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Diagnostic Approach to a Soft Tissue Mass (연부조직 종양의 진단적 접근)

  • Chun, Young Soo;Song, Seung Hyun
    • Journal of the Korean Orthopaedic Association
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    • v.54 no.4
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    • pp.293-301
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    • 2019
  • Soft tissue masses of the extremities and torso are a common problem encountered by orthopaedic surgeons. Although these soft tissue masses are often benign, orthopaedic surgeons need to recognize the key features differentiating benign and malignant masses. An understanding of the epidemiology and clinical presentation of soft tissue masses is needed to develop a practical approach for evaluation and surgical management. Size and depth are the two most important factors on which triage decisions should be based. In a differential diagnosis of a tumor, it is important to know the characteristics of the soft tissue mass through detailed history taking and physical examinations before the diagnostic procedures. A variety of imaging studies, such as simple radiography, ultrasound, magnetic resonance imaging, positron emission tomography, computed tomography, bone scan, and angiography can be used to diagnose tumors. Know the ledge of advantages and disadvantages of each imaging study is essential for confirming the characteristics of the tumor that can be observed in the image. In particular, ultrasonography is convenient because it can be performed easily in an outpatient clinic and its cost is lower than other image studies. On the other hand, the accuracy of the test is affected by the skill of the examiner. A biopsy should be performed to confirm the tumor and be performed after all imaging studies have been done but before the final treatment of soft tissue tumors. When a biopsy is to be performed, careful attention to detail with respect to multidisciplinary coordination beforehand, cautious execution of the procedure to minimize complications, and expedient follow-up and referral to a musculoskeletal oncologist when appropriate, are essential.

A Research on Improving the Shape of Korean Road Signs to Enhance LiDAR Detection Performance (LiDAR 시인성 향상을 위한 국내 교통안전표지 형상개선에 대한 연구)

  • Ji yoon Kim;Jisoo Kim;Bum jin Park
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.22 no.3
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    • pp.160-174
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    • 2023
  • LiDAR plays a key role in autonomous vehicles, and to improve its visibility, it is necessary to improve its performance and the detection objects. Accordingly, this study proposes a shape for traffic safety signs that is advantageous for self-driving vehicles to recognize. Improvement plans are also proposed using a shape-recognition algorithm based on point cloud data collected through LiDAR sensors. For the experiment, a DBSCAN-based road-sign recognition and classification algorithm, which is commonly used in point cloud research, was developed, and a 32ch LiDAR was used in an actual road environment to conduct recognition performance tests for 5 types of road signs. As a result of the study, it was possible to detect a smaller number of point clouds with a regular triangle or rectangular shape that has vertical asymmetry than a square or circle. The results showed a high classification accuracy of 83% or more. In addition, when the size of the square mark was enlarged by 1.5 times, it was possible to classify it as a square despite an increase in the measurement distance. These results are expected to be used to improve dedicated roads and traffic safety facilities for sensors in the future autonomous driving era and to develop new facilities.

A Study on Acceptance of Blockchain-Based Genetic Information Platform (블록체인 기반 유전자분석 정보플랫폼의 수용에 대한 연구)

  • In Seon Choi;Dong Chan Park;Doo Hee Chung
    • Information Systems Review
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    • v.23 no.3
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    • pp.97-125
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    • 2021
  • Blockchain is a core technology to solve personal information leakage and data management issues, which are limitations of existing Genomic Sequencing services. Due to continuous cost reduction and deregulation, the market size of Genomic Sequencing has been increasing, also the potential of services is expected to increase when Blockchain's security and connectivity are combined. We created our research model by combining the Technology Acceptance Model (TAM) and the Innovation Resistance Theory also analyzed the factors affecting the acceptance intention and innovation resistance of the Blockchain Based Genomic Sequencing Information Platform. A survey was conducted on 150 potential users of Blockchain and Genomic Sequencing services. The analysis was conducted by setting the four Blockchain variables: Security, transparency, availability, and diversity). Also, we set the Perceived Usefulness, Perceived risk, and Perceived Complexity for Technology Acceptance and Innovation Resistance variables and analyzed the effect of the characteristics of the Blockchain on acceptance intention and innovation resistance through these variables. Through this analysis, key variables that need to be considered important to reduce resistance and increase acceptance intention could be identified. This study presents innovation factors that should be considered in companies preparing a new Blockchain Based Genomic Sequencing Information Platform.

Recent Understanding in Particular Matter-Mediated Aging and Age-Related Diseases (미세먼지에 의한 노화 및 노화 관련 질병에 대한 최근 연구 동향)

  • EunJin Bang;Yung Hyun Choi
    • Journal of Life Science
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    • v.34 no.1
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    • pp.68-77
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    • 2024
  • Airborne particulate matter (PM) is an environmentally hazardous pollutant that originates from various sources. PM is comprised of solid particles and liquid droplets of diverse composition and size. Hazardous chemical compositions of PM include elemental and organic carbon, organic compounds, biological compounds and metals. Upon acute and chronic PM exposure, toxic contaminants enter and accumulate within physiological systems and prompt cell structure changes accompanied with intracellular endoplasmic reticulum stress, mitochondrial dysfunction, oxidative stress, inflammation, lipid accumulation, and cell cycle arrest. Ultimately, these cellular response leads to the development of key characteristics of aging. In addition, PM internalization enhances autophagy reflux and lysosomal dysfunction, which is involved in cell aging. Previous studies have emphasized a positive association between PM and increased mortality or decreased lifespan, although these are evidenced mostly by observational studies. Direct evidence of the link between PM and aging is still limited. This review evaluates the evidence from not only observational studies but also in vitro and in vivo evidence of PM on aging progression and age-related diseases development. This evidence is based on age-associated cellular changes including endoplasmic reticulum stress, mitochondrial dysfunction, oxidative stress, inflammation, adipose accumulation, autophagy, which strengthen the association between PM exposure and aging. Understanding the underlying cellular responses under PM may allow for the development of new therapeutic targets for PM-induced aging.

An Empirical Analysis of In-app Purchase Behavior in Mobile Games (모바일 게임 인앱구매에 영향을 주는 요인에 관한 연구)

  • Moonkyoung Jang;Changkeun Kim;Byungjoon Yoo
    • Information Systems Review
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    • v.22 no.2
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    • pp.43-52
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    • 2020
  • The mobile game industry has become the one of the fastest growing industries with its astonishing market size. Despite its industrial importance, a few studies empirically considered actual purchasing behavior in mobile games rather than the intention to purchase. Therefore, this paper investigates the key drivers of in-app purchase by analyzing the game-log dataset provided from a mobile game company in Korea. Specifically, the effects of goal-directed, habitual and social-interacted playing behavior are analyzed on in-app purchase. Furthermore, the recursive relationship with playing and purchasing behaviorsis also considered. The result shows that all suggested factors have positive impacts on in-app purchase in the current period. In addition, the effect of previous habitual playing has a positive impact, but the effect of social-interacted playing and in-app purchase in the previous period have negative impacts on in-app purchase of the current period. These findings can improve our understanding of the impact of game playing on in-app purchase in mobile games, and provide meaningful insights for researchers and practitioners.

Diagnostic Imaging of Biliary Atresia (담도폐쇄증의 영상 진단)

  • Haesung Yoon;Hyun Ji Lim;Jisoo Kim;Mi-Jung Lee
    • Journal of the Korean Society of Radiology
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    • v.83 no.5
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    • pp.991-1002
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    • 2022
  • Biliary atresia is a rare but significant cause of neonatal cholestasis. An early and accurate diagnosis is important for proper management and prognosis. To diagnose biliary atresia, various imaging studies using ultrasonography, MRI, hepatobiliary scans, and cholangiography can be performed, although ultrasonography is more important for initial imaging studies. In this article, we review the findings of biliary atresia from various imaging modalities, including ultrasonography, MRI, hepatobiliary scans, and cholangiography. The known key imaging features include abnormal gallbladder size and shape, periportal thickening visible as a 'triangular cord' sign, invisible common bile duct, increased hepatic arterial flow, and combined anomalies. Aside from the imaging findings of biliary atresia, we also reviewed the diagnostic difficulty in the early neonatal period and the role of imaging in predicting hepatic fibrosis. We hope that this review will aid in the diagnosis of biliary atresia.

Residential Independence of Youth and Policy Implications (청년의 주거독립에 미치는 영향과 정책적 시사점)

  • Yoonhye Jung;Jinuk Sung
    • Land and Housing Review
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    • v.15 no.2
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    • pp.39-56
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    • 2024
  • This study addressed housing issues among various social problems of youth. With a focus on residential independence, this study analyzed the factors that lead youth to achieve residential independence. This study drew on nationwide data from the 'Youth Life Survey (2022)' with a sample size of 12,578. Binary logistic regression analysis was employed, with the dependent variable being residential independence. Key factors were as follows. The probability of residential independence was higher for men than women. Residential independence occurred mainly in non-metropolitan areas compared to metropolitan areas. Findings revealed that greater age, income, and assets facilitate achieving residential independence. In addition, public transport and cultural facilities were important for their residential independence, and it was found that the previous experience of residential independence had a positive effect. Policy implications derived from the findings are as follows. It is required to consider the heterogeneity and diversity of youth rather than implementing unitary policies. To ensure continuity and sustainability of self-reliance, long-term support programs are needed rather than temporary support. Moreover, it is required to offer public support comprehensively, instead of youth relying on support from personal networks, including their parents. An inclusive housing policy should be established to support youth for their residential independence in the future.

Fulfilling the Export Potential of Agricultural Production in the Context of Aggravating Global Food Crisis

  • Hassan Ali Al-Ababneh;Ainur Osmonova;Ilona Dumanska;Petro Matkovskyi;Andriy Kalynovskyy
    • International Journal of Computer Science & Network Security
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    • v.24 no.7
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    • pp.128-142
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    • 2024
  • Creation and implementation of export-oriented strategy is an urgent issue of economic development of any country. In an export-oriented model of economic development, exports should be a means of promoting economic growth and a tool to strengthen existing and potential competitive advantages. Agricultural production is the key factor in exports and the source of foreign exchange earnings in many countries. However, the export potential of agricultural producers may be inefficiently fulfilled due to the heterogeneity of countries in terms of economic development, trade relations and border policy. The aim of the research is to study the nature, main trends and problematic aspects of fulfilling the export potential of agricultural production in the context of aggravating food crisis. The study involved general scientific methods (induction and deduction, description, analysis, synthesis, generalization) and special (statistical method, economic analysis, descriptive statistics and interstate comparisons, graphical method). The need to ensure food security by countries around the world urges the importance of the agricultural sector as a catalyst for economic development, sources of foreign exchange earnings, investment direction, etc. The study of agricultural specialization led to the conclusion that wheat and sugar are goods with the highest export potential. It is substantiated that the countries of South America, OECD, North America and Europe have the highest level of realization of export potential of agricultural production, and African countries are import-dependent. In addition, the low export orientation of Africa and Asia due to the peculiarities of their natural and climatic conditions is established based on the assessment of export-import operations in the regional context. The internal and external export potential of each of the regions is analysed. Economic and mathematical simulation of assessing the impact of the most important factors on the wheat exports volumes was applied, which allowed predicting wheat exports volume and making sound management decisions regarding the realization of the export potential of agricultural companies. The inverse correlation between the exports volume and wheat consumption per capita, and the direct correlation between the effective size and area of land used for wheat cultivation was established through the correlation and regression analysis.

A Study of Feasibility of Dipole-dipole Electric Method to Metallic Ore-deposit Exploration in Korea (국내 금속광 탐사를 위한 쌍극자-쌍극자 전기탐사의 적용성 연구)

  • Min, Dong-Joo;Jung, Hyun-Key;Park, Sam-Gyu;Chon, Hyo-Taek;Kwak, Na-Eun
    • Geophysics and Geophysical Exploration
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    • v.11 no.3
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    • pp.250-262
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    • 2008
  • In order to assess the feasibility of the dipole-dipole electric method to the investigation of metallic ore deposit, both field data simulation and inversion are carried out for several simplified ore deposit models. Our interest is in a vein-type model, because most of the ore deposits (more than 70%) exist in a vein type in Korea. Based on the fact that the width of the vein-type ore deposits ranges from tens of centimeters to 2m, we change the width and the material property of the vein, and we use 40m-electrode spacing for our test. For the vein-type model with too small width, the low resistivity zone is not detected, even though the resistivity of the vein amounts to 1/300 of that of the surrounding rock. Considering a wide electrode interval and cell size used in the inversion, it is natural that the size of the low resistivity zone is overestimated. We also perform field data simulation and inversion for a vein-type model with surrounding hydrothermal alteration zones, which is a typical structure in an epithermal ore deposits. In the model, the material properties are assumed on the basis of resistivity values directly observed in a mine originated from an epithermal ore deposits. From this simulation, we can also note that the high resistivity value of the vein does not affect the results when the width of the vein is narrow. This indicates that our main target should be surrounding hydrothermal alteration zones rather than veins in field survey. From these results, we can summarize that when the vein is placed at the deep part and the difference of resistivity values between the vein and the surrounding rock is not large enough, we cannot detect low resistivity zone and interpret the subsurface structures incorrectly using the electric method performed at the surface. Although this work is a little simple, it can be used as references for field survey design and field data Interpretation. If we perform field data simulation and inversion for a number of models and provide some references, they will be helpful in real field survey and interpretation.

Development and Performance Evaluation of an Animal SPECT System Using Philips ARGUS Gamma Camera and Pinhole Collimator (Philips ARGUS 감마카메라와 바늘구멍조준기를 이용한 소동물 SPECT 시스템의 개발 및 성능 평가)

  • Kim, Joong-Hyun;Lee, Jae-Sung;Kim, Jin-Su;Lee, Byeong-Il;Kim, Soo-Mee;Choung, In-Soon;Kim, Yu-Kyeong;Lee, Won-Woo;Kim, Sang-Eun;Chung, June-Key;Lee, Myung-Chul;Lee, Dong-Soo
    • The Korean Journal of Nuclear Medicine
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    • v.39 no.6
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    • pp.445-455
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    • 2005
  • Purpose: We developed an animal SPECT system using clinical Philips ARGUS scintillation camera and pinhole collimator with specially manufactured small apertures. In this study, we evaluated the physical characteristics of this system and biological feasibility for animal experiments. Materials and Methods: Rotating station for small animals using a step motor and operating software were developed. Pinhole inserts with small apertures (diameter of 0.5, 1.0, and 2.0 mm) were manufactured and physical parameters including planar spatial resolution and sensitivity and reconstructed resolution were measured for some apertures. In order to measure the size of the usable field of view according to the distance from the focal point, manufactured multiple line sources separated with the same distance were scanned and numbers of lines within the field of view were counted. Using a Tc-99m line source with 0.5 mm diameter and 12 mm length placed in the exact center of field of view, planar spatial resolution according to the distance was measured. Calibration factor to obtain FWHM values in 'mm' unit was calculated from the planar image of two separated line sources. Te-99m point source with i mm diameter was used for the measurement of system sensitivity. In addition, SPECT data of micro phantom with cold and hot line inserts and rat brain after intravenous injection of [I-123]FP-CIT were acquired and reconstructed using filtered back protection reconstruction algorithm for pinhole collimator. Results: Size of usable field of view was proportional to the distance from the focal point and their relationship could be fitted into a linear equation (y=1.4x+0.5, x: distance). System sensitivity and planar spatial resolution at 3 cm measured using 1.0 mm aperture was 71 cps/MBq and 1.24 mm, respectively. In the SPECT image of rat brain with [I-123]FP-CIT acquired using 1.0 mm aperture, the distribution of dopamine transporter in the striatum was well identified in each hemisphere. Conclusion: We verified that this new animal SPECT system with the Phlilps ARGUS scanner and small apertures had sufficient performance for small animal imaging.