• Radiation Oncology Journal
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• 제33권2호
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• pp.155-159
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• 2015

We present a case of cervical cancer treated by concurrent chemoradiation. In radiation therapy part, the combination of the whole pelvic helical tomotherapy plus image-guided brachytherapy with megavoltage computed tomography of helical tomotherapy was performed. We propose this therapeutic approach could be considered in a curative setting in some problematic situation as our institution.

• Radiation Oncology Journal
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• 제32권2호
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• pp.57-62
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• 2014

Purpose: To evaluate association between equivalent dose in 2 Gy (EQD2) to rectal point dose and gastrointestinal toxicity from whole pelvic radiotherapy (WPRT) and intracavitary brachytherapy (ICBT) in cervical cancer patients who were evaluated by rectosigmoidoscopy in Faculty of Medicine, Chiang Mai University. Materials and Methods: Retrospective study was designed for the patients with locally advanced cervical cancer, treated by radical radiotherapy from 2004 to 2009 and were evaluated by rectosigmoidoscopy. The cumulative doses of WPRT and ICBT to the maximally rectal point were calculated to the EQD2 and evaluated the association of toxicities. Results: Thirty-nine patients were evaluated for late rectal toxicity. The mean cumulative dose in term of EQD2 to rectum was 64.2 Gy. Grade 1 toxicities were the most common findings. According to endoscopic exam, the most common toxicities were congested mucosa (36 patients) and telangiectasia (32 patients). In evaluation between rectal dose in EQD2 and toxicities, no association of cumulative rectal dose to rectal toxicity, except the association of cumulative rectal dose in EQD2 >65 Gy to late effects of normal tissue (LENT-SOMA) scale ${\geq}$ grade 2 (p = 0.022; odds ratio, 5.312; 95% confidence interval, 1.269-22.244). Conclusion: The cumulative rectal dose in EQD2 >65 Gy have association with ${\geq}$ grade 2 LENT-SOMA scale.

• Radiation Oncology Journal
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• 제2권2호
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• pp.281-285
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• 1984

The authors have intended to measure intrinsic dose distribution by Farmer dosimeter in irregularly shaped fields such as L.M and T shape models in order to determine dose inhomogeneity in those models. We made 2 off·axis points in each model and measured the depth dose at 1.5, 5 and 9cm below surface. The results showed $l\~3\%$ dose discrepancy between 2 points. We also measured the depth dose by geometric approximation and computer calculation in those models, and came to the conclusion that computer calculation using Clarkson's principle is simpler and the measurements are closer to the ideal data obtained by the experiment in three models of irregularly shaped fields than those of geometric approximation method.

• Radiation Oncology Journal
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• 제9권2호
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• pp.361-367
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• 1991

This paper on the status of radiotherapy machine and related facilities, clinical activities and radiation safety management is based on the statistical data which collected through the questionaire sent to a total number of 37 hospitals holding the Department of Therapeutic Radiology in Korea. It is true that the quality of instruments installed in the hospitals equal to that of the instrument in the industrialized conuntries' hospitals. But the clinical specialists and physicists who can utilize such instruments fall short of the required number, which might be a main factor in hindering the development of therapeutic radiology of Korea. According to the nation-wide cancer statistics, we can estimate the number of annual cancer patients as 45,000 to 50,000. As a result, probably around 25,000 should receive radiation therapy. It is expected that in the future the number of cancer patients to whom radiation therapy should be applied will become twice as much as that of the cancer patients in 1990. Given such a condition, the problem facing the Korean Society of Therapeutic Radiology now is to increase the number of medical doctors and physicists.

• Radiation Oncology Journal
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• 제18권1호
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• pp.46-50
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• 2000

8년전 완전방실차단으로 심박조율기를 장착한 70세 여자환자에서 갑상선암에 의한 경부 종창에 의한 동통과 기관내 출혈로 인하여 경부 및 종격동에 고식적 방사선치료를 시행하였다. 저자들은 이에 대한 증레보고와 문헌고찰을 하고자 한다.

• Radiation Oncology Journal
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• 제12권2호
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• pp.219-223
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• 1994

This paper describes the basic data measurements for total body irradiation with 6 Mv photon beam including compensators design. The technique uses bilateral opposing fields with tissue compensators for the head, neck, lungs, and legs from the hip to toes. In vivo dosimetry was carried out for determining absorbed dose at various regions in 7 patients using diode detectors(MULTIDOSE,k Model 9310, MULTIDATA Co., USA). As a results, the dose uniformity of${\pm}3.5{\%}$(generally, within${\pm}10{\%}$can be achieved with out total body irradiation technique.

• 한국의학물리학회지:의학물리
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• 제22권1호
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• pp.12-17
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• 2011

본 연구는 노발리스용 치료테이블(couch top)을 투과하는 광자선의 감쇠율(attenuation rate)을 기하학적 모델을 통해 계산하고 보정함으로써, 치료부위에 정확한 선량이 전달되게 하는데 그 목적이 있다. 실험은 치료테이블을 투과하는 광자선의 투과율과 감쇠율을 기하학적인 모델에 의해 예측하고 이를 바탕으로 실험적으로 측정된 것을 비교 및 분석하였다. 그 결과 기하학적 모델에 의해 예측된 값과 실험값이 매우 잘 일치하는 것으로 나타났다. 또 실제 임상적용의 가능여부를 판단하기 위하여, 척추 방사선수술(spine radiosurgery)환자의 치료계획에 모델링화한 감쇠율을 보정한 뒤 측정한 중심점 선량과 그렇지 않은 것을 비교하였더니, 전자가 치료계획된 것과의 오차율이 감소함을 보였다. 본 논문에서는 치료테이블을 투과하는 광자선의 기하학적 모델을 통해 투과율과 감쇠율을 계산하고 이를 실험적으로 증명하였다. 이 방법은 노발리스를 이용한 방사선 수술뿐만 아니라 일반적인 방사선 치료에 있어서도 매우 유용할 것으로 판단된다.

• Radiation Oncology Journal
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• 제2권2호
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• pp.303-309
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• 1984

Radiation therapy(RT) has been used in the treatment of breast cancer for over 80years. Technically, it should include a part or all of such areas as chest wall or breast, axilla, internal mammary nodes (IM) and supraclavicular nodes (SCL). Authors tried three-field technique for the treatment of breast cancer using 6-MV linear accelerator, exclusively the department of radiology. Kang-Nam St. Mary's Hospital, at Catholic Medical College. The field junction was checked by a Phantom study and radiation doses measured by film densitometry and TLD. The 3 fields we used in this study were two isocentric opposing tangential fields encompassing the breast, chest wall and occasionally IM and one single anterior field encompassing the axilla and SCL. sing appropriate beam blocks and boluses, we were able to avoid unwanted intrinsic divergency of photon beam. Blocking also enabled us to set-up precise radiation field with ease.

• Radiation Oncology Journal
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• 제7권1호
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• pp.45-50
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• 1989

From Feb.1985 to Feb.1988,76 patients with squamous cell carcinoma of the lung treated at the Department of Therapeutic Radiology in Kyungpook National University Hospital were available for the analysis of this study. All patients received radiation of 4000cGy-6600cGy with curative aim. The overall rate of complete response was 25.0% and partial response was 452.6% The complete and partial regression of tumor was 14.3% in patients treated with dose below 5000cGy and 84.1% in the group treated with dose above 5000cGy (p<0.01). The complete response was seen only in the group of patients received radiation at least 6000cGy. The patterns of failure were as follows. The rate of initial intrathoracic recurrence was 52.6% in patients with complete response. The overall rate of failure was 68.8%. Distant metastasis was found in 47.4% of patients. Bone, contralateral lung, and brain were common metastatic sites in decreasing order All of the distant metastases and 80% of local recurrences were found within the first year after treatment.

• Radiation Oncology Journal
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• 제11권2호
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• pp.455-461
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• 1993

Experimental measurements of dose characteristics with pentagonal applicator at nominal energy of 4, 6, 9, 12 and 15 MeV electron beam were performed for intraoperative radiotherapy (IORT) in ML-15MDX linear accelerator. This paper presents the percent depth dose, surface dose, beam flatness and output factors of using the IORT applicator in different electron beam energy. The output factor showed as a 24 percent higher in IORT applicator than that of reference $10{\times}10cm^2$ applicator. The surface dose of using the IORT applicator showed 7.7 and 2.7 percent higher than that of reference field in 4 and 15 MeV electron beam, respectively. In our experiments, the variation of percent depth dose was very small but the output factor and flatnees at 0.5 cm depth have showed a large value in IORT applicator.