• Asian-Australasian Journal of Animal Sciences
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• 제24권12호
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• pp.1651-1659
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• 2011

This study was conducted to detect quantitative trait loci (QTL) for thirteen growth and meat quality traits in pigs by combing QTL experimental populations. Two F2 reference populations that were sired by Korea native pig (KNP) and dammed by Landrace (LN) or Yorkshire (YK) were generated to construct linkage maps using 123 genetic markers (mostly microsatellites) and to perform QTL analysis on porcine chromosomes (SSCs) 1, 2, 3, 6, 7, 8, 9, 11, 13, 14, and 15. A set of line-cross models was applied to detect QTL, and a series of lack-of-fit tests between the models was used to characterize inheritance mode of QTL. A total of 23, 11 and 19 QTL were detected at 5% chromosome-wise level for the data sets of KNP${\times}$LN, KNP${\times}$YK cross and joint sets of the two cross populations, respectively. With the joint data, two Mendelian expressed QTL for live weight and cooking loss were detected on SSC3 and SSC15 at 1% chromosome-wise level, respectively. Another Mendelian expressed QTL was detected for CIE a on SSC7 at 5% genome-wise level. Our results suggest that QTL analysis by combining data from two QTL populations increase power for QTL detection, which could provide more accurate genetic information in subsequent marker-assisted selection.

• Imaging Science in Dentistry
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• 제47권2호
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• pp.99-107
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• 2017

Purpose: Erosions and osteophytes are radiographic characteristics that are found in different stages of temporomandibular joint (TMJ) osteoarthritis. This study assessed the effectiveness of digital subtraction radiography (DSR) in diagnosing simulated osteophytes and erosions in the TMJ. Materials and Methods: Five intact, dry human skulls were used to assess the effectiveness of DSR in detecting osteophytes. Four cortical bone chips of varying thicknesses (0.5 mm, 1.0 mm, 1.5 mm, and 2.0 mm) were placed at the medial, central, and lateral aspects of the condyle anterior surface. Two defects of varying depth (1.0 mm and 1.5 mm) were created on the lateral, central, and medial poles of the condyles of 2 skulls to simulate erosions. Panoramic images of the condyles were acquired before and after artificially creating the changes. Digital subtraction was performed with Emago dental image archiving software. Five observers familiar with the interpretation of TMJ radiographs evaluated the images. Receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic accuracy of the imaging methods. Results: The area under the ROC curve (Az) value for the overall diagnostic accuracy of DSR in detecting osteophytic changes was 0.931. The Az value for the overall diagnostic accuracy of panoramic imaging was 0.695. The accuracy of DSR in detecting erosive changes was 0.854 and 0.696 for panoramic imaging. DSR was remarkably more accurate than panoramic imaging in detecting simulated osteophytic and erosive changes. Conclusion: The accuracy of panoramic imaging in detecting degenerative changes was significantly lower than the accuracy of DSR (P<.05). DSR improved the accuracy of detection using panoramic images.

• 방송공학회논문지
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• 제18권3호
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• pp.380-392
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• 2013

본 논문에서는 키넥트와 퍼지 시스템을 이용하여 골프 스윙 동작을 7가지 구간으로 분류하는 방법을 제안한다. 퍼지 논리의 입력으로 골프 클럽과 클럽의 헤드 위치를 사용하였으며 이 정보는 키넥트로부터 획득한 골퍼의 관절 정보와 컬러 영상 정보로부터 검출하였다. 제안하는 방법은 크게 신체 관절 추출 모듈, 골프 클럽 검출 및 헤드 추적 모듈, 골프 스윙 동작 분류 모듈로 구성되어 있다. 신체 관절 추출 모듈은 키넥트 센서로부터 검출되는 신체 관절 정보 중 골프 클럽의 검출을 위해 손의 좌표를 추출한다. 두 번째 모듈에서는 손의 좌표를 기준으로 허프 직선 변환 알고리즘을 사용하여 골프 클럽과 골프 클럽의 헤드를 검출한다. 마지막으로 인식 오류를 줄이고 동작별 인식 성능을 향상시키기 위해 퍼지 시스템을 적용하여 골프 스윙 동작을 분류하였다. 실시간 골프 스윙 영상에 대해 제안한 방법의 성능 평가를 시행하였고 제안한 방법은 평균 85.2%의 골프 스윙 동작 분류 신뢰도를 보여줌을 확인하였다.

• 지구물리와물리탐사
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• 제14권4호
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• pp.267-273
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• 2011

대륙지각으로부터 해양지각으로의 지각특성 변화가 나타나는 동해연안 해저에서 발생하는 미소지진의 위치를 JHD (Joint Hypocenter Determination) 방법을 사용하여 정밀 재결정하였다. 기상청 국가지진관측망의 지진관측 능력을 충분히 활용하고 지진발생위치 결정에 사용되는 지진의 수를 충분히 확보하기 위하여 연속지진자료를 점검하여, 20 km ${\times}$ 20 km의 연구지역에서 발생하는 56개의 미소지진 자료를 확보하였다. 우선 일반적으로 사용되는 단일진원인자 결정 방법으로 지진의 발생위치를 결정하였으며, 이 결과만으로는 연구지역 해저에 존재하는 해저 구조를 밝혀내기에 충분치 않다. 그러나 JHD 방법을 적용하면, 지진의 발생위치는 공간적 군을 형성하고 지진 발생의 원인이 되는 4개의 단층을 구체적으로 표시한다. 이들 4개의 단층은 2개의 수직으로 분포하는 진원위치와 2개의 가파르게 남쪽으로 경사져서 분포하는 진원위치로 표시된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제34권2호
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• pp.113-118
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• 2008

Temporomandibular joint disorder (TMD) can induce severe pain but, its pathogenic mechanisms remain poorly understood. In this study, we analyzed proteomes of human synovial fluid in the superior joint space in the patients with TMD, which is obtained during the treatment arthrocentesis. We've got this result that one of the spots was consistently down-regulated in synovial fluid of patients with TMD from analysis of protein pattern. Its molecular weight was estimated to be 33 kDa. Synoviolin was identified in our proteomics analysis of LC/MS/MS. This protein was recently reported as one of the proteins that might affect rheumatoid arthritis (RA). Synoviolin that might be associated with RA was detected in synovial fluid of patients with TMD. We can conclude that synoviolin might be involved not only in the pathogenesis of RA but also in TMD. In result, synoviolin might be involved in the pathogenesis of TMD and can be candidates as new therapeutic targets of TMD or early detection biomarkers.

• 융합신호처리학회논문지
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• 제20권3호
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• pp.151-158
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• 2019

재해로 인한 부상 및 만성 질환 등의 다양한 요인으로 신체적 장애를 가진 환자, 혹은 신체의 노화로 인하여 몸의 움직임의 범위가 제한된 노인과 같은 경우, 치료의 일종으로 병원에서의 재활 프로그램의 참여를 권장 받는 경우가 있다. 그러나 이들은 신체의 거동이 불편하므로 보호자의 동행 없이 재활 프로그램의 참여를 위한 이동이 쉽지 않다. 또한, 병원에서는 각각의 환자 및 노인들에게 재활 운동을 지도해주어야 하는 불편함이 존재한다. 이러한 이유로, 이 논문에서는 모션 인식을 통하여 집에서도 타인의 도움 없이 재활 운동이 가능한 원격 재활 프로그램을 개발하였다. 해당 시스템은 사용자 집의 스테레오 카메라와 컴퓨터를 이용하여 구동할 수 있으며, 모션 인식 기능을 통하여 사용자의 실시간 운동 상태 확인이 가능하다. 사용자가 재활 운동에 참여하는 동안, 시스템은 사용자의 특정 부위의 관절가동범위(Joint ROM; Joint Range of Motion)를 저장하여 신체 기능의 향상도를 확인한다. 이 논문에서는 시스템의 검증을 위하여 총 4명의 실험군이 참여하였으며, 총 3종류의 운동을 각 9회씩 반복한 데이터를 이용하여 각 실험군의 시작 및 마지막 운동의 관절가동범위의 차이를 비교하였다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제49권3호
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• pp.125-134
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• 2023

Objectives: The aim of the study was to quantify and compare craniofacial asymmetry in subjects with and without symptoms of temporomandibular joint disorders (TMDs). Materials and Methods: A total of 126 adult subjects were categorized into two groups (63 with a TMDs and 63 without a TMDs), based on detection of symptoms using the Temporomandibular Joint Disorder-Diagnostic Index (TMD-DI) questionnaire. Posteroanterior cephalograms of each subject were traced manually and 17 linear and angular measurements were analyzed. Craniofacial asymmetry was quantified by calculating the asymmetry index (AI) of bilateral parameters for both groups. Results: Intra- and intergroup comparisons were analyzed using independent t-test and Mann-Whitney U test, respectively, with a P<0.05 considered statistically significant. An AI for each linear and angular bilateral parameter was calculated; higher asymmetry was found in TMD-positive patients compared with TMD-negative patients. An intergroup comparison of AIs found highly significant differences for the parameters of antegonial notch to horizontal plane distance, jugular point to horizontal plane distance, antegonial notch to menton distance, antegonial notch to vertical plane distance, condylion to vertical plane distance, and angle formed by vertical plane, O point and antegonial notch. Significant deviation of the menton distance from the facial midline was also evident. Conclusion: Greater facial asymmetry was seen in the TMD-positive group compared with the TMD-negative group. The mandibular region was characterized by asymmetries of greater magnitude compared with the maxilla. Patients with facial asymmetry often require management of temporomandibular joint (TMJ) pathology to achieve a stable, functional, and esthetic result. Ignoring the TMJ during treatment or failing to provide proper management of the TMJ and performing only orthognathic surgery may result in worsening of TMJ-associated symptoms (jaw dysfunction and pain) and re-occurrence of asymmetry and malocclusion. Assessments of facial asymmetry should take into account TMJ disorders to improve diagnostic accuracy and treatment outcomes.

• Asian Pacific Journal of Cancer Prevention
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• 제16권10호
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• pp.4347-4351
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• 2015

Background: Previous studies showed that genetic polymorphisms of glutathione S-transferase P1 (GSTP1) were involved in glutathione metabolism and genetic polymorphisms of ribonucleotide reductase (RRM1) were correlated with DNA synthesis. Here we explored the effects of these polymorphisms on the chemosensitivity and clinical outcome in Chinese non-small cell lung cancer (NSCLC) patients treated with gemcitabine-cisplatin regimens. Materials and Methods: DNA sequencing was used to evaluate genetic polymorphisms of GSTP1 Ile105Val and RRM1 C37A-T524C in 47 NSCLC patients treated with gemcitabine-cisplatin regimens. Clinical response was evaluated according to RECIST criteria after 2 cycles of chemotherapy and toxicity was assessed by 1979 WHO criteria (acute and subacute toxicity graduation criteria in chemotherapeutic agents). Results: There was no statistical significance between sensitive and non-sensitive groups regarding the genotype frequency distribution of GSTP1 Ile105Val polymorphism (p>0.05). But for RRM1 C37A-T524C genotype, sensitive group had higher proportion of high effective genotype than non-sensitive group (p=0.009). And according to the joint detection of GSTP1 Ile105Val and RRM1 C37A-T524C polymorphisms, the proportion of type A (A/A + high effective genotype) was significantly higher in sensitive group than in non-sensitive group (p=0.009). Toxicity showed no correlation with the genotypes between two groups (p>0.05). Conclusions: Compared with single detection of genetic polymorphisms of GSTP1 Ile105Val or RRM1 C37A-T524C, joint detection of both may be more helpful for patients with NSCLC to receive gemcitabine-cisplatin regimens as the first-line chemotherapy. Especially, genetic polymorphism of RRM1 is more likely to be used as an important biomarker to predict the response and toxicity of gemcitabine-cisplatin combination chemotherapy in NSCLC.

• 한국멀티미디어학회논문지
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• 제23권10호
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• pp.1236-1249
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• 2020

In a most recent object tracking research work, applying Convolutional Neural Network and Recurrent Neural Network-based strategies become relevant for resolving the noticeable challenges in it, like, occlusion, motion, object, and camera viewpoint variations, changing several targets, lighting variations. In this paper, the LSTM Network-based Tracking association method has proposed where the technique capable of real-time multi-object tracking by creating one of the useful LSTM networks that associated with tracking, which supports the long term tracking along with solving challenges. The LSTM network is a different neural network defined in Keras as a sequence of layers, where the Sequential classes would be a container for these layers. This purposing network structure builds with the integration of tracking association on Keras neural-network library. The tracking process has been associated with the LSTM Network feature learning output and obtained outstanding real-time detection and tracking performance. In this work, the main focus was learning trackable objects locations, appearance, and motion details, then predicting the feature location of objects on boxes according to their initial position. The performance of the joint object tracking system has shown that the LSTM network is more powerful and capable of working on a real-time multi-object tracking process.

• ETRI Journal
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• 제28권6호
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• pp.721-731
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• 2006

A fast intra skip detection algorithm based on the ratedistortion (RD) cost for an inter frame (P-slices) is proposed for H.264/AVC video encoding. In the H.264/AVC coding standard, a robust rate-distortion optimization technique is used to select the best coding mode and reference frame for each macroblock (MB). There are three types of intra predictions according to profiles. These are $16{\times}16$ and $4{\times}4$ intra predictions for luminance and an $8{\times}8$ intra prediction for chroma. For the high profile, an $8{\times}8$ intra prediction has been added for luminance. The $4{\times}4$ prediction mode has 9 prediction directions with 4 directions for $16{\times}16$ and $8{\times}8$ luma, and $8{\times}8$ chrominance. In addition to the inter mode search procedure, an intra mode search causes a significant increase in the complexity and computational load for an inter frame. To reduce the computational load of the intra mode search at the inter frame, the RD costs of the neighborhood MBs for the current MB are used and we propose an adaptive thresholding scheme for the intra skip extraction. We verified the performance of the proposed scheme through comparative analysis of experimental results using joint model reference software. The overall encoding time was reduced up to 32% for the IPPP sequence type and 35% for the IBBPBBP sequence type.