• Title/Summary/Keyword: KCI

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Stability of Spheroplasts from Saccharomyces cerevisiae D-71 and Zygosaccharomyces rouxii SR-S (Saccharomyces cerevisiae D-71과 Zygosaccharomyces rouxii SR-S로부터 조제한 원형질체의 안정성)

  • 정창기;김찬조;이종수
    • Microbiology and Biotechnology Letters
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    • v.16 no.4
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    • pp.293-296
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    • 1988
  • Stability of spheroplasts prepared from Saccharomyces cerevisiae D-71, a thermophilic strain and Zygosaccharomyces rouxii SR-S, an osmotolerant strain were studied. Stability of spheroplast from Saccharomyces cerevisiae D-71 was highest in 0.8M KCI and 1.0M sorbitol ; that from Zygosaccharomyces rouxii SR-S was highest in 0.4M KCI and mannitol and that from both strains was less than 10% for sonic oscillation at 20Kc for 60 sec. In centrifugation at 10000 x g for 10 min., stability of spheroplast from Saccharomyces cerevisiae D-71 was 93% and that from Zygosaccharomyces rouxii SR-S was 84%. Breakage of spheroplast from Saccharomyces cerevisiae D-71 was 99% and that from Zygosaccharomyces rouxii SR-S was 55% for UV irradiation with 15W UV lamp at a distance of 20 cm for 60 min.

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Studies on the Effect and Mechanism of Geupoongjibo-dan's Relaxation on a Blood Vessel (거풍지보단(祛風至寶丹)의 혈관이완 효능과 기전에 관한 연구)

  • Kim, Dong-Eun;Park, Dong-Wan;Jeong, Sung-Hyun;Shin, Gil-Cho;Lee, Won-Chul;Han, Sung-Ho
    • The Journal of Internal Korean Medicine
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    • v.22 no.2
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    • pp.119-125
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    • 2001
  • Objectives : This study was conducted to evaluate the effect and mechanism of Geupoongjibo-dan's relaxation of the tension of the blood vessel caused by Phenylephrine and KCI. Methods : In order to study the effect of Geupoongjibo-dan's relaxation of the blood vessel tension, Geupoongjibo-dan extract was infused into Phenylephrine and KCI-induced contracted rabbit aorta strips. To analyze the mechanism of Geupoongjibo-dan's effect on the blood vessel, Geupoongjibo-dan extract infused into Phenylephrine and KCI-induced contracted strips induced by agonists after treatment of N${\omega}$-nitro-L-arginine, Methylene Blue. Results : 1. Geupoongjibo-dan was very effective in relaxing the blood vessels contracted by Phenylephrine. 2. Geupoongjibo-dan was effective against Phenylephrine, than against KCI. 3. Geupoongjibo-dan's more relaxation effect on a blood vessel was terminated by N${\omega}$-nitro-L-arginine and methylene treatment. Conclusion : THis study showed that Geupoongjibo-dan's relaxation effect on a blood vessel is irrelevant to ${\alpha}$-adrenalin receptor, and it relaxes contracted vessels through cGMP channel.

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A Study on the Trend of papers published by Korean Association of Information Education (한국정보교육학회 게재 논문들의 추세적 변화에 대한 고찰)

  • Moon, Wae-shik
    • Journal of The Korean Association of Information Education
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    • v.22 no.6
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    • pp.681-687
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    • 2018
  • Many papers are published in KCI-listed journals for objectively validating research results and evaluations. This study collected articles published from 2008 to October, 2018 (10 years) of KAIE, which is a representative KCI registration institute which publishes various research related to elementary information education, and classified and analyzed by 10 subject areas. As a result, 34.2% of the papers published in the topic related to software education were found in the whole papers, and 33% of the papers published in this society showed the highest number of citations of papers relating to software education. Many of the remaining articles analyzed by subject area were overlapped with software education in the field of small scale medicine. In the future, a considerable number of researchers are expected to focus on software education.

Network Analysis of the Intellectual Structure of Addiction Research in Social Sciences: Based on the KCI Articles Published in 2019 (사회과학 중독연구 분야의 지적구조에 관한 네트워크 분석 : 2019년도 KCI 등재 논문을 기반으로)

  • Lee, Serim;Chun, JongSerl
    • The Journal of the Korea Contents Association
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    • v.21 no.10
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    • pp.21-37
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    • 2021
  • This study investigated the intellectual structure of the latest trends in Korean addiction research in the social sciences. A network analysis of keywords with co-word occurrence was performed on 172 papers from the KCI database based on the data from the year of 2019, and a total of 432 keywords were extracted. The network analysis was performed using several programs: Bibexcel, COOC, WNET, and NodeXL. As a result of the study, keywords related to addiction type, study subjects, research methods, and research variables were found, and a total of 20 clusters were identified. Furthermore, to identify and measure weighted networks, the relationships between each keyword were explored and discussed in detail through a network analysis of global centralities, local centralities, and betweenness centralities. The study indicated that the latest issues were focused on smartphone addiction and provided implications for the future research and practice that fields and topics of relationship addiction, food addiction, and work addiction should be more considered. Further, the study discussed the relationship between drug addiction-crime, alcohol addiction-family, and gambling addiction-motivation and the necessity of qualitative study.

A Study on Major Issues of Artificial Intelligence Using Keyword Analysis of Papers: Focusing on KCI Journals in the Field of Social Science (논문 키워드 분석을 통한 인공지능의 주요 이슈에 관한 고찰 : 사회과학 분야의 KCI 등재학술지를 중심으로)

  • Chung, Do-Bum;You, Hwasun;Mun, Hee Jin
    • The Journal of the Korea Contents Association
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    • v.22 no.7
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    • pp.1-9
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    • 2022
  • Today, artificial intelligence (AI) has emerged as a key driver of national competitiveness, but it is also causing unexpected side effects in society. This study intends to examine major social issues by collecting papers on AI targeting KCI journals in the field of social science. Therefore, we conducted keyword analysis of papers from 2016 to 2020. As a result of the analysis, the keywords for 'robot' and 'education' appeared the most, and the top six clusters (issues) were derived through the keyword network. The main issues are as follows: the background and/or basic concept of AI, AI education, side effects of AI, legal issues of AI-based creations, intention to use AI products/services, and AI ethics. The results of this study can be used to expand the discussion on the social aspects of AI and to find policy directions at the national level.

PRACTICAL USE OF KOREAN MEDICAL DATABASE (국내 의학 데이테베이스의 활용)

  • Lee, Hyo-Seol;Kim, Jong-Soo;Lee, Jae-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.39 no.3
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    • pp.325-331
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    • 2012
  • Korean medical databases are various from managing institutions. Korean major medical databases are KoreaMed, KoMCI, Synapse of Korean Association of Medical Journal Editors (KAMJE) made by medical researchers and doctors, and KMbase of Medical Research Information Center (MedRIC), RISS of Korea Education & Research Information Service (KERIS), NDSL of Korea Institute of Science and Technology Information (KISTI), KCI of National Research Foundation of Korea (NRF) made by government. Private companies made KISS (Koreanstudies Information Service System) and DBpia are providing medical information on charge. Internet portal site, Google and Naver, also provide enormous materials.

An Analysis on the Operations of Reference Databases in Korea (국내 참고문헌 데이터베이스 운영현황 및 실태에 관한 분석)

  • Kim, Hong-Ryul;Joung, Kyoung-Hee
    • Journal of the Korean Society for information Management
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    • v.22 no.2 s.56
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    • pp.23-39
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    • 2005
  • The purpose of this study was to analyzes the present conditions of reference databases which is constructed from Korea. The object which is used in analysis concludes on KSCI( Korean Science Citation Index) of KISTI, KCI(Korean Citation Index) of KRF, KoMCI(Korean Medical Citation Index) of Korean Academy of Medical Sciences, and reference database of KOSEF. And then, this paper proposes the activation plan for reference database construction based on this analysis result. The proposed plan will be able to apply with fundamental data of the system, policy and technical direction for reference database construction.

Studies on the Myofibrillar Proteins from Korean Native Goat (한국재래산양육(韓國在來山羊肉)의 근원섬유(筋原纖維) 단백질(蛋白質)에 관(關)한 연구(硏究))

  • Hong, Jong-Yong;Moon, Yoon-Hee;Koh, Jin-Bok
    • Journal of Nutrition and Health
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    • v.11 no.3
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    • pp.37-42
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    • 1978
  • Actomyosin and myofibril were extracted from Korean native Goat muscle with the Weber-Edsall solution. ATPase activities and physiochemical properties were measured. The results obtained were as follows; 1) Mg-activitied ATPase activity of actomyosin and myofibrill from Korean native Goat muscle exhibited a common biphasic response, a typical ATPase pattern, that is high at a low ionic strength and low at a high ionic strength. Actomyosin showed high activity than myofibrill. 2) Mg-activited ATPase activity of actomyosin from muscle increased extraction time 24 hours. 3) EDTA-enhanced ATPase activity of actomyosin was greater than myofibrill and low at the low ionic strength, high at the high ionic strength. The difference of the activity were shown great broad pattern at the after 0.3M KCI concentration. 4) Effect of EGTA on-ATPase activity of myofibrill and actomyosin from muscle was measured, the Mg-ATPase activity was markedly depressed. 5) Solubility of actomyosin from muscle began to solubilize at KCI concentration of 0.28M and solubilized completely at the KCI concentration of 0.3M.

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Immunosuppression Associated with Ovine Foetal Skin Extracts (면양태아피부추출액(緬羊胎兒皮膚抽出液)의 세포면역(細胞免疫) 기능저하(機能低下) 효과(效果)에 관(關)한 연구(硏究))

  • Jun, Moo Hyung
    • Korean Journal of Agricultural Science
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    • v.11 no.2
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    • pp.344-351
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    • 1984
  • Crude 3 M KCI extracts of ovine foetal skin (FLS) were shown to induce serum inhibition of lymphocyte blastogenesis when injected to normal sheep. When fractionated through Sephadex C-150 columns, four protein peaks were obtained, immunosuppressive activity in vitro and in vivo being associated with Peak IV. In discussion, the immunosuppressive activity of FLS is compared with that obtained with extracts of ovine squamous cell carcinoma, and possible identity of the immunosuppressors is suggested.

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Pharmacodynamics of Potassium Channel Opener Lemakalim in the Isolated Rat Hearts and Conscious SHRs under Hyperkalemic and Hypokalemic Condition (칼륨채널 활성물질 Lemakalim의 고칼륨혈증 및 저칼륨혈증에서의 심기능에 대한 영향 및 항 고혈압작용)

  • 신홍섭;신화섭;권광일
    • YAKHAK HOEJI
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    • v.37 no.5
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    • pp.463-475
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    • 1993
  • Pharmacological effects of lemakalim on cardiovascular system were investigated using isolated rat hearts and conscious SHRs subjected to hyperkalemic and hypokalemic condition. In the isolated hearts perfused with normal physiological salt solution(4.7 mM KCI), lemakalim increased cardiac function and coronary flow, and these effects were significantly potentiated under hypokalemic(1.2, 2.5 mM KCI), but attenuated under hyperkalemic(IO mM KCI) condition. In conscious SHRS, lemakalim(0.1, 0.2, 0.3mg/kg, p.o.) produced a dose-related decrease in systolic blood pressure, the maximal hypotensive effect being reached around 0.5 hr after dosing. The intensity and the duration of hypotensive effect of lemakalim were significantly increased when administered in combination with dihydrochlorothiazide (2 mg/kg, p.o.), but decreased with triamterene(32 mg/kg, p.o.). It appears that the differential effects of two types of diuretics on the hypotensive action of lemakalim are due to their hypokalemic and hyperkalemic action, respectively. It is conclued that the concomitant use of $K^{+}$ channel openers and hypokalemic diuretics may be an appropriate model of combination therapy in the treatment of hypertension.

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