• Journal of Advanced Marine Engineering and Technology
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• v.40 no.8
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• pp.704-709
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• 2016

Wave energy generation systems can be divided into oscillating water chamber type, over topping device type and wave activating body type. The wave activating body type converts wave energy to kinetic energy, and the power generation amount increases as the motion of an activating body increases. In this paper, the wave energy convertor consists of a main body, which has an H-shape, and the activating body. These are connected by a bar-type bridge. By the incident wave, when the activating body moves with vertical motion this motion is consequently converted into rotational motion. The twisting moment and angular velocity at a shaft of convertor are calculated according to various conditions of the incident wave and the shape of the activating body. This can be used as a basic idea for determining the design of wave activating body type convertor.

• BMB Reports
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• v.41 no.1
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• pp.48-54
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• 2008

PM0188 is a newly identified sialyltransferase from P. multocida which transfers sialic acid from cytidine 5'-monophosphonuraminic acid (CMP-NeuAc) to an acceptor sugar. Although sialyltransferases are involved in important biological functions like cell-cell recognition, cell differentiation and receptor-ligand interactions, little is known about their catalytic mechanism. Here, we report the X-ray crystal structures of PM0188 in the presence of an acceptor sugar and a donor sugar analogue, revealing the precise mechanism of sialic acid transfer. Site-directed mutagenesis, kinetic assays, and structural analysis show that Asp141, His311, Glu338, Ser355 and Ser356 are important catalytic residues; Asp141 is especially crucial as it acts as a general base. These complex structures provide insights into the mechanism of sialyltransferases and the structure-based design of specific inhibitors.

• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.4
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• pp.912-919
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• 1994

The engine combustion is one of the most important processes affecting performance and emissions. One effective way to improve the engine combustion is to control the motion of the charge inside a cylinder by means of optimum induction system design, because the flame speed is mainly determined by the turbulence at compression(TDC) process in S.I. engine. It is believed that the tumble and swirl motion generated during intake stroke breaks down into small-scale turbulence in the compression stroke of the cycle. However, the exact nature of this relationship is not well known. This paper describes the tumble flow measurements inside the cylinder of a 4-valve S.I. engine using laser Doppler velocimetry(LDV) under motoring(non-firing) conditions. This is conducted on an optically assesed single cylinder research engine under motored conditions at an engine speed of 1000rpm. Three different cylinder head intake port configurations are studied to develop a better understanding the tumble flow generation, development, and breakdown mechanisms.

• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.4
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• pp.920-932
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• 1994

The combustion phenomena of a reciprocating engine is one of the most important processes affecting performance and emissions. One effective way to improve the engine combustion is to control the motion of the charge inside a cylinder by means of optimum induction system design, because the flame speed is mainly determined by the turbulence at compression(TDC) process in S.I. engine. It is believed that the tumble and swirl motion generated during intake breaks down into small-scale turbulence in the compression stroke of the cycle. However, the exact nature of their relationship is not well known. This paper describes cycle resolved LDV measurement of turbulent flow inside the cylinder of a 4-valve engine under motoring(non-firing) conditions, and studies the effect of intake port configurations on the turbulence characteristics using following parameters ; Eulerian temporal autocorrelation coefficient, turbulence energy spectral density function, Taylor micro time scale, integral time scale, and integral length scale.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2001.05a
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• pp.514-520
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• 2001

A 300Wh class flywheel energy storage system using high Tc superconductor bearings(HTC SFES) is being developed by KIMM and KEPRI. HTC SFES consists of a flywheel rotor, superconductor bearings, a motor/generator and its controller, touch-down bearings, vacuum chamber, etc. Stiffness and damping values of superconductor bearings were experimentally estimated to be 67,700N/m and 29Ns/m respectively. The present HTC SFES was designed to have maximum operating speed of 33000 rpm, which is far above 2 rigid body mode critical speeds of 645rpm and 1,275rpm. Leaf-spring type touch-down bearing were utilized to have the system pass safely through the system critical speeds. It has been experimentally verified that the system can run stably up to 28,000 rpm so that HTC SFES is now expected to reach up to its maximum design speed of 33,000rpm without any difficulties. The Halbach array motor & generator has also been proven its effectiveness on transferring electrical energy to a rotaing composite flywheel in kinetic form.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.15 no.1
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• pp.1-8
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• 2002

When a body enters waters, its original kinetic energy or momentum is distributed among the body and surrounding water in the form of added mass. Due to the transfer of the energy or momentum, the bode is subjected to the hydrodynamic impact forces and acceleration. This impact behavior can be an important criterion of submersible vehicle launched to the air. In this paper, based on Life-boat model, an approximate method is proposed for the evaluation of the forces and responses of cylindrical rigid bode by water entry impact. The impact forces are calculated by yon Karman's momentum theory and motion responses the body, especially acceleration, are calculated by a numerical integration of the motion equations derived by hydrodynamic force equilibrium. The proposed method is expected to be a simple but efficient tool lot the preliminary design or motion analysis of a body subjected to water entry impact.

• Journal of the Society of Naval Architects of Korea
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• v.53 no.4
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• pp.266-274
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• 2016

Many researchers have been trying to improve the propulsion efficiency of a propeller. In this study, the numerical analysis is carried out for the POW(Propeller Open Water test) performance of a propeller equipped with an energy saving device called PHVC(Propeller Hub Vortex Control). PHVC is aimed to control the propeller hub vortex behind the propeller so that the rotational kinetic energy loss can be reduced. The unsteady Reynolds Averaged Navier-Stokes(URANS) equations are assumed as the governing flow equations and are solved by using a commercial CFD(Computational Fluid Dynamics) software, where SST k-ω model is selected for turbulence closure. The computed characteristic values, thrust, torque and propulsion efficiency coefficients for the target propeller with and without PHVC and the local flows in the propeller wake region are validated by the model test results of KRISO LCT(Large Cavitation Tunnel). It is concluded from the present numerical results that CFD can be a good promising method in the assessment of the hydrodynamic performance of PHVC in the design stage.

• Nuclear Engineering and Technology
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• v.41 no.3
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• pp.307-318
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• 2009

KAERI (Korea Atomic Energy Research Institute) has developed the GAMMA+ code for a thermo-fluid and safety analysis of a VHTR (Very High Temperature Gas-Cooled Reactor). A key safety issue of the VHTR design is to demonstrate its inherent safety features for an automatic reactor power trip and power stabilization during an anticipated transient without scram (ATWS) accident such as a loss of forced cooling by a trip of the helium circulator (LOFC) or a reactivity insertion by a control rod withdrawal (CRW). This paper intends to show the ATWS assessment capability of the GAMMA+ code which can simulate the reactor power response by solving the point-kinetic equations with six-group delayed neutrons, by considering the reactivity changes due to the effects of a core temperature variation, xenon transients, and reactivity insertions. The present benchmark calculations are performed by using the safety demonstration experiments of the 10 MW high temperature gas cooled-test module (HTR-10) in China. The calculation results of the power response transients and the solid core temperature behavior are compared with the experimental data of a LOFC ATWS test and two CRW ATWS tests by using a 1mk-control rod and a 5mk-control rod, respectively. The GAMMA+ code predicts the power response transients very well for the LOFC and CRW ATWS tests in HTR-10.

• Toxicological Research
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• v.13 no.3
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• pp.237-245
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• 1997

As the development of a pharmaceutical product is a dynamic process which involves continuousfeed-back between non-clinical and clinical studies, the integration of pharmacokinetics into toxicity testing became increasingly important in recent years. Toxicokinetic measurements in the toxicity studies is considered to be an important scientific approach in the interpretation of the toxicology findings and the promotion of rational study design development. Primarily this research project was conducted to determine the systemic exposure achieved in acute toxicity test and its relationship to dose level and the time course of the toxicity study. Acute hepatotoxicity study and its relevant toxicokinetic study in mice were performed using acetarninophen (AA) as a model compound. The correlation between acute hepatotoxicity indices and toxicokinetic parameters following intraperitoneally administration of various dosages of AA in mice was evaluated and discussed minutely in the text. Based on these studies, single-dose toxicity testing of AA including kinetic studies was evaluated in ICR mice for 7 days and interpreted in the text. Our results from the integration of toxicokinetic monitoring into single-dose toxicity study enable to elucidate the relation of the exposure achieved in toxicity study to toxicological findings and assist in the selection of appropriate dose levels for use in repeated-dose toxicity or later studies.

• Journal of Korean Society of Water and Wastewater
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• v.25 no.6
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• pp.907-915
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• 2011

In this study, the SBR and MLE process was performed for a removal of the RO retentate and the nitrogen removal efficiency was evaluated. The inflow-rate of two processes was set a 10 L/day. The SBR process was operated a two cycle as HRT per one cycle was 12hr and the HRT of the anoxic and aerobic tank was respectively 7.5 hr and 16.5 hr. The methanol was injected for an effective denitrificaion owing to a low C/N ratio of the RO retentate. The two processes were effectively performed for nitrogen removal, but the average removal efficiency of the SBR process was about 94.93% better performance than the MLE process. Therefore, the SBR process demonstrated a good performance more than the MLE process for nitrogen removal of the RO retentate. The kinetic of SNR and SDNR was observed respectively 0.051 kg $NH_{3}-N/kg\;MLVSS{\cdot}dayg$ and 0.287 kg ${NO_3}^--N/kg\;MLVSS{\cdot}day$, which will be useful to design for the wastewater treatment system with a RO retentate.