• 생물정신의학
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• 제5권2호
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• pp.278-282
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• 1998

Various neurotransmitters have been proposed as possible mediators of penile erection. Especially, norepinephrine and serotonin might have a important role in sexual arousal and penile erection. And it could be hypothesized that the psychogenic impotence is associated with the depletion or imbalance of norepinephrine and serotonin from evidences, such as the symptomatic manifestation of depression and the antidepressantinduced sexual dysfunction. The authors investigates the association of norepienphrine and serotonin with psychogenic impotence. The psychogenic impotent group(PIG) consisted of twenty-three patients with psychogenic impotence and the controlled group(CG) consisted of twenty-seven patients without psychogenic impotence. PIG had no organic cause accounting for their erectile dysfunction. The Beck Depression Inventory(BDI) and the State-Trait Anxiety Inventory(STAI) were applied to each subject to assess mood, state anxiety(SA) and trait anxiety(TA). Plasma norepinephrine level from systemic blood and 5-hydroxyindoleacetic acid(HIAA) levels from 24-hours urine were measured in each subject. The mean score of BDI of PIG was significantly higher than that of CG(p=0.015). PIG had a tendency of higher TA compared with CG(p=0.054). And also SA was higher in PIG, but did not show significant difference(p=0.193). The level of norepinephrine was significantly lower in patient with psychogenic impotence(p=0.000). And the level of 24-hours urine 5-HIAA was lower in PIG but did not show significant difference(p=0.494). Although the authors did not exclude depressive disorders in PIG, the present findings suggest that psychogenic impotence might have higher depressive mood and trait anxiety, and be associated with the depletion of norepinephrine in systemic blood.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1998년도 하계학술대회 논문집 C
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• pp.1166-1169
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• 1998

The Load characteristic of electric railway requires the power demand of the high capacity which amplitude is spacial-temporally fluctuated due to frequent starting and stopping with large tractive force. The conventional electric railway mainly consists of the resistance controlled and the thyristor controlled locomotives, are compensated for their bad characteristics of the power factor$(70\sim80%)$ with installation of another capacitor improving power factor at the substation. Since 1994, VVVF train car with good characteristics of power factor(100%) have been introduced and operated in Kwa-Chon Line. From the present technical tendency, it is judged that introduction of the locomotive with various controlled methods is necessary. The protective equipments installed at the substation are complicated and various aspects to detect faults and reduce their extension, so the universal countermeasures are required. Specially in the case of the fault occurrence it is difficult to calculate the fault location because of the change in the contactline constant according to modifying the characteristics of the contactline (the dualized catenary wire and extension, etc), so much time is required for the detection of fault location. In BT-fed method distance-relays and fault-locators are not installed, we have so many difficulties in the quick accident recovery.

• 동아시아식생활학회지
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• 제15권2호
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• pp.137-151
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• 2005

It is estimated that sesame spread to Korea about B.C.1000 years and people cultivated sesame and ate sesame-oil age of three-nations. In the Koryo dynasty, sesame was cultivated as the major crop and there were specialists for making sesame oil. The sesame oil was enough for the both upper and lower classes. In the Chosun dynasty, it was introduced widely the method of sesame and deul-sesame (Perilla japonica) cultivation, the way of keeping sesame oil, and how to make sesame oil. Also, there were several ways of making sesame oil; press oil from raw sesame, or from roasting, boiling, and steaming sesame and etc. Even though sesame-oil and sesames were consumed in large quantities to cook Chan (찬 side dishes) and Byung-gwa (병과 Korean traditional dessert), most of common people could not use freely because it was expensive. You-mil-gwa (유밀과) took always a major dishes in the ceremony or party of the royal classes to the ordinary classes in the Chosun dynasty. Sesames and Sesame-oil made a major role in adding flavor to Chan-mul and Coookies in the Korean traditional cuisine. Especially, sesame-oil was consumed a lot to cook You-mil-gwa, You-kwa (유과), You-jeon-byung (유전병 fried rice cake) and Yak-bab (약밥). Roasted sesame and black sesame were used to cook Da-sik (다식), Gang-jung, and rice cake. Sesame oil and sesame was the major part of vegetable dishes such as Na-mul and it was used to add flavor to steamed, roasted and, pan-fried dishes and to roast, fry, and stew food. Heuk-im-ja-jook(black sesame porridge) and Im-ja-su-soup(임자수탕).

• 동아시아식생활학회:학술대회논문집
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• 동아시아식생활학회 2004년도 참깨과학 국제학술대회 발표 논문집
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• pp.145-174
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• 2004

It is estimated that sesame spread to Korea about BC 1000 years and people cultivated sesame and ate sesame-oil e age of three-nations. In the Koryo dynasty, sesame was cultivated as the major crop and there were specialists for making sesame oil. The sesame oil was enough for the both upper and lower classes. In the Chosun dynasty, it was introduced widely the method of sesame and deul-sesame (Perilla japonica) cultivation, the way of keeping sesame oil, and how to make sesame oil. Also, there were several ways of making sesame oil; press oil from raw sesame, or from roasting, boiling, and steaming sesame and etc. Even though sesame-oil and sesames were consumed in large quantities to cook Chan(饌, side dishes) and Byung-gwa(餠菓, Korean traditional dessert), most of common people could not use freely because it was expensive. You-mil-gwa(油蜜菓) took always a major dishes in the ceremony or party of the royal classes to the ordinary classes in the Chosun dynasty. Sesames and Sesame-oil made a major role in adding flavor to Chan-mul and Coookies in the Korean traditional cuisine. Especially, sesame-oil was consumed a lot to cook You-mil-gwa, You-kwa(油菓), You-jeon-byung(油煎餠 fried rice cake) and Yak-bab(藥飯). Roasted sesame and black sesame were used to cook Da-sik(茶食), Gang-jung, and rice cake. Sesame oil and sesame was the major part of vegetable dishes such as Na-mul and it was used to add flavor to steamed, roasted and, pan-fried dishes and to roast, fry, and stew food. Heuk-im-ja-jook(black sesame porridge) and Im-ja-su-soup (荏子水湯).

• 수면정신생리
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• 제15권1호
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• pp.39-43
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• 2008

목 적 : 하지불안증후군(restless legs syndrome ; RLS)의 병인은 아직 불명확하지만, 도파민 결핍과 유전적 소인이 흔히 제기된다. RLS는 도파민수용체를 차단하는 항정신 병약물을 복용하는 환자들에서 더 흔히 발생하는 것으로 보인다. 본 연구에서는 정신분열병환자에서 항정신병약물에 의해 유발된 RLS와 도파민 수송체(dopamine transporter gene ; DAT1) 유전자가 연관이 있는지 알아보고자 하였다. 방 법: International Restless Legs Syndrome Study Group의 진단기준으로 190명의 한국인 정신분열병 환자들을 대상으로 RLS에 대해서 평가하였다. 유전자형분석은 중합효소연쇄반응기법을 사용하여 DAT1 유전자의 40 염기쌍(basepair) variable number of tandem repeat(VNTR)에 대해서 시행되었다. 결 과 : 우리는 44명의 RLS군과 146명의 비RLS군으로 환자들을 분류하였다. 두 군간의 유전자형과 대립유전자 빈도의 차이를 분석한 결과 유의한 차이를 발견할 수 없었다. 결 론 : 이 연구는 DAT1 유전자의 40 bp VNTR 다형성이 항정신병약물로 유발된 RLS와 연관이 없다는 것을 시사한다. 이 결과를 확증하기 위해서는 향후 보다 대규모의 연합연구가 필요할 것이다.

• 한국조리학회지
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• 제21권3호
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• pp.248-258
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• 2015

본 연구는 수삼정과를 저열량 감미료인 자일리톨, 올리고당, 스테비오시드, 에리스리톨을 이용하여 전기밥솥으로 205분 제조하여 품질 특성을 비교하였다. 수삼정과의 수분 함량은 시료 간에 유의적인 차이를 나타내었고, 스테비오시드는 다른 시료들에 비해 수분 함량이 현저하게 높았다. 당도는 시료 간에 유의적인 차이를 보였다. 설탕으로 전기밥솥에 제조한 수삼정과의 명도와 적색도는 유의적으로 비슷한 경향을 보였으며, 자일리톨로 제조한 수삼정과의 황색도가 유의적으로 가장 낮았다. 수삼에 설탕을 넣고 제조한 대조군의 경도는 설탕으로 제조한 수삼정과가 유의적으로 가장 컷으며, 부착성은 시료 간에 유의적인 차이를 보였으나, 경도에 따른 뚜렷한 경향을 나타내지는 않았다. 탄력성은 설탕으로 제조한 것이 가장 컸고, 씹힘성은 시료 간에 유의적인 차이를 보였다. 검성은 유의적인 차이를 보이지는 않았으며, 응집성은 자일리톨과 올리고당으로 제조한 수삼정과의 응집성이 유의적으로 가장 컸다. 관능적인 특성을 검토해본 결과, 정과의 외관, 향, 맛, 종합적인 기호도에서 선호한 올리고당으로 제조한 수삼정과를 다른 대체 감미료로 만든 시료에 비해 높은 점수를 얻었으며, 정과의 윤기, 갈색의 정도, 인삼의 향, 맛도 선호하였다. 따라서 설탕을 대신하여 올리고당을 사용하여 정과를 제조하면 현대인들의 건강에 대한 염려에도 부합하는 칼로리가 낮은 정과의 제조도 가능함을 알 수 있었다.

• 생물정신의학
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• 제2권1호
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• pp.131-139
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• 1995

Clozapine은 정형적 항정신병약물에 반응하지 않는 불응성 정신분열증 환자에게 효과적이며, 추체외로부작용이 적은 비정형적 향정신병약물로 보고되고있다. 따라서 저자들은 불응성 정신분열증환자를 대상으로 clozapine의 항정신병효과 및 부좌용에 대해 대표적 전형적 항정신병약물인 haloperidol과 비교연구하였다. 대상환자를 clozapine투여군(17명) 과 haloperidol 투여군 (16명)으로 나누어 12주 동안 각각의 약물을 투여하는 전향적 개방대조연구를 하였다. 두가지 약물의 치료효과와 부작용은 BPRS, PANSS, Simpson-Angus Rating Scale 및 Adverse Events-Somatic Symptoms를 사용하여 평가하였다. 약물투여 12주후 clozapine투여군이 76.5% 에서 치료반응을 보인데 비해 haloperidol투여군은 31.2%의 치료반응을 보임으로써 두약물 투여군간에 유의한 차이가 있었다. BPRS와 PANSS 척도상 clozapine투여군이 haloperidol투여군에 비하여 BPRS, PANSS 양성증상 및 일반증상 척도는 약물투여 8주후부터, PANSS 음성척도는 약물투여 4주후부터 12주까지 일관성있게 지속적으로 의미있는 호전을 보였다. Clozapine투여군에서는 타액분비(70.6%), 졸리움(52.9%), 변비(29.4%) 및 저혈압(23.4%)이, haloperidol투여군은 진전(37.5%), 정좌불능(25.0%), 강직(18.8%) 및 무운동(18.8%)이 흔히 보고되었다. 하지만 두약물 투여군 모두에서 대부분 경미하고 환자가 견딜 정도였다. Clozapine투여군에서 약물투여 전에 비해서 약물투여 12주후 백혈구와 호중구의 유의한 변화는 없었다. 이상의 결과를 종합해볼 때, clozapine은 정형적 항정신병약물에 치료효과가 없거나 추체외로부작용 때문에 약물투여가 어려운 경우의 한국인 불응성 정신분열증환자에게 효과적인 비정형적 항정신병약물이다.

• 정신신체의학
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• 제18권1호
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• pp.30-39
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• 2010

연구목적 : 임상현장에서 주로 환자나 간호사의 주관적인 수면보고에 의존하여 수면을 평가하고 있다. 본 연구에서는 주관적 수면평가와 활동기록을 이용한 수면평가를 비교하고자 한다. 방 법 : 32명의 정신과 입원 환자를 대상으로 하였고, 대상자들에게 활동기록기를 이용한 수면평가, 수면일지, 주관적인 수면의 질에 대한 시각적 증상 정도 평가, BDI, STAI를 시행하였다. 간호사도 3일 동안 한 시간마다 환자의 수면을 평가하였다. 결 과 : 환자의 보고와 활동기록기를 이용한 수면측정상 입면잠복시간에서 유의한 차이를 보였다. 환자는 간호사보다 자고 있음에도 깨어있었다고 더 많이 보고하였다. 주관적 수면평가와 활동기록 수면평가의 차이는 불안, 우울과 상관관계를 보였다. 결 론 : 주관적으로 수면의 질을 낮게 평가하는 환자일수록 활동기록기로 측정한 입면잠복시간과 더 큰 차이를 보였고, 우울, 불안 증상이 심한 환자의 수면보고는 활동기록 측정값과 큰 차이를 보였다. 이런 환자들에게 수면의 질에 대한 질문만으로는 정확한 수면평가가 어려우므로 객관적인 수면평가가 필요하겠다.

• 한국식품저장유통학회지
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• 제24권3호
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• pp.406-412
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• 2017

감미료의 종류를 달리하여 제조한 생강정과의 품질 특성 및 항산화성을 분석하여 품질이 향상된 생강정과를 제조하고자 하였다. 열수처리한 생강을 설탕, 자일리톨, 꿀, 올리고당과 2:1의 비율로 약한불에서 졸여 정과를 제조하였다. 생강정과의 수분함량은 꿀과 올리고당 정과가 높았으며 설탕과 자일리톨 정과는 수분함량이 적어 표면에 결정이 생성되었다. 가용성 고형분 함량은 자일리톨이 $7.07^{\circ}Brix$로 가장 높았다. 정과의 pH는 올리고당이 5.82로 가장 낮았으며 설탕이 6.59로 가장 높은 값을 나타내었다. 자일리톨로 제조한 정과의 명도가 가장 높았으며 꿀로 만든 정과가 적색도가 1.02로 가장 높은 값을 나타내었고 설탕, 자일리톨, 올리고당 순으로 나타났다. 자일리톨 정과의 hardness와 chewiness 값이 가장 높았으며 다른 항목에서는 유의적인 차이가 나타나지 않았다. 유리당 함량은 설탕으로 제조한 정과의 sucrose, glucose, galactose 함량이 가장 높았으며 자일리톨 처리구의 경우 당 성분이 극히 미량이거나 검출되지 않았다. 꿀로 제조한 생강정과의 DPPH, ABTS 라디칼 소거능이 가장 높게 나타났으며 총 페놀성 화합물 함량도 꿀이 가장 높았고 자일리톨, 올리고당, 설탕 순으로 나타났다. 관능검사에서 꿀과 올리고당으로 제조한 정과가 외관과 색의 선호도가 유의적으로 높게 나타났으며 종합적 기호도는 꿀, 설탕, 올리고당, 자일리톨 순으로 나타났다. 이상의 실험 결과로 미루어 보아 생강정과를 제조할 때 꿀을 사용하는 것이 정과의 품질과 기호도를 높일 수 있을 것으로 생각된다.

• 대한한의학원전학회지
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• 제9권
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• pp.432-552
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• 1996

The influence of the four noted physicians of Geum-Won era(金元代) on the completion of the medicine in the Chosun dynasty(朝鮮朝) can be summarized as follows. 1. The four noted physicians of Geum-Won era were Yoo-Wan-So(劉完素), Jang-Jong-Jung(張從正), Lee-Go(李杲), Ju-Jin-Heung(朱震亨). 2. Yoo-Wan-So(劉完索) made his theory on the basic of Nae-Kyung("內經") and Sane-Han-Lon("傷寒論"), his idea of medicine was characterized in his books, for exemple, application of O-Oon-Yuk-Ki(五運六氣), Ju-Wha theory(主火論) and hang-hae-seng-je theory(亢害承制論). from his theory and method of study, many deviations of oriental medicine occurred. He made an effort for study of Nae-Kyung, which had been depressed for many years, on the contrary of the way old study that Nae-Kyung had been only explained or revised, he applied the theory of Nae-Kyung to clinical care. The theory of Yuk-Gi-Byung-Gi(六氣病機) and On-Yeul-Byung(溫熱病) had much influenced on his students and posterities, not to mention Jang-Ja-Wha and Ju-Jin-Heung, who were among the four noted physicians therefore he became the father of Yuk-Gi(六氣) and On-Yeul(溫熱) schools. 3. Jang-Jong-Jung(張從正) emulated Yoo-Wan-So as a model, and followed his Yuk-Gi-Chi-Byung(六氣致病) theory, but he insisted on the use of the chiaphoretic, the emetic and the paregoric to get rid of the causes, specially he insisted on the use of the paregoric, so they called him Gong-Ha-Pa(攻下派). He insisted on the theory that if we would strenthen ourselves we should use food, id get rid of cause, should use the paregoric, emetic and diaphoretic. Jang-Jong-Jung'S Gang-Sim-Wha(降心火) theory, which he improved Yoo-Wan-So's Han-Ryang(寒凉) theory influenced to originate Ju-Jin-Heung'S Ja-Eum-Gang-Wha(滋陰降火) theory. 4. Lee-Go(李杲) insisted on the theory that Bi-Wi(脾胃) played a loading role in the physiological function and pathological change, and that the internal disease was originated by the need of Gi(氣) came from the disorder of digestive organs, and that the causes of internal disease were the irregular meal, the overwork, and mental shock. Lee-Go made an effort for study about the struggle of Jung-Sa(正邪) and in the theory of the prescription he asserted the method of Seung-Yang-Bo-Gi(升陽補氣), but he also used the method of Go-Han-Gang-Wha(苦寒降火). 5. The authors of Eui-Hak-Jung-Jun("醫學正傳"), Eui-Hak-Ib-Moon("醫學入門"), and Man-Byung-Whoi-Choon("萬病回春") analyzed the medical theory of the four noted physicians and added their own experiences. They helped organizing existing complicated theories of the four noted physicians imported in our country, and affected the formation of medical science in the Choson dynasty largely. Eui-Hak-Jung-Jun("醫學正傳") was written by Woo-Dan(虞槫), in this book, he quoted the theories of Yoo-Wan-So, Jang-Jong-Jung, Lee-Go, Ju-Jin-Heung, especially, Ju-Jin-Heung was respected by him, it affected the writing of Eui-Lim-Choal-Yo("醫林撮要"). Eui-Hak-ib-Moon("醫學入門"), written by Lee-Chun(李杲), followed the medical science of Lee-Go and ju-jin-heung from the four noted physicians of Geum-Won era. Its characteristics of Taoism, idea of caring of health, and organization affected Dong-Eui-Bo-Kham("東醫寶鑑"). Gong-Jung-Hyun(龔延賢) wrote Man-Byung-Whoi-Choon("萬病回春") using the best part of the theories of Yoo-Wan-So, Jang-Jong-Jung, Lee-Go, Ju-Jin-Heung, this book affected Dong-Eui-Soo-Se-Bo-Won("東醫壽世保元") partly. 6. our medical science was developed from the experience of the treatment of disease obtained from human life, these medical knowledge was arranged and organized in Hyang-Yak-Jib-Sung-Bang("鄕藥集成方"), medical books imported from China was organized in Eui-Bang-Yoo-Chwi("醫方類聚"), which formed the base of medical development in the Chosun dynasty. 7. Eui-Lim-Choal-Yo("醫林撮要") was written by Jung-Kyung-Sun(鄭敬先) and revised by Yang-Yui-Soo(楊禮壽). It was written on the base of Woo-Dan's Eui-Jung-Jun, which compiled the medical science of the four noted physicians of Geum-Won era. It contained confusing theories of the four noted physicians of Geum-Won era and organized medical books of Myung era, therefore it completed the basic form of Byun-Geung-Non-Chi (辨證論治) influenced the writing of Dong-Eui-Bo-Kham("東醫寶鑑"). 8. Dong-Eui-Bo-Kham("東醫寶鑑") was written on the base of basic theory of Eum-Yang-O-Haeng(陰陽五行) and the theory of respondence of heaven and man(天人相應說) in Nae-Kyung. It contained several theories and knowledge, such as the theory of Essence(精), vitalforce(氣), and spirit(神) of Taoism, medical science of geum-won era, our original medical knowledge and experience. It had established the basic organization of our medical science and completed the Byun-Geung-Non-Chi (辨證論治). Dong-Eui-Bo-Kham developed medical science from simple medical treatment to protective medical science by caring of health. And it also discussed human cultivation and Huh-Joon's(許浚) own view of human life through the book. Dong-Eui-Bo-Kham adopted most part of Lee-Go(李杲) and Ju-Jin-Heung's(朱震亨) theory and new theory of "The kidney is the basis of apriority. The spleen is the basis of posterior", so it emphasized the role of spleen and kidney(脾腎) for Jang-Boo-Byung-Gi(臟腑病機). It contained Ju-Jin-Heung's theory of the cause and treatment of disease by colour or fatness of man(black or white, fat or thin). It also contained Ju-Jin-Heung's theory of "phlegm break out fever, fever break out palsy"(痰生熱 熱生風) and the theory of Sang-Wha(相火論). Dong-Eui-Bo-Kham contained Lee-Go's theory of Wha-Yu-Won-Bool-Yang-Lib (火與元氣不兩立論) quoted the theory of Bi-Wi(脾胃論) and the theory of Nae-Oi-Sang-Byun(內外傷辨). For the use of medicine, it followed the theory by Lee-Go. lt used Yoo-Wan-So'S theory of Oh-Gi-Kwa-Keug-Gae-Wi-Yul-Byung(五志過極皆爲熱病) for the treatment of hurt-spirit(傷神) because fever was considered as the cause of disease. It also used Jang-Jons-Jung's theory of Saeng-Keug-Je-Seung(生克制勝) for the treatment of mental disease. 9. Lee-je-ma's Dong-Eui-Soo-Se-Bo-Won("東醫壽世保元") adopted medical theories of Song-Won-Myung era and analyzed these theories using the physical constitutional theory of Sa-Sang-In(四象人). It added Dong-Mu's main idea to complete the theory and clinics of Sa-Sang-Eui-Hak(四象醫學). Lee-Je-Ma didn't quote the four noted physicians of Geum-Won era to discuss that the physical constitutional theory of disease and medicine from Tae-Eum-In(太陰人), So-Yang-In(少陽人), So-Eum-In(少陰人), and Tae-Yang-In(太陽人) was invented from their theories.