• Proceedings of the Korean Nuclear Society Conference
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• 1996.05b
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• pp.461-466
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• 1996

원전에서 가상적인 중대사고 발생시 격납용기 하부 캐비티에서 고온의 노심용융물과 콘크리트와의 반응시 생성되는 기체의 종류 및 양, 콘크리트 침식율 및 주변 열전달 특성은 중대사고 연구의 쟁점으로 이에 대한 많은 연구가 수행되고 있다. 본 연구에서는 용융 유사물로 고온의 금속 용융물(SS304) 및 Thermite (Fe＋A1$_2$O$_3$)를 영광 3,4호기 원전에 사용한 콘크리트 시편에 부어 침식율, 생성가스 종류 및 주변 열전달 계수를 측정하였고 후에 MELCOR 로드내 MCCI 해석 부분인 CORCON MOD-3 코드와 비교할 계획이다. 본 논문에서는 MCCI scoping test의 실험 장치, 실험 방법 및 곁과를 소개하였다. 약 1$600^{\circ}C$ 의 SUS 304 용융물(10kg)은 충분치 않은 melt superheat와 용융물 이송과정시 열손실로 인해 침식이 거의 일어나지 않았으나, Thermite 실험에서는 측면 및 하부 방향으로 최대 2.7cm/min 의 침식율을 보였으며 하부방향으로의 최대 열유속은 약 3.1MW/$m^2$로 나타났다. 본 연구의 결과 및 실험 기술은 차세대 원전의 중대사고 완화를 위한 원자로 캐비티 설계 실증실험에 응용될 예정이다.

• Journal of Korean Society of Environmental Engineers
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• v.34 no.10
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• pp.694-701
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• 2012

The main purpose of this study is to evaluate of backwash system of hydrodynamic separator filter (HSF) with solar powered submerged pumps. It consists of a photovoltaic solar array, control electronics, battery, and two submersible pump powered by a 12 voltage DC motor. The laboratory scale study on treatable potential of micro particles using backwash HSF that was a combined with perlite filter cartridge and backwash nozzles. Since it was not easy to use actual storm water in the scaled-down hydraulic model investigations, it was necessary to reproduce ranges of particle sizes with synthetic materials. The synthesized storm runoff was made with water and addition of particles; ion exchange resin partices, silica gel particles, and commercial area manhole sediment particles. HSF was made of acryl resin with 250 mm of diameter filter chamber and overall height of 800 mm. Four case test were performed with different backwashing conditions and determined the SS removal efficiency with various surface loading rates. The operated range of surface loading rate was about 308~$1,250m^3/m^2/day$. It was found that SS removal efficiency of HSF using two submersible pumps improved by about 18% compared with HSF without backwash. Nonpoint control devices with solar water pumping systems would be useful for backwashing the filter in areas with not suppling electricity and reduce filter media exchange cost.

• Journal of Korean Society of Environmental Engineers
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• v.29 no.12
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• pp.1353-1359
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• 2007

Water quality constituents, and particle size distributions were characterized in urban bridge road runoff, Bridge road runoff contains significant loads of micro-particles, heavy metals and organic constituents. Bridge road runoff was monitored on four sites of four and six lanes bridge road areas along with traffic volume. A total seven storm events were monitored to characterize the bridge road runoff. The quantity of road runoff and quality constituents, including chemical oxygen demand(COD), suspended solids(SS), total nitrogen(T-N), ortho-phosphorus$(PO_4-P)$, total phosphorus(T-P), and particle size distribution were analyzed. The results indicate that the concentrations of SS, COD, T-N and T-P ranges were $35\sim2,390$ mg/L, $40\sim1,274$ mg/L, $0.03\sim21.25$ mg/L, and $0.05\sim4.58$ mg/L, respectively. And the results showed that the mean range of particle size and $D_{90}$ for bridge road runoff were $4.75\sim14.05{\mu}m$ and $17.33\sim58.15{\mu}m$, respectively.

• Development and Reproduction
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• v.15 no.2
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• pp.179-185
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• 2011

Some phytoestrogens in soy and red wine, for example, might have beneficiary rather than adverse effects. In particular, dietary soy intake seems to be highly correlated with protection of breast cancer, osteoporosis and cardiovascular disorders. However, questions persist on the potential adverse effects of the main soy constituent genistein (GS) on female reproductive physiology. Previously we found that prepubertal exposure to GS could activate the reproductive system of immature female rats leading to precocious puberty onset, and intracerebroventricularly (ICV) injected GS could directly activate hypothalamic kisspeptin-GnRH neuronal circuits in adult female rats. The present study was performed to examine the hypothalamus-specific GS effects in prepubertal female rats and which subtype of estrogen receptor is mediated in this GS effect. Prepubertal female rats (PND 30) were anaesthetized, treated with single dose of GS (3.4 ${\mu}g$/animal), and sacrificed at 2 hrs post-injection. To determine the transcriptional changes of reproductive hormone-related genes in hypothalamus, total RNAs were extracted and applied to the semi-quantitative reverse transcription polymerase chain reaction (RT-PCR). ICV infusion of GS significantly lowered the transcriptional activities of mTOR (1:$0.361{\pm}0.058$ AU, p<0.001) but increased that of GAD67 (1:$1.285{\pm}0.099$ AU, p<0.05), which are known to act as an upstream modulator of kisspeptin and GnRH neuronal activities in the hypothalamus, respectively. GS administration enhanced significantly the mRNA levels of KiSS-1(1:$1.458{\pm}0.078$ AU, p<0.001), and exerted no effect on the mRNA level of kisspeptin receptor GPR-54 (1:$1.29{\pm}0.08$ AU). GnRH gene expression was significantly decreased in GS-treated group compared to control group (1:$0.379{\pm}0.196$ AU, p<0.05). There was no difference in the mRNA level of $ER{\alpha}$ in the GS-treated group compare to control group (1:$1.180{\pm}0.390$ AU, Fig. 3A). However, icv infusion of GS significantly increased the transcriptional activities of $ER{\beta}$ (1:$4.209{\pm}0.796$ AU, p<0.01, Fig. 3B). Taken together, the present study indicated that the acute exposure to GS could directly alter the hypothalamic GnRH modulating system in prepubertal female rats. Our study strongly suggested the involvement of $ER{\beta}$ pathway in GS's hypothalamus-specific action, and this idea is consistent with the GS's well-known $ER{\beta}$-mediated protective action in breast cancer.

• Journal of Korean Society of Environmental Engineers
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• v.28 no.1
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• pp.42-47
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• 2006

The biological nutrient treatment is formed with repetition and rearrangement of anaerobic, anoxic and oxic tank. In this case, VFAs is generated in the anaerobic tank and the anoxic tank. The VFAs is an important factor for removal of nitrogen and phosphate and SVI. So, in this study I investigated to find a relationship among the generation rate of the VFAs according to the change of F/M ratio and the characteristic which can eliminate organic matter and nitrogen according to the change of residual concentration of the VFAs and the efficiency of the process and also SVI in wastewater treatment. $A^2/O$ process was used for wastewater treatment. F/M ratio was under the control of the change of MLSS concentration. When the F/M ratio was changed from 0.16 to 0.08 kg-BOD/kg-MLSS/day, the VFAs's production volume increased based on the reduction of F/M ratio in batch reaction. And the residual concentration of the VFAs decreased at first and then increased later. SVI and SS were high when F/M ratio was $0.16kg/kg{\cdot}d$ and showed stable status when F/M ratio decreased $0.11{\sim}0.13kg/kg{\cdot}d$. However, SVI and SS continuously increased with decrease of F/M ratio and were high at $0.08kg/kg{\cdot}d$. In the result of comparison between residual concentration of the VFAs and denitrification rate in anoxic tank, the less residual volume of the VFAs was in anoxic tank, the higher denitrification ratio became. The optimal residual-concentration of the VFAs considering SVI and removal efficiency of nitrogenwas $1.4{\sim}2.2mg/L$. At that time F/M ratio was $0.11{\sim}0.13$ kg-BOD/kg-MLSS/day.

• Culinary science and hospitality research
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• v.13 no.1 s.32
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• pp.119-128
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• 2007

Volatile flavor compounds of sauces made from shrimps, crabs or lobsters were analyzed by the combination of canister system, gas chromatography(GC) and mass selective detector(MSD). Of 72 total volatile compounds from 4 kinds of sauces, 45 compounds were identified from shrimp sauce(SS). Ten alkanes, 5 ketones, 3 aldehydes were obtained from SS. Especially, 3-methyl-2-butanone, 2-pentanamine, isobutane, 3-methyl-2-butanol, carbon disulfide and dimethyl sulfide were predominant compounds in SS. In crab sauce(CS), there were 18 compounds identified, including 4 alcohols, 4 alkanes, 3 aldehydes, 2 ketones, acid and amine. 2-Methoxy ethanol, trimethyloxirane and 3-buten-1-ol were special volatile compounds in CC. Volatile compounds from lobster head sauce(LHS) or lobster shell sauce(LSS) were 16 or 18 kinds respectively. The major volatile compounds of LHS were formic acid, 1-propanethiol, $\beta$-pinene and allyl sulfide, and those of LSS were acids, pentane, 3-methyl-1-butanol and 2,4-dimethyl-3-pentanone. It was thought that the volatile compounds identified from sauces as well as shrimps, crabs or lobsters might come from wine, onions, bay leaves or celery used as minor ingredients.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.344-344
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• 2016

최근 도시화에 따른 투수면적의 감소인한 우수 유출량의 증가로 비점오염 및 도시 침수피해에 대한 문제가 증가하고 이에 따른 유역관리에 대한 관심이 높아지고 있다. 불투수면적의 특성으로 인한 도시 비점오염의 축적량 증가와 함께 적은 강우에도 유출이 발생되고 이로 인한 세척효과에 의해 고농도의 비점오염원을 하천으로 유출시키게 된다. 이러한 우수 유출 및 비점오염원 관리방안으로 저영향개발(LID;Low Impact Development) 기법에 의한 우수유출량의 저감과 수질개선효과를 연구할 필요가 있다. 따라서 본 연구에서는 전주시 송천동 지역을 대상으로 관측자료를 이용하여 SWMM모형을 구축하였고, 그 결과를 바탕으로 LID기법 중 하나인 Bioretention과 저류조용량(900, 1050, 1200, $1350m^3$)을 고려한 수질개선 효과를 분석하였다. 송천동 지역에 대한 저류조 및 Bioretention 적용에 따른 수질 개선효과를 비교한 결과 SS는 무시설의 경우 평균 100.08mg/L에서 1) 저류조의 경우 83.40mg/L(17% 감소), 2) 식생저류지의 경우 86.27mg/L(14% 감소), 3) 저류조와 식생저류지 연계 적용의 경우 79.43mg/L(21% 감소)로 평가되었다. BOD는 무시설의 경우 평균 15.24mg/L에서 1) 저류조의 경우 13.37mg/L(12% 감소), 2) 식생 저류지의 경우 12.29mg/L(19% 감소), 3) 저류조와 식생저류지 연계 적용의 경우 11.81mg/L(22% 감소)로 나타났다. T - P는 무시설의 경우 평균 1.09mg/L에서 1) 저류조의 경우 0.96mg/L(12% 감소), 2) 식생저류지의 경우 0.84mg/L(22% 감소), 3) 저류조와 식생저류지 연계 적용의 경우 0.78mg/L(28% 감소)로 수질이 개선되었다. 저류조와 식생저류지 적용에 따른 SS의 경우, 식생저류지를 적용했을 경우보다 저류조를 적용했을 경우 수질농도가 더 많이 저감되는 것으로 산정되었다. BOD와 T - P의 경우 저류조를 적용했을 경우보다 식생저류지를 적용했을 경우 수질농도가 저감 되는 것으로 나타났다. 또한 저류조와 식생저류지를 연계 적용했을 경우 각각 적용했을 경우보다 수질농도가 더 많이 저감되는 것으로 평가되며, 향후 유역 내 LID기법과 저류조 위치에 따른 효과에 대한 연구가 필요하다.

• The Journal of Korean Medicine
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• v.30 no.1
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• pp.120-127
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• 2009

Objectives: Sahyangsohapwon (SS) is a herbal medication that has been widely used with circulatory and neural diseases. This study was conducted to assess the effect of SS on the autonomic nervous system by using heart rate variability measurement. Methods: The eligible subjects were enrolled from the healthy male group of ages 20 to 35 years. They were divided into two groups, the SS group (n=26) and the control (n=24). We monitored the ECG of subjects from the time period 14:00 to 18:00. In the SS group, subjects were administered with a dose of SS at the time 15:00, whereas the control group had none. For each hour HRV measurement was monitored every 15 minutes for 512 seconds from the time period 14:00 to 18:00. The mean value, which was calculated using the 4 values during each hour (i.e. 14:00, 14:15, 14:30, 14:45), was used as the representative value for each individual hour. For the measurement values, RR-interval and SDNN (standard deviation of the NN intervals) were used as time domain analysis, and HF (high frequency), LF (low frequency), and LF/HF ratio were used as frequency domain analysis. Results: The LF value showed an increase after one hour of SS administration and showed gradual diminution for each and every hour. The repeated measures of ANOVA for the comparison of the LF value between the SS group and the control group showed significant differences. While, RR interval, SDNN, HF, and LF/HF ratio values showed no significant differences between the two groups. Conclusions: We suggest that the SS might be useful for stabilizing autonomic nervous system by inhibiting sympathetic nerve activation in healthy people.

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.12
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• pp.1836-1843
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• 2019

Objective: Social genetic effects (SGE) are an important genetic component for growth, group productivity, and welfare in pigs. The present study was conducted to evaluate i) the feasibility of the single-step genomic best linear unbiased prediction (ssGBLUP) approach with the inclusion of SGE in the model in pigs, and ii) the changes in the contribution of heritable SGE to the phenotypic variance with different scaling ${\omega}$ constants for genomic relationships. Methods: The dataset included performance tested growth rate records (average daily gain) from 13,166 and 21,762 pigs Landrace (LR) and Yorkshire (YS), respectively. A total of 1,041 (LR) and 964 (YS) pigs were genotyped using the Illumina PorcineSNP60 v2 BeadChip panel. With the BLUPF90 software package, genetic parameters were estimated using a modified animal model for competitive traits. Giving a fixed weight to pedigree relationships (${\tau}:1$), several weights (${\omega}_{xx}$, 0.1 to 1.0; with a 0.1 interval) were scaled with the genomic relationship for best model fit with Akaike information criterion (AIC). Results: The genetic variances and total heritability estimates ($T^2$) were mostly higher with ssGBLUP than in the pedigree-based analysis. The model AIC value increased with any level of ${\omega}$ other than 0.6 and 0.5 in LR and YS, respectively, indicating the worse fit of those models. The theoretical accuracies of direct and social breeding value were increased by decreasing ${\omega}$ in both breeds, indicating the better accuracy of ${\omega}_{0.1}$ models. Therefore, the optimal values of ${\omega}$ to minimize AIC and to increase theoretical accuracy were 0.6 in LR and 0.5 in YS. Conclusion: In conclusion, single-step ssGBLUP model fitting SGE showed significant improvement in accuracy compared with the pedigree-based analysis method; therefore, it could be implemented in a pig population for genomic selection based on SGE, especially in South Korean populations, with appropriate further adjustment of tuning parameters for relationship matrices.

• Clinical and Experimental Pediatrics
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• v.59 no.4
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• pp.190-195
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• 2016

Purpose: Severe aplastic anemia (SAA), a fatal disease, requires multiple transfusion, immunosuppressive therapy, and finally, hematopoietic stem cell transplantation (HSCT) as the definitive treatment. We hypothesized that iron overloading associated with multiple transfusions and HSCT-related complications may adversely affect cardiac function. Left ventricular (LV) function was assessed in children after HSCT for SAA. Methods: Forty-six consecutive patients with a median age of 9.8 years (range, 1.5-18 years), who received HSCT for SAA and who underwent comprehensive echocardiography before and after HSCT, were included in this study. The data of LV functional parameters obtained using conventional echocardiography, tissue Doppler imaging (TDI), and speckle-tracking echocardiography (STE) were collected from pre- and post-HSCT echocardiography. These data were compared to those of 40 age-matched normal controls. Results: In patients, the LV ejection fraction, shortening fraction, end-diastolic dimension, mitral early diastolic E velocity, TDI mitral septal E' velocity, and STE LV longitudinal systolic strain rate (SSR) decreased significantly after HSCT. Compared to normal controls, patients had significantly lower post-HSCT early diastolic E velocity and E/A ratio. On STE, patients had significantly decreased LV deformational parameters including LV longitudinal systolic strain (SS), SSR, and diastolic SR (DSR), and circumferential SS and DSR. Serum ferritin levels showed weak but significant correlations (P<0.05) with LV longitudinal SS and SSR and circumferential SS and DSR. Conclusion: Subclinical LV dysfunction is evident in patients after HSCT for SAA, and was associated with increased iron load. Serial monitoring of cardiac function is mandatory in this population.