• 한국미생물·생명공학회지
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• 제46권4호
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• pp.430-433
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• 2018

Hepatitis B is a major health problem in China. However, little is known about the prevalence of hepatitis B virus (HBV) in Kaifeng, the major urban capital of Henan province, China. We found that HBV prevalence increased with age and that chronic HBV was predominant in adult males in Kaifeng. The HBV prevalence remained unchanged over a 5-year period for all age groups. Alarmingly, 25% of the population remained unvaccinated and potentially susceptible to future HBV infection. HBV immunization and health education initiatives should be carried out in this population to further reduce the overall prevalence of HBV.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.685-689
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• 2013

Objective: To study the effects of down-regulation of HDAC6 expression on proliferation, cell cycling and migration of esophageal squamous cell carcinoma (ESCC) cells and related molecular mechanisms. Methods: ESCC cell line EC9706 cells were randomly divided into untreated (with no transfection), control siRNA (transfected with control siRNA) and HDAC6 siRNA (transfected with HDAC6 small interfering RNA) groups. Effects of HDAC6 siRNA interference on expression of HDAC6 mRNA and protein in EC9706 cells were investigated by semi-quantitative RT-PCR, Western blotting and immunocytochemistry methods. Effects of down-regulation of HDAC6 expression on cell proliferation, cell cycle, and cell migration were studied using a CCK-8 kit, flow cytometry and Boyden chambers, respectively. Changes of mRNA and protein expression levels of cell cycle related factor (p21) and cell migration related factor (E-cadherin) were investigated by semi-quantitative RT-PCR and Western blotting methods. Results: After transfection of HDAC6 siRNA, the expression of HDAC6 mRNA and protein in EC9706 cells was significantly downregulated. In the HDAC6 siRNA group, cell proliferation was markedly inhibited, the percentage of cells in G0/G1 phase evidently increased and the percentage of cells in S phase decreased, and the number of migrating cells significantly and obviously decreased. The mRNA and protein expression levels of p21 and E-cadherin in the HDAC6 siRNA group were significantly higher than those in the untreated group and the control siRNA group, respectively. Conclusions: HDAC6 siRNA can effectively downregulate the expression of HDAC6 mRNA and protein in EC9706 cells. Down-regulation of HDAC6 expression can obviously inhibit cell proliferation, arrest cell cycling in the G0/G1 phase and reduce cell migration. The latter two functions may be closely related with the elevation of mRNA and protein expression of p21 and E-cadherin.

• Journal of the Korean Institute of Landscape Architecture International Edition
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• 제1호
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• pp.202-207
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• 2001

Covering an area of about 39 ha, Qingming Shanghe Park is located in the northwest of Kaifeng, formerly the capital of seven dynasties in China. It is intended to serve as a tourist attraction based on a painting 〃Qingming Festival at Riverside〃 by Zhang Zeduan of the Northern song Dynasty, which vividly illustrates a real life on the both sides of the Bian River as well as in the urban area, Kaifeng, in early Spring. The park is a collection of varied buildings such as shops, restaurants, tea-houses, theaters, and hotels in the North song style, with an introduction of the history of Kaifeng, this paper examines design philosophy and methodology of the park, and discusses the creative design of the first stage development known as known as The South Area of the park. Marked by the Rainbow Bridge and the City Gate, the South Area is divided into three parts, the rural, suburban, and urban parts which are organized according to the spatial order showed in the painting. The South Area proves to be very successful because of its amazing sense of history and interesting folk performance. Furthermore, the preliminary 9planning of the second stage development known as The North Area is presented with references to culture, history and customs. The North Area is proposed to include the Old Sports & Games Garden, the Exhibition Garden, and the Hot Spring Garden with an appearance of the imperial gardens in the Northern Song, integrated with participation of old sports and games, display of old science & technology achievements, and enjoyment of hot spring bath.

• Korean Journal of Chemical Engineering
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• 제35권11호
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• pp.2296-2302
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• 2018

Internally plasticized PVC was prepared via chemical reaction of azide PVC and alkynyl group containing castor oil methyl ester. The chemical structure of alkynyl group containing castor oil methyl ester and internally plasticized PVC was characterized with FT-IR and $^1H$ NMR. Properties of internally plasticized PVC, including thermal stability, tensile tests and resistance to extraction in different solvents, was investigated. The results showed that alkynyl group containing castor oil methyl ester, as internal plasticizer of PVC, not only decreased the $T_g$ of PVC from $84.6^{\circ}C$ to $41.6^{\circ}C$ efficiently, but also presented no plasticizer loss in five different solvents. The tensile tests showed that elongation at break and tensile strength of internally plasticized PVC was 353.8% and 18.1 MPa. The internally plasticized PVC has potential application in replacing the traditional PVC material in PVC products with high durability.

• 한국의사학회지
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• 제34권1호
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• pp.59-74
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• 2021

Li Gao left a great mark in the history of Chinese medicine by founding Piwei (脾胃) theory. When explaining Li Gao's medical ideology, researchers explain that his medical ideology was created by curing hunger during wartime and treating diseases of people who suffered from battle field trauma. However, Li Gao also suffered from battlefield trauma for his experience of the Mongol siege of Kaifeng (開封城) from 1232 to 1233. It is the hypothesis of this study that Li Gao himself would have suffered posttraumatic stress disorder (PTSD), and this study reexamines the process more closely from the viewpoint of PTSD and posttraumatic growth (PTG). The conclusion of this study is that his achievement in medical history is a result of his PTG. Li Gao's narrative of Piwei (脾胃) theory contains elements that seek revenge against the Mongol soldiers, and Li Gao achieved extraordinary PTG by overcoming the trauma of the siege of Kaifeng step by step.

• 한국콘텐츠학회논문지
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• 제21권3호
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• pp.143-156
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• 2021

본 연구에서는 카이펑 시 역사 문화거리인 서점거리를 대상으로 서점거리의 경관 구성 요소에 나타난 경관 색채의 특징을 분석하여 서점거en리의 환경 색채에 대한 전체성을 이론적 배경을 제공하고자 한다. 문헌 고찰을 통해 역사 문화거리의 경관 구성요소에 대한 체크리스트를 도출하고, 청대 건축적 색채의 일반적인 특징과 경관 색채의 기본적인 분석방법에 대해 파악하였다. 또한, 서점거리 경관 구성의 요소 및 경관 색채에 대한 현장조사를 실시하고 색채 분석은 <한국표준색 색채분석> 프로그램을 적용하여 분석을 진행하였으며, 색상수치 표기는 먼셀 표색계를 사용하여 표기하였다. 연구 결과를 보게 되면 서점거리의 경관색채는 R계열, PB계열, Y계열, 무채색(N)계열로 구성되어 있으며 전체적으로 색채는 높은 전체성을 나타내었다. 청대 건축 색채의 일반적인 특성을 비교함으로써 서점거리의 전체적인 경관 색채는 청대 건축 색채의 일반적인 특성에 상당 부분 부합한다는 것을 알 수 있었다. 그러나 사인과 시설물, 조형물의 색채 활용에서는 미흡한 부분이 많이 존재하였기에 사인과 시설물 등 경관 요소의 색채계획을 추가하여 시각 정보의 식별 가능성을 강화하고 거리 색채의 단계적인 변화를 증가시켜야 할 필요성이 요구된다.

• 헤리티지:역사와 과학
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• 제45권3호
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• pp.114-159
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• 2012

송대는 정치 경제 그리고 문화를 통틀어 중국 역사상의 중요한 전환기이며, 정치제도와 경제체제, 사상의식과 문화특징 등 모든 면에서 중요한 변혁이 있었다. 이러한 변화는 대부분 당대(唐代) 후기에 시작되어 북송시기에 완성되었다. 물론 그 발전이 비교적 긴 과정을 거쳤지만, 그 변화는 거대하고도 본질적인 것이었다. 때문에 각 분야의 제도에 비교적 강력하게 나타났으며, 그 가운데 도성의 조직체계와 특징에서 더욱 뚜렷하게 드러난다. 송대 정치제도 변화의 핵심은 동한(東漢) 이래 형성된 사족문벌제도(士族門閥制度)가 철저하게 붕괴되고 황제를 중심으로 긴밀하고 완벽한 관료체제가 형성되었다는 것으로, 송대는 고도로 집중된 중앙집권체제를 이루었다. 이는 대략 재상(宰相)집단의 형성, 중앙정권의 권력분화, 황제의 지방통제 강화, 관리선출과 과거제도의 개선 등의 내용을 포괄한다. 이로부터 황제는 전 분야에 뻗치는 막강한 권력을 쥐게 되었으며, 각종 제도의 제정은 황제의 권력과 지위 강화라는 목적으로 직결되지 않는 것이 없었다. 동시에 송대는 경제가 고도로 발전한 시기로, 농촌에서는 조전제(租田制)를 핵심으로 하는 생산구조가 형성되어 농업발전이 극대화되었고, 만당(晩唐) 시기부터 농업과 수공업 기술의 발전에 힘입어 상품경제의 발전이 가속화되기 시작하여, 송대에 이르러서는 상업의 사회경제적 위상이 크게 향상되고 나아가 도시경제체계를 형성하게 되었다. 정치제도의 변화와 경제적 발전이 각종 도시제도의 형성에 영향을 미친 것이다. 이 글에서는 1980년대 초기 이후로 북송 동경 변량성(東京 지금의 河南省 開封市)에 대해 진행된 고고학적 작업을 정리하고, 또한 그 성과에 근거하여 북송 동경 변량성의 특징을 간략하게 종합해 보고자 한다.

• Journal of Information Processing Systems
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• 제17권2호
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• pp.385-398
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• 2021

The complexity of deep learning models affects the real-time performance of gesture recognition, thereby limiting the application of gesture recognition algorithms in actual scenarios. Hence, a residual learning neural network based on a deep convolutional neural network is proposed. First, small convolution kernels are used to extract the local details of gesture images. Subsequently, a shallow residual structure is built to share weights, thereby avoiding gradient disappearance or gradient explosion as the network layer deepens; consequently, the difficulty of model optimisation is simplified. Additional convolutional neural networks are used to accelerate the refinement of deep abstract features based on the spatial importance of the gesture feature distribution. Finally, a fully connected cascade softmax classifier is used to complete the gesture recognition. Compared with the dense connection multiplexing feature information network, the proposed algorithm is optimised in feature multiplexing to avoid performance fluctuations caused by feature redundancy. Experimental results from the ISOGD gesture dataset and Gesture dataset prove that the proposed algorithm affords a fast convergence speed and high accuracy.

• Structural Engineering and Mechanics
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• 제89권6호
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• pp.571-578
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• 2024

The bistable thin cylindrical shell is developable structure with the ability to transition between its two stable configurations. This structure offers significant potential applications due to its excellent deformability. In this paper, the composite thin cylindrical shell consisting of the composite layer and the piezoelectric layer was investigated. The material and geometric parameters of the shell were found to influence its stable characteristics. The analysis model of the composite thin cylindrical shell incorporating the piezoelectric layer was developed, and the expressions for its strain energy were derived. By applying the minimum energy principle, the impact of the electric field intensity on the bi-stable behaviors of the cylindrical shell was analyzed. The results showed that the shell exhibited the bistability only under the appropriate electric field strength. And the accuracy of the theoretical prediction was verified by simulation experiments. This study provides an important reference for the application of deployable structures.

• Journal of Microbiology and Biotechnology
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• 제23권10호
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• pp.1460-1471
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• 2013

Microalgal biofuel production from wastewater has economic and environmental advantages. This article investigates the lipid production from high chemical oxygen demand (COD) bioethanol wastewater without dilution or additional nutrients, using a newly isolated heterotrophic microalga, Chlorella vulgaris LAM-Q. To enhance lipid accumulation, the combined effects of important operational parameters were studied via response surface methodology. The optimal conditions were found to be temperature of $22.8^{\circ}C$, initial pH of 6.7, and inoculum density of $1.2{\times}10^8cells/ml$. Under these conditions, the lipid productivity reached 195.96 mg/l/d, which was markedly higher than previously reported values in similar systems. According to the fatty acid composition, the obtained lipids were suitable feedstock for biodiesel production. Meanwhile, 61.40% of COD, 51.24% of total nitrogen, and 58.76% of total phosphorus were removed from the bioethanol wastewater during microalgal growth. In addition, 19.17% of the energy contained in the wastewater was transferred to the microalgal biomass in the fermentation process. These findings suggest that C. vulgaris LAM-Q can efficiently produce lipids from high-concentration bioethanol wastewater, and simultaneously performs wastewater treatment.