• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2005.10a
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• pp.107-107
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• 2005

• Proceedings of the Korean Information Science Society Conference
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• 2002.10d
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• pp.223-225
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• 2002

MEMS 가속도센서 기술의 발전은 가속도센서를 이용한 사용자 인터페이스 구현에 대한 연구를 촉진시키고 있다. 본 논문에서는 가속도센서를 기반으로 한 휴대폰 단말기를 사용하여, HCI 관점에서 센싱 기술을 소개한다. 이러한 기술은 센서 신호로부터 컴퓨터의 변위량을 계산함으로써 Knock & Mute 와 Tilt & Scroll와 같은 인터페이스를 구현할 수 있다.

• Proceedings of the Korean Society of Crop Science Conference
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• 2020.06a
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• pp.141-141
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• 2020

• Proceedings of the Korean Society of Crop Science Conference
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• 2020.11a
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• pp.109-109
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• 2020

• Proceedings of the Korean Society of Crop Science Conference
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• 2020.11a
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• pp.108-108
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• 2020

• Transactions of the Korean hydrogen and new energy society
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• v.26 no.6
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• pp.560-566
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• 2015

HCCI (Homogeneous Charge Compression Ignition) hydrogen engine has relatively narrower operation range caused by knock occurrence due to the rapid pressure rising by using higher compression ratio. In this study, EGR as one of the countermeasure methods is considered to extend operation range of HCCI hydrogen engine. Also, the effects of hydrogen EGR are compared with the effects of EGR using hydrocarbon fuel. Hydrocarbon EGR is carried out by adding carbon dioxide to exhaust gas of HCCI hydrogen engine. As the results, EGR has positive effects on a HCCI hydrogen engine in reducing rate of pressure rise as same as the other engines used hydrocarbon fuels. However, the effects of hydrogen EGR are better than those of hydrocarbon EGR in decreasing minimum compression ratio and rate of pressure rise. When applying EGR to HCCI hydrogen engine by 20% rate, the rate of pressure rise decreases by 58% and it results in about 48% increase of the operation range in terms of supply energy.

• Nuclear Engineering and Technology
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• v.35 no.5
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• pp.497-505
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• 2003

This paper describes a computational approach to the quantification of primary damage under irradiation and demonstrates the effect of neutron energy spectra on the formation of the displacement cascade. The development of displacement cascades in ${\alpha}-Iron$ has been simulated using the MOLDY code - a molecular dynamics code for simulating radiation damage. The primary knock-on atom energy, key input to the MOLDY code, was determined from the SPECTER code calculation on two neutron spectra. The two neutron spectra include; (i) neutron spectrum in the instrumented irradiation capsule of the high-flux advanced neutron application reactor (HANARO), and (ii) neutron spectrum at the inner surface of the reactor pressure vessel steel for the Younggwang nuclear power plant No.5 (YG 5). Minor differences in the normalized neutron spectra between the two spectra produce similar values of PKA energy, which are 4.7 keV for HANARO and 5.3 keV for YG 5. This similarity implies that primary damage to the components of the commercial nuclear reactors should be well simulated by irradiation in the HANARO. Moreover, the application of the MD calculations corroborates this statement by comparing cascades simulation results.

• Molecules and Cells
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• v.27 no.6
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• pp.689-695
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• 2009

Chemically synthesized small interfering RNAs (siRNAs) can specifically knock-down expression of target genes via RNA interference (RNAi) pathway. To date, the length of synthetic siRNA duplex has been strictly maintained less than 30 bp, because an early study suggested that double-stranded RNAs (dsRNAs) longer than 30 bp could not trigger specific gene silencing due to the induction of non-specific antiviral interferon responses. Contrary to the current belief, here we show that synthetic dsRNA as long as 38 bp can result in specific target gene silencing without non-specific antiviral responses. Using this longer duplex structure, we have generated dsRNAs, which can simultaneously knock-down expression of two target genes (termed as dual-target siRNAs or dsiRNAs). Our results thus demonstrate the structural flexibility of gene silencing siRNAs, and provide a starting point to construct multifunctional RNA structures. The dsiRNAs could be utilized to develop a novel therapeutic gene silencing strategy against diseases with multiple gene alternations such as viral infection and cancer.

• BMB Reports
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• v.36 no.1
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• pp.35-42
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• 2003

Heterocyclic amines (HCAs) are potent mutagens generated during the cooking of meat and fish, and several of these compounds produce tumors in conventional experimental animals. During the past 5 years or so, HCAs have been tested in a number of novel in vivo murine models, including the following: lacZ, lacI, cII, c-myc/lacZ, rpsL, and $gpt{\Delta}$ transgenics, $XPA^{-/-}$, $XPC^{-/-}$, $Msh2^{+/-}$, $Msh2^{-/-}$ and $p53^{+/-}$ knock-outs, Apc mutant mice ($Apc^{{\Delta}716}$, $Apc^{1638N}$, $Apc^{min}$), and $A33^{{\Delta}N{\beta}-cat}$ knock-in mice. Several of these models have provided insights into the mutation spectra induced in vivo by HCAs in target and non-target organs for tumorigenesis, as well as demonstrating enhanced susceptibility to HCA-induced tumors and preneoplastic lesions. This review describes several of the more recent reports in which novel animal models were used to examine HCA-induced mutagenesis and carcinogenesis in vivo, including a number of studies which assessed the inhibitory activities of chemopreventive agents such as 1,2-dithiole-3-thione, conjugated linoleic acids, tea, curcumin, chlorophyllin-chitosan, and sulindac.

• Journal of the Korea Society of Computer and Information
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• v.12 no.6
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• pp.105-113
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• 2007

A gene regulatory network is a network of genes representing how genes influence the activities of other genes. Nowadays from microarray experiments, a large number of measurements on the expression levels of genes are available. One of typical data is the so-called "steady-state model" data measuring the expression levels of other genes after knocking out a particular gene. This paper shows how to reverse engineer a parsimonious gene regulatory network, using these measurement data. Our model considers auto-regulation, which forms a cycle in a genetic network. We also model repressor and enhancer roles of genes. which are not considered in previous known methods.