• 제목/요약/키워드: Kinetic analysis

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핵의학 영상과 추적자 동력학 분석법을 이용한 생체기능 정량화 (Quantitation of In-Vivo Physiological Function using Nuclear Medicine Imaging and Tracer Kinetic Analysis Methods)

  • 김수진;김경민;이재성
    • Nuclear Medicine and Molecular Imaging
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    • 제42권2호
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    • pp.145-152
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    • 2008
  • Nuclear medicine imaging has an unique advantage of absolute quantitation of radioactivity concentration in body. Tracer kinetic analysis has been known as an useful investigation methods in quantitative study of in-vivo physiological function. The use of nuclear medicine imaging and kinetic analysis together can provide more useful and powerful intuition in understanding biochemical and molecular phenomena in body. There have been many development and improvement in kinetic analysis methodologies, but the conventional basic concept of kinetic analysis is still essential and required for further advanced study using new radiopharmaceuticals and hybrid molecular imaging techniques. In this paper, the basic theory of kinetic analysis and imaging techniques for suppressing noise were summarized.

COMBUSTION KINETICS OF POLYETHYLENE TEREPHTHALATE

  • Oh, Sea-Cheon;Lee, Dong-Gyu;Kwak, Hyun;Bae, Seong-Youl
    • Environmental Engineering Research
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    • 제11권5호
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    • pp.250-256
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    • 2006
  • The combustion kinetics of poly(ethylene terephthalate) (PET) was studied by the dynamic model which accounts for the thermal decomposition of polymer at any time. The kinetic analysis was performed by a conventional nonisothermal thermogravimetric (TG) technique at several heating rates between 10 and 40 K/min in air atmosphere. The thermal decomposition of PET in air atmosphere was found to be a complex process composed of at least two stages for which kinetic values can be calculated. The combustion kinetic analysis of PET gave apparent activation energy for the first stage of $257.3{\sim}269.9\;kJ/mol$, with a value of $140.5{\sim}213.8\;kJ/mol$ for the second stage. To verify the effectiveness of the kinetic analysis method used in this work, the kinetic analysis results were compared with those of various analytical methods. The kinetic parameters were also compared with values of the pyrolysis of PET in nitrogen atmosphere.

무산소-혐기-호기법에서 유기기질제거와 질산화의 동역학적 해석 (The Kinetic Analysis on Organic Substrate Removal and Nitrification in Anoxic-Anaerobic-Aerobic Process)

  • 채수권
    • 한국물환경학회지
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    • 제23권5호
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    • pp.689-696
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    • 2007
  • Kinetic analysis was important to develope the biological nutrient removal process effectively. In this research, anoxic-anaerobic-aerobic system was operated to investigate kinetic behavior on the nutrient removal reaction. Nitrification and denitrification were important microbiological reactions of nitrogen. The kinetics of organic removal and nitrification reaction have been investigated based on a Monod-type expression involving two growth limiting substrates : TKN for nitrification and COD for organic removal reaction. The kinetic constans and yield coefficients were evaluated for both these reactions. Experiments were conducted to determine the biological kinetic coefficients and the removal efficiencies of COD and TKN at five different MLSS concentrations of 5000, 4200, 3300, 2600, and 1900 mg/L for synthetic wastewater. Mathematical equations were presented to permit complete evaluation of the this system. Kinetic behaviors for the organic removal and nitrification reaction were examined by the determined kinetic coefficient and the assumed operation condition and the predicted model formulae using kinetic approach. The conclusions derived from this experimental research were as follows : 1. Biological kinetic coefficients were Y=0.563, $k_d=0.054(day^{-1})$, $K_S=49.16(mg/L)$, $k=2.045(day^{-1})$ for the removal of COD and $Y_N=0.024$, $k_{dN}=0.0063(day^{-1})$, $K_{SN}=3.21(mg/L)$, $k_N=31.4(day^{-1})$ for the removal of TKN respectively. 2. The predicted kinetic model formulae could determine the predicted concentration of the activated sludge and nitrifier, investigate the distribution rate of input carbon and nitrogen in relation to the solid retention time (SRT).

Kinematic and Kinetic Analysis of the Soft Golf Swing using Realistic 3D Modeling Based on 3D Motion Tracking

  • Kim, Yong-Yook;Kim, Sung-Hyun;Kim, Nam-Gyun
    • 대한의용생체공학회:의공학회지
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    • 제28권6호
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    • pp.744-749
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    • 2007
  • Kinematic and kinetic analysis has been performed for Soft Golf swings utilizing realistic three dimensional computer simulations based on three dimensional motion tracking data. Soft Golf is a newly developed recreational sport in South Korea aimed to become a safe and easy-to-learn sport for all ages. The advantage of Soft Golf stems from lighter weight of the club and much larger area of the sweet spot. This paper tries to look into kinematic and kinetic aspects of soft golf swings compared to regular golf swing and find the advantages of lighter Soft Golf clubs. For this purpose, swing motions of older aged participants were captured and kinematic analysis was performed for various kinematic parameters such as club head velocity, joint angular velocity, and joint range of motions as a pilot study. Kinetic analysis was performed by applying kinematic data to computer simulation models constructed from anthropometric database and the measurements from the participants. The simulations were solved using multi-body dynamics solver. Firstly, the kinematic parameters such as joint angles were obtained by solving inverse dynamics problem based on motion tracking data. Secondly, the kinetic parameters such as joint torques were obtained by solving control dynamics problem of making joint torque to follow pre-defined joint angle data. The results showed that mechanical loadings to major joints were reduced with lighter Soft Golf club.

Comparison of the Cross-Sectional Area of Longus Colli and Muscle Activity of Sternocleidomastoid in Subjects With Forward Head Posture on the Two Craniocervical Flexion Methods

  • Son, Min-chan;Hwang, Ui-jae;Jung, Sung-hoon;Ahn, Sun-hee;Kim, Hyun-a;Kwon, Oh-yun
    • 한국전문물리치료학회지
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    • 제25권2호
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    • pp.62-70
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    • 2018
  • Background: The craniocervical flexion (CCF) exercise is one of the effective exercise in correcting forward head posture (FHP). However, some people with FHP achieve CCF with compensatory movements, for example, low cervical flexion using superficial neck flexors such as the sternocleidomastoid (SCM) muscle. No study has yet investigated whether a dual­pres ure biofeedback unit (D-PBU) method to prevent low cervical flexion would be helpful in performing pure CCF movement. Objects: The purpose of this study was to compare the effects of the CCF using D-PBU method and the traditional CCF method on the cross-sectional area (CSA) of the longus colli muscle (LCM) and the activity of SCM muscle in subjects with FHP. Methods: Twenty­four FHP subjects (male: 16, female: 8) were recruited for this study. All subjects performed CCF using two different methods: the traditional CCF method and the CCF using D-PBU method. The CSA of the LCM was measured via ultrasound, and surface electromyography was used to measure SCM muscle activity. Results: The change in CSA of the LCM was significantly larger during the CCF using D-PBU method ($1.28{\pm}.09$) compared with the traditional CCF method ($1.19{\pm}.08$) (p<.05). The SCM muscle activity using the CCF using D-PBU method ($2.01{\pm}1.97$ %MVIC) was significantly lower than when using the traditional CCF method ($2.79{\pm}2.32$ %MVIC) (p<.05). Conclusion: The CCF using D-PBU method can be recommended for increasing LCM activation and decreasing SCM muscle activity during CCF movement in subjects with FHP.

Effect of Horizontal Adduction Force on Infraspinatus and Deltoid Activities During the Side-Lying Wiper Exercise Using Pressure Biofeedback

  • Kim, Hyun-a;Hwang, Ui-jae;Jung, Sung-hoon;Ahn, Sun-hee;Kim, Jun-hee;Kwon, Oh-yun
    • 한국전문물리치료학회지
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    • 제24권4호
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    • pp.77-83
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    • 2017
  • Background: Shoulder external rotation exercises are commonly used to improve the stabilizing ability of the infraspinatus. Although the side-lying wiper exercise (SWE) is the most effective shoulder external rotation exercise to maximize infraspinatus activity, the effect of adduction force on the infraspinatus and posterior deltoid has not been demonstrated. Objects: This study was conducted to investigate whether horizontal adduction force increases infraspinatus activity and decreases posterior deltoid activity. Methods: Twenty-eight healthy subjects (male: 21, female: 7; $age=23.5{\pm}1.8years$; $height=170.1{\pm}7.4cm$; $weight=69.4{\pm}9.6kg$) were recruited. Subjects were asked to perform the SWE under two conditions: (1) general SWE and (2) SWE with adduction force using pressure biofeedback. Surface electromyography (EMG) signals of the infraspinatus and posterior deltoid were recorded during SWE. Paired t-tests were used to compare the EMG activity of the infraspinatus and posterior deltoid between the two conditions. Results: Posterior deltoid muscle activity was significantly decreased following SWE with adduction force ($7.53{\pm}4.52%$) relative to general SWE ($11.68{\pm}8.42%$) (p<.05). However, there was no significant difference in the infraspinatus muscle activity between the SWE with adduction force ($28.33{\pm}12.16%$) and the general SWE ($26.54{\pm}13.69%$) (p>.05). Conclusion: Horizontal adduction force while performing SWE is effective at decreasing posterior deltoid activity.

생전분을 당공여체로 한 Stevioside의 당전이 반응의 동력학적 해석 (Kinetic Analysis of Transglycosylation Reaction of Stevioside Using Raw Starch as a Glycosyl Donor)

  • 박동찬;백승걸이용현
    • KSBB Journal
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    • 제9권2호
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    • pp.108-114
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    • 1994
  • 분쇄마찰매치 함유 불균일상 효소반응계에서 생전분을 당공여체로 한 stevioside의 당전이 반응의 kinetics에 관한 연구를 수행하였다. 생전분으로부터 CD를 생서하는 과정과 생성된 CD와 stevioside가 random sequenrial bireactant ,echanism으로 반응하여 당전이 equation을 유도하였다. 또한 유도된 반응식의 각종 kinetic constants을 평가하였다. 유도된 반응식을 Runge-Kutta integration법으로 계산하였으며, 계산 결과를 실험치와 비교하여 유도식의 효용성을 검토하였다. 유도된 kinetic equations는 당공여체인 생전분의 농도, stevioside의 농도, 그리고 중간산물인 CD의 농도 변화를 비교적 정획히 표시할 수 있었으며, 고효율 당전이 효소반응기 개발에 활용될 것이다.

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등온 DSC를 이용한 고에너지 물질의 정밀 반응 모델 기법 개발 (Kinetics analysis of energetic material using isothermal DSC)

  • 김유천;박정수;권국태;여재익
    • 한국연소학회:학술대회논문집
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    • 한국연소학회 2015년도 제51회 KOSCO SYMPOSIUM 초록집
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    • pp.219-222
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    • 2015
  • The kinetic analysis of energetic materials using Differential Scanning Calorimetry (DSC) is proposed. Friedman Isoconversional method is applied to DSC experiment data and AKTS software is used for analysis. The frequency factor and activation energy are extracted as a function of product mass fraction. The extracted kinetic scheme does not assume multiple chemical steps to describe the response of energetic materials; instead, multiple set of Arrhenius factors are used in describing a single global step. The proposed kinetic scheme has considerable advantage over the standard method based on One-Dimenaionl Time to Explosion (ODTX). Reaction rate and product mass fraction simulation are conducted to validate extracted kinetic scheme. Also a slow cook-off simulation is implemented for validating the applicability of the extracted kinetics scheme to a practical thermal experiment.

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닫힌사슬과 열린사슬 자세에서 편측상지에 적용된 PNF가 양측 하지의 근 활성도에 미치는 영향 (Effect of Close kinetic chain and Open kinetic chain Position on Proprioceptive Neuromuscular Facilitation Applied to the Unilateral Upper Extremity on the Muscle Activation of Lower Extremity)

  • 한향완;김상수
    • PNF and Movement
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    • 제7권3호
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    • pp.17-27
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    • 2009
  • The purpose of this study was to investigate the effect of close kinetic chain(CKC) and open kinetic chain(OKC) posion on proprioceptive neuromuscular facilitation applied to the unilateral upper extremity on the muscle activation of lower extremity. All subjects were randomly assigned to two groups: open kinetic chain group(n=5),closed kinetic chain group(n=5). All participants were PNF patterns applied on the unilateral upper extremity in all subjects were the kinetic chain(CKC) and open kinetic chain(OKC) posion on flexion/abduction/external rotation. The hold and approximation techniques for the irradiation were applied to end range. All measurements for each subject took the following tests: pre-test, post - test in 4weeks, post-testin 8weeks. EMG data was collected from the vastus medialis, tibialis anterior, biceps femoris, and gastrocnemius muscle of both lower extreamity using surface EMG system, Each EMG value in individual muscle was normalized for maximal voluntary contraction. The data were analyzed using Two-way analysis of variance(ANOVA) with repeated measures to determine the statistical significances. The results of this study are summarized as follows. First, during for close kinetic chain(CKC) and open kinetic chain(OKC) posion on PNF pattern application, all of the %MVIC values of close kinetic chain and open kinetic chain posion increased sign ificantly compared(p<0.05). Second, The close kinetic chain(CKC) and open kinetic chain(OKC) posion on PNF pattern application was significantly increased with in the intervention period(p<.05). Third, there was a no significant open kinetic chain posion on PNF pattern application of sing muscle group with in the intervention period.(p<0.05) there was a significant close kinetic chain posion on PNF pattern application of sing muscle group with with in the intervention period(p<0.05). Forth, interaction of the exercise position and muscle was also significant. Post-hoc tests revealed that the activation levels of vastus medialis muscle and tibialis anterior muscle was higher in the closed kinetic chain position(p<.05). that the activation levels of vastus medialis and gastrocnemius muscle was higher in the open kinetic chain position(p<.05). In conclusion, it was found that the application of PNF patterns to the unilateral upper extremity effect on the muscle activation of lower extremity and both open kinetic chain exercise and closed kinetic chain exercise was significantly increased muscle activity. Further studies are needed to analyzed long term effects and subjects resulting from these changed.

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십자인대 재건술 후 닫힌사슬운동과 열린사슬운동의 효과 (Effect of Closed and Open Kinetic Chain Exercise after Cruciate Ligament Reconstruction)

  • 권순복;이현옥
    • The Journal of Korean Physical Therapy
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    • 제17권3호
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    • pp.297-310
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    • 2005
  • Open kinetic chain exercise has lost favour in rehabilitation after cruciate ligament reconstruction due to concerns that this exercise is harmful to the graft and will be less effective in improving function. Therefore rehabilitation has focused over the past decade on closed kinetic chain exercise. Open kinetic chain and closed kinetic chain exercises were compared for their effects on proprioception, muscle strength and knee instability in the early period of cruciate ligament reconstruction rehabilitation. The study subjects were 14 patients in 28weeks from cruciate reconstruction surgery(11 male, 3 female; mean age = 44.36 years). Closed kinetic chain exercise group used ball, balance pad and air cushion, to perform weightbearing exercises and the open kinetic chain exercise group used elastic rope and N-K table, to perform non-weightbearing exercises. Between tests, subjects trained 5 times per week for 2 weeks. Statistical analysis was by Wilcoxon signed rank test and Mann Whitney U test. In result, this study shows that both open and closed kinetic chain exercise programs lead to an improved muscle strength and Lysholm score. But there was no improvement in proprioception at both exercises. Closed versus open kinetic chain exercise in early period of rehabilitation after cruciate ligament reconstruction surgery do not differ in their effects on knee proprioception, muscle strength and instability. But the effect of closed kinetic chain exercises was showed more improvement than open kinetic chain exercises between pre-post exercises. Therefore further study is required to assess effect of both groups in more long period.

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