• Journal of Veterinary Clinics
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• v.18 no.4
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• pp.424-428
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• 2001

Keratoconjunctivitis sicca (KCS) is a relatively common eye disease in the dog, Reduction or arrest of aqueous tear production by lacrimal glands results in quantitative alteration of the precorneal tear film (PTF) and KCS may result. A dog with a presumptive diagnosis of KCS referred was used for the study of KCS. Cytological and histopathologic examination is performed, and the various types of medical and surgical treatment are studied, including the operation of parotid duct transposition (PDT). This report described unilateral KCS in a dog of unknown etiology who responded to PDT.

• Journal of Veterinary Clinics
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• v.19 no.2
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• pp.260-263
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• 2002

Twenty-nine dogs with chronic keratoconjunctivitis sicca (KCS) were treated by topical administration of a petrolatum based 2% cyclosporine ointment twice daily. Causes and durations of KCS varied. Tear production increased in 25 of 32 eyes and clinical improvement in corneal health was noticed in 35 of 47 eyes. No serious adverse reactions were observed and only mild irritation was noticed by the owners immediately after the application of the ointment in some cases .

• Journal of Veterinary Clinics
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• v.22 no.3
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• pp.278-280
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• 2005

A four-year-old intact female poodle was referred with a history of ocular discharge and corneal ulcer to Veterinary Medical Teaching Hospital of Seoul National University. The dog was diagnosed severe keratoconjunctivitis sicca (dry eye) on bilateral eye. As the dog was not response to the ophthalmic medication, acupuncture treatment was applied to the dog. After 2 months from treatment, the dog was completely recovered from keratoconjunctivitis sicca. It is suggested that traditional veterinary medicine might be effective alternative therapy for the patient with keratoconjunctivitis sicca.

• Journal of the korean veterinary medical association
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• v.41 no.5
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• pp.413-420
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• 2005

• Journal of Veterinary Science
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• v.24 no.2
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• pp.32.1-32.10
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• 2023

Background: The association between vitamin D and canine keratoconjunctivitis sicca (KCS) has not been investigated in dogs. Objectives: To investigate the association of serum 25-hydroxyvitamin D [25(OH)D] concentrations with Schirmer tear test 1 (STT-1) and tear film breakup time (TFBUT) in dogs. Methods: Sixty-one clinically healthy, client-owned dogs were enrolled. STT-1 and TFBUT were measured in 122 (61dogs) and 82 (41 dogs out of total 61 dogs) eyes, respectively. Serum 25(OH)D concentrations were evaluated by quantitative chemiluminescent immunoassay. The dogs were classified into 6 groups according to the evaluations (STT-1: group 1, normal [≥ 15 mm/min] in both eyes; group 2, normal in one eye and abnormal [< 15 mm/min] in the fellow eye; group 3, abnormal in both eyes; TFBUT: group 4, normal [≥ 20 sec] in both eyes; group 5, normal in one eye and abnormal [< 20 sec] in the fellow eye; group 6, abnormal in both eyes). Results: STT-1 was positively correlated with TFBUT (p < 0.001). Among the STT-1 groups, the mean serum 25(OH)D concentration in group 1 was significantly higher than in groups 2 and 3 with positive correlation (p < 0.001). However, there were no significant differences among the TFBUT groups 4, 5, and 6. Conclusions: In dogs, it was found that serum 25(OH)D concentrations had a greater effect on quantitative KCS than qualitative KCS. Therefore, it is considered that measurement of serum 25(OH)D concentration could be included in the diagnostic tests in canine quantitative KCS patients.

• Journal of Veterinary Clinics
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• v.32 no.4
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• pp.356-358
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• 2015

When severely large corneal perforation occurs, penetrating keratoplasty is a treatment of choice alternative to enucleation. A twelve-year-old male Shih Tzu was referred with perforated corneal ulcer secondary to keratoconjunctivitis sicca (KCS). Perforated cornea was directly sutured using 10-0 non-absorbable suture material, and rotational conjunctival flap was performed. However, re-perforation of cornea by wound dehiscence was observed at 1 month after operation. The yellowish lens escaped outside the orbit during corneal re-perforation, the diagnosis was re-perforated corneal ulcer, moderate corneal edema, moderate KCS (STT; 6 mm) and endophthalmitis caused by escaped lens outside orbit. Accordingly, penetrating keratoplasty (PK) and evisceration through corneal recipient site and intrascleral silicone ball prosthesis were carried out as the planned treatment, and resulted in good cosmetic improvement compared to enucliation. However, exposure of silicone ball occurred at the 9 months after the surgery due to the irritation of implant, thus enucleation was performed. In perforated large corneal ulcer with severe intraocular damage, evisceration with silicone ball insertion with PK would be alternative treatment choice to improve the cosmetic appearance.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.22 no.3
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• pp.188-195
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• 2009

Objective : The object of this literatual study is to investigate the etiology of dry eye syndrome Methods : We have selected data related to etiology of dry eye syndrome on the literature of Oriental Medicine. And we analyzed the study. Results : Treatment and etiology concerning dry eye syndrome derived diverse opinion according to medical era and practitioner. It was a good opportunity to speculate the etiology and similar symptoms of dry eye syndrome. Conclusions : Through literatual Study, we basically understood the etiology of dry eye syndrome. In the study of the etiology, it seems that further clinical studies on treatment of dry eye syndrome via oriental medicine.