• Archives of Plastic Surgery
• /
• 제40권6호
• /
• pp.715-720
• /
• 2013

Background Many people have an interest in the correction of facial scars or deformities caused by trauma. The increasing ability to correct such flaws has been one of the reasons for the increase in the popularity of facial plastic surgery. In addition to its roles in communication, breathing, eating, olfaction and vision, the appearance of the face also plays an important role in human interactions, including during social activities. However, studies on the importance of the functional role of facial appearance. As a function of the face are scare. Therefore, in the present study, we evaluated the importance of the functions of the face in Korea. Methods We conducted an online panel survey of 300 participants (age range, 20-70 years). Each respondent was administered the demographic data form, Facial Function Assessment Scale, Rosenberg Self-Esteem Scale, and standard gamble questionnaires. Results In the evaluation on the importance of facial functions, a normal appearance was considered as important as communication, breathing, speech, and vision. Of the 300 participants, 85% stated that a normal appearance is important in social activities. Conclusions The results of this survey involving a cross-section of the Korean population indicated that a normal appearance was considered one of the principal facial functions. A normal appearance was considered more important than the functions of olfaction and expression. Moreover, a normal appearance was determined to be an important facial function for leading a normal life in Korea.

• Toxicological Research
• /
• 제20권1호
• /
• pp.43-47
• /
• 2004

In order to investigate the safety of a water extract (ADP) of 1 : 1 mixture of Anemarrhena rhizoma and Phellodendron cortex for alleviating benign prostate hyperplasia, genotoxicity studies in bacterial and mammalian cell assay systems, namely, the Ames bacterial reverse mutation and chromosomal aberration assays were performed. As shown by the results of the Ames bacterial reversion assay, ADP in the range of 625-5000 $\mu\textrm{g}$/plate did not induce mutagenicity in Salmonella typhimurium TA 98, TA 100, TA 1535 and TA 1537 strains in the absence or in the presence of S9 (the microsomal fraction of rat liver homogenate) metabolic activation. The $IC_{50}$ (50% cell growth inhibition concentration) values of ADP for the chromosomal aberration assay were determined; these were 2425 $\mu\textrm{g}$/ml in the absence and 8126 $\mu\textrm{g}$/ml in the presence of S9 metabolic activation in Chinese hamster lung (CHL) fibroblast cell culture. No chromosomal aberration was observed in CHL cells treated with ADP at 2425, 1212.5 and 606.25 $\mu\textrm{g}$/ml in the absence, or at 8126, 4063 and 2031.5 $\mu\textrm{g}$/ml in the presence of S9 metabolic activation. These results show that under the conditions used, ADP does not harmfully affect the bacterial or mammalian cell system at the gene level.

• Proceedings of the Korea Water Resources Association Conference
• /
• 한국수자원학회 2011년도 학술발표회
• /
• pp.26-30
• /
• 2011

최근 기후변화에 따라 강우의 패턴이 변화하고 있다. 강우일수는 줄어드는 반면, 강우강도는 증가하여, 홍수로 인한 많은 피해에 직면하고 있다. 이러한 기상이변은 홍수방어시스템을 위한 수공구조물에도 많은 영향을 미친다. 수공구조물을 설계할 때, 일반적으로 강우 기록들의 통계적 특성이 정상성을 가진다고 가정한다. 하지만 최근의 강우 자료를 분석하면, 시간에 따라 평균, 분산, 왜곡도와 같은 기본 통계량이 변화하는 것을 알 수 있다. 따라서, 수공구조물의 설계를 위한 확률 강우량은 이러한 기후변화에 따른 자료의 특성을 반영할 필요가 있다. 본 연구의 목적은 강우 자료의 비정상성의 특성을 이용하여 확률강우량을 산정하는 것이다. 최근 비정상성 강우빈도해석에 대한 연구가 활발히 진행되고 있는데, 이들 연구는 대부분 목표연도까지 경향성의 기울기가 증가, 또는 일정하다고 가정한다. 하지만, 현재는 경향성이 있지만, 목표연도에는 경향성이 없을 경우도 있고, 또는 경향성이 있어도 그 기울기가 적어지는 경향을 보일 수도 있다. 본 연구에서는 현시점과 목표연도의 시점에 대한 경향성 기울기의 변화를 고려하여 비정상성 강우빈도해석을 수행하였다. 대상지점 선정은 통계적 경향성 검정, Mann-Kendall test를 이용하여 1994년(현재시점)에 경향성이 있다고 판단되는 관측지점을 대상지점으로 선정하였다. 분석 방법은 24시간 임계지속시간의 연최대강우자료를 구축하였다. 자료를 현시점까지 선형회귀식을 이용하여 잔차 계열을 산정하고, Gumbel 분포를 이용하여 확률 잔차를 산정하였다. 확률강우량을 추정하기 위해 추세요소를 산정하였다. 기울기의 증가 혹은 감소 경향을 회귀모형을 이용하여 추세요소를 산정하였고, 잔차의 확률빈도와 추세요소의 합으로 비정상상 확률강우량을 산정하였다.

• The Journal of the Korea Contents Association
• /
• 제11권11호
• /
• pp.503-513
• /
• 2011

Appreciation of nature and an understanding of the biological sciences by the general public are key to the popularization of modern science. In particular, informal and accessible venues such as museum exhibits occupy a crucial role in science education, and they depend heavily on fields related to macrobiology, including Ecology, Animal Behavior, and Environmental Science. Unfortunately, lack of engaged experts and superficial descriptions of natural phenomena all too often prevent scientific knowledge from being shared effectively with the general public. Raw information itself and knowledge are not in a form or structure accessible to nonspecialists. In order to move successfully deliver substantive comprehension of the biological knowledge to the general public, it is necessary to categorize information from a content-conscious perspective and transform it into useful biological content. Therefore, the role of scientists is critically important in a series of processes that include theme selection, editing, and even graphical layout of contents. These processes require not only a scientific and logical way of thinking, but also an aptitude for artistic presentation and effective communication. The concept of Translation is presented as a theoretical and operational framework for the popularization of science.

• Journal of Plant Biotechnology
• /
• 제43권3호
• /
• pp.341-346
• /
• 2016

The objectives of this study were to 1) evaluate the efficiency of the protocol of Agrobacterium-mediated transformation of cucumber to introduce phytoene synthase-2a carotene desaturase (PAC genes); 2) demonstrate the integration of PAC genes into the genome of putative transgenic cucumber based on growth on selection medium, PCR and Southern analysis; 3) evaluate the expression of PAC genes in transgenic cucumber based on the analysis of RT-PCR and Northern blot hybridization. Out of 5,945 cotyledonary-node explants inoculated with Agrobacterium, 65 (1.1%) explants produced 238 shoots. Integration of PAC genes into the genome of the cucumber was demonstrated based on the analysis of gDNA-PCR, 21 out of the 238 plants regenerated; while 6 plants proved positive for Southern blot hybridization. Transgene expression was demonstrated based on analysis of RT-PCR, 6 plants proved positive out of the 6 plants analyzed; while 4 plants out of 6 proved positive during Northern blot hybridization. This study successfully demonstrated the production of transgenic cucumber, integration, and expression of the PAC gene in cucumber.

• Journal of Applied Biological Chemistry
• /
• 제44권2호
• /
• pp.59-64
• /
• 2001

Pepper plants (Nogkwang, 60-day old) were inoculated with Phytophthora capsici to induce sesquiterpene cyclase associated with the biosynthesis of phytoalexin (capsidiol), a substance related to the defense against pathogens in plants. One day after inoculation, mRNA was isolated from the root, cDNA synthesized, and a library constructed in a ZAP express XR vector. The efficiency was $2{\times}10^6pfu/{\mu}g$. Sesquiterpene cyclase cDNA from Hyoscyamus muticus was labeled with $^{32}P$ and used as a probe for screening the cDNA library. After the third screening, 25 positive clones were selected. Through restrictive digestion and DNA gel-blot analysis, six different cyclase gene expressions were identified. PSC1B sequences of the six clones were determined, which were 1966 base pairs encoded 556 amino acids with an expected molecular weight of 63.8 kDa. Response against the pathogen was different between the resistant and susceptible peppers. After the infection of the pathogen, the expression of PSC genes continued in the resistant peppers while the plants were alive. The expression in the susceptible peppers lasted for only 4 days.

• Proceedings of the KAIS Fall Conference
• /
• 한국산학기술학회 2008년도 추계학술발표논문집
• /
• pp.350-353
• /
• 2008

과산화물 가교제의 농도가 헬리콥터 연료탱크의 자기밀폐층 소재로 적용시키기 위한 천연고무 스폰지의 팽윤에 미치는 효과를 조사하였다. 천연고무 콤파운드를 Kneader와 Roll-Mill을 활용하여 제조하고, 고압조건의 프레스에서 부분 가교시킨 후 대기압의 금형에서 발포와 완전가교를 실시하였다. 얻어진 스폰지의 겉보기밀도를 측정하고 스폰지의 셀구조를 주사전자현미경을 통하여 관찰하였다. 톨루엔, 이소옥탄과 항공유를 사용하여 실온에서 팽윤실험을 실시하였다. 용매에 2분 동안 침적 후 얻어지는 부피팽윤비 값은 과산화물 농도가 감소함에 따라 증가하다가 감소하는 경향을 보였다. 스폰지의 겉보기밀도와 셀구조는 과산화물 함량에 매우 민감하였으며 이는 또한 천연고무 스폰지의 팽윤거동에 영향을 미쳤다. 천연고무 스폰지가 연료와 접촉하여 신속한 팽윤이 얻어지기 위하여 금형에서 동시에 발생하는 두 가지 반응인 발포제의 분해반응과 천연고무의 가교반응을 적절히 조절하는 것이 중요하다.

• Journal of Preventive Medicine and Public Health
• /
• 제35권3호
• /
• pp.263-268
• /
• 2002

Objective : This study was aiming at estimating the joint effects of various risk factors associated with uterine cervix cancer in Korea. Methods : Data obtained from a case-control study were analyzed with a multiplicative model. Results : After adjustment for age and husband's educational attainments, the family history of cervical cancer (OR=2.1, 95% CI=1.2-3.9), unstable marital status due to separation, by death or divorce, etc. (OR=2.8, 95% CI=1.7-4.6), and a large number of deliveries ($\geq$3 vs. nulliparous OR=6.5, 55% CI=1.4-29.0) increased the risk of uterine cervix cancer, Conversely, first sexual intercourse at an older age ($\geq$25 years vs. <19 years OR=0.4, 95% CI=0.2-0.6) and husband's circumcision (OR=0.7, 95% CI=0.5-1.0) decreased the risk. In the multiplicative model, the highest joint risk (OR=39.2, 95% CI 5.9-258.9) was observed in women with a family history of uterine cervical cancer, an unstable marital status, where the ex-husband was not circumcised, with 3 or more delivery experiences, and having her first sexual intercourse when younger than 19 years of age. However, women without a family history of uterine cervix cancer, married to a circumcised husband, having had her first sexual intercourse at 25 years or older, and nulliparous, showed the lowest joint effect (OR=0.3, 95% CI=0.1-0.5). Conclusion : As carcinogenesis is a complex action involving various factors, we consider a joint effects approach to be appropriate in an epidemiological study on risk factors for uterine cervix neoplasms cervix neoplasm.

• Journal of Physiology & Pathology in Korean Medicine
• /
• 제22권2호
• /
• pp.385-389
• /
• 2008

Nitric oxide (NO) has been suggested to play an important role in endotoxin-mediated shock and inflammation. In this study, we investigated the effect of Rosa laevigata Michx. (Rosaceae) on the production of NO and the molecular mechanism of its action. Rosa laevigata inhibited NO generation and iNOS expression in LPS-stimulated murine macrophages. Activity of nuclear $factor{-\kappa}B\;(NF{-\kappa}B)$ and the degradation of $I{\kappa}B-{\alpha}$ were suppressed by Rosa laevigata. Furthermore, extracellular signal-stimulated kinase (ERK), which is known to be involved in $NF{-\kappa}B$ activation, is inhibited by Rosa laevigata. These results suggest that Rosa laevigata could exert its anti-inflammatory actions by suppressing the synthesis of NO through inhibition of $NF{-\kappa}B$ activity.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• 제38권8호
• /
• pp.806-812
• /
• 2010

Fuel tanks for rotorcraft have a great influence on the survivability of crews. The philosophy of crashworthy rotorcraft design evolved from the long term effort of the US Army. US army established MIL-DTL-27422D for specifying detail requirements related to crash resistant fuel tank especially for military rotorcraft to prevent post crash fire which is the greatest threat to life in rotorcraft crash. Crashworthiness of the rotorcraft fuel tank could be guaranteed through the crash impact tests which are specified in the MIL-DTL-27422D. Fuel tanks for Korea Helicopter Program have been developed and tested according to MIL-DTL-27422D with minor modifications of flexible fittings. The present study shows some results of the mandatory crash impact tests of the fuel tanks to verify their performances.