• Journal of the Mineralogical Society of Korea
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• v.27 no.3
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• pp.125-134
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• 2014

The Janggun mine (Longitude $E129^{\circ}$ 03' 40", Latitude $N36^{\circ}$ 51' 19") was once operated as an underground mine and recently significant amount of mine and leachate water has been discharged from the mine adits and tailing dumps. Mine and leachate waters are characterized by neutral to weakly basic pH values (6.81-9.59). Major cations and anions have concentrations between 6.70-129.80 mg/L of Mg, 289.29-661.02 mg/L of Ca, 4.74-14.38 mg/L of Mn and 1205.00-2448.69 mg/L of $SO{_4}^{2-}$. Brownish yellow precipitates that found in the stream bottom consist of poorly crystallized 2-line ferrihydrite ($Fe_2O_3{\cdot}0.5H_2O$. Scanning electron microscope (SEM) photographs show that brownish yellow precipitates consisted of micro-sized granular particles of about $0.1{\mu}m$ in diameter. Semi-quantitative energy dispersive spectrometry (EDS) analyses show that these samples contained mainly Fe with minor Mn, Ca, Si and As.

• Microbiology and Biotechnology Letters
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• v.40 no.3
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• pp.180-185
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• 2012

Type 2 Diabetes Mellitus, a chronic metabolic disorder which results from a high blood glucose level, is one of the most prevalent and costly diseases of our time. Considering increasing rates of obesity and the aging population in Korea, the number of diabetic patients is likely to rise rapidly in the future. There are five conventional diabetic drugs which work through different mechanisms; sulfonylureas, biguanide, meglitinide, alpha-glucosidase inhibitors, and thiazolidinedione. Although they all have antidiabetic effects, some side effects such as hypoglycemia, weight gain and gastrointestinal intolerance are associated with them. Incretin based therapies, utilizing glucagon-like peptide-1 (GLP-1) and dipeptidyl peptidase-4 (DPP-4) inhibitors, which have a lower risk of adverse side effects, have recently been introduced. At present PPAR-targeting drugs are being actively developed. In this research review, particular emphasis has been placed on the current trends and possible biological targets for the new generation of antidiabetic drugs.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.10
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• pp.1205-1215
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• 2017

In this study, the hydrolysis rate of palm kernel oil (HPKO) and shea butter were compared by in vitro digestion to develop low-digestible fats. HPKO exhibited a higher hydrolysis rate than shea butter. The initial rate and ${\Phi}max$ value of HPKO were 0.315 mM/s and 78.0%, while the corresponding values for shea butter were 0.117 mM/s and 41.4%. When the two fats were blended at various ratios, the hydrolysis rate, in terms of the ${\Phi}max$ value, was similar to that of shea butter until 2:8 (HPKO : shea butter, w/w). After the analysis of triacylglycerol species and the positional fatty acid composition, the factors that affected the hydrolysis rate were determined. The results suggest that the low hydrolysis rate of shea butter would be due mostly to the stearic acid located at the sn-1,3 positions of triacylglycerol molecules. These properties of shea butter are expected to be the nutritional benefits as a low-digestible fat in foods.

• Microbiology and Biotechnology Letters
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• v.40 no.3
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• pp.197-207
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• 2012

This study investigated the role of plasmids and their relationship with the multiple antibiotic resistance of 30 Vibrios sp. isolated from molluscs and crustaceans sampled from the Kerala coastal waters of India. The biochemical identification and antibiotic resistance profiles were determined, followed by the plasmid profiles, conjugation and transformation efficiencies. The results showed a considerable difference in the level of bacterial resistance to various antibiotics; while all 30 strains were found to be MAR Vibrios sp. and their resistance patterns varied. All the strains were resistant to amoxycillin, ampicillin and carbeniciliin. 87% were resistant to rifampicin; 74% to cefuroxime; 67 to streptomycin; 53% to norfloxacin and ciprofloxacin and 47% to furazolidone and nalidixic acid. In addition to their antibiotic resistance, the plasmid DNA of the MAR Vibrios strains isolated from the molluscs and crustaceans was also studied. Nine strains isolated from crustaceans and molluscs were found to harbor 1-3 plasmids with sizes varying from 5. 98 kb to 19. 36 kb. The average transformation efficiency was about $5{\times}10^{-8}$ and the conjugation efficiency varied from $2.1{\times}10^{-3}$ to $10^{-9}$. A further study of antibiotic resistance patterns may be useful to test the extent of drug resistance in seafoods and help to devise a nationwide antibiotic policy.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.1205-1206
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• 2008

본 실험에서는 CMOS 공정에서 사용하는 실리콘 트렌치 공정을 이용하여 분절된 트렌치 바디 접촉구조를 형성, 60 V급 전력 MOSFET 소자를 제작하였으며, 결과 소자의 면적을 증가시키지 않고도 제어되지 않은 유도성 스위칭 (UIS) 상황에서 낮은 전도 손실과 높은 항복 에너지 ($E_{AS}$)를 구현하였다. 분절된 트렌치 접촉구조는 소자의 사태 파괴시 n+ 소스 아래의 정공전류를 억제한다. 이는 트렌치 밑 부분에서부터 이온화 충돌이 일어나기 때문이며, 이는 기생 NPN 바이폴라 트랜지스터의 활성화를 억제하여 항복 에너지를 증가시킨다. 기존 소자의 항복 전압은 69.4 V이고 제안된 소자의 항복 전압은 60.4 V로 13% 감소하였지만, 항복 에너지의 경우, 기존소자가 1.84 mJ인데 반하여 제안된 소자는 4.5 mJ로 144 % 증가하였다. 트렌치의 분절 구조는 n+ 소스의 접촉영역을 증가시켜 온 저항을 감소시키며 트렌치 바디 접촉구조와 활성영역의 균일성을 증가시킨다.

• Microbiology and Biotechnology Letters
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• v.40 no.4
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• pp.356-363
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• 2012

The aim of this study was to utilize rice bran, the main waste product of paddy processing, in xanthan gum production by Xanthomonas campestris fermentation. Deffated rice bran was enzymatically hydrolyzed using cellulase, gluco-amylase, alpha-amylase and xylanase at various pHs and temperatures within 0-12 h. The highest sugar content reached at $35^{\circ}C$, pH 5.5 in 6 h with 41.66%. The enzymatic hydrolysate was used as the carbon source for xanthan gum production by X. campestris NRRL B-1459 and X. campestris pv. campestris. The highest productivities obtained were 21.87 and 17.10 g/L, respectively. Viscosity measurement for the obtained xanthan gums and commercial gum was carried out in gum solutions at various pHs and temperatures. The highest viscosity was reached with 1% gum solutions at $20^{\circ}C$ and pH 5.5 for all gums with viscosity values of 470, 131 and 138 mPa sec, respectively. This work has provided relevant scientific information about the use of rice bran, an abundant agroindustrial residue, to produce xanthan gum.

• Proceedings of the Korean Geotechical Society Conference
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• 2005.03a
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• pp.1205-1210
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• 2005

The behavior of rock mass and solute(e.g. groundwater, radioactivity) flow in fractured rock can be directly influenced by joint roughness. The characteristics of joint roughness is also a main factor for the rock classification(e.g. RMR, Q system) which is usually used in tunnel design. Nevertheless, most of JRC estimation has been carried out only by the examination with the naked eye. This JRC estimation has a lack of objectivity because each investigator judges JRC by his subjective opinion. Therefore, it will be desirable that the assessment of JRC is performed by a numerical analysis which can give a quantitative value corresponding to the characteristics of a roughness curve. Meanwhile, roughness curves for joint surfaces which are observed in drill cores have been obtained only along linear profiles. Although roughness curves are measured in the same joint surface, they can frequently show diverse aspects in a standpoint of roughness characteristics. If roughness curves can be measured along the elliptical circumferences of joint surfaces from core scanning images or Televiewer images, they will certainly be more comprehensive than those measured along linear profiles for roughness characteristics of joint surfaces. This study is focus on dealing with (1) extracting automatically roughness curves from core scan image or Televiewer image, (2) improving the accuracy of quantitative assessment of JRC using fractal dimension concept.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.10
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• pp.1200-1205
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• 2014

The effect of nanofluids on the heat transfer performance of a pulsating heat pipe has been experimentally investigated. Water-based diamond nanofluid and aluminium oxide ($Al_2O_3$) nanofluid were tested in the concentration range of 0.5-5%. The pulsating heat pipe was constructed using clear Pyrex tubes of 1.85 mm in inner diameter in order to visualize the pulsating action. The total number of turns was eight each for heated and cooled parts. The supply temperatures of heating water and cooling water were fixed at $80^{\circ}C$ and $25^{\circ}C$ respectively. The liquid charging ratio of the nanofluid was 50-70%. The test results showed that the case of 5% concentration of diamond nanofluid showed 18% increase in heat transfer rate compared to pure water. The case of 0.5% concentration of $Al_2O_3$ nanofluid showed 24% increase in heat transfer rate compared to pure water. But the increase of $Al_2O_3$ nanofluid concentration up to 3% did not show further enhancement in heat transfer. It is also observed that the deposited nanoparticles on the tube wall played a major role in enhanced evaporation of working fluid and this could be the reason for the enhancement of heat transfer by a nanofluid, not the enhanced thermal conductivity of the nanofluid.

• Journal of International Academy of Physical Therapy Research
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• v.8 no.2
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• pp.1201-1205
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• 2017

The purpose of this case study was to investigate the effects of thoracic mobilization and manipulation on a patient with upper thoracic pain. The subject had been complaining of upper thoracic pain for the last 4 months. On the X-ray, T3 and T4 spinous process were located on the left side of the vertical axis. First, transverse mobilization was applied from left to right at the T3-T4 and then thoracic manipulation was performed. The intervention methods of mobilization and manipulation were based on the concept of Maitland manual therapy. The subject underwent a total of 20 sessions (five times per week for four weeks). The thoracic pain and vertebral rotation angle were measured to examine the effect of the intervention. The thoracic pain score decreased (from 4.0 to 1.5) and the angle of thoracic vertebral rotation decreased (from $70{\underline{\circ}}$ to $4.0{\underline{\circ}}$). These results suggest that applied mobilization and manipulation in patients with a primary complaint of thoracic pain decreasing the thoracic pain and vertebral rotation angle.

• Journal of Microbiology and Biotechnology
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• v.26 no.7
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• pp.1198-1205
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• 2016

Lactic acid bacteria (LAB) have beneficial effects on intestinal health and skin diseases. Lipoteichoic acid (LTA), a cell wall component of gram-positive bacteria, is known to induce the production of several cytokines such as TNF-α, IL-1β, and IL-8 and affect the intestinal microflora, anti-aging, sepsis, and cholesterol level. In this study, Weissella cibaria was isolated from Indian dairy products, and we examined its immune-enhancing effects. Live and heat-killed W. cibaria did not induce the secretion of immune-related cytokines, whereas LTA isolated from W. cibaria (cLTA) significantly increased the secretion of TNF-α, IL-1β, and IL-6 in a dose-dependent manner. cLTA increased the phosphorylation of nuclear factor kappa-light-chain-enhancer of activated B cells, p38 mitogen-activated protein kinases, and c-Jun N-terminal kinases in THP-1 cells. The secretion of TNF-α and IL-6 was also increased in the cLTA-treated mouse splenocytes. These results suggest that cLTA, but not W. cibaria whole cells, has immune-boosting potential and can be used to treat immunosuppression diseases.