honey, yiyiren, yuliren, xingren, taoren, and rice. These ingredients are known for replenishing the body's fluid and humor and allowing the better flow of qi. Mazi porridge, suma porridge, raw sesame oil, suzhu porridge, and suxing porridge were effective in dealing with the conspitation caused by heat, and jingshen wan, yiyiren porridge, yuliren porridge, yulirenyiyiren porridge, xingren porridge, and taoren porridge were effective in taking care of conspitation caused by qi deficiency. Conclusions : With a constipation caused by heat, it is good to take mazi and spinach regularly which is helpful in cooling down the heat. For senior citizens, constipations occur due to the qi deficiency that leads to the lack of fluid and humor. In this case, suzhu porridge should be taken regularly together with milk and sesame oil in order to replenish the qi. This will tonify the amount of qi and moisten the large intestines, which will be also helpful in tonifying the body itself.

Goal-oriented Geometric Model Based Intelligent System Architecture for Adaptive Robotic Motion Generation in Dynamic Environment

  • Lee, Dong-Hun;Hwang, Kyung-Hun;Chung, Chae-Wook;Kuc, Tae-Yong
    • 제어로봇시스템학회:학술대회논문집
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    • 2005.06a
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    • pp.2568-2574
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    • 2005
  • Control architecture of the action based robot engineering can be divided into two types of deliberate type - and reactive type- controller. Typical deliberate type, slow in reaction speed, is well suited for the realization of the higher intelligence with its capability to forecast on the basis of environmental model according to time flow, while reactive type is suitable for the lower intelligence as it fits to the realization of speedy reactive action by inputting the sensor without a complete environmental model. Looking at the environments in the application areas in which robots are actually used, we can see that they have been mostly covered by the uncertain and unknown dynamic changes depending on time and place, the previously known knowledge being existed though. It may cause, therefore, any deterioration of the robot performance as well as further happen such cases as the robots can not carry out their desired performances, when any one of these two types is solely engaged. Accordingly this paper aims at suggesting Goal-oriented Geometric Model(GGM) Based Intelligent System Architecture which leads the actions of the robots to perform their jobs under variously changing environment and applying the suggested system structure to the navigation issues of the robots. When the robots do perform navigation in human life changing in a various manner with time, they can appropriately respond to the changing environment by doing the action with the recognition of the state. Extending this concept to cover the highest hierarchy without sticking only to the actions of the robots can lead us to apply to the algorithm to perform various small jobs required for the carrying-out of a large main job.

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The Integrated Design and Analysis of Manufacturing Lines (I) - an Automated Modeling & Simulation System for Digital Virtual Manufacturing (제조라인 통합 설계 및 분석(I) - 디지털 가상생산 기술 적용을 위한 모델링 & 시뮬레이션 자동화 시스템)

  • Choi, SangSu;Hyeon, Jeongho;Jang, Yong;Lee, Bumgee;Park, Yangho;Kang, HyoungSeok;Jun, Chanmo;Jung, Jinwoo;Noh, Sang Do
    • Korean Journal of Computational Design and Engineering
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    • v.19 no.2
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    • pp.138-147
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    • 2014
  • In manufacturing companies, different types of production have been developed based on diverse production strategies and differentiated technologies. The production systems have become smart, factories are filled with unmanned manufacturing lines, and sustainable manufacturing technologies are under development. Nowadays, the digital manufacturing technology is being adopted and used in manufacturing industries. When this technology is applied, a lot of efforts, time and cost are required and training professionals in-house is limited. In this paper, we introduce e-FEED system (electronic based Front End Engineering and Design) that is the integrated design and analysis system for optimized manufacturing line development on virtual environment. This system provides the functions that can be designed easily using library and template based on standardized modules and analyzed automatically the logistic and capacity simulation by one-click and verified the result using visual reports. Also, we can review the factory layout using automatically created 3D virtual factory and increase the knowledge reuse by e-FEED system.

A Building Method of Designing National Cyber Security Governance Model Through Diagnosis of Operational Experience (정보보안체계 운영경험 진단을 통한 국가 사이버보안 거버넌스 모델 연구 방법)

  • Bang, Kee-Chun
    • Journal of Digital Convergence
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    • v.16 no.6
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    • pp.205-212
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    • 2018
  • This Study aims to propose a new information security governance model design method for streamlining security governance at national strategic level. The research method of this study is to diagnose our operational experience and to derive a new model design method. In the meantime, national information security activities were perceived to be focused on knowledge transfer, and motivation of activities and securing of executive power were weak. As a result, security blind spots and frequent occurrence of large security incidents have become unresolved challenges. National cyber security governance should be grouped together as a whole systematically from the upper policy to the lower level of performance under the responsibility of the national leader. Based on this approach, this study presented the comprehensive framework of Korean security governance model and embodied it into four architectural designs such as vision, goal, process, and performance, thus deriving the foundation for future national governance model design. Further research is needed to diagnose problems in life cycle flow, security policies based on environmental changes, and new frameworks in which all subjects participate.

Correlations of Oil Concentration Prediction during In-line Flow of $CO_2/Oil$ Mixtures (유동중인 $CO_2$냉매와 오일 혼합물의 농도 예측을 위한 상관식)

  • Park, Keun-Seo;Kang, Byung-Ha;Park, Kyoung-Kuhn;Kim, Suk-Hyun
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.19 no.10
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    • pp.718-725
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    • 2007
  • In the general vapor-compression refrigeration system, refrigeration lubricant circulates in refrigeration system with refrigerant. Knowledge of the amount of circulating lubricant is very important to exactly calculate capacity of the refrigeration system. An experimental study was conducted to estimate the oil concentration of a flowing $CO_2/Oil$ mixtures. POE and PAG oil are considered as test lubricants in this study. Performance tests were conducted under simulated liquid conditions for $CO_2/POE$ oil mixture in oil concentration of 0 to 10 weight-percent and $CO_2/PAG$ oil mixture in oil concentration of 0 to 6 weight-percent in the temperature ranges of $-5^{\circ}C\;to\;15^{\circ}C$. The results obtained indicate specific gravity of $CO_2/Oil$ mixture is increased as oil concentration is increased and as temperature of mixture is decreased. Oil concentration correlation of $CO_2/POE$ oil mixture and $CO_2/PAG$ oil mixture is suggested, based on the measurement of specific gravity and temperature. This correlation enable to predict the oil concentration without extraction of the mixture and can be applied for $CO_2/POE$ mixtures and $CO_2/PAG$ mixtures.

A Study on Congestion Toll Pricing: The Case of Beijing, China (혼잡통행료 산정에 관한 연구 - 중국 베이징의 사례 -)

  • Jiang, Xue;Kim, Ho Yeon
    • Journal of the Economic Geographical Society of Korea
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    • v.21 no.2
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    • pp.107-118
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    • 2018
  • Due to the rapid economic development, traffic congestion has become a dire concern in Beijing, China. Levying a congestion toll is seen as the most effective solution to the problem. Building a congestion pricing model is a crucial step in implementing a workable toll scheme. Unlike previous attempts, this study not only covers the theoretical discussion but also considers three practical issues: the speed-density relationship, the value of travel time savings, and the determination of optimal traffic volume. We estimate the speed-density relationship by regression models and the value of travel time saved through survey results. We further suggest a way through which the government could identify the optimal traffic flow by a series of trial-and-errors, without the knowledge of exact road demand structure. Finally, a practical tolling scheme is proposed for Beijing's second ring road along with some policy recommendations.

The Analysis on Fashion Image through Change in Trend - Focusing on Domestic Women's Wear between $2000{\sim}2006$ - (트렌드 변화에 따른 패션이미지 분석 -2000년${\sim}$2006년 국내 여성복을 중심으로-)

  • Park, Yun-A
    • Journal of the Korea Fashion and Costume Design Association
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    • v.10 no.1
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    • pp.145-159
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    • 2008
  • This study has examined the shift in fashion styles in Korea by analyzing trends in fashion environment and fashion image by seasons in Korea to understand the domestic fashion flow from 2000 to 2006. Since 2000, with the well-being trend, polarization of consumption, preference in luxury orientation, and digital revolution, consumers became individualized and detail oriented. They also became smart consumers equipped with information and knowledge in making choice and purchasing products suiting their taste. To satisfy the consumer trend, fashion market also saw changes such as expansion of advanced distribution, totalization of brands, growing of on-line shopping mall, expansion of outdoor-wear market, and formation of masstage(mass+prestage) market. Fashion images in domestic women's wear since 2000 are analyzed as classic, elegant, minimalism, romantic, bohemian & vintage, ethnic, glam, girlish, kidult, sportive, femiculine, military, and lingerie image. Classic, romantic, and bohemian & vintage are the images that were popular throughout 2000 to 2006. Fashion images of domestic women's wear showed changes in three periods: Sportive image was popular in FW 2002; military image in SS 2003 to SS 2005; and femiculine, glam, and minimalism images in FW 2005 to FW 2006. Through information and detail-oriented emotion, the wide-ranging acceptance of global trends, the consumer tendency towards purchasing products quickly and conveniently, the speedy supply of trendy products both on-line and in-store, and the evolution of the fashion market towards providing one-stop shopping and a cultural space, different fashion images have all emerged at the same time in Korea. It looks like this phenomenon is set to continue for a while.

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The Effect of Anchored Instruction on Elementary School Students' Problem-solving in Algorithm Learning (앵커드 수업을 통한 알고리즘 학습이 초등학생의 문제해결력에 미치는 영향)

  • Choi, Seo-Kyung;Kim, Yung-Sik
    • The Journal of Korean Association of Computer Education
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    • v.15 no.3
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    • pp.1-10
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    • 2012
  • The flow of computer education in modern knowledge and information society contains the computer science courses to cultivate the higher-level thinking abilities such as logical thinking skills, creativity, and problem-solving ability of learners. The purpose of this study is to recognize the need to promote the algorithmic thinking power to improve the problem solving ability of learners, to design the algorithm class based on the anchored instruction strategy for elementary school students and to verify the effectiveness. Anchored instruction model and cases are added to the class. Elementary school students were subjects and divided into a control group in which the traditional algorithm teaching method was conducted and an experimental group in which algorithm class was conducted applying anchored instruction. As results, an experimental group has shown improvements on problem solving compared to a control group.

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An Implementation of Mathematics Editor Using SGML Notation (SGML 표기법을 이용하는 수식 편집기의 설계 및 구현)

  • Kim, Tae-Hoon;Hyun, Deuk-Chang;Lee, Soo-Youn
    • The Transactions of the Korea Information Processing Society
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    • v.3 no.5
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    • pp.1082-1092
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    • 1996
  • The design of distrbuted systems is difficult to achieve as the execution patterns of distrbuted systems are typically more complex than those of non- distributed systems. Thus, research toward the development of design methods for distributed systems is quitely needed. As object-oriented systems and distrbuted systems share similar properties, the combination of these two is somehow natural. In this work, a design of distributed systems is introduced. The goal of the method in this paper is to provide assistance to the process of specifying a formal object- oriented specification from graphical representation specification inputs such as data flow diagrams, state transition diagrams and Petri nets. It addresses the extraction of objects, operations and reationshipsfrom the problem domain with emphasis on the specification of the characteristics of distributed systems. This object identification method is supported by a knowledge base that provides for the automated analysis and reasoning about objects and their relationsships. The final object model is represented in a format which provides a formal mechanism for reprsenting the object information.

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