• 대한의료기공학회지
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• 제6권1호
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• pp.150-180
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• 2002

• 한국식품과학회지
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• 제33권3호
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• pp.333-337
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• 2001

오미자차 또는 음료 가공을 위한 오미자 볶음공정의 영향을 조사하기 위하여 볶음온도와 시간을 달리한 오미자 추출액의 이화학적 특성 및 관능 특성을 비교하고 볶음공정 변수가 관능특성에 미치는 영향을 반응표면기법으로 분석하여 볶음공정을 최적화 하였다. 온화한 볶음조건에서는 추출액의 산도, 고형분, 환원당 함량이 증가하였으나 과도한 볶음조건에서는 이들 함량이 감소하였다. 오미자 추출액의 색도는 볶음시간이 길어짐에 따라 추출액의 L값이 높아지는 경향을 보였으며 a값은 온도에 따라 높아졌다가 낮아지는 경향을 보였다. b값은 볶음에 의해 급격히 증가하는 경향을 보이다가 과도한 볶음 시 다시 감소하는 추세를 나타내었다. 오미자 추출액의 색깔에 대한 관능적 품질특성은 $180^{\circ}C$, 10분의 경우가 가장 높은 점수를 보였으며 반응표면으로 나타낸 결과 볶음에 의해 색깔이 전반적으로 향상되는 것으로 나타났다. 추출액의 향도 볶음에 의해 개선되었으며 $180^{\circ}C$, 10분 이상에서는 비슷한 점수를 보였다. 맛에 대한 반응표면은 $180^{\circ}C$에서 10분간 볶은 오미자로부터 추출한 경우가 가장 높은 점수를 보였다. 오미자 추출액의 종합적 기호도 역시 볶음에 의해 향상되었으며 온도 $180^{\circ}C$에서 10분간 볶은 오미자로부터 추출한 추출액이 가장 높은 점수를 보임으로써 오미자 볶음의 적정 조건은 $180^{\circ}C$, 10분으로 결정되었다. 오미자 추출액의 관능특성은 볶음에 의해 현저하게 향상되었다.

• 공업화학
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• 제26권2호
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• pp.159-164
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• 2015

Benzimidazolone계 황색 안료 Benzimidazolone 180 (P.Y. 180)은 잉크, 도료, 플라스틱, 토너, 칼라필터 등의 다양한 분야에서 널리 사용되며, 녹색 빛을 나타내는 황색 안료로 내열성, 내용제성 및 내산 염기성에 우수한 고기능성 안료이다. 본 연구에서는 커플링 반응을 통하여 다양한 온도 조건 하에서 합성하였으며 가압 장치 autoclave를 사용하여 여러 용매 및 온도별 결정화 처리를 통하여 시료의 물성에 미치는 영향을 고찰하였다. DMSO 용매를 사용하여 결정화 처리한 안료는 상대적으로 높은 회절 강도 비와 입자크기 증가, 분산성 향상, 색력 증가를 나타내었다.

• 한국축산식품학회지
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• 제36권1호
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• pp.77-83
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• 2016

This study aimed to investigate the anti-obesity effects of yogurt fermented by Lactobacillus plantarum Q180 in diet-induced obese rats. To examine the effects, male Sprague-Dawley rats were fed on six different diets, as follows: Group A was fed an ND and orally administrated saline solution; Group B, an HFD and orally administrated saline solution; Group C, an HFD and orally administrated yogurt fermented by ABT-3 and L. plantarum Q180; Group D, an HFD and orally administrated yogurt with added Garcinia cambogia extract, fermented by ABT-3 and L. plantarum Q180; Group E, an HFD and orally administrated yogurt fermented by L. plantarum Q180; and Group F, an HFD and orally administrated yogurt with added Garcinia cambogia extract, fermented by L. plantarum Q180 for eight weeks. After eight weeks, the rate of increase in bodyweight was 5.14%, 6.5%, 3.35% and 10.81% lower in groups C, D, E and F, respectively, compared with group B; the epididymal fat weight of groups E and F was significantly lower than that of group B; and the level of triglyceride and leptin was significantly reduced in groups C, D, E and F compared to group B. In addition, the level of AST was reduced in group C compared to the other groups. To examine the effects of yogurt on the reduction of adipocyte size, the adipocyte sizes were measured. The number of large-size adipose tissue was less distributed in groups A, C, D, E and F than in group B.

• 대한기계학회논문집A
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• 제40권12호
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• pp.987-995
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• 2016

본 연구는 $ZrO_2$의 비커스 경도에 대한 쇼트 피닝 효과를 연구하였다. 쇼트의 크기는 ${\phi}180{\mu}m$와 ${\phi}300{\mu}m$를 사용하여 피닝하였다. 비커스경도는 압입하중 98 N과 294 N으로 측정하였다. 비커스 경도는 와이블 통계 해석을 수행하여, 볼 크기 및 압압 하중에 따르는 영향을 평가하였다. 척도 파라메터는 98 N 압입 하중 및 ${\phi}180{\mu}m$ 쇼트 볼에서 크게 나타났다. 형상 파라메터도 대체적으로 작은 쇼트 볼(180sp)이 크게 나타났다. 이것으로부터 SP처리에 의한 압축 잔류 응력은 $ZrO_2$의 기계적 성질의 향상에 좋은 방법이다.

• 한국작물학회:학술대회논문집
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• 한국작물학회 1998년도 춘계 학술대회지
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• pp.179-180
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• 1998

• 대한약침학회지
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• 제5권1호
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• pp.61-79
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• 2002

Objective: The purpose of this study was to investigate acute and subacute toxicity and sarcoma-180 anti-cancer effects of Herbal acupuncture with Anneniacae amarum semen (Haeng-in) in mice and rats. Method: Balble mice were injected intraperitoneany with Haeng-In extract for $LD_{50}$ and acute toxicity test. Sprague-Dawley rats were injected intraperitoneally with Haeng-In extract for subacute toxicity test. TheAnneniacae amarum semen Herbal-Acupuncture was injected on Chung-wan (CV12) of mice with Sarcoma-180 cancer cell line. Results: 1. $LD_{50}$ was uncountable as none of the subjects expired from the treatment groups during the test. 2. The clinical signs and the body weight of mice treated with 0.1cc and 0.2cc Haeng-In extract were not affected during the acute toxicity test. 3. In acute toxicity test of serum biochemical values of mice, total protein and albumin were decreased in treatment group Ⅰ. Glucose was increased, and total cholesterol was decreased in treatment groups. GPT was increased in treatment group Ⅰ. 4. In subacute toxicity test, toxic symptoms were not detected in the treatment groups. 5. In subacute toxicity test, the body weight was increased in treatment groups on 14th and 21st day. 6. In subacute toxicity test. liver weight was increased in treatment group Ⅱ, and spleen weight was increased in treatment group Ⅱ. Lung weight was increased in an the treatment groups.(p<0.05) 7. In subacute toxicity test, severe tissue injury was found in lung and liver, especially treatment group Ⅰshowed more significant lung damage compared to treatment group l. 8. In subacute toxicity test, WBC. MCH and MCHC were increased in an the treatment groups, RBC, HGB and HCT were decreased in treatment group H(p<0.05). 9. In subacute toxicity test of serum biochemical values of rats, triglyceride was decreased in all the treatment groups. ALP was decreased in treatment group Ⅰ. and creatinine was decreased in treatment group Ⅱ. BUN/CR was increased in treatment group Ⅱ(p<0.05). 10. Median survival time of Sarcoma-180 cancer cell treated with Haeng-In was increased in all the treatment groups by twenty percent, compared to the control group(p<0.05). 11. Natural killer cell activity about the Sarcoma-180 cell was decreased at the ratio of 100:1 but was increased at the ratio of 10:1. In treatment group Ⅱ, increase was found at the ratio of 100:1 and 50:1 (p<0.05). 12. Interleukin-2 productivity of the Sarcoma-180 cell was decreased in treatment group I, but was increased in treatment group Ⅱ(p<0.05). Conclusion: According to the results, we can conclude Herbal-acupuncture with Anneniacae amarum semen caused toxicity, and had effects in Sarcoma-180 cancer cell.

• 설비공학논문집
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• 제17권7호
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• pp.635-641
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• 2005

This study experimented to understand the effects of transporting ice slurry through elbow and inclined tube. And at this experiment it used propylene glycol-water solution and a diameter of about 2mm ice particle. The experiments were carried out under various conditions, with velocity of water solution at the entry ranging from 1.0 to 3.5 w/s and elbows and inclined tubes of 4 kinds angle with $30^{\circ},\;45^{\circ},\;90^{\circ}\;and\;180^{\circ}$. The pressure drop between the tube entry and exit were measured. According to angle of bending, the highest pressure drop was measured at $30^{\circ}$ elbow and the lowest pressure drop was measured at $90^{\circ}$ elbow, and there are only a little differences of pressure drop between $45^{\circ}$ elbow and $180^{\circ}$ elbow. According to angle of inclined tube, the highest pressure drop was measured at $90^{\circ}$ inclined tube and the pressure drop at $45^{\circ},\;30^{\circ},\;180^{\circ}$ inclined tubes were lower successively. The lowest pressure drop in elbows and inclined tubes was measured at velocity of $2.0\~2.5$ m/s and concentration of $10\;wt\%$.

• 생약학회지
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• 제22권4호
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• pp.233-239
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• 1991

Phellinus linteus was examined for its anticancer activity using an animal model. Water extract of Phellinus linteus was prepared from artificially cultivated mycelia. Neither toxicity nor abnormal changes of hematological parameters were observed in the rat given orally with high doses of drug extract for 15 days. ICR mice were transplanted with Sarcoma-180 tumor cells intraperitoneally and drug extract was daily given to the mice from 1 day after tumer transplantation for 3 weeks. Administration of drug extract significantly prolonged the survival duration of Sarcoma 180-transplanted mice. For the better understanding of the anticancer activity, we have examined the effect of the drug extract administration on various killer cell functions, such as natural killer(NK) cells, cytotoxic T-lymphocytes (CTL) and macrophages which have been known to be main effector cells in immune responses against tumors. The results from the 4 hr $^{51}Cr-release$ assay have shown that the drug extract augments mouse NK cell activity but neither CTL nor macrophages. It is possible, then, that the anticancer activity of the Phellinus linteus may be associated with augmentation of NK cell function in the cancerated hosts.

• Journal of Acupuncture Research
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• 제22권2호
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• pp.203-210
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• 2005

Objectives : The purpose of this study was to investigate anti-cancer effects of various ginseng herbal acupuncture in mice and expression of cytokine mRNA. Methods: Anti-cancer effects of various ginseng herbal acupuncture were tested by measuring the increase of life span of mice suffering from peritoneal cancer induced by Sarcoma-180, and expression of mRNA manifestation using RT-PCR. The results are as follows: Results: 1. Increase of life span of mice suffering from peritoneal cancer induced by Sarcoma-180 was measured for anti-cancer effects. As a result, 115% increase was shown in the cultivated wild ginseng group, 11.1% increase in the red ginseng group, and no increase was detected in either white ginseng and fresh ginseng groups. 2. Measuring the expression of cytokine mRNA manifestation, expression of $interferon-{\gamma}$ was slightly increased in the cultivated wild ginseng group compared to the control group, but manifestation of interleukin-10 was slightly decreased. 3. For the red ginseng, white ginseng, and fresh ginseng experiment groups II, IL-2, IL-4, $INF-{\gamma}$, and IL -10 all showed increase suggesting possible error occurring during the test process. Conclusion: From the results obtained in this study, we can reason that the ginseng we use may not match the ginseng cited in the texts of the past. Anti-cancer effects of cultivated wild ginseng can be more potent than those of white and fresh ginseng.