• 제목/요약/키워드: Klebsiella pneumoniae DT-S

검색결과 1건 처리시간 0.017초

생쥐의 호흡기 감염에 대한 퀴놀론계 항생제 LB20304a의 치료 효과 (In vivo Efficacy of LB20304a against Experimental Respiratory Tract Infection in Mice)

  • 안미정;김무용;백경숙;김인철;곽진환
    • 약학회지
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    • 제40권4호
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    • pp.438-441
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    • 1996

  • The therapeutic activity of LB20304a was examined on experimental respiratory tract infection (RTI) caused by Klebsiella pneumoniae DT-S in mice. A single oral dose of LB 20304a (1.2mg/mouse) showed a rapid bacteriocidal activity in lung tissue at 4,7 and 24h after administration of drug. The in vivo activity of LB20304a was comparable to that of ciprofloxacin against K. pneumoniae infection, although in vitro MIC of LB20304a was four-fold higher than that of ciprofloxacin.

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