• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.3
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• pp.815-818
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• 2003

Various kinds of chinese herbs have been known as to promote growth rate of animals. We investigated the growth promoting effect of the selected plants by using fish and rats as experimental animals. In a preliminary test by using fish, Eleutherococcus senticosus and Artemisia capillasis were found to be effective. Based on this result, we manufactured the mixture of plant extracts and applied this mixture to rice, named as Kiwoomi/sup TM/. When we administered Kiwoomi/sup TM/ to rats, it was found to be effective in growth promotion. Kiwoomi/sup TM/ - administered group showed 49.3% (0.75g/kg B.W.) and 52.3% (1.59/kg.B.W.) growth promotion, respectively. On the other hand, Control group showed 46.2% growth promotion. This growth promotion was supported by increase of GH and IGF-1 level in the Kiwoomi/sup TM/- administered group. From these results, we suggest that this functional rice could be helpful for growing children.

• Journal of Food Hygiene and Safety
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• v.19 no.3
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• pp.112-118
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• 2004

It has been reported that various kinds of chinese herbs have an activity of promote growth rate in both animals and human. To investigate the growth promoting effect of the selected plants, fish and pigs were used as experimental animals. In fish, Eleutherococcus senticosus extract and Artemisia capillasis extract were found to be most effective. And these plant extracts were given to pigs. The result showed that plant extracts-fed pigs were significantly increased their body weight gain at 7.06% of average daily gain, as compared to control. The verify this results, secreted growth hormone (GH)levels and insulin-like growth factor-1 (ICF-1) levels into blood were measured. This result indicated that GH and IGF-1 levels in the blood in plant extracts-fed pigs were higher that those of control. To confirm growth promotion effect on human, we manufactured the mixture of these plant extracts, and coated this mixture onto rice, named as $Kiwoomi^{TM}$. When we administered $Kiwoomi^{TM}$ to elementary students, it was found to be effective in growth promotion. This result showed that $Kiwoomi^{TM}$-treated elementary students significantly increased their growth rate (about 2.14 times), as compared to untreated children. Taken together, it is suggested that this functional rice ($Kiwoomi^{TM}$) might be helpful for growing children without any side effects.