• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2005년도 춘계학술발표회
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• pp.996-997
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• 2005

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2005년도 춘계학술발표회
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• pp.1010-1011
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• 2005

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2005년도 춘계학술발표회
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• pp.1006-1007
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• 2005

• 공연문화연구
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• 제34호
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• pp.241-276
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• 2017

본 연구에서는 "대악후보"에 악보로 실려 있는 정읍을 부를 수 있는 노래로 복원해 보았다. 먼저 "대악후보" 정읍의 리듬을 찾아 선율을 복원하였고, 복원된 선율에 "악학궤범"의 정읍 가사를 붙여 보았다. 그리고 복원된 정읍이 어떤 음악적 스타일인지도 살펴보았다. 정읍의 리듬은 진작 리듬과 같은 3소박 4박자로 나타났다. 그것은 정읍 장단이 진작 장단을 포함하고 있기 때문이다. 정읍의 장단은 장고점이 한 마디에 한 점씩 나오는 장단인데, 한 박이 3소박으로 되어 있는 점과 한 마디에 장고점 한 점씩 나오는 점은 오늘날의 수제천에 그대로 전해졌다. 정읍의 가사는 같은 장단인 진작1,2와 횡살문을 따라 붙여 보았다. 그 가사붙임에는 다음과 같은 원칙이 나타났다. 가사 한 음보는 선율 두 마디에 붙고, 어단성장이 있으며, 길게 지속하는 음은 어단성장의 장에 해당되는 경우가 많고, 가사는 주로 마디의 첫 음에서 시작되었다. 정읍의 음악적 스타일은 기본적으로 장단이 비슷한 진작1과 비슷하나 약간의 차이는 있다. 가사에 비해 선율의 길이가 매우 길고 같은 음을 길게 지속하는 어단성장의 특성이 강하게 나타나는 점에 있어서는 비슷하다. 그러나 한 가사를 길게 지속할 때 정읍은 간음을 많이 사용하지만 진작은 시김새를 사용하는 점에 있어서는 다르다. "대악후보"에 기보되어 있는 정읍은 이미 변화를 겪어 원 노래에 비해 리듬이 두 배 또는 네 배로 팽창된 것으로 보인다. 리듬이 팽창된 것은 이 노래가 무고 정재의 반주곡으로 사용된 후 무고 무용에 맞추기 위한 것으로 생각된다.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2005년도 춘계학술발표회
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• pp.994-995
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• 2005

• Toxicological Research
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• 제26권3호
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• pp.217-222
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• 2010

Many studies have reported that bleomycin, anti-cancer drug, induces pulmonary fibrosis as a side effect. However, few investigations have focused on the dose-response effects of bleomycin on pulmonary fibrosis. Therefore, in the present study, we investigated the effects of different doses of bleomycin in male mice. ICR mice were given 3 consecutive doses of bleomycin: 1, 2, or 4 mg/kg in bleomycin-treated (BT) groups and saline only in vehicle control (VC) groups. The animals were sacrificed at 7 and 24 days postinstillation. The severity of pulmonary fibrosis was evaluated according to inflammatory cell count and lactate dehydrogenase (LDH) activity in the broncho alveolar lavage fluid (BALF), and lung tissues were histologically evaluated after hematoxylin and eosin (H&E), and Masson's trichrome staining. BT groups exhibited changed cellular profiles in BAL fluid compared to the VC group, which had an increased number of total cells, neutrophils, and lymphocytes and a modest increase in the number of macrophages at 7 days post-bleomycin instillation. Moreover, BT groups showed a dose-dependent increase in LDH levels and inflammatory cell counts. However, at 24 days after treatment, collagen deposition, interstitial thickening, and granulomatous lesions were observed in the alveolar spaces in addition to a decrease in inflammatory cells. These results indicate that pulmonary fibrosis induced by 4 mg/kg bleomycin was more severe than that induced by 1 or 2 mg/kg. These data will be utilized in experimental animal models and as basic data to evaluate therapeutic candidates through non-invasive monitoring using the pulmonary fibrosis mouse model established in this study.

• 한국동물위생학회지
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• 제28권2호
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• pp.99-106
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• 2005

This survey was carried out to investigate the seroprevalence of antibodies to Neospora caninum in Korean indigenous cattle that was representative livestock raised in Jeongeup province Jeonbuk Korea. A total of 1,162 sera were tested for N caninum antibodies using ELISA (Herdcheck anti-Neospora. IDEXX Laboratories Inc., Westbrook, Maine USA). $15(1.3\%)$ sera were positive by ELISA. A total of 290 farms were tested. $11(3.8\%)$ farms were positive. Among the seroprevalence of cattle according to the areas, 8 of 44 counties were infected N caninum. Sero-positive 11 farms of N caninum antibodies using ELISA test and 62 of 301 sera $(20.6\%)$ were infected to N caninum. We found that cattle be raised in Jeongeup province was slightly infected to N caninum. It seems to be infected of N caninum an early stage. but the positive rates was variable that it was $6\%\~62\%$. It was supposed to the highest positive rate of 3 farms had some factors to be infected. The factors were supposed to keep dogs yearly, located the base of hills, and almost feed with imported dried grass. Farmers suppose to the cause of abortion was not the neosporosis but also broke out an accident or was infected Brucella spp. The results of Brucella Rose Bengal Test (RBT) were all negative.

• Toxicological Research
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• 제28권4호
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• pp.217-224
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• 2012

In recent decades, titanium dioxide ($TiO_2$) nanoparticles have been used in various applications, including paints, coatings, and food. However, data are lacking on the toxicological aspects associated with their use. The aim of this study was to assess the inhalation toxicity of $TiO_2$ nanoparticles in rats by using inhalation exposure. Male Wistar rats were exposed to $TiO_2$ nanoparticles for 2 weeks (6 hr/day, 5 days/week) at a mean mass concentration of $11.39{\pm}0.31mg/m^3$. We performed time-course necropsies at 1, 7, and 15 days after exposure. Lung inflammation and injury were assessed on the basis of the total and individual cell counts in bronchoalveolar lavage fluid (BALF), and by biochemical assays, including an assay for lactate dehydrogenase (LDH). Furthermore, histopathological examination was performed to investigate the lungs and nasal cavity of rats. There were no statistically significant changes in the number of BALF cells, results of biochemical assays of BALF and serum, and results of cytokine analysis. However, we did observe histopathological changes in the nasal cavity tissue. Lesions were observed at post-exposure days 1 and 7, which resolved at post-exposure day 15. We also calculated the actual amounts of $TiO_2$ nanoparticles inhaled by the rats. The results showed that the degree of toxicity induced by $TiO_2$ nanoparticles correlated with the delivered quantities. In particular, exposure to small particles with a size of approximately 20 nm resulted in toxicity, even if the total particle number was relatively low.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 제36회 하계학술대회 논문집 D
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• pp.2591-2593
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• 2005

본 연구는 물체의 좌우측 상단에 연결된 와이어로프를 모터 및 드럼을 통하여 감아 올리거나 내려 놓는 과정에서 물체가 수평상태를 유지하여 이동될 수 있도록 Two Motor-Two Drum 형식의 권양기를 제어 하는 권양기의 밸런스제어장치에 관한 것이다. 본 연구에 Two Motor-Two Drum 형식의 권양기 제어장치에 있어서, 물체의 상단에 연견된 일측 와이어로프와 타측 와이어로프의 이동길이를 실시간으로 검출하는 와이어로프 이동길이검출부와, 이 와이어로프 이동길이검출부를 통하여 검출되는 일측 와이어로프와 타측 와이어로프의 이동길이를 비교하여 물체의 기울어진 좌 우 편차를 검출하는 편차검출부와, 이 편차검출부를 통해 검출되는 좌우 편차를 제거하기 위하여 일측 또는 타측 와이어로프가 감겨있는 드럼을 회전시키는 모터의 구동속도를 조절하여 물체를 수평상태로 보정하는 밸런스제어부로 구성 되어 있다.

• 한국동물위생학회지
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• 제32권2호
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• pp.125-129
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• 2009

SBovine tuberculosis is a chronic bacterial disease of animals and humans caused by Mycobacterium bovis. Besides the classical intradermal tuberculin test, a number of blood and serum tests have been used. The purpose of this study was to establish seroprevalence of M. bovis. The sera were screened using the ELISA technique. A total seroprevalence of 65.8% in positive cattle, suspect 36.0%, negative 5.9% in TB-infected herds by PPD and dairy cattle is 3.0%, Hanwoo is 1.6% in TB-free herds. The deer of seroprevalence is 55.0% in TB-infected herd and 7.7% in TB-free herds.