• 대한수의학회지
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• 제49권1호
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• pp.67-71
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• 2009

A 10-year old female Yorkshire terrier with nasal discharge and swelling was referred to the local animal hospital. Abnormal mass of right nasal cavity was detected in physical examination and radiography. According to the radiographs of the head, there was an evidence of bony destruction in right nose. Oronasal fistula was detected in right maxillary canine teeth. After surgical excision, the sample of nasal mass was refereed to Pathology Department of Veterinary Medicine in Jeju National University. Grossly, the enlarged mass was soft and 3 ${\times}$ 3 cm in size. Histopathologically, the neoplastic mass was composed of tubular to tubulopapillary structures which were lined by single to 6~7 layers of cuboidal to ciliated columnar cells. These neoplastic cells showed invasive tendency to adjacent normal parenchyma. They had uniform, round to oval nuclei, cytoplasm with small vacuoles and indistinct cellular margin. The number of mitotic figures was varied in different areas, ranged from 0 to 4 per high power field. Necrotic foci and infiltration of inflammatory cells including neutrophils, lymphocytes, and plasma cells also presented in the mass. Immunohistochemically, the neoplastic cells demonstrated strong positive reaction for cytokeratin (CK) 18 but were negative for CK 7 and 8. Based on the gross, histopathology and immunohistochemistry, this mass was diagnosed as nasal adenocarcinoma originated from respiratory epithelium.

• 한국임상수의학회지
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• 제37권1호
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• pp.23-27
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• 2020

Between May and November 2018, babesiosis was examined in 162 bloods samples obtained to an animal hospital in Jeju island for anemia and medical examination. Sixty-two of 162 (38.3%) were positive by PCR. The ultra fast real-time PCR test with blood directly analyzed without DNA extraction showed the same results. Accurate diagnosis, treatment and prognosis of babesiosis should be combined with clinical symptoms, blood tests, the babesia antibody test, and the PCR antigen test. Ultra fast real-time PCR, with these tests, is expected to be a point-of-care testing (POCT) for easy, fast and accurate diagnosis of babesiosis in the veterinary clinic.

• 대한수의학회지
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• 제54권1호
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• pp.7-12
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• 2014

Peripheral nerve sheath tumors (PNSTs) are heterogeneous tumor groups of peripheral nerves that originate from either Schwann cells or modified Schwann cells, fibroblasts, or perineural cells. In this study, signalment and clinical data such as tumor location and size were evaluated for 15 cases of PNSTs collected from local animal hospitals. The mean age of dogs with malignant PNST was higher than that of dogs with benign PNST. Additionally, the male to female ratio in dogs with PNST was 1 : 4. In dogs with PNST, the primary sites of involvement were the hindlimb, forelimb, around the mammary glands, the neck, and the abdomen. Histiopathologic examination revealed that eight PNSTs were benign and seven were malignant. The tumor cells were composed of loosely to densely arranged interlacing bundles and wavy spindle cells arranged in short bundles, palisading, and whirling. High mitotic figures, local invasion, multifocal necrosis and atypical multinucleated giant cells were observed in malignant PNST cases. All PNSTs showed immunoreactivity for vimentin and S-100. However, only 93.3% and 73.3% were immunoreactive for NSE and GFAP, respectively. Overall, these results indicated that immunohistochemical markers such as vimentin, S-100 and NSE could help confirm the diagnosis of canine PNSTs.

• 대한수의학회지
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• 제49권1호
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• pp.63-66
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• 2009

Cutaneous leiomyomas (leiomyosarcomas) are smooth muscle tumors that occur single or as multiple lesions. They usually arise from the arrector pili muscles (piloleiomyomas) and less commonly from the muscle of veins (angioleiomyomas). This report describes histologic and immunohistochemical features of one cutaneous piloleiomyoma and two angioleiomyosarcomas. Three 7-12-year-old female dogs were presented with single or double cutaneous nodules. Histologically, the neoplastic masses were composed of densely or loosely arranged interlacing bundles. The neoplastic cells were ovoid to elongate, and had eosinophilic cytoplasms and perinuclear cytoplasmic vacuolation. Nuclei were central to eccentric, cigar shaped, oval to elongate. In two cases, high mitotic index in high power field, multifocal necrosis and local invasion were also noted. Masson's trichrome and van Gieson staining revealed muscle origin tumors in these cases. Immunohistochemically, the tumor cells were strongly positive for smooth muscle actin. In our best knowledge, this is the first report of cutaneous smooth muscle tumors in dogs in Korea.

• 한국임상수의학회지
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• 제28권3호
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• pp.314-317
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• 2011

체중이 4.3 kg인 중성화된 16세의 암컷 말티즈견이 약 2주 동안 누런색의 비강과 구강 분비물, 식욕부진과 기면 증상으로 내원하였다. 신체검사에서 구강내 왼쪽 혀 밑 부위에 약 $3{\times}3$ cm 크기의 궤양성 종괴, 심한 치은치주염, 구취, 중등도의 치석, 발열과 아래턱의 연조직 부종을 관찰하였다. 방사선 사진상에서 위턱과 아래턱의 앞 부위에서 골융해 소견을 볼 수 있었다. 총혈액검사와 혈액화학검사에서 혈소판수치, $NH_3$, AST와 ALP의 증가를 관찰할 수 있었으며, 요검사에서 혈뇨와 단백뇨가 나타났다. 조직검사결과 구강 편평 세포암으로 진단되었다. 축주의 거부로 외과적 처치는 실시하지 않았으며, 약물요법으로 carboplatin 주사와 piroxicam 구강내 투여를 병용하였다. 처음 약물투여 후 5일에 지속적인 구토 증상이 나타났으며, 이에 piroxicam을 meloxicam으로 대체하였으며 구토증상은 소실되었다. Meloxicam의 종양에 대한 치료효과에 대한 보고는 흔하지 않지만, 위장관계에 대한 부작용 발생은 piroxicam에 비해 낮음을 알 수 있었다. 이환견은 총 3회의 carboplatin 주사를 실시하였으나, 세 번째 주사 투여 후 5일에 심한 기면증상, 구토와 혈변 증상으로 내원하였고, 검사결과 심한 신기능부전 소견을 보였으며, 축주의 요구에 의해 안락사하였다.

• 한국임상수의학회지
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• 제28권4호
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• pp.460-465
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• 2011

A 15-year-old, castrated male shih-tzu dog was referred to Veterinary Medical Teaching Hospital of Gyeongsang National University due to dyspnea, anorexia, depression of 1 week's duration. On thoracic radiography, triangular shaped soft tissue opacity mass presented in the left cranial lung lobe region. On computed tomography, there was a $3.8{\times}2.5$ cm mass in the left thoracic cavity, which was lobulated and adhered to ventral pleural surface. Histopathologically, the neoplastic cell population consisted of a lot of lymphocytes and a few of Hassal's corpuscles. The immunohistochemistry, lymphocytes were diffusely positive for CD3 and focal positive $CD79{\alpha}$. Based on gross, histologic, and immunohistochemical findings, the neoplasm was diagnosed a lymphocyte predominant thymoma.

• 한국임상수의학회지
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• 제29권4호
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• pp.356-359
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• 2012

암컷, 8년령, 3.2 kg의 시츄견이 간헐적인 구토를 주증으로 내원하였다. 기본 혈액검사 및 방사선 검사에서 특별한 이상 소견은 관찰되지 않았다. 복부 초음파 검사에서 위벽에서 유래한 것으로 생각되는 저에코의 둥근 종괴가 관찰되었다. 위 내시경 검사에서 둥근 종괴가 유문동 벽에서 내강으로 돌출되어 있고, 종괴 및 주변 점막의 비정상적인 소견은 관찰되지 않았다. 이에 위 종괴 절제술을 실시하였고, 면역 염색을 포함한 조직학적 검사에서 extramedullary plasmacytoma로 진단되었다. 환자는 임상 증상이 개선되었으며, 약 2년 동안 재발 및 전이 소견 없이 건강한 상태이다.

• 대한수의학회지
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• 제50권2호
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• pp.133-137
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• 2010

Rabies virus (family Rhabdoviridae, genus Lyssavirus, RV) is the causative agent of rabies in mammals. We conducted a sero-epidemiological survey for RV using sera from South Korean stray and companion dogs in the present study. A total of 533 canine serum samples were collected between February 2006 and December 2007 and were screened for rabies immunity with a neutralizing peroxidase linked assay. Both companion (49.1%) and stray (60.1%) dogs demonstrated RV seropositivity. Regional RV antibody prevalence was measured in the Jeju (87.5%), Gyeonggi (62%), Gyeongsang (59.1%), Jeonra (42%), Chungcheong (37.9%), and Gangwon (30.4%) provinces. Prevalence increased with age but did not exceed 80% in any age group. Stray and companion dogs had RV antibody prevalence values of 26.7% and 23.7%, respectively. Seroprevalence was significantly associated with age $({\chi}2\;=\;9.46;\;p\;=\;0.024)$ for companion dogs, although this association was not evident in stray dogs. There were no significant differences in age between stray and companion dogs and no gender differences in RV seroprevalence. Our results suggested that a widespread and reinforced vaccination program must be applied to Korean dogs.

• 전자공학회논문지
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• 제50권4호
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• pp.182-188
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• 2013

본 논문에서는 정지하고 있는 배경에서 움직이는 목표물을 식별하기 위해 PDR(pulse doppler radar)을 이용하여 수집한 복소수 신호를 처리하는 복소수 SVM(support vector machine)을 제안한다. SVM은 패턴인식 분야에서 널리 이용되나 분류에 이용되는 특징이 대부분 실수 데이터이다. 제안된 복소수 SVM은 실수 데이터, 허수 데이터 정보와 실수부와 허수부 사이의 교차 정보를 모두 이용하여 이동하는 목표물의 분류를 수행한다. 복소수 SVM을 설계하기 위해 최적화 조건 적용 시 실수축과 허수축에 대한 슬랙변수를 고려하였고, 복소수 데이터에 대한 KKT(Karush-Kuhn-Tucker) 조건을 이용하였다. 또한 복소수 거리를 이용한 RBF(radial basis function)를 커널함수로 적용하였다. 제안된 복소수 SVM의 성능을 평가하기 위해 PDR 센서로 수집된 복소 데이터를 기존의 SVM과 복소수 SVM을 이용하여 분류한 결과 기존의 SVM에 비해 복소수 SVM의 식별결과가 개와 사람 각각 8%, 10% 향상되었다.

• 복식
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• 제58권9호
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• pp.114-128
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• 2008

The current study aims to classify types of traditional fur Garments in Jeju into Dusik(hat), dress, Jokui(socks) and accessaries, and examine characteristics of them through demonstrative study focusing on collections of museums in Jeju. Dusik is a kind of hat for protection against the cold, and there are badger leather Gamtaes and cow hair Beonggeojis(fur hats). Especially leather gamtae was used to protect against the cold when people hunted roe deers in Mt. Halla. Beonggeoji was producted in the form of felt with fine hair collected coat-shedding of cows and dogs in spring, therefore it was too warm and practical to be damaged from storm or pressure. Fur coat is a general name of dress made of leather without hair. It is a kind of clothes with a hat worn while taking care of horses and cows. Also people wore dog leather topcoats and cow leather topcoats when they hunted in Mt. Halla. As for Jokui, there are leather Beoseon(socks) made of cow leather, leather shoes in the form of straw shoes, and leather Balle embracing the low half of the body warmly. Accessaries include a rectangular cow leather bag for storing an iron piece for making fire. These traditional fur robs in Jeju not only have practicality for protection against the cold, but also symbolized richness by using leathers of badgers, roe deers, etc. that were previous during that times. Also they used partially cut leather for decoration at the edge.