• 한국멀티미디어학회논문지
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• 제15권9호
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• pp.1149-1155
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• 2012

본 논문에서는 반도체 산업 영상에서 반도체의 결함 원인 진단 기법을 제안한다. 제안 기법은 먼저 결함 영상에 대한 특징 데이터베이스를 구축한다. 다음으로 결함 영상과 입력 영상을 블록 단위로 영역 분할을 수행한 후 컬러 히스토그램을 계산하여 블록들 사이의 히스토그램 카이 제곱 거리를 이용한 블록 유사성을 측정한다. 다음으로 각 영상에서 탐색된 블록들에 대하여 클러스터링을 수행하여 영역을 연결된 객체 단위로 군집한다. 마지막으로 각 클러스터들의 특징을 추출하여 클러스터 간 유사성 측정으로 가장 유사성이 높은 결함 영상을 특징 DB에서 탐색하여 결함 원인 정보와 함께 제시한다. 검색 결과 유사도 상위 n개의 영상 중에서 입력 영상과 동일한 범주의 결함을 갖는 영상이 검색되는 비율을 구하여 제안 기법의 정확성을 검증하였다. n = 1, 2, 3에 대해서 결함 범주에 상관없이 검색 정확도는 모두 100%로 제안 기법은 실제 산업 응용이 가능한 정확한 검색 결과를 보여주었다.

• Journal of Microbiology and Biotechnology
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• 제27권11호
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• pp.2060-2069
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• 2017

Newcastle disease is a serious infectious disease in the poultry industry. The commercial vaccines can only offer limited protection and some of them are expensive and need adjuvants. At present, DNA vaccines are widely used. However, the immune responses induced by DNA vaccines are too slow and low. Here, we constructed the transfer vectors with a different number of C3d as molecular adjuvants (n = 1, 2, 4, or 6), and the vectors were cloned into the optimal eukaryotic expression plasmid (pVAXI-optiF) that expressed the F gene of Newcastle disease virus (NDV), and named pVAXI-F(o)-C3d1, pVAXI -F(o)-C3d2, pVAXI-F(o)-C3d4, and pVAXI-F(o)-C3d6, respectively. Cell transfection test indicated that pVAXI-F(o)-C3d6 showed the highest expression. In vivo immunization showed that the chickens immunized with pVAXI-F(o)-C3d6 intramuscularly induced better immune responses than the chickens immunized with the other plasmids. The protective efficacy of pVAXI-F(o)-C3d6 was 80% after challenge with the highly virulent NDV strain F48E9. The results in this study showed that C3d6 could be used as a molecular adjuvant to quickly induce an effective immune response to control NDV.

• 대한한방소아과학회지
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• 제13권1호
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• pp.63-138
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• 1999

From all possible chinese medical literatures, I studied the history of chinese pediatrics by dividing into Chunqiu Zhanguo, QinHan dynasties, LiangJin, SuiTang five dynasties, Song Dynasty, Jin and Yuan dynasties, Ming Qing dynasties. The conclusions are summarized as followings 1. The mentions related with pediatrics existed already in Yan ruins turtle shell letters, and 〈Yellow Emperor's classic of internal medicine> in Chunqiu Zhanguo time formed the system of medicine, established the theoretical foundation. 2. Chang Ji established the system of diagnosis and treatment based on overall analysis of symptoms and signs in , and later pediatricians commonly applied his prescriptions to the febrile diseases. 3. The period from LiangJin to SuiTang, Pediatrics was established as special department then in , Chao Yuanfang stated the etiology, pathogenesis, symptomatology of pediatric diseases. 4. In Song dynasty. pediatric 4 major, symptoms that had been mentioned from SuiTang dynasties, were clearly established, pediatrical special books were published, and written by Qian Yi who is considered as the founder of chinese pediatrics, established the foundation of pediatrical division formation in distinction from adult fields. 5. In Jin and Yuan dynasties, four eminent physicians established the actual relationship between the theories and practical applications and insisted various and creative theories based on the classical medicine, for example, the theory that fire and heat in the body was the main cause of diseases of Liu Wansu purgation theory of Zhang Congzheng, qi regulating theory of Liu Gao, ministerial fire theory and the theory that yang is ever in excess while Yin is ever deficient of Zhu Zhenheng, etc, and they applied those theories to pediatrical various sides. 6, In Ming Qing dynasties, pediatrical specialists and pediatrical publications had increased, eg, father and son Xue Kai Xue Ji, Wan Quan, Lu Bai-si, etc in Ming dynasty, Ye Gui, Chen Fuzheng, Xia Ding, etc in Qing dynasty were famous as pediatricians. Specially, the doctrine of epidemic febrile diseases at that time showed prominent effects to children's epidemic febrile diseases.

• 한국실내디자인학회논문집
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• 제23권1호
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• pp.88-95
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• 2014

This study intended arousal of other viewpoints that deal with and understand spaces and shapes, by describing the concept of 'dimensions' into visual patterns. Above all, the core concept of spatial dimensions was defined as 'expandability'. Then, first, the 'golden ratio', 'Fibonacci sequence', and 'fractal theory' were defined as elements of each dimension by stage. Second, a 'unit cell' of one dimension as 'minimum unit particles' was set. Next, Fibonacci sequence was set as an extended concept into two dimensions. Expansion into three dimensions was applied to the concept of 'self-similarity repetition' of 'Fractal'. In 'fractal dimension', the concept of 'regularity of irregularity' was set as a core attribute. Plus, Platonic solids were applied as a background concept of the setting of the 'unit cell' from the viewpoint of 'minimum unit particles'. Third, while 'characteristic patterns' which are shown in the courses of 'expansion' of each dimension were embodied for the visual expression forms of dimensions, expansion forms of dimensions are based on the premise of volume, directional nature, and concept of axes. Expressed shapes of each dimension are shown into visually diverse patterns and unexpected formative aspects, along with the expression of relative blank spaces originated from dualism. On the basis of these results, the 'unit cell' that is set as a concept of theoretical factor can be defined as a minimum factor of a basic algorism caused by other purpose. In here, by applying diverse pattern types, the fact that meaning spaces, shapes, and dimensions can be extracted was suggested.

• 대한화학회지
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• 제57권2호
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• pp.246-251
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• 2013

With -$OCH_2CO$- as a linker, a non ${\beta}$-substituted cationic bisporphyrin (4a) and a ${\beta}$-substituted cationic bisporphyrin (4b) were prepared through methylation of the intermediate which was obtained from ${\beta}$-amino-5,10,15,20-tetra (4-cyanophenyl) porphyrin or 5-hydroxylphenyl-10,15,20-tris(4-cyanophenyl) reacting with 5-hydroxy-10,15,20-trispyridinylporphyrin. Their structures were confirmed by $^1H$ NMR, IR, UV-vis, MS and elemental analysis. DNA photocleavage ability and the singlet oxygen ability of those cationic bisporphyrins were investigated. DNA photocleavage activity of ${\beta}$-substituted cationic bisporphyrin was significantly weaker than that of $H_2TMPyP$, but similar to that of non ${\beta}$-substituted cationic bisporphyrin. While 4a and 4b showed substantial photocleavage activities toward DNA, with 68% and 66% observed at 10 ${\mu}M$. The assessment of indirectly measured $^1O_2$ production rates against $H_2TMPyP$ were described and the relative singlet oxygen production yields were: free cationic bisporphyrins > $H_2TMPyP$. The results showed the cationic bisporphyrins with ${\beta}$-substitution and non ${\beta}$-substitution could be developed as potential photodynamic agents.

• 한국식물학회:학술대회논문집
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• 한국식물학회 1996년도 식물학심포지움 식물호르몬과 신호전달
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• pp.68-78
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• 1996

Two types of immunoloigcal probes, anti-ABBP Abs, have been developed. The purified ABBP from ABA-C1-BSA-sepharose 4B column was identified by PAGE and appeared in one band of about 56KD, as well as showed a specific binding ability and a high affinity for ABA (Kd2.0$\times$10-9 mol/L). Unexpectedly, the existence of rRNA with a length of around 300 nucleotides could be found, when the ABBP was digested with proteinase K and identified by eletrophorsis on an agarose gel (1%). As a result, about 120 cDNA clones coding maize 17s RNA and only one cDNA clone coding ABBP (24cDNA) were obtained from 200,000 seperated phage plaques by the anti-ABBP pAbs. 24cDNA had 1075bp and contained an open reading frame coding 254 amino acids. The anti-idiotypic Ab raised against an ABA MAb showed the ability of either mimicking ABA or competing with ABA. The localization of ABBPs in plant cell was investigated.

• Journal of Power Electronics
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• 제18권1호
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• pp.70-80
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• 2018

A novel strategy based on a zero common mode voltage pulse-width modulation (ZCMV-PWM) technique and zero-sequence circulating current (ZSCC) feedback control is proposed in this study to eliminate ZSCCs between three-level neutral point clamped (NPC) voltage source inverters, with common AC and DC buses, that are operating in parallel. First, an equivalent model of ZSCC in a three-phase three-level NPC inverter paralleled system is developed. Second, on the basis of the analysis of the excitation source of ZSCCs, i.e., the difference in common mode voltages (CMVs) between paralleled inverters, the ZCMV-PWM method is presented to reduce CMVs, and a simple electric circuit is adopted to control ZSCCs and neutral point potential. Finally, simulation and experiment are conducted to illustrate effectiveness of the proposed strategy. Results show that ZSCCs between paralleled inverters can be eliminated effectively under steady and dynamic states. Moreover, the proposed strategy exhibits the advantage of not requiring carrier synchronization. It can be utilized in inverters with different types of filter.

• International Journal of Industrial Entomology and Biomaterials
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• 제32권2호
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• pp.60-68
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• 2016

Pheromone orientation in moths is an exemplar of olfactory sensitivity. To avoid cross mating, the responses of males to pheromone blends must be high specificity and temporal resolution. We tested the effects of olfactory self- and cross-adaptation of pheromone compounds and mixtures in Spodoptera litura moths by electroantennogram (EAG) recordings. The challenge of S. litura antennae to a pulse train of its own pheromone blends of Z9,E11-14:OAc and Z9,E12-14:OAc with 200 ms on/off and 1 s on/off indicated that the repetitive stimulation by 200 ms on/off with high dosages resulted in greater adaptation than that by 1 s on/off with low dosages and the adaptation index of Z9,E11-14:OAc in all treatments is significantly larger than that of Z9,E12-14:OAc, suggesting that high dosages with more frequent stimulation prefer to induce sensory adaptations and a different odor coding exist between the two components in the antennal periphery in this moth. The cross-adaptation EAG test among the two pheromone compounds and Z7-12:OAc and Z9-14:OH from congeneric species of S. litura showed that each of these compounds adapted the antenna more to that specific compound. The significantly higher adaptation to Z7-12:OAc and Z9-14:OH than to the pheromone components of S. litura induced by themselves suggested that both of them are coded by specific odor receptor neurons which are different from those tuned to the pheromone components of S. litura . Thus, we proposed that Z7-12:OAc and Z9-14:OH may play an important role in avoidance of heterospecific mating between S. litura and its sympatric moth species.

• International Journal of Industrial Entomology and Biomaterials
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• 제33권2호
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• pp.149-149
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• 2016

Pheromone orientation in moths is an exemplar of olfactory sensitivity. To avoid cross mating, the responses of males to pheromone blends must be high specificity and temporal resolution. We tested the effects of olfactory self-and cross-adaptation of pheromone compounds and mixtures in Spodoptera litura moths by electroantennogram (EAG) recordings. The challenge of S. litura antennae to a pulse train of its own pheromone blends of Z9,E11-14:OAc and Z9,E12-14:OAc with 200 ms on/off and 1 s on/off indicated that the repetitive stimulation by 200 ms on/off with high dosages resulted in greater adaptation than that by 1 s on/off with low dosages and the adaptation index of Z9,E11-14:OAc in all treatments is significantly larger than that of Z9,E12-14:OAc, suggesting that high dosages with more frequent stimulation prefer to induce sensory adaptations and a different odor coding exist between the two components in the antennal periphery in this moth. The cross-adaptation EAG test among the two pheromone compounds and Z7-12:OAc and Z9-14:OH from congeneric species of S. litura showed that each of these compounds adapted the antenna more to that specific compound. The significantly higher adaptation to Z7-12:OAc and Z9-14:OH than to the pheromone components of S. litura induced by themselves suggested that both of them are coded by specific odor receptor neurons which are different from those tuned to the pheromone components of S. litura. Thus, we proposed that Z7-12:OAc and Z9-14:OH may play an important role in avoidance of heterospecific mating between S. litura and its sympatric moth species.

• Journal of Radiation Protection and Research
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• 제46권3호
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• pp.83-97
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• 2021

Background: The lifetime risk of lung cancer incidence due to radiation for nonsmokers is overestimated because of the use of the average cancer baseline risk among a mixed population, including smokers. In recent years, the generalized multiplicative (GM)-excess relative risk (ERR) model has been developed in the life span study of atomic bomb survivors to consider the joint effect of radiation and smoking. Based on this background, this paper discusses the issues of radiation risk assessment considering smoking in two parts. Materials and Methods: In Part 1, we proposed a simple method of estimating the baseline risk for nonsmokers using current smoking data. We performed sensitivity analysis on baseline risk estimation to discuss the birth cohort effects. In Part 2, we applied the GM-ERR model for Japanese smokers to calculate lifetime attributable risk (LAR). We also performed a sensitivity analysis using other ERR models (e.g., simple additive (SA)-ERR model). Results and Discussion: In Part 1, the lifetime baseline risk from mixed population including smokers to nonsmokers decreased by 54% (44%-60%) for males and 24% (18%-29%) for females. In Part 2, comparison of LAR between SA- and GM-ERR models showed that if the radiation dose was ≤200 mGy or less, the difference between these ERR models was within the standard deviation of LAR due to the uncertainty of smoking information. Conclusion: The use of mixed population for baseline risk assessment overestimates the risk for lung cancer due to low-dose radiation exposure in Japanese males.