• Elastomers and Composites
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• v.48 no.1
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• pp.18-23
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• 2013

Nylon 12 elastomer was slightly crosslinked in molten state by the addition of small amount of dicumyl peroxide (DCP) as a crosslink agent and triallycyanuate (TAC) as a co-agent during melt compounding at $160^{\circ}C$ in an internal mixer. The effect of the peroxide crosslinking on mechanical, dynamic mechanical and rheological properties of the nylon 12 elastomer was investigated by means of tensile testing, dynamic mechanical analysis (DMA) and small amplitude oscillating rheometer, respectively. With modification, there is an improvement in tensile modulus and Young's modulus with decease in elongation at break. DMA results for peroxide modified nylon 12 elastomers demonstrated that the glass transiaiton temperature of PTMG segment shifted to higher temperature and the storage modulus remained constant above the melting temperature of nylon 12 segments. Melt rheological studies revealed that the peroxide modified nylon 12 elastomer exhibited a more solid like behavior and stronger shear thinning behavior compared to neat nylon 12 elastomer, which was more prominent at higher TAC content in the polymer matrix. The peroxide modified nylon 12 elastomer exhibited good elastic recoverability and improved mechanical properties without sacrificing melt processibilty, and especially the service temperature range increased as compared to neat nylon 12 elastomer.

• Elastomers and Composites
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• v.55 no.1
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• pp.6-12
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• 2020

Poly(ethylene-co-vinyl acetate) compounds and vulcanizates containing dicumyl peroxide (DCP) (HD) were prepared, and the curing agent and reaction products were analyzed using gas chromatography/mass spectrometry (GC/MS). Samples containing trially cyanurate (TAC) and DCP (HDT) were also prepared and analyzed. Some raw DCP were decomposed in the injector region of GC to produce acetophenone. DCP was detected in the HD compound but was not observed in the HD vulcanizate, and instead acetophenone and 2-phenyl-2-propanol were detected. Both DCP and TAC were observed in the HDT compound but not in the HDT vulcanizate, where acetophenone and 2-phenyl-2-propanol were detected. Thus, some of the DCP decomposed during the compounding process. The formation mechanism for acetophenone and 2-phenyl-2-propanol during the crosslinking reaction was identified, and differences in the crosslinking reactions of HD and HDT compounds were discussed.

• Archives of Pharmacal Research
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• v.17 no.3
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• pp.194-198
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• 1994

The antitumor effects of the 2E4 and anti--Tac, monoclonal antibodies directed to Il-2 receptor (IL-2R) conjugated with .alpha.-particle emitting radionuclide bismuth-212., were compared. The $^{212}Bi-2E4$ demonstratedspecific cytotocicity to EL4J3, 4, a I$L-2R^+$ cell line, than to EL4J, a $IL-2R^-$ cell line in thymidine incorporation assy. TEX>$^{212}Bi-2E4$ exerted the maximal antitumor effect in that % T/C in C57BL/6 mice implanted with EL4J3.4 ascitic tumor was 331% at the concentration of $50{\;}{\mu}Ci$, while that of $^{212}Bi-anti-Tac$ was 258% at $100{\;}{\mu}Ci$.

• Clinical and Experimental Pediatrics
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• v.48 no.5
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• pp.476-480
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• 2005

Immunosuppressive therapy in pediatric renal transplant recipients is changing consequence of the increasing number of available immunosuppressive agents. The optimal use of immunosuppressive agents requires a thorough understanding of the pharmacokinetic characteristics, but the information on the pharmacokinetic characteristics of these drugs in pediatric transplant recipients is still limited. In general, patients younger than 5 years old show higher clearance rates, therefore the need for higher dosages in younger patients seems evident. By the therapeutic drug monitoring, trough($C_{min}$) and peak level($C_{max}$) are measured and the area under the blood concentration-time curve(AUC), which is taken as being representative of total systemic exposure can be calculated. Cyclosporine A (CSA) has poor bioavailability, which contributes to high inter- and intra-patient pharmacokinetic variability. CSA concentration measured 2 hours after administration($C_2$) has better correlation with the AUC than $C_{min}$ and is an alternative technique that predicts the AUC. Tacrolimus(Tac) has a great deal of inter-individual variability like CSA but intra-individual variability in systemic exposure is considered to be low. Both CSA and Tac are metabolized by a cytochrome P-450 enzyme isoform(CYP3A4). We should consider changing the dosages when CSA or Tac is used in combination with the medicines that inhibit or induce the CYP3A4. In case of steroid-free immunosuppressive therapy, the blood concentration of Tac should be frequently checked and dosage adjustment may be needed.

• Journal of Korea Game Society
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• v.14 no.6
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• pp.39-48
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• 2014

Go is an extremely complex strategy board game despite its simple rules. By using MCTS, the computer Go programs with handicap game have been defeated human Go professionals. MCTS is based on the winning rate estimated by MC simulation rather than strategy concept. Meanwhile Genetic algorithm equipped with an adequate fitness function can find out the best solutions in the game. The game of Tic-Tac-Toe, also known as Naughts and Crosses, is one of the most popular games. We tried to find out the best strategy in the game of Tic-Tac-Toe. The experimental result showed that Genetic algorithm enables to find efficient strategies and can be applied to other board games such as Go and chess.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.56 no.4
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• pp.347-360
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• 2020

In this study, the Bayesian state-space model was used for the stock assessment of the Blackfin flounder. In addition, effective measures for the resource management were presentedwith the analysis on the effectiveness of fisheries management plans. According to the result of the analysis using the Bayesian state-space model, the main biometric value of Blackfin flounder was analyzed as 1,985 tons for maximum sustainable yield (MSY), 23,930 tons for carrying capacity (K), 0.000007765 for catchability coefficient (q) and 0.31 for intrinsic growth (r). Also the evaluation on the biological effect of TAC was done. The result showed that the Blackfin flounder biomass will be kept at 14,637 tons 20 years later given the present TAC volume of 1,761 tons. If the Blackfin flounder TAC volume is set to 1,600 tons, the amount of biomass will increase to 16,252 tons in the future. Lastly, the biological effectiveness of the policy to reduce fishing effort was assessed. The result showed that the Blackfin flounder biomass will be maintained at 13,776 tons if the current fishing efforts (currently hp) level is set and maintained. If the fishing effort is reduced by 20%, it will increase to 17,091 tons in the future. The analysis on the economic effect of TAC showed that NPV will be the lowest at 1,486,410 won in 2038, 20 years after the establishment of 2,500 tons of TAC volume. If the TAC volume is set at 2,000 tons, NPV was estimated to be the highest at 2,206,522,000 won. In addition, the analysis on the economic effect of the policy to reduce the amount of fishing effort found that NPV will be 2,235,592,000 won in 2038, 20 years after maintaining the current level of fishing effort. If the fishing effort is increased by 10%, NPV will be the highest at 2,257,575 won even thoughthe amount of biomass will be reduced.

• Journal of Fisheries and Marine Sciences Education
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• v.26 no.1
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• pp.108-125
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• 2014

Although South Korea had managed fishery resources based on elements included in the fishery like fisheries licence, after agreeing on UN Convention on the law in 1999, it became inevitable to adopt TAC that regulates yield. Therefore, currently operating an indecisive system by maintaining the fisheries license system while applying TAC only to some fisheries. However, it became imperative to find ways to improve the current system as it dose not solve problems such as decrease of fishery resources and catch per unit effort, excessive input of fishing boats, rising costs for fishery management, and shortage of fishery population. For those reasons, it is time to review ITQs, which is recognized globally as the most innovative fisheries management system. To adopt the ITQs, it seems necessary to compare how the fisheries act of New Zealand which is currently most successfully operated and Fisheries Resources Management Act of Korea. To do so, in this study, the provisions on TAC of the two countries are compared to analyze the institutional necessity for Korea to adopt ITQs. The following conclusions have been made : First, it will be necessary to gradually expand the species and fisheries for which TAC is enforced, and accumulate correct data on fisheries resources. Second, while forcing traders to obtain license as well, the species and quantity of traded fisheries must be reported separately for cross-checking with the catch reported by the fisheries. Third, the number of observers must be increased and report the species and quantity of the catch to person in charge at the relevant port, and observers must check the report before disembarkation. Fourth, penalty for violating Fisheries resources management act must be enhanced, especially regarding false report of fishery activities and catch.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.11
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• pp.4282-4290
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• 2010

Recently, business environment is spreading from singular business to supply-chain problem. SCM(Supply Chain Management) is changing from closed and static to opened and dynamic environment, so these environment changes of SCM require to enterprise different approach than past. As supply chain is becoming opened and dynamic, a claim is being naming that converse of real-time the get reaction from to recognizing the level of supply chain problem, grope of alternative plan to solving this problem and choosing optimum alternative plan raise the enterprise competitive. But until present, the research to deal with these changes of SCM is on insufficient situation. Thus in this paper proposes the agent system by a way of realizing dynamic supply chain. The agent is going to accomplish the management activities in real-time depends on environment and given condition and designed for solving problems development and maintenance. Also, algorithms performance of the agent is tested on TAC SCM environment. Agents in TAC SCM are simulations of small manufacturers, who must compete with each other for both supplies and customers, and manage inventories and production facilities.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.30 no.2
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• pp.196-204
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• 2020

Objective: Chronic obstructive pulmonary disease(COPD) is characterized by persistent airflow limitations associated with chronic inflammatory response due to noxious particles or gases in the lung. Increasing oxidative stress associated with COPD. The aim of this study was to evaluate the influencing factors of biomarkers for oxidative stress in retired miners with COPD. Methods: The levels of total peroxide(TPx), total antioxidant capacity(TAC), and oxidative stress index(TPx/TAC ratio, OSI) in plasma as biomarkers for oxidative stress, serum C-reactive protein(CRP) as a biomarker for inflammation, and general characteristics were measured in 93 male subjects with COPD. COPD was defined as post bronchodilator FEV₁/FVC<0.7 by spirometry. Results: Mean levels of TPx(p=0.013), TAC(p=0.010), OSI(p=0.040), and CRP(p=0.024) were higher in current smokers. Levels of TPx(β=0.445, p<0.001), TAC(β=0.490, p<0.001), and OSI(β=0.351, p<0.001) were related to CRP levels, and CRP levels were related to %FEV₁ predicted(β=-0.295, p=0.003) and current smoking(β=0.214, p=0.032). Conclusions: These results suggest that oxidative stress was related to inflammation, and inflammation were related to decreasing %FEV₁ predicted and current smoking in retired miners with COPD.

• Journal of Korean Institute of Industrial Engineers
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• v.39 no.6
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• pp.562-576
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• 2013

Power TAC (Power Trading Agent Competition) is an agent-based simulation for competitions between electricity brokering agents on the smart grid. To win the competition, agents obtain electricity from the electricity wholesale market among the power plants. In this operation, a key to success is balancing the demand of the customer and the supply from the plants because any imbalance results in a significant penalty to the brokering agent. Given the bidding on the wholesale market requires the price and the quantity on the electricity, this paper proposes four different price estimation strategies: exponentially moving average, linear regression, fuzzy logic, and support vector regression. Our evaluations with the competition simulation show which strategy is better than which, and which strategy wins in the free-for-all situations. This result is a crucial component in designing an electricity brokering agent in both Power TAC and the real world.